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Registro Completo |
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
09/01/2020 |
Data da última atualização: |
06/02/2024 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
OTTO, P. I.; GUIMARÃES, S. E. F.; VERARDO, L. L.; AZEVEDO, A. L. S.; VANDENPLAS, J.; SEVILLANO, C. A.; MARQUES, D. B. D.; PIRES, M. de F. A.; FREITAS, C. de; VERNEQUE, R. da S.; MARTINS, M. F.; PANETTO, J. C. do C.; CARVALHO, W. A.; GOBO, D. O. R.; SILVA, M. V. G. B.; MACHADO, M. A. |
Afiliação: |
ANA LUISA SOUSA AZEVEDO, CNPGL; MARIA DE FATIMA AVILA PIRES, CNPGL; CELIO DE FREITAS, CNPGL; RUI DA SILVA VERNEQUE, CNPGL; MARTA FONSECA MARTINS, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; WANESSA ARAUJO CARVALHO, CNPGL; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; MARCO ANTONIO MACHADO, CNPGL. |
Título: |
Genome-wide association studies for heat stress response in Bos taurus × Bos indicus crossbred cattle. |
Ano de publicação: |
2019 |
Fonte/Imprenta: |
Journal of Dairy Science, v. 102, n. 9, p. 8148-8158, 2019. |
DOI: |
https://doi.org/10.3168/jds.2018-15305 |
Idioma: |
Inglês |
Conteúdo: |
Heat stress is an important issue in the global dairy industry. In tropical areas, an alternative to overcome heat stress is the use of crossbred animals or synthetic breeds, such as the Girolando. In this study, we performed a genome-wide association study (GWAS) and post-GWAS analyses for heat stress in an experimental Gir × Holstein F2 population. Rectal temperature (RT) was measured in heat-stressed F2 animals, and the variation between 2 consecutive RT measurements (ΔRT) was used as the dependent variable. Illumina BovineSNP50v1 BeadChip (Illumina Inc., San Diego, CA) and single-SNP approach were used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene-transcription factor (TF) networks, generated from enriched TF. The breed origin of marker alleles in the F2 population was assigned using the breed of origin of alleles (BOA) approach. Heritability and repeatability estimates (± standard error) for ΔRT were 0.13 ± 0.08 and 0.29 ± 0.06, respectively. Association analysis revealed 6 SNP significantly associated with ΔRT. Genes involved with biological processes in response to heat stress effects (LIF, OSM, TXNRD2, and DGCR8) were identified as putative candidate genes. After performing the BOA approach, the 10% of F2 animals with the lowest breeding values for ΔRT were classified as low-ΔRT, and the 10% with the highest breeding values for ΔRT were classified as high-ΔRT. On average, 49.4% of low-ΔRT animals had 2 alleles from the Holstein breed (HH), and 39% had both alleles from the Gir breed (GG). In high-ΔRT animals, the average proportion of animals for HH and GG were 1.4 and 50.2%, respectively. This study allowed the identification of candidate genes for ΔRT in Gir × Holstein crossbred animals. According to the BOA approach, Holstein breed alleles could be associated with better response to heat stress effects, which could be explained by the fact that Holstein animals are more affected by heat stress than Gir animals and thus require a genetic architecture to defend the body from the deleterious effects of heat stress. Future studies can provide further knowledge to uncover the genetic architecture underlying heat stress in crossbred cattle. MenosHeat stress is an important issue in the global dairy industry. In tropical areas, an alternative to overcome heat stress is the use of crossbred animals or synthetic breeds, such as the Girolando. In this study, we performed a genome-wide association study (GWAS) and post-GWAS analyses for heat stress in an experimental Gir × Holstein F2 population. Rectal temperature (RT) was measured in heat-stressed F2 animals, and the variation between 2 consecutive RT measurements (ΔRT) was used as the dependent variable. Illumina BovineSNP50v1 BeadChip (Illumina Inc., San Diego, CA) and single-SNP approach were