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| Registros recuperados : 407 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Algodão. |
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Data corrente: |
28/03/2023 |
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Data da última atualização: |
28/03/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
MASSARIOLI, A. P.; SARTORI, A. G. de O.; JULIANO, F. F.; AMARAL, J. E. P. G. do; SANTOS, R. C. dos; LIMA, L. M. de; ALENCAR, S. M. de. |
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Afiliação: |
ADNA PRADO MASSARIOLI, ESALQ; ALAN GIOVANINI DE OLIVEIRA SARTORI, ESALQ; FERNANDA FRANCETTO JULIANO, ESALQ; JOSÉ EDUARDO PEDROSO GOMES DO AMARAL, ESALQ; ROSEANE CAVALCANTI DOS SANTOS, CNPA; LIZIANE MARIA DE LIMA, CNPA; SEVERINO MATIAS DE ALENCAR, ESALQ. |
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Título: |
Simulated gastrointestinal digestion/Caco-2 cell model to predict bioaccessibility and intestinal permeability of p-coumaric acid and p-coumaroyl derivatives in peanut. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
Food Chemistry, v. 400, 134036, p. 1-8, 2023. |
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ISSN: |
2590-1575 |
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Idioma: |
Inglês |
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Conteúdo: |
Data concerning physiological recovery of whole peanut major phenolics throughout the gastrointestinal tract are scarce. In our study, the bioaccessibility and intestinal permeability of peanuts major phenolics were predicted by simulated digestion followed by Caco-2 cells monolayer model. Phenolics identification and quantification were performed by HPLC-ESI-QTOF-MS and HPLC-PDA, respectively. As results, p-coumaroyl conjugates with tartaric, sinapic and ferulic acids, and p-coumaric acid were the major phenolics found in the non-digested extract and in the digested and transported fractions. The in vitro bioaccessibility and Caco-2 cell transport of pcoumaric acid was 370% and 127%, respectively, while it was much lower for p-coumaroyl derivatives (7-100% and 14-31%, respectively). Nonetheless, the peroxyl scavenging activity remained unaltered, likely, at least artly, due to synergies between some phenolics, which concentration proportions changed throughout the experiment. Hence, there is indication that whole peanut is a source of bioavailable antioxidant phenolics. |
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Thesagro: |
Amendoim; Nutrição Humana; Óleo Vegetal; Proteína Vegetal. |
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Thesaurus NAL: |
Arid zones; Peanuts; Phenolic compounds. |
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Categoria do assunto: |
Q Alimentos e Nutrição Humana |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1152824/1/SIMULATED-GASTROINTESTINAL-DIGESTION.pdf
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Marc: |
LEADER 01992naa a2200289 a 4500
001 2152824
005 2023-03-28
008 2023 bl uuuu u00u1 u #d
022 $a2590-1575
100 1 $aMASSARIOLI, A. P.
245 $aSimulated gastrointestinal digestion/Caco-2 cell model to predict bioaccessibility and intestinal permeability of p-coumaric acid and p-coumaroyl derivatives in peanut.$h[electronic resource]
260 $c2023
520 $aData concerning physiological recovery of whole peanut major phenolics throughout the gastrointestinal tract are scarce. In our study, the bioaccessibility and intestinal permeability of peanuts major phenolics were predicted by simulated digestion followed by Caco-2 cells monolayer model. Phenolics identification and quantification were performed by HPLC-ESI-QTOF-MS and HPLC-PDA, respectively. As results, p-coumaroyl conjugates with tartaric, sinapic and ferulic acids, and p-coumaric acid were the major phenolics found in the non-digested extract and in the digested and transported fractions. The in vitro bioaccessibility and Caco-2 cell transport of pcoumaric acid was 370% and 127%, respectively, while it was much lower for p-coumaroyl derivatives (7-100% and 14-31%, respectively). Nonetheless, the peroxyl scavenging activity remained unaltered, likely, at least artly, due to synergies between some phenolics, which concentration proportions changed throughout the experiment. Hence, there is indication that whole peanut is a source of bioavailable antioxidant phenolics.
650 $aArid zones
650 $aPeanuts
650 $aPhenolic compounds
650 $aAmendoim
650 $aNutrição Humana
650 $aÓleo Vegetal
650 $aProteína Vegetal
700 1 $aSARTORI, A. G. de O.
700 1 $aJULIANO, F. F.
700 1 $aAMARAL, J. E. P. G. do
700 1 $aSANTOS, R. C. dos
700 1 $aLIMA, L. M. de
700 1 $aALENCAR, S. M. de
773 $tFood Chemistry$gv. 400, 134036, p. 1-8, 2023.
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Registro original: |
Embrapa Algodão (CNPA) |
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