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| Registros recuperados : 10 | |
| 1. |  | BARRIQUELLO, M. F.; PÉREZ, M. G.; NEVES, E. F. A.; MARTIN-NETO, L. Estudo da estrutura de polímeros análogos às substâncias húmicas utilizando RMN de 13C em estado sólido. In: ENCONTRO NACIONAL DE QUÍMICA ANALÍTICA, ENQA, 12. Química Analítica Moderna: uma contribuição para a química limpa., out. 2003., São Luís, MA. Resumos... São Luís, MA. 2003. [CD-ROM]. Ref. OT 017.| Biblioteca(s): Embrapa Instrumentação. |
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| 3. | | SILVA, A. C.; TORRADO, P. V.; MARTIN-NETO, L. VASQUEZ, F. M.; PÉREZ, M. G. Soil organic matter and geomorphic surface stability relationship in an oxisol toposequence (SE BRAZIL). In: INTERNATIONAL MEETING OF INTERNATIONAL HUMIC SUBSTANCES SOCIETY. -- IHSS, 12, São Pedro, SP, 2004. Humic substances and soil and water environment. Abstracts...[São Carlos], SP: Embrapa Instrumentação Agropecuária, 2004. p. 80.| Biblioteca(s): Embrapa Instrumentação. |
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| 4. | | PÉREZ, M. G.; TORRADO, P. V.; MARTIN-NETO, L.; COLNAGO, L. A.; MILON, D. M. P. B.; GOMES, F. H. Study of humic acids from brazilian spodosol by 13C NMR and FTIR spectroscopy. In: NUCLEAR MAGNETIC RESONANCE USERS MEETING, 10.; PORTUGUESE-BRAZILIAN NMR MEETING, 3.; IBERO AMERICAN NMR MEETING 2005, Angra dos Reis. Abstracts... Angra dos Reis: AUREMN, 2005. p. 107.| Biblioteca(s): Embrapa Instrumentação. |
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| 6. | | ÇIÇEK, S. S.; PÉREZ, M. G; WENZEL-STORJOHANN, A.; BEZERRA, R. M.; SEGOVIA, J. F. O.; GIRRESER, U.; KANZAKI, I.; TASDEMIR, D. Antimicrobial prenylated isoflavones from the leaves of the Amazonian medicinal plant vatairea guianensis Aubl. Journal of Natural Products, v. 85, p. 927-935, 2022.| Biblioteca(s): Embrapa Amapá. |
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| 7. | | PÉREZ, M. G.; MILORI, D. M. B. P.; MARTIN NETO, L.; COLNAGO, L. A.; CAMARGO, O. A. de; BERTON, R.; BETTIOL, W. Laser-induced fluorescence of organic matter from a Brazilian oxisol under sewage sludge applications. Scientia Agricola, Piracicaba, v. 63, n. 3, p. 269-275, maio/jun. 2006.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 8. | | PÉREZ, M. G.; MARTIN-NETO, L.; SAAB, S. C.; NOVOTNY, E. H.; MILORI, D. M. B. P.; BAGNATO, V. S.; COLNAGO, L. A.; MELO, W. J.; KNICKER, H. Characterization of humic acids from a brazilian oxisol under different tillage systems by EPR, 13C NMR, FTIR and fluorescence spectroscopy. Geoderma, Amsterdam, v. 118, p. 181-190, 2004.| Biblioteca(s): Embrapa Instrumentação. |
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| 9. | | PÉREZ, M. G.; MARTIN NETO, L.; COLNAGO, L. A.; MILORI, D. M. B. P.; CAMARGO, O. A. de; BERTON, R.; BETTIOL, W. Characterization of humic acids extracted from sewage sludge-amended oxisols by electron paramagnetic resonance. Soil & Tillage Research, Amsterdam, v. 91, p. 95-100, 2006.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 10. | | MARTIN NETO, L.; SIMÕES, M. L.; FERREIRA, J. A.; MILORI, D. M. B. P.; SILVA, W. T. L. da; PEREZ, M. G.; NASCIMENTO, O. R.; BAYER, C.; MIELNICZUK, J. Applications of spectroscopies in humic substances research. In: HUMIC SCIENCE AND TECHNOLOGY, 8., 2005, Boston. Aggregation and physiological effects: [abstracts]. Boston: Northeastern University, 2005.| Biblioteca(s): Embrapa Instrumentação. |
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| Registros recuperados : 10 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Amapá. |
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Data corrente: |
29/07/2022 |
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Data da última atualização: |
08/08/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
ÇIÇEK, S. S.; PÉREZ, M. G; WENZEL-STORJOHANN, A.; BEZERRA, R. M.; SEGOVIA, J. F. O.; GIRRESER, U.; KANZAKI, I.; TASDEMIR, D. |
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Afiliação: |
