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 | Acesso ao texto completo restrito à biblioteca da Embrapa Amapá. Para informações adicionais entre em contato com cpafap.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Amapá. |
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Data corrente: |
03/10/2011 |
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Data da última atualização: |
28/11/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
PAMPLONA, J. H.; OBA, E. T.; SILVA, T. A.; RAMOS, L. P.; RAMSDORF, W. A.; CESTARI, M. M.; RIBEIRO, C. A. O.; ZAMPRONIO, A. R.; ASSIS, H. C. S. de. |
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Afiliação: |
J.H. PAMPLONA, UFPR; ELIANE TIE OBA YOSHIOKA, CPAF-AP; T.A. DA SILVA, UFPR; L. P. RAMOS, UFPR; W. A. RAMSDORF, UFPR; M. M. CESTARI, UFPR; C. A. O. RIBEIRO, UFPR; A. R. ZAMPRONIO, UFPR; H. C. S. DE ASSIS, UFPR. |
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Título: |
Subchronic effects of dipyrone on the fish species Rhamdia quelen. |
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Ano de publicação: |
2011 |
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Fonte/Imprenta: |
Ecotoxicology and Environmental Safety, v. 74, n. 3, p. 342-349, Mar. 2011. |
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Idioma: |
Inglês |
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Conteúdo: |
The use of the non-steroidal anti-inflammatory drugs such as dipyrone is so widespread that this drug and its metabolites have been detected in effluents and surface water. This study aimed to evaluate the potential toxic effects of dipyrone on the aquatic environment, using a native fish species, Rhamdia quelen. Fish were exposed to three concentrations of dipyrone, 0.5, 5 and 50 mg/L, in the water for 15 days, and hematological, biochemical, genetic and morphological biomarkers were evaluated. The glutathione S-transferase activity decreased in the highest concentration in relation to the control group. In addition, hematocrit, red blood cells and thrombocyte counts were decreased in all three exposed groups in relation to the control group. The comet assay showed DNA damage at the lowest concentration of dipyrone and significant kidney damage. Those results suggest that a constant exposure of aquatic organisms to dipyrone presents potential toxic effects. |
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Thesagro: |
Bagre; Peixe de água doce. |
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Categoria do assunto: |
S Ciências Biológicas |
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Marc: |
LEADER 01670naa a2200241 a 4500
001 1902083
005 2017-11-28
008 2011 bl uuuu u00u1 u #d
100 1 $aPAMPLONA, J. H.
245 $aSubchronic effects of dipyrone on the fish species Rhamdia quelen.$h[electronic resource]
260 $c2011
520 $aThe use of the non-steroidal anti-inflammatory drugs such as dipyrone is so widespread that this drug and its metabolites have been detected in effluents and surface water. This study aimed to evaluate the potential toxic effects of dipyrone on the aquatic environment, using a native fish species, Rhamdia quelen. Fish were exposed to three concentrations of dipyrone, 0.5, 5 and 50 mg/L, in the water for 15 days, and hematological, biochemical, genetic and morphological biomarkers were evaluated. The glutathione S-transferase activity decreased in the highest concentration in relation to the control group. In addition, hematocrit, red blood cells and thrombocyte counts were decreased in all three exposed groups in relation to the control group. The comet assay showed DNA damage at the lowest concentration of dipyrone and significant kidney damage. Those results suggest that a constant exposure of aquatic organisms to dipyrone presents potential toxic effects.
650 $aBagre
650 $aPeixe de água doce
700 1 $aOBA, E. T.
700 1 $aSILVA, T. A.
700 1 $aRAMOS, L. P.
700 1 $aRAMSDORF, W. A.
700 1 $aCESTARI, M. M.
700 1 $aRIBEIRO, C. A. O.
700 1 $aZAMPRONIO, A. R.
700 1 $aASSIS, H. C. S. de
773 $tEcotoxicology and Environmental Safety$gv. 74, n. 3, p. 342-349, Mar. 2011.
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Embrapa Amapá (CPAF-AP) |
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| Registros recuperados : 3 | |
| 1. |  | COSTA, C.; PEDROSO, B. A.; EICHLER, L.; FONTANELI, R. S.; RICHTER, L. A.; ZINN, D. M.; MATTIA, L. R. Comportamento de genótipos de aveia em várzea. Lavoura Arrozeira, Porto Alegre, v. 44, n. 397, p. 38-39, jul./ago. 1991. EXPOINTER.| Biblioteca(s): Embrapa Trigo. |
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| 2. | | COSTA, C.; RICHTER, L. A.; ZINN, D. M.; EICHLER, L.; FONTANELI, R. S.; PEDROSO, B. A.; SCIPIONI, C.; MIOLA, G. Resposta da cultivar de aveia UPF 12 (Avena sativa L.) a duração e período de inundação do solo. In: CONGRESSO BRASILEIRO DE ENGENHARIA AGRÍCOLA, 20., 1991, Londrina. Anais... [Londrina]: SBEA / IAPAR, [1992]. v. 1 p. 540-548| Biblioteca(s): Embrapa Trigo. |
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| 3. | | COSTA, C.; RICHTER, L. A.; ZINN, D. M.; EICHLER, L.; FONTANELI, R. S.; PEDROSO, B. A.; SCIPIONI, C.; MIOLA, G. Influência da profundidade do lençol freático sobre a produção de matéria verde e seca de genótipos de aveia. In: CONGRESSO BRASILEIRO DE ENGENHARIA AGRÍCOLA, 20., 1991, Londrina. Anais... [Londrina]: SBEA / IAPAR, [1992]. v. 1 p. 549-558| Biblioteca(s): Embrapa Trigo. |
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| Registros recuperados : 3 | |
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