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Registros recuperados : 27 | |
10. | | FUKUSHIMA, R. S.; ROSA, A. J. de M.; LIMA, C. G. de; CUNHA, J. A. da. Comparação entre dois métodos analíticos para determinação da lignina de algumas gramíneas forrageiras. Pesquisa Agropecuária Brasileira, Brasília, DF, v. 34, n. 6, p. 1025-30, jun. 1999 Título em inglês: Comparison between two analytical methods for determining lignin concentration of some grass forages. Biblioteca(s): Embrapa Unidades Centrais. |
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12. | | GEORGE, S.; CIRCLE, K.; LINDBLOM, S.; VILAIN, S.; ROSA, A. J. de M.; FRANCIS, D.; BRÖZEL, V.; KAUSHIK, R. S. Assessment of toll-like receptors in the ileum of weanling pigs - responses to feed antibiotic chlortetracycline and gnotobiotic conditions. Journal of Clinical & Cellular Immunology, v. 3, issue 3, 2012. Biblioteca(s): Embrapa Cerrados. |
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13. | | DUARTE, I. de A. E.; MILENKOVIC, D.; BORGES, T. K. dos S.; ROSA, A. J. de M.; MORAND, C.; OLIVEIRA, L. de L. de; COSTA, A. M. Acute Effects of the Consumption of Passiflora setacea Juice on Metabolic Risk Factors and Gene Expression Profile in Humans Nutrients, v. 12, n. 1104, 2020. 20 p. Biblioteca(s): Embrapa Cerrados. |
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14. | | RETTEDAL, E.; VILAIN, S.; LINDBLOM, S.; LEHNERT, K.; SCOFIELD, C.; GEORGE, S.; CLAY, S.; KAUSHIK, R. S.; ROSA, A. J. de M.; FRANCIS, D.; BRÖZEL, V. S. Alteration of the ileal microbiota of weanling piglets by the growth-promoting antibiotic chlortetracycline. Applied and Environmental Microbiology, v. 75, n. 17, p. 5489-5495, sept. 2009. Biblioteca(s): Embrapa Cerrados. |
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16. | | MOREIRA, J. R.; BALESTRA, R. A. N.; FREITAS, F. O.; LUSTOSA, A. P. G.; ROSA, A. J. de M.; SAMPAIO, A. A.; FERREIRA JÚNIOR, P. D. Podocnemis expansa (Giant South American River Turtle) nesting range expansion. Herpetological Review, v. 42, n. 4, p. 595-596, 2011. Biblioteca(s): Embrapa Cerrados; Embrapa Recursos Genéticos e Biotecnologia. |
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17. | | OKINO, C. H.; ALESSI, A. C.; MONTASSIER, M. de F. S.; ROSA, A. J. de M.; WANG, X.; MONTASSIER, H. J. Humoral and Cell-Mediated Immune Responses to Different Doses of Attenuated Vaccine Against Avian Infectious Bronchitis Virus. Viral Immunology, Nova York, v. 26, n. 4, p. 1-9, 2013. Biblioteca(s): Embrapa Cerrados; Embrapa Suínos e Aves. |
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18. | | CASTRO, L. M. de; ROSA, G. J. de M.; LOPES, F. B.; REGITANO, L. C. de A.; ROSA, A. J. de M.; MAGNABOSCO, C. de U. Genomewide association mapping and pathway analysis of meat tenderness in Polled Nellore cattle. Journal of Animal Science, v. 95, n. 5, p. 1945-1956, 2017. Biblioteca(s): Embrapa Cerrados; Embrapa Pecuária Sudeste. |
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19. | | SILVA, M. S. G. M. e; RUOCCO, A. M. C.; RODRIGUES, G. S.; ROSA, A. J. de M.; PORTINHO, J. L. Índice multiatributo para métricas de biodiversidade bentônica em áreas de aquicultura: ensaios em reservatórios do sudeste brasileiro. In: CONGRESSO BRASILEIRO DE AQUICULTURA E BIOLOGIA AQUÁTICA, 10., 2023, Florianópolis. Anais eletrônicos... Florianópolis: UFSC, Aquabio, 2023. Biblioteca(s): Embrapa Meio Ambiente. |
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20. | | ROSA, A. J. de M.; PACKER, I. U.; REGITANO, L. C. de A.; RAZOOK, A.; FIGUEIREDO, L. G.; COUTINHO, L. L. Caracterização da raça Nelore e teste de paternidade e por marcadores moleculares. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 34., 1997, Juiz de Fora. Anais... Juiz de Fora: SBZ, 1997. p.62-64. Biblioteca(s): Embrapa Pecuária Sudeste. |
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Registros recuperados : 27 | |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Cerrados. Para informações adicionais entre em contato com cpac.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Cerrados. |
Data corrente: |
26/07/2011 |
Data da última atualização: |
05/12/2012 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 1 |
Autoria: |
SARDINA, M. T.; ROSA, A. J. de M.; DAVOLI, R.; BRAGLIA, S.; PORTOLANO, B. |
Afiliação: |
M. T. SARDINA, UNIVERSITY OF PALERMO; ARTUR JORDAO DE MAGALHAES ROSA, CPAC; R. DAVOLI, UNIVERSITY OF BOLOGNA; S. BRAGLIA, UNIVERSITY OF BOLOGNA; B. PORTOLANO, UNIVERSITY OF PALERMO. |
Título: |
Polymorphisms of beta-lactoglobulin promoter region in three sicilian goat breeds. |
Ano de publicação: |
2012 |
Fonte/Imprenta: |
Molecular Biology Reports, v. 39, n. 3, 2012. |
Idioma: |
Inglês |
Conteúdo: |
