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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
11/12/2019 |
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Data da última atualização: |
11/12/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
BILHASSI, T. B.; GIGLIOTI, R.; OKINO, C. H.; MALAGO JUNIOR, W.; OLIVEIRA, H. N. de; MARCONDES, C. R.; OLIVEIRA, M. C. de S. |
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Afiliação: |
Talita Barban Bilhassi, UNESP; Rodrigo Giglioti, UNESP; CINTIA HIROMI OKINO, CPPSE; WILSON MALAGO JUNIOR, CPPSE; Henrique Nunes de Oliveira, UNESP; CINTIA RIGHETTI MARCONDES, CPPSE; MARCIA CRISTINA DE SENA OLIVEIRA, CPPSE. |
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Título: |
Differential IL10 mRNA profiles associated to Babesia bovis and B. bigemina infection levels in persistently infected animals. |
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Ano de publicação: |
2019 |
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Fonte/Imprenta: |
Open Journal of Veterinary Medicine, v. 9, p.161-169, 2019 |
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DOI: |
10.4236/ojvm.2019.911014 |
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Idioma: |
Inglês |
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Conteúdo: |
This work aimed to find quantitative phenotypic traits that can be used to discriminate the levels of resistance/susceptibility to B. bovis and B. bigemina in two groups of cattle presenting the highest (H) or lowest (L) infection levels and Rhipicephalus microplus ticks count. The animals were selected from a previous study of 50 Canchim (5/8 Charolais/zebu) heifers raised in an endemic area for these parasites. These animals were evaluated regarding their TNFα, IL10, IFN-γ, IL12 and iNOS mRNA levels. No differences were found between these groups regarding TNFα, IFN-γ, IL12β or iNOS transcripts. However, the IL10 transcripts were significantly higher in the H group compared to the L group. Moreover, significant correlation coefficients were observed between B. bovis loads and both IL10 and IFN-γ transcripts, while no correlations were found for B. bigemina loads and all tested immune-related transcripts, suggesting that differential IL10 mRNA profiles were closely associated to B. bovis loads. Our results have contributed to a better understanding of the immune responses against Babesia infection, as we demonstrated that the IL10 cytokine levels might also influence or be influenced by parasitemia levels in persistently infected animals |
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Palavras-Chave: |
RT-qPCR; Tick. |
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Thesagro: |
Carrapato. |
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Thesaurus Nal: |
Animal parasites and pests; Cytokines; Gene expression; Parasites; Rhipicephalus microplus; Ticks. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02225naa a2200313 a 4500
001 2116598
005 2019-12-11
008 2019 bl uuuu u00u1 u #d
024 7 $a10.4236/ojvm.2019.911014$2DOI
100 1 $aBILHASSI, T. B.
245 $aDifferential IL10 mRNA profiles associated to Babesia bovis and B. bigemina infection levels in persistently infected animals.$h[electronic resource]
260 $c2019
520 $aThis work aimed to find quantitative phenotypic traits that can be used to discriminate the levels of resistance/susceptibility to B. bovis and B. bigemina in two groups of cattle presenting the highest (H) or lowest (L) infection levels and Rhipicephalus microplus ticks count. The animals were selected from a previous study of 50 Canchim (5/8 Charolais/zebu) heifers raised in an endemic area for these parasites. These animals were evaluated regarding their TNFα, IL10, IFN-γ, IL12 and iNOS mRNA levels. No differences were found between these groups regarding TNFα, IFN-γ, IL12β or iNOS transcripts. However, the IL10 transcripts were significantly higher in the H group compared to the L group. Moreover, significant correlation coefficients were observed between B. bovis loads and both IL10 and IFN-γ transcripts, while no correlations were found for B. bigemina loads and all tested immune-related transcripts, suggesting that differential IL10 mRNA profiles were closely associated to B. bovis loads. Our results have contributed to a better understanding of the immune responses against Babesia infection, as we demonstrated that the IL10 cytokine levels might also influence or be influenced by parasitemia levels in persistently infected animals
650 $aAnimal parasites and pests
650 $aCytokines
650 $aGene expression
650 $aParasites
650 $aRhipicephalus microplus
650 $aTicks
650 $aCarrapato
653 $aRT-qPCR
653 $aTick
700 1 $aGIGLIOTI, R.
700 1 $aOKINO, C. H.
700 1 $aMALAGO JUNIOR, W.
700 1 $aOLIVEIRA, H. N. de
700 1 $aMARCONDES, C. R.
700 1 $aOLIVEIRA, M. C. de S.
773 $tOpen Journal of Veterinary Medicine$gv. 9, p.161-169, 2019
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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| Registros recuperados : 258 | |
| 1. |  | RAMOS, N. P. Agroenergia. In: HAMMES, V. S. (Ed.). Ver: percepção do diagnóstico ambiental. 3. ed. rev. e ampl. Brasília, DF: Embrapa, 2012. v. 3, pt. 1 , p. 43-56 . (Educação Ambiental para o Desenvolvimento Sustentável, v. 3).| Tipo: Capítulo em Livro Técnico-Científico |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 9. | | BATISTA, E. R.; RAMOS, N. P.; LUCHIARI JUNIOR, A. Bioeletricidade, mercado de carbono e o setor sucroalcooleiro paulista. In: STAB: Açúcar, álcool e subprodutos, v.27, n.2, p.32, 2008. Reumos do 9. Congresso Nacional da STAB, 2008, Maceió.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| 15. | | RAMOS, N. P.; DELGADO JUNIOR, J. P.; LUCHIARI JUNIOR, A. Expansão do girassol no Brasil: monitoramento de tendências. In: REUNIÃO NACIONAL DE PESQUISA DO GIRASSOL, 18.; SIMPÓSIO NACIONAL SOBRE A CULTURA DO GIRASSOL, 6., 2009, Pelotas. Anais... Pelotas: Embrapa Clima Temperado, 2009. Editado por Ana Paula Schneid Afonso Rosa, Márcia Vizzotto, Simone Ery Grosskopf. p. 37-43.| Tipo: Artigo em Anais de Congresso |
| Biblioteca(s): Embrapa Meio Ambiente. |
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| Registros recuperados : 258 | |
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