Data/hora: 07/06/2024 08:33:44

Biblioteca(s): 	Embrapa Caprinos e Ovinos; Embrapa Gado de Leite.	
Tipo da produção científica: 	Artigo em Periódico Indexado	
Circulação/Nível: 	A - 2	
Data corrente: 	16/08/2021	
Data da última atualização: 	25/08/2021	
Autoria: 	DIAMANTINO, G. M. L.; PIEREZAN, F.; FERREIRA, M. I. C.; ROCHA, W. S. D. da; OLIVEIRA, V. M. de; MARTINS, C. E.; VEIGA, M. O.; SOTO-BLANCO, B.	
Afiliação: 	GABRIELLA M. L. DIAMANTINO, Universidade Federal de Minas Gerais; FELIPE PIEREZAN, Universidade Federal de Minas Gerais; MARIA IZABEL CARNEIRO FERREIRA, CNPC; WADSON SEBASTIAO DUARTE DA ROCHA, CNPGL; VANIA MARIA DE OLIVEIRA, CNPGL; CARLOS EUGENIO MARTINS, CNPGL; MAÍRA O. VEIGA, Universidade Federal de Lavras; BENITO SOTO-BLANCO, Universidade Federal de Minas Gerais.	
Título: 	Photosensitization by Brachiaria ruziziensis in a sheep herd.	
Ano de publicação: 	2020	
Fonte/Imprenta: 	Toxicon, v. 185, p. 1-4, 2020.	
DOI: 	https://doi.org/10.1016/j.toxicon.2020.06.022	
Idioma: 	Inglês	
Conteúdo: 	Some species of the genus Brachiaria are cultivated worldwide in tropical and subtropical climate regions as the main feed for ruminants. Several studies report photosensitization by Brachiaria decumbens, Brachiaria brizantha, and Brachiaria humidicola, but the poisoning by Brachiaria ruziziensis have been reported only twice. Cutaneous and hepatic lesions may be caused by the steroidal saponins present in the leaves or by the mycotoxin sporidesmin produced by the saprophyte fungus Pithomyces chartarum. The present report describes the clinical and pathological changes observed in an outbreak of hepatogenic photosensitization in sheep kept in B. ruziziensis pastures. In addition, the present study will provide a better understanding of the etiology of this photosensitization through the evaluation of the saponin protodioscin and the spore count of P. chartarum. Santa In^es and Lacaune mixed-breed sheep showed signs of photosensitization after feeding B. ruziziensis. Clinical signs included jaundice, apathy, dehydration, and photosensitization characterized by facial edema and cutaneous scars, especially in the ears. Pathological examination of the liver revealed diffuse infiltrates of foamy cells, rare
multinucleated cells, and mild enlargement of hepatocytes (megalocytosis). The skin showed acute epidermal and dermal necrosis with occlusive thrombi. B. ruziziensis showed low levels of protodioscin (0.020 +- 0.024% in mature leaves and 0.065 +- 0.084% in sprouts) but high P. chartarum spore counts (mean of 479,844 +- 443,951 spores/g plant). Thus, sheep grazing B. ruziziensis pastures must be closely monitored because of the risk of photosensitization.	
Thesagro: 	Fotossensibilização; Ovelha; Ovino; Pastagem; Saponina.	
Thesaurus Nal: 	Pithomyces; Plant poisoning.	
Categoria do assunto: 	L Ciência Animal e Produtos de Origem Animal	
Registro original: 	Embrapa Caprinos e Ovinos (CNPC)	
Exemplares: 	CNPGL - (25224-1) - UPC - AP - DD -  -  -  - DIS
CNPC - (39865-1) - UPC - AP - DD -  -  -  - DIS