Several beta-lactoglobulin (BLG) polymorphisms have been described within the proximal promoter region and coding region of the caprine gene, although no genetic variants affecting the protein amino acid composition and/or expression level have been characterized so far. Binding sites for several transcription factors (TFs) are present in the BLG promoter region. The aims of this work were to sequence the full-length promoter region of three Sicilian goat breeds in order to identify polymorphisms, analyze the identified haplotypes, search for differences between breeds for the presence of polymorphisms in this gene region, search for putative TFs binding sites, and check if polymorphisms lay within the identified TFs binding sites. The promoter region of BLG gene in Sicilian goat breeds showed high level of polymorphism due to the presence of 36 single nucleotide polymorphisms (SNPs). Association between polymorphic sites was computed within the whole sample analyzed and 18 haplotypes were inferred. Binding sites for three milk protein binding factors (MPBFs) and four nuclear factor-I (NF-I) were found within BLG promoter region based on the ovine sequence. The identification of some SNPs within TFs binding sites allowed hypothesizing the loss of TFs. Further studies are in progress to evaluate the effect of these mutations on binding affinity of TFs, the functional interaction of the TFs with the goat BLG promoter, and the relationship of the polymorphisms with BLG gene expression and milk production and composition. MenosSeveral beta-lactoglobulin (BLG) polymorphisms have been described within the proximal promoter region and coding region of the caprine gene, although no genetic variants affecting the protein amino acid composition and/or expression level have been characterized so far. Binding sites for several transcription factors (TFs) are present in the BLG promoter region. The aims of this work were to sequence the full-length promoter region of three Sicilian goat breeds in order to identify polymorphisms, analyze the identified haplotypes, search for differences between breeds for the presence of polymorphisms in this gene region, search for putative TFs binding sites, and check if polymorphisms lay within the identified TFs binding sites. The promoter region of BLG gene in Sicilian goat breeds showed high level of polymorphism due to the presence of 36 single nucleotide polymorphisms (SNPs). Association between polymorphic sites was computed within the whole sample analyzed and 18 haplotypes were inferred. Binding sites for three milk protein binding factors (MPBFs) and four nuclear factor-I (NF-I) were found within BLG promoter region based on the ovine sequence. The identification of some SNPs within TFs binding sites allowed hypothesizing the loss of TFs. Further studies are in progress to evaluate the effect of these mutations on binding affinity of TFs, the functional interaction of the TFs with the goat BLG promoter, and the relationship of the polymorphisms with BLG gene exp... Mostrar Tudo |
Palavras-Chave: |
Beta lactoglobulina. |
Thesagro: |
Genética; Polimorfismo. |
Categoria do assunto: |
-- |
Marc: |
LEADER 02105naa a2200205 a 4500 001 1896808 005 2012-12-05 008 2012 bl uuuu u00u1 u #d 100 1 $aSARDINA, M. T. 245 $aPolymorphisms of beta-lactoglobulin promoter region in three sicilian goat breeds. 260 $c2012 520 $aSeveral beta-lactoglobulin (BLG) polymorphisms have been described within the proximal promoter region and coding region of the caprine gene, although no genetic variants affecting the protein amino acid composition and/or expression level have been characterized so far. Binding sites for several transcription factors (TFs) are present in the BLG promoter region. The aims of this work were to sequence the full-length promoter region of three Sicilian goat breeds in order to identify polymorphisms, analyze the identified haplotypes, search for differences between breeds for the presence of polymorphisms in this gene region, search for putative TFs binding sites, and check if polymorphisms lay within the identified TFs binding sites. The promoter region of BLG gene in Sicilian goat breeds showed high level of polymorphism due to the presence of 36 single nucleotide polymorphisms (SNPs). Association between polymorphic sites was computed within the whole sample analyzed and 18 haplotypes were inferred. Binding sites for three milk protein binding factors (MPBFs) and four nuclear factor-I (NF-I) were found within BLG promoter region based on the ovine sequence. The identification of some SNPs within TFs binding sites allowed hypothesizing the loss of TFs. Further studies are in progress to evaluate the effect of these mutations on binding affinity of TFs, the functional interaction of the TFs with the goat BLG promoter, and the relationship of the polymorphisms with BLG gene expression and milk production and composition. 650 $aGenética 650 $aPolimorfismo 653 $aBeta lactoglobulina 700 1 $aROSA, A. J. de M. 700 1 $aDAVOLI, R. 700 1 $aBRAGLIA, S. 700 1 $aPORTOLANO, B. 773 $tMolecular Biology Reports$gv. 39, n. 3, 2012.
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