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Registro Completo |
Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
Data corrente: |
16/10/2015 |
Data da última atualização: |
16/03/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
VIANA, J. F. C.; CARRIJO, J.; FREITAS, C. G.; PAUL, A.; ALCARAZ, J.; LACORTE, C. C.; MIGLIOLO, L.; ANDRADE, C. A.; FALCAO, R.; SANTOS, N. C.; GONÇALVES, S.; OTERO-GONZÁLES, A. J.; KHADEMHOSSEINI, A.; DIAS, S. C.; FRANCO, O. L. |
Afiliação: |
Juliane F. C. Viana, UnB; Jéssica Carrijo, UCB; Camila G. Freitas, UCB; Arghya Paul, Massachusetts Institute of Technology, Cambridge, USA; Jarib Alcaraz, Universidade Federal de Pernambuco; CRISTIANO CASTRO LACORTE, CENARGEN; Ludovico Migliolo, UCB; César A. Andrade, Universidade Federal de Pernambuco; ROSANA FALCAO, CENARGEN; Nuno C. Santos, Universidade de Lisboa; Sónia Gonçalves, Universidade de Lisboa; Anselmo J. Otero-González, Universidad de La Habana; Ali Khademhosseini, Massachusetts Institute of Technology, Cambridge, USA; Simoni C. Dias, UCB; Octávio L. Franco, UnB. |
Título: |
Antifungal nanofibers made by controlled release of sea animal derived peptide. |
Ano de publicação: |
2015 |
Fonte/Imprenta: |
Nanoscale, v. 7, p. 6238-6246, 2015. |
Idioma: |
Português |
Conteúdo: |
Candida albicans is a common human-pathogenic fungal species with the ability to cause several diseases including surface infections. Despite the clear difficulties of Candida control, antimicrobial peptides (AMPs) have emerged as an alternative strategy for fungal control. In this report, different concentrations of antifungal Cm-p1 (Cencritchis muricatus peptide 1) were electrospun into nanofibers for drug delivery. The nanofibers were characterized by mass spectrometry confirming the presence of the peptide on the scaffold. Atomic force microscopy and scanning electronic microscopy were used to measure the diameters, showing that Cm-p1 affects fiber morphology as well as the diameter and scaffold thickness. The Cm-p1 release behavior from the nanofibers demonstrated peptide release from 30 min to three days, leading to effective yeast control in the first 24 hours. Moreover, the biocompatibility of the fibers were evaluated through a MTS assay as well as ROS production by using a HUVEC model, showing that the fibers do not affect cell viability and only nanofibers containing 10% Cm-p1?PVA improved ROS generation. In addition, the secretion of pro-inflammatory cytokines IL-6 and TNF-? by the HUVECs was also slightly modified by the 10% Cm-p1?PVA nanofibers. In conclusion, the electrospinning technique applied here allowed for the manufacture of biodegradable biomimetic nanofibrous extracellular membranes with the ability to control fungal infection. |
Palavras-Chave: |
Controle de fungos; Fungos; Nanofibras. |
Thesagro: |
Cândida Albicans. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/156226/1/c5nr00767d.pdf
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Marc: |
LEADER 02381naa a2200337 a 4500 001 2026638 005 2023-03-16 008 2015 bl uuuu u00u1 u #d 100 1 $aVIANA, J. F. C. 245 $aAntifungal nanofibers made by controlled release of sea animal derived peptide.$h[electronic resource] 260 $c2015 520 $aCandida albicans is a common human-pathogenic fungal species with the ability to cause several diseases including surface infections. Despite the clear difficulties of Candida control, antimicrobial peptides (AMPs) have emerged as an alternative strategy for fungal control. In this report, different concentrations of antifungal Cm-p1 (Cencritchis muricatus peptide 1) were electrospun into nanofibers for drug delivery. The nanofibers were characterized by mass spectrometry confirming the presence of the peptide on the scaffold. Atomic force microscopy and scanning electronic microscopy were used to measure the diameters, showing that Cm-p1 affects fiber morphology as well as the diameter and scaffold thickness. The Cm-p1 release behavior from the nanofibers demonstrated peptide release from 30 min to three days, leading to effective yeast control in the first 24 hours. Moreover, the biocompatibility of the fibers were evaluated through a MTS assay as well as ROS production by using a HUVEC model, showing that the fibers do not affect cell viability and only nanofibers containing 10% Cm-p1?PVA improved ROS generation. In addition, the secretion of pro-inflammatory cytokines IL-6 and TNF-? by the HUVECs was also slightly modified by the 10% Cm-p1?PVA nanofibers. In conclusion, the electrospinning technique applied here allowed for the manufacture of biodegradable biomimetic nanofibrous extracellular membranes with the ability to control fungal infection. 650 $aCândida Albicans 653 $aControle de fungos 653 $aFungos 653 $aNanofibras 700 1 $aCARRIJO, J. 700 1 $aFREITAS, C. G. 700 1 $aPAUL, A. 700 1 $aALCARAZ, J. 700 1 $aLACORTE, C. C. 700 1 $aMIGLIOLO, L. 700 1 $aANDRADE, C. A. 700 1 $aFALCAO, R. 700 1 $aSANTOS, N. C. 700 1 $aGONÇALVES, S. 700 1 $aOTERO-GONZÁLES, A. J. 700 1 $aKHADEMHOSSEINI, A. 700 1 $aDIAS, S. C. 700 1 $aFRANCO, O. L. 773 $tNanoscale$gv. 7, p. 6238-6246, 2015.
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Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
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Registro Completo
Biblioteca(s): |
Embrapa Florestas. |
Data corrente: |
29/10/2020 |
Data da última atualização: |
29/10/2020 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
B - 1 |
Autoria: |
BURCKHARDT, D.; DALLE CORT, J.; QUEIROZ, D. L. de. |
Afiliação: |
Daniel Burckhardt, Naturhistorisches Museum; Giulia Dalle Cort, UFPR, CIFLOMA; DALVA LUIZ DE QUEIROZ, CNPF. |
Título: |
Jumping plant lice of the genus Aphalara (Hemiptera, Psylloidea, Aphalaridae) in the Neotropics. |
Ano de publicação: |
2020 |
Fonte/Imprenta: |
ZooKeys, v. 980, p. 119-140, 2020. |
DOI: |
10.3897/zookeys.980.56807 |
Idioma: |
Inglês |
Conteúdo: |
The Neotropical species of the predominantly north temperate genus Aphalara are reviewed. Four species are recorded here from this region, two of which are described as new. Aphalara ritteri sp. nov. occurs in southern Brazil (Paraná, Rio Grande do Sul, Santa Catarina) and represents the first and only species reported from South America. A second new species, Aphalara ortegae sp. nov., is described from Mexico and Puerto Rico. Another two species, Aphalara persicaria Caldwell, 1937 and A. simila Caldwell, 1937, have been previously reported from Mexico and the USA, and one of them also from Cuba. The two new species are both associated with Persicaria hydropiperoides and P. punctata (Polygonaceae) on which the immatures induce leaf roll galls. The two new species are morphologically similar to A. persicaria, to which they are probably closely related. A key is provided for the adults and immatures of the Neotropical species of Aphalara. |
Palavras-Chave: |
Leaf roll galls; Psilídeo; Psyllids. |
Thesaurus NAL: |
Persicaria; Polygonaceae; Sternorrhyncha. |
Categoria do assunto: |
O Insetos e Entomologia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/217248/1/Dalva-ZK-article-56807-en-1-1.pdf
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Marc: |
LEADER 01612naa a2200229 a 4500 001 2126070 005 2020-10-29 008 2020 bl uuuu u00u1 u #d 024 7 $a10.3897/zookeys.980.56807$2DOI 100 1 $aBURCKHARDT, D. 245 $aJumping plant lice of the genus Aphalara (Hemiptera, Psylloidea, Aphalaridae) in the Neotropics.$h[electronic resource] 260 $c2020 520 $aThe Neotropical species of the predominantly north temperate genus Aphalara are reviewed. Four species are recorded here from this region, two of which are described as new. Aphalara ritteri sp. nov. occurs in southern Brazil (Paraná, Rio Grande do Sul, Santa Catarina) and represents the first and only species reported from South America. A second new species, Aphalara ortegae sp. nov., is described from Mexico and Puerto Rico. Another two species, Aphalara persicaria Caldwell, 1937 and A. simila Caldwell, 1937, have been previously reported from Mexico and the USA, and one of them also from Cuba. The two new species are both associated with Persicaria hydropiperoides and P. punctata (Polygonaceae) on which the immatures induce leaf roll galls. The two new species are morphologically similar to A. persicaria, to which they are probably closely related. A key is provided for the adults and immatures of the Neotropical species of Aphalara. 650 $aPersicaria 650 $aPolygonaceae 650 $aSternorrhyncha 653 $aLeaf roll galls 653 $aPsilídeo 653 $aPsyllids 700 1 $aDALLE CORT, J. 700 1 $aQUEIROZ, D. L. de 773 $tZooKeys$gv. 980, p. 119-140, 2020.
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