SERHAT S. ÇIÇEK, KIEL UNIVERSITY; MAYRA GALARZA PÉREZ, KIEL UNIVERSITY; ARLETTE WENZEL-STORJOHANN, GEOMAR; ROBERTO M. BEZERRA, UNIFAP; JORGE FEDERICO ORELLANA SEGOVIA, CPAF-AP; ULRICH GIRRESER, KIEL UNIVERSITY; ISAMU KANZAKI, UNB; DENIZ TASDEMIR, GEOMAR. |
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Título: |
Antimicrobial prenylated isoflavones from the leaves of the Amazonian medicinal plant vatairea guianensis Aubl. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Journal of Natural Products, v. 85, p. 927-935, 2022. |
|
DOI: |
https://doi.org/10.1021/acs.jnatprod.1c01035 |
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Idioma: |
Inglês |
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Conteúdo: |
Vatairea guianenis Aubl. (Fabaceae) is an Amazonian medicinal plant species traditionally used for treating skin diseases. In an initial screening, a V. guianensis leaf extract and its subextracts showed antibacterial and antifungal activities. The EtOAc subextract was selected for chemical workup and afforded five known (1-4 and 8) and six undescribed isoflavones, vatairenones C-H( 5-7 and 9-11). All isoflavones are prenylated in position C-8, displaying either chain-prenylated (1-7) or ring-closed forms (8-11). The most bioactive compound (3) exhibited in vitro activity against clinically relevant bacteria and fungi with IC50 values ranging from 6.8 to 26.9 μM. Due to its broad antimicrobial activity and low general toxicity, compound 3 is a potential lead compound for structural modifications. The results of the present study support the ethnomedicinal use of V. guianensis in the treatment of dermatological disorders. 1H NMR spectra of some of the isolated compounds showed intricate signal patterns, which might explain repeated errors in assigning the correct structure of the isoflavonoid B-ring in the literature and which we resolved by higher order spectra simulations. |
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Thesagro: |
Planta Medicinal. |
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Thesaurus NAL: |
Fabaceae; Medicinal plants. |
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Categoria do assunto: |
F Plantas e Produtos de Origem Vegetal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1145058/1/CPAF-AP-2022-Antimicrobial-Prenylated-Isoflavones.pdf
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|
Marc: |
LEADER 01980naa a2200253 a 4500
001 2145058
005 2022-08-08
008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1021/acs.jnatprod.1c01035$2DOI
100 1 $aÇIÇEK, S. S.
245 $aAntimicrobial prenylated isoflavones from the leaves of the Amazonian medicinal plant vatairea guianensis Aubl.$h[electronic resource]
260 $c2022
520 $aVatairea guianenis Aubl. (Fabaceae) is an Amazonian medicinal plant species traditionally used for treating skin diseases. In an initial screening, a V. guianensis leaf extract and its subextracts showed antibacterial and antifungal activities. The EtOAc subextract was selected for chemical workup and afforded five known (1-4 and 8) and six undescribed isoflavones, vatairenones C-H( 5-7 and 9-11). All isoflavones are prenylated in position C-8, displaying either chain-prenylated (1-7) or ring-closed forms (8-11). The most bioactive compound (3) exhibited in vitro activity against clinically relevant bacteria and fungi with IC50 values ranging from 6.8 to 26.9 μM. Due to its broad antimicrobial activity and low general toxicity, compound 3 is a potential lead compound for structural modifications. The results of the present study support the ethnomedicinal use of V. guianensis in the treatment of dermatological disorders. 1H NMR spectra of some of the isolated compounds showed intricate signal patterns, which might explain repeated errors in assigning the correct structure of the isoflavonoid B-ring in the literature and which we resolved by higher order spectra simulations.
650 $aFabaceae
650 $aMedicinal plants
650 $aPlanta Medicinal
700 1 $aPÉREZ, M. G
700 1 $aWENZEL-STORJOHANN, A.
700 1 $aBEZERRA, R. M.
700 1 $aSEGOVIA, J. F. O.
700 1 $aGIRRESER, U.
700 1 $aKANZAKI, I.
700 1 $aTASDEMIR, D.
773 $tJournal of Natural Products$gv. 85, p. 927-935, 2022.
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