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| 12. |  | SANTOS, V. M. C. S.; PINTO, M. A. S.; BIZZO, H. R.; DESCHAMPS, C. Seasonal variation of vegetative growth, essential oil yield and composition of menthol mint genotypes at southern Brazil. Bioscience Journal, Uberlândia, v. 28, n. 5, p. 790-798, Sept./Oct. 2012.| Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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| 15. | | PINTO, M. A. B.; PARFITT, J. M. B.; NEMITZ, A. M. J.; SCIVITTARO, W. B.; WINKLER, A. S. Physical attributes of a chernosol on the west border of rio grande do sul cultivated with rice in two cultivation and irrigation systems. In: ISTRO CONFERENCE, 19.; SUCS MEETING, 4., 2012, Montevideo. Striving for sustainable high productivity. [S.l.]: ISTRO, 2012.| Biblioteca(s): Embrapa Clima Temperado. |
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| 17. | | PENNING, L. H.; PINTO, M. A. B.; TIMM, L. C.; PARFITT, J. M. B.; SCIVITTARO, W. B.; FARIA, L. C. Estabilidade temporal da umidade do solo. In: CONGRESSO BRASILEIRO DE ENGENHARIA AGRÍCOLA, 43., 2014, Campo Grande-MS. Resumos expandidos... Campo Grande-MS: SBEA, 2014. CONBEA 2014.| Biblioteca(s): Embrapa Clima Temperado. |
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| 18. | | DESCHAMPS, C.; AMARAL, W. do; BIZZO, H. R.; PINTO, M. A. S.; BIASI, L. A.; SILVA, L. E. da. Essential oils yield and composition of Myrtaceae species from Atlantic Forest of South Brazil. Natural Volatiles & Essential Oils, v. 4, n. 3, 2017. p. 63 Edition of Abstracts of the 48th International Symposium on Essential Oils, Pécs, Hungary, 2017. Abstracts. Babedio, 2017. ISEO 2017, 10 a 13 set. 2017. OP-15.| Biblioteca(s): Embrapa Agroindústria de Alimentos; Embrapa Gado de Leite. |
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| 20. | | AMARAL, W. do; DESCHAMPS, C.; BIZZO, H. R.; PINTO, M. A. S.; BIASI, L. A.; SILVA, L. E. Essential Oil Yield and Composition of Native Tree Species from Atlantic Forest, South of Brazil. Journal of Essential Oil Bearing Plants, v. 20, n. 6, p. 1525-1535, dec. 2017.| Biblioteca(s): Embrapa Agroindústria de Alimentos; Embrapa Gado de Leite. |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Mandioca e Fruticultura. Para informações adicionais entre em contato com cnpmf.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Mandioca e Fruticultura. |
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Data corrente: |
25/09/2018 |
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Data da última atualização: |
25/09/2018 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
GUEDES, J. A. C.; ALVES FILHO, E. G.; RODRIGUES, T. H. S.; SILVA, M. F. S.; SOUZA, F. V. D.; SILVA, L. M. A. e; ALVES, R. E.; CANUTO, K. M.; BRITO, E. S. de; PESSOA, C. O.; NASCIMENTO, R. F.; ZOCOLO, G. J. |
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Afiliação: |
Jhonyson Arruda Carvalho Guedes, Universidade Federal do Ceará; Elenilson de Godoy Alves Filho, Embrapa Agroindústria Tropical (bolsista); TIGRESSA HELENA SOARES RODRIGUES, CNPAT; Maria Francilene Souza Silva, Universidade Federal do Ceará; FERNANDA VIDIGAL DUARTE SOUZA, CNPMF; LORENA MARA ALEXANDRE E SILVA, CNPAT; RICARDO ELESBAO ALVES, CNPAT; KIRLEY MARQUES CANUTO, CNPAT; EDY SOUSA DE BRITO, CNPAT; Cláudia do Ó Pessoa, Universidade Federal do Ceará; Ronaldo Ferreira Nascimento, Universidade Federal do Ceará; GUILHERME JULIAO ZOCOLO, CNPAT. |
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Título: |
Metabolic profile and cytotoxicity of non-polar extracts of pineapple leaves and chemometric analysis of different pineapple cultivars. I |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Industrial Crops and Products, v. 124, p. 466-474, 2018. |
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Idioma: |
Inglês |
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Conteúdo: |
The use of co-products from the fruit agroindustry as a source of bioactive molecules presents economic advantages, since these compounds are highly available and inexpensive. Therefore, the present study aimed to evaluate their qualitative chemical composition followed by multivariate analysis, and to correlate the results with those of the cytotoxicity tests. The non-polar metabolic profiles of the leaves of seven commercial pineapple (Ananas comosus (L.) Merr.) cultivars were investigated by using GC?MS. Twenty-seven metabolites were identified from the seven hexanic extracts. Multivariate analysis (Hierarchical Cluster Analysis, Principal Component Analysis and Partial Least Squares) revealed significant differences in the metabolic fingerprint of the different cultivars. Overall, the hexanic extracts of the seven cultivars of pineapple leaves showed promising antitumor activity against the six tumor lines tested (colon, leukemia, prostate, astrocytoma, breast and cervix). Correlation of the chemometric data, qualitative analysis, and cytotoxic tests allowed us to determine the possible biomarkers responsible for each specific antitumor activity. This study demonstrates a great valuation potential of a co-product little explored in the agroindustry of foods through the prospection of biologically active compounds. |
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Palavras-Chave: |
GC MS. |
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Thesagro: |
Abacaxi. |
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Thesaurus NAL: |
Ananas; Cytotoxicity; Multivariate analysis. |
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Categoria do assunto: |
-- |
|
Marc: |
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001 2096234
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100 1 $aGUEDES, J. A. C.
245 $aMetabolic profile and cytotoxicity of non-polar extracts of pineapple leaves and chemometric analysis of different pineapple cultivars. I$h[electronic resource]
260 $c2018
520 $aThe use of co-products from the fruit agroindustry as a source of bioactive molecules presents economic advantages, since these compounds are highly available and inexpensive. Therefore, the present study aimed to evaluate their qualitative chemical composition followed by multivariate analysis, and to correlate the results with those of the cytotoxicity tests. The non-polar metabolic profiles of the leaves of seven commercial pineapple (Ananas comosus (L.) Merr.) cultivars were investigated by using GC?MS. Twenty-seven metabolites were identified from the seven hexanic extracts. Multivariate analysis (Hierarchical Cluster Analysis, Principal Component Analysis and Partial Least Squares) revealed significant differences in the metabolic fingerprint of the different cultivars. Overall, the hexanic extracts of the seven cultivars of pineapple leaves showed promising antitumor activity against the six tumor lines tested (colon, leukemia, prostate, astrocytoma, breast and cervix). Correlation of the chemometric data, qualitative analysis, and cytotoxic tests allowed us to determine the possible biomarkers responsible for each specific antitumor activity. This study demonstrates a great valuation potential of a co-product little explored in the agroindustry of foods through the prospection of biologically active compounds.
650 $aAnanas
650 $aCytotoxicity
650 $aMultivariate analysis
650 $aAbacaxi
653 $aGC MS
700 1 $aALVES FILHO, E. G.
700 1 $aRODRIGUES, T. H. S.
700 1 $aSILVA, M. F. S.
700 1 $aSOUZA, F. V. D.
700 1 $aSILVA, L. M. A. e
700 1 $aALVES, R. E.
700 1 $aCANUTO, K. M.
700 1 $aBRITO, E. S. de
700 1 $aPESSOA, C. O.
700 1 $aNASCIMENTO, R. F.
700 1 $aZOCOLO, G. J.
773 $tIndustrial Crops and Products$gv. 124, p. 466-474, 2018.
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