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| 4. |  | COSTA, R. V. da; COTA, L. V.; CASELA, C. R. Manejo de doenças. In: CRUZ, J. C.; MAGALHAES, P. C.; PEREIRA FILHO, I. A.; MOREIRA, J. A. A. (Ed.). Milho: o produtor pergunta, a Embrapa responde. Brasília, DF: Embrapa Informação Tecnológica; Sete Lagoas: Embrapa Milho e Sorgo, 2011. cap. 10, p. 137-169. (Coleção 500 perguntas, 500 respostas).| Biblioteca(s): Embrapa Milho e Sorgo. |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Suínos e Aves. Para informações adicionais entre em contato com cnpsa.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
05/12/2014 |
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Data da última atualização: |
05/12/2014 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
SCHAEFER, R.; RECH, R. R.; GAVA, D.; CANTAO, M. E.; SILVA, M. C. da; SILVEIRA, S.; ZANELLA, J. R. C. |
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Afiliação: |
REJANE SCHAEFER, CNPSA; RAQUEL RUBIA RECH, CNPSA; DANIELLE GAVA, CNPSA; MAURICIO EGIDIO CANTAO, CNPSA; MARCIA CRISTINA DA SILVA, CEDISA; SIMONE SILVEIRA, UFRGS; JANICE REIS CIACCI ZANELLA, CNPSA. |
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Título: |
A human-like H1N2 influenza virus detected during an outbreak of acute respiratory disease in swine in Brazil. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
Archives of virology, 2014. |
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DOI: |
10.1007/s00705-014-2223-z |
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Idioma: |
Inglês |
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Conteúdo: |
Passive monitoring for detection of influenza A viruses (IAVs) in pigs has been carried out in Brazil since 2009, detecting mostly the A(H1N1)pdm09 influenza virus. Since then, outbreaks of acute respiratory disease suggestive of influenza A virus infection have been observed frequently in Brazilian pig herds. During a 2010-2011 influenza monitoring, a novel H1N2 influenza virus was detected in nursery pigs showing respiratory signs. The pathologic changes were cranioventral acute necrotizing bronchiolitis to subacute proliferative and purulent bronchointerstitial pneumonia. Lung tissue samples were positive for both influenza A virus and A(H1N1)pdm09 influenza virus based on RT-qPCR of the matrix gene. Two IAVs were isolated in SPF chicken eggs. HI analysis of both swine H1N2 influenza viruses showed reactivity to the H1d cluster. DNA sequencing was performed for all eight viral gene segments of two virus isolates. According to the phylogenetic analysis, the HA and NA genes clustered with influenza viruses of the human lineage (H1-d cluster, N2), whereas the six internal gene segments clustered with the A(H1N1)pdm09 group. This is the first report of a reassortant human-like H1N2 influenza virus derived from pandemic H1N1 virus causing an outbreak of respiratory disease in pigs in Brazil. The emergence of a reassortant IAV demands the close monitoring of pigs through the fullgenome sequencing of virus isolates in order to enhance genetic information about IAVs circulating in pigs. MenosPassive monitoring for detection of influenza A viruses (IAVs) in pigs has been carried out in Brazil since 2009, detecting mostly the A(H1N1)pdm09 influenza virus. Since then, outbreaks of acute respiratory disease suggestive of influenza A virus infection have been observed frequently in Brazilian pig herds. During a 2010-2011 influenza monitoring, a novel H1N2 influenza virus was detected in nursery pigs showing respiratory signs. The pathologic changes were cranioventral acute necrotizing bronchiolitis to subacute proliferative and purulent bronchointerstitial pneumonia. Lung tissue samples were positive for both influenza A virus and A(H1N1)pdm09 influenza virus based on RT-qPCR of the matrix gene. Two IAVs were isolated in SPF chicken eggs. HI analysis of both swine H1N2 influenza viruses showed reactivity to the H1d cluster. DNA sequencing was performed for all eight viral gene segments of two virus isolates. According to the phylogenetic analysis, the HA and NA genes clustered with influenza viruses of the human lineage (H1-d cluster, N2), whereas the six internal gene segments clustered with the A(H1N1)pdm09 group. This is the first report of a reassortant human-like H1N2 influenza virus derived from pandemic H1N1 virus causing an outbreak of respiratory disease in pigs in Brazil. The emergence of a reassortant IAV demands the close monitoring of pigs through the fullgenome sequencing of virus isolates in order to enhance genetic information about IAVs circulating i... Mostrar Tudo |
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Palavras-Chave: |
H1N1. |
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Thesagro: |
Doença respiratória. |
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Thesaurus NAL: |
Influenza A virus. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02207naa a2200241 a 4500
001 2001836
005 2014-12-05
008 2014 bl uuuu u00u1 u #d
024 7 $a10.1007/s00705-014-2223-z$2DOI
100 1 $aSCHAEFER, R.
245 $aA human-like H1N2 influenza virus detected during an outbreak of acute respiratory disease in swine in Brazil.$h[electronic resource]
260 $c2014
520 $aPassive monitoring for detection of influenza A viruses (IAVs) in pigs has been carried out in Brazil since 2009, detecting mostly the A(H1N1)pdm09 influenza virus. Since then, outbreaks of acute respiratory disease suggestive of influenza A virus infection have been observed frequently in Brazilian pig herds. During a 2010-2011 influenza monitoring, a novel H1N2 influenza virus was detected in nursery pigs showing respiratory signs. The pathologic changes were cranioventral acute necrotizing bronchiolitis to subacute proliferative and purulent bronchointerstitial pneumonia. Lung tissue samples were positive for both influenza A virus and A(H1N1)pdm09 influenza virus based on RT-qPCR of the matrix gene. Two IAVs were isolated in SPF chicken eggs. HI analysis of both swine H1N2 influenza viruses showed reactivity to the H1d cluster. DNA sequencing was performed for all eight viral gene segments of two virus isolates. According to the phylogenetic analysis, the HA and NA genes clustered with influenza viruses of the human lineage (H1-d cluster, N2), whereas the six internal gene segments clustered with the A(H1N1)pdm09 group. This is the first report of a reassortant human-like H1N2 influenza virus derived from pandemic H1N1 virus causing an outbreak of respiratory disease in pigs in Brazil. The emergence of a reassortant IAV demands the close monitoring of pigs through the fullgenome sequencing of virus isolates in order to enhance genetic information about IAVs circulating in pigs.
650 $aInfluenza A virus
650 $aDoença respiratória
653 $aH1N1
700 1 $aRECH, R. R.
700 1 $aGAVA, D.
700 1 $aCANTAO, M. E.
700 1 $aSILVA, M. C. da
700 1 $aSILVEIRA, S.
700 1 $aZANELLA, J. R. C.
773 $tArchives of virology, 2014.
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