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Registros recuperados : 9 | |
1. | | EL HALAL, S. L. M.; KRINGEL, D.; MIRANDA, M. Z. de; DIAS, A. R. G.; ZAVAREZE, E. da R. Soy lecithin as an improver during freeze bread storage. In: INTERNATIONAL GLUTEN WORKSHOP, 13., 2018, Mexico. Book of abstracts... Mexico, DC: CIMMYT, 2018. p. 65. Biblioteca(s): Embrapa Trigo. |
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2. | | EL HALAL, S. L. M.; KRINGEL, D.; MIRANDA, M. Z. de; DIAS, A. R. G.; ZAVAREZE, E. da R. Soy lecithin as an improver during freeze bread storage. In: INTERNATIONAL GLUTEN WORKSHOP, 13., 2018, Mexico City, Mexico. Proceedings... Córdoba: UCO Press Editorial Universidad de Córdoba, 2019. p. 94-96. LACC/IGW. Biblioteca(s): Embrapa Trigo. |
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4. | | BARANZELLI, J.; HALAL, S. L. M.; KRINGEL, D. H.; PINTO, V. Z.; PAIVA, F. F.; ZAVAREZE, E.; MIRANDA, M. Z. de; DIAS, A. R. G. Atividade enzimática de trigo germinado em diferentes tempos e umidades. In: SIMPOSIO DE ALIMENTOS, 9., 2015, Passo Fundo. A indústria de alimentos e a saúde do consumidor: [anais]. Passo Fundo: UPF, 2015. Ciência de alimentos, trabalho C41. 6 p. Biblioteca(s): Embrapa Trigo. |
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5. | | VANIER, N. L.; OLIVEIRA, J. P. de; BRUNI, G. P.; EL HALAL, S. L. M.; VILLANOVA, F. A.; ZAVAREZE, E. da R.; DIAS, A. R. G.; BASSINELLO, P. Z. Characteristics of starch from different bean genotypes and its effect on biodegradable films. Journal of the Science of Food and Agriculture, v. 99, n. 3, p. 1207-1214, Feb. 2019. Biblioteca(s): Embrapa Arroz e Feijão. |
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6. | | BARANZELLI, J.; KRINGEL, D. H.; MALLMANN, J. F.; BOCK, E.; EL HALAL, S. L. M.; PRIETTO, L.; ZAVAREZE, E. da R.; MIRANDA, M. Z. de; DIAS, A. R. G. Impact of wheat (Triticum aestivum L.) germination process on starch properties for application in films. Starch, v. 71, n. 7, 1800262, 2019. 8 p. Biblioteca(s): Embrapa Trigo. |
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7. | | SILVA, W. P. da; GOLDBECK, J. C.; MAIA, D. S. V.; EL HALAL, S. L. M.; COLUSSI, R.; ZAVAREZE, E. da R.; DIAS, R. G.; JACOB, R. G.; LENARDÃO, E. J. Antimicrobial activity of 3-(p-chlorophenyl)thio citronellal against planktonic and biofilm Staphylococcus aureus cells and its application in biodegradable films. Food Packaging and Shelf Life, v. 22 (2019) 100375 Biblioteca(s): Embrapa Clima Temperado. |
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8. | | BRUNI, G. P.; OLIVEIRA, J. P. de; EL HALAL, S. L. M.; FLORES, W. H.; GUNDEL, A.; MIRANDA, M. Z. de; ZAVAREZE, E. da R.; DIAS, A. R. G. Phosphorylated and cross-linked wheat starches in the presence of polyethylene oxide and their application in biocomposite films. Starch, 1700192, mar. 2018. 9 p. Biblioteca(s): Embrapa Trigo. |
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9. | | ZAVAREZE, E. da R.; TELLES, A. C.; EL HALAL, S. L. M.; ROCHA, M. da; COLUSSI, R.; ASSIS, L. M. de; CASTRO, L. A. S. de; DIAS, A. R. G.; PRENTICE-HERNÁNDEZ, C. Production and characterization of encapsulated antioxidative protein hydrolysates from Whitemouth croaker (Micropogonias furnieri) muscle and byproduct. Food Science and Technology, v. 59, p. 841-848, 2014. Biblioteca(s): Embrapa Clima Temperado. |
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Registros recuperados : 9 | |
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Registro Completo
Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
Data corrente: |
30/04/2021 |
Data da última atualização: |
05/05/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 2 |
Autoria: |
CARDOSO, T. F.; COUTINHO, L. L.; BRUSCADIN, J. J.; DINIZ, W. J. da S.; PETRINI, J.; ANDRADE, B. G. N.; OLIVEIRA, P. S. N. de; POLETI, M. D.; CESAR, A. S. M.; SILVEIRA, J. C. DA; CHIARATTI, M. R.; ZERLOTINI NETO, A.; MOURÃO, G. B.; REGITANO, L. C. de A. |
Afiliação: |
TAINÃ FIGUEIREDO CARDOSO; LUIZ LEHMANN COUTINHO, ESALQ/USP; JENNIFER JESSICA BRUSCADIN, UFSCAR; WELLISON JARLES DA SILVA DINIZ, North Dakota State University; JULIANA PETRINI, ESALQ/USP; BRUNO GABRIEL NASCIMENTO ANDRADE; PRISCILA SILVA NEUBERN DE OLIVEIRA, UFSCAR; MIRELE DAIANA POLETI, USP; ALINE SILVA MELLO CESAR, ESALQ/USP; JULIANO COELHO DA SILVEIRA, USP; MARCOS ROBERTO CHIARATTI, UFSCAR; ADHEMAR ZERLOTINI NETO, CNPTIA; GERSON BARRETO MOURÃO, ESALQ/USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
Título: |
Multi-omics approach reveals miR-SNPs affecting muscle fatty acids profile in Nelore cattle. |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Genes, v. 12, n. 1, p. 1-18, Jan. 2021. |
DOI: |
https://doi.org/10.3390/genes12010067 |
Idioma: |
Inglês |
Notas: |
Article 67. Na publicação: Adhemar Zerlotini. |
Conteúdo: |
MicroRNAs (miRNAs) are key regulators of gene expression, potentially affecting several biological processes, whose function can be altered by sequence variation. Hence, the integration of single nucleotide polymorphisms (SNP) and miRNAs can explain individual differences in economic traits. To provide new insights into the effects of SNPs on miRNAs and their related target genes, we carried out a multi-omic analysis to identify SNPs in miRNA mature sequences (miR-SNPs) associated with fatty acid (FA) composition in the Nelore cattle. As a result, we identified 3 miR-SNPs in different miRNAs (bta-miR-2419-3p, bta-miR-193a-2, and bta-miR-1291) significantly associated with FA traits (p-value < 0.02, Bonferroni corrected). Among these, the rs110817643C>T, located in the seed sequence of the bta-miR-1291, was associated with different ?6 FAs, polyunsaturated FA, and polyunsaturated:saturated FA ratios. Concerning the other two miR-SNPs, the rs43400521T>C (located in the bta-miR-2419-3p) was associated with C12:0 and C18:1 cis-11 FA, whereas the rs516857374A>G (located in the bta-miR-193a-2) was associated with C18:3 ?6 and ratio of ?6/?3 traits. Additionally, to identify potential biomarkers for FA composition, we described target genes affected by these miR-SNPs at the mRNA or protein level. Our multi-omