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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sul. Para informações adicionais entre em contato com cppsul.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sul. |
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Data corrente: |
25/10/2021 |
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Data da última atualização: |
10/12/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
COMIN, H. B.; SOLLERO, B. P.; GASPAR, E. B.; DOMINGUES, R.; CARDOSO, F. F. |
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Afiliação: |
H. B. COMIN, UFPEL; BRUNA PENA SOLLERO, CPPSUL; EMANUELLE BALDO GASPAR, CPPSUL; ROBERT DOMINGUES, CPPSUL; FERNANDO FLORES CARDOSO, CPPSUL. |
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Título: |
Genome-wide association study of resistance/susceptibility to infectious bovine keratoconjunctivitis in Brazilian Hereford cattle. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Animal Genetics, v. 52, n. 6, p. 881-886, Dec. 2021. |
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Idioma: |
Inglês |
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Conteúdo: |
Genome-wide association studies were conducted to identify the more informative genomic regions and SNPs, as well as to identify candidate genes associated with infectious bovine keratoconjunctivitis (IBK) resistance/susceptibility in Hereford cattle. A Bayes B statistical approach was initially applied in genome-wide association studies by using deregressed estimated breeding values for IBK resistance/susceptibility. To estimate the combined effect of a genomic region that is potentially associated with QTL, 2504 non-overlapping 1-Mb windows that varied in SNP number were defined, with the most informative 24 windows including 427 SNPs and explaining more than 20% of the estimated genetic variance for IBK resistance/susceptibility. These regions were explored with respect to their biological functions through functional analysis to map potential candidate genes. The significant SNPs were mapped on chromosomes 1, 3, 5, 6, 7, 8, 10, 11, 12, 13, 14, 15, 18, 20, 23, and 28, and candidate genes were detected as related to the IBK. Most informative SNPs in term of genetic variance were located in proximity of genes related to phenotypic expression of lesions and biological processes associated to the IBK. Knowledge about phenotypic and genomic variation generated in the present study can be used to on design selection strategies to improve the resistance to IBK of Hereford cattle herds. Keywords Bayesian inference, beef cattle, candidate genes, functional analysis |
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Thesagro: |
Conjuntivite; Doença Animal; Olho; Queratite. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02152naa a2200217 a 4500
001 2135552
005 2021-12-10
008 2021 bl uuuu u00u1 u #d
100 1 $aCOMIN, H. B.
245 $aGenome-wide association study of resistance/susceptibility to infectious bovine keratoconjunctivitis in Brazilian Hereford cattle.$h[electronic resource]
260 $c2021
520 $aGenome-wide association studies were conducted to identify the more informative genomic regions and SNPs, as well as to identify candidate genes associated with infectious bovine keratoconjunctivitis (IBK) resistance/susceptibility in Hereford cattle. A Bayes B statistical approach was initially applied in genome-wide association studies by using deregressed estimated breeding values for IBK resistance/susceptibility. To estimate the combined effect of a genomic region that is potentially associated with QTL, 2504 non-overlapping 1-Mb windows that varied in SNP number were defined, with the most informative 24 windows including 427 SNPs and explaining more than 20% of the estimated genetic variance for IBK resistance/susceptibility. These regions were explored with respect to their biological functions through functional analysis to map potential candidate genes. The significant SNPs were mapped on chromosomes 1, 3, 5, 6, 7, 8, 10, 11, 12, 13, 14, 15, 18, 20, 23, and 28, and candidate genes were detected as related to the IBK. Most informative SNPs in term of genetic variance were located in proximity of genes related to phenotypic expression of lesions and biological processes associated to the IBK. Knowledge about phenotypic and genomic variation generated in the present study can be used to on design selection strategies to improve the resistance to IBK of Hereford cattle herds. Keywords Bayesian inference, beef cattle, candidate genes, functional analysis
650 $aConjuntivite
650 $aDoença Animal
650 $aOlho
650 $aQueratite
700 1 $aSOLLERO, B. P.
700 1 $aGASPAR, E. B.
700 1 $aDOMINGUES, R.
700 1 $aCARDOSO, F. F.
773 $tAnimal Genetics$gv. 52, n. 6, p. 881-886, Dec. 2021.
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Registro original: |
Embrapa Pecuária Sul (CPPSUL) |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Gado de Corte. Para informações adicionais entre em contato com cnpgc.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Gado de Corte. |
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Data corrente: |
13/12/1993 |
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Data da última atualização: |
13/12/1993 |
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Autoria: |
SILVA, L. O. C. da; ROSA, A. do N.; NOBRE, P. R. C.; FIGUEIREDO, G. R. de; MILAGRES, J. C. |
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Afiliação: |
EMBRAPA. Centro Nacional de Pesquisa de Gado de Corte (Campo Grande, MS). |
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Título: |
Pesos corporais da raca Nelore no Brasil, segundo aspectos de meio. |
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Ano de publicação: |
1984 |
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Fonte/Imprenta: |
In: REUNIAO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 21., 1984, Belo Horizonte. Anais... Belo Horizonte : SBZ, 1984. |
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Páginas: |
p.145. |
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Idioma: |
Português |
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Notas: |
CNPGC. |
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Palavras-Chave: |
Ambiente; Brasil; Breed; Environmental; Nelore. |
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Thesagro: |
Bovino; Peso; Raça. |
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Thesaurus NAL: |
Brazil; cattle; Nellore; weight. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 00859naa a2200325 a 4500
001 1320864
005 1993-12-13
008 1984 bl uuuu u00u1 u #d
100 1 $aSILVA, L. O. C. da
245 $aPesos corporais da raca Nelore no Brasil, segundo aspectos de meio.
260 $c1984
300 $ap.145.
500 $aCNPGC.
650 $aBrazil
650 $acattle
650 $aNellore
650 $aweight
650 $aBovino
650 $aPeso
650 $aRaça
653 $aAmbiente
653 $aBrasil
653 $aBreed
653 $aEnvironmental
653 $aNelore
700 1 $aROSA, A. do N.
700 1 $aNOBRE, P. R. C.
700 1 $aFIGUEIREDO, G. R. de
700 1 $aMILAGRES, J. C.
773 $tIn: REUNIAO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 21., 1984, Belo Horizonte. Anais... Belo Horizonte : SBZ, 1984.
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Embrapa Gado de Corte (CNPGC) |
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