used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene-transcription factor (TF) networks, generated from enriched TF. The breed origin of marker alleles in the F2 population was assigned using the breed of origin of alleles (BOA) approach. Heritability and repeatability estimates (± standard error) for ΔRT were 0.13 ± 0.08 and 0.29 ± 0.06, respectively. Association analysis revealed 6 SNP significantly associated with ΔRT. Genes involved with biological processes in response to heat stress effects (LIF, OSM, TXNRD2, and DGCR8) were identified as putative candidate genes. After performing the BOA approach, the 10% of F2 animals with the lowest breeding values for ΔRT were classified as low-ΔRT, and the 10% with the highest breeding values for ΔRT were classified as high-ΔRT. On average, 49.4% of low-ΔR... Mostrar Tudo |
Palavras-Chave: |
Crossbred cattle; Gene network; Post-GWAS analyses. |
Thesaurus Nal: |
Heat stress. |
Categoria do assunto: |
-- |
Marc: |
LEADER 03369naa a2200361 a 4500 001 2118465 005 2024-02-06 008 2019 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.3168/jds.2018-15305$2DOI 100 1 $aOTTO, P. I. 245 $aGenome-wide association studies for heat stress response in Bos taurus × Bos indicus crossbred cattle.$h[electronic resource] 260 $c2019 520 $aHeat stress is an important issue in the global dairy industry. In tropical areas, an alternative to overcome heat stress is the use of crossbred animals or synthetic breeds, such as the Girolando. In this study, we performed a genome-wide association study (GWAS) and post-GWAS analyses for heat stress in an experimental Gir × Holstein F2 population. Rectal temperature (RT) was measured in heat-stressed F2 animals, and the variation between 2 consecutive RT measurements (ΔRT) was used as the dependent variable. Illumina BovineSNP50v1 BeadChip (Illumina Inc., San Diego, CA) and single-SNP approach were used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene-transcription factor (TF) networks, generated from enriched TF. The breed origin of marker alleles in the F2 population was assigned using the breed of origin of alleles (BOA) approach. Heritability and repeatability estimates (± standard error) for ΔRT were 0.13 ± 0.08 and 0.29 ± 0.06, respectively. Association analysis revealed 6 SNP significantly associated with ΔRT. Genes involved with biological processes in response to heat stress effects (LIF, OSM, TXNRD2, and DGCR8) were identified as putative candidate genes. After performing the BOA approach, the 10% of F2 animals with the lowest breeding values for ΔRT were classified as low-ΔRT, and the 10% with the highest breeding values for ΔRT were classified as high-ΔRT. On average, 49.4% of low-ΔRT animals had 2 alleles from the Holstein breed (HH), and 39% had both alleles from the Gir breed (GG). In high-ΔRT animals, the average proportion of animals for HH and GG were 1.4 and 50.2%, respectively. This study allowed the identification of candidate genes for ΔRT in Gir × Holstein crossbred animals. According to the BOA approach, Holstein breed alleles could be associated with better response to heat stress effects, which could be explained by the fact that Holstein animals are more affected by heat stress than Gir animals and thus require a genetic architecture to defend the body from the deleterious effects of heat stress. Future studies can provide further knowledge to uncover the genetic architecture underlying heat stress in crossbred cattle. 650 $aHeat stress 653 $aCrossbred cattle 653 $aGene network 653 $aPost-GWAS analyses 700 1 $aGUIMARÃES, S. E. F. 700 1 $aVERARDO, L. L. 700 1 $aAZEVEDO, A. L. S. 700 1 $aVANDENPLAS, J. 700 1 $aSEVILLANO, C. A. 700 1 $aMARQUES, D. B. D. 700 1 $aPIRES, M. de F. A. 700 1 $aFREITAS, C. de 700 1 $aVERNEQUE, R. da S. 700 1 $aMARTINS, M. F. 700 1 $aPANETTO, J. C. do C. 700 1 $aCARVALHO, W. A. 700 1 $aGOBO, D. O. R. 700 1 $aSILVA, M. V. G. B. 700 1 $aMACHADO, M. A. 773 $tJournal of Dairy Science$gv. 102, n. 9, p. 8148-8158, 2019.
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Embrapa Gado de Leite (CNPGL) |
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Biblioteca(s): |
Embrapa Florestas. |
Data corrente: |
15/10/2021 |
Data da última atualização: |
18/10/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 3 |
Autoria: |
SANTOS, A. T. dos; DOMENE, V. D.; MATTOS, P. P. de; BRAZ, E. M.; CANETTI, A.; NAKAJIMA, N. Y.; ROSOT, N. C. |
Afiliação: |
ANDREIA TABORDA DOS SANTOS, UFPR; VITOR DRESSANO DOMENE, Mademape Indústria Madeireira Ltda; PATRICIA POVOA DE MATTOS, CNPF; EVALDO MUNOZ BRAZ, CNPF; ALINE CANETTI, Consultora autônoma; NELSON YOSHIHIRO NAKAJIMA, UFPR; NELSON CARLOS ROSOT, UFPR. |
Título: |
Equação de volume para espécies de Cerrado em Formosa, GO. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Pesquisa Florestal Brasileira, Colombo, v. 41, e201902075, 2021. 8 p. |
DOI: |
https://doi.org/10.4336/2021.pfb.41e201902075 |
Idioma: |
Português |
Conteúdo: |
O presente trabalho teve como objetivo ajustar modelos para a estimativa de volume de espécies do Cerrado, em Formosa, GO. Foram selecionados de 12 a 15 indivíduos de nove espécies, representando a amplitude das classes diamétricas de cada espécie, na área de estudo. As árvores foram derrubadas e mensuradas por cubagem rigorosa e seus volumes foram calculados pelo método de Smalian. Foram testados sete modelos matemáticos para a estimativa do volume por espécie e total, sendo que o melhor modelo foi selecionado com base nos parâmetros estatísticos: coeficiente de determinação ajustado, erro padrão da estimativa e distribuição gráfica dos resíduos. Os modelos de Hohenadl-Krenn, de simples entrada, e Naslund modificado, de dupla entrada, apresentaram os melhores ajustes para a estimativa de volume de árvore individual das nove espécies estudadas e de todo conjunto de espécies. |
Palavras-Chave: |
Hohenadl-Krenn; Modelagem; Modelling; Naslund modificado. |
Categoria do assunto: |
K Ciência Florestal e Produtos de Origem Vegetal |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/226999/1/Santos-2075-Texto-do-artigo-22208-1-10-20210930.pdf
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Marc: |
LEADER 01655naa a2200253 a 4500 001 2135386 005 2021-10-18 008 2021 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.4336/2021.pfb.41e201902075$2DOI 100 1 $aSANTOS, A. T. dos 245 $aEquação de volume para espécies de Cerrado em Formosa, GO.$h[electronic resource] 260 $c2021 520 $aO presente trabalho teve como objetivo ajustar modelos para a estimativa de volume de espécies do Cerrado, em Formosa, GO. Foram selecionados de 12 a 15 indivíduos de nove espécies, representando a amplitude das classes diamétricas de cada espécie, na área de estudo. As árvores foram derrubadas e mensuradas por cubagem rigorosa e seus volumes foram calculados pelo método de Smalian. Foram testados sete modelos matemáticos para a estimativa do volume por espécie e total, sendo que o melhor modelo foi selecionado com base nos parâmetros estatísticos: coeficiente de determinação ajustado, erro padrão da estimativa e distribuição gráfica dos resíduos. Os modelos de Hohenadl-Krenn, de simples entrada, e Naslund modificado, de dupla entrada, apresentaram os melhores ajustes para a estimativa de volume de árvore individual das nove espécies estudadas e de todo conjunto de espécies. 653 $aHohenadl-Krenn 653 $aModelagem 653 $aModelling 653 $aNaslund modificado 700 1 $aDOMENE, V. D. 700 1 $aMATTOS, P. P. de 700 1 $aBRAZ, E. M. 700 1 $aCANETTI, A. 700 1 $aNAKAJIMA, N. Y. 700 1 $aROSOT, N. C. 773 $tPesquisa Florestal Brasileira, Colombo$gv. 41, e201902075, 2021. 8 p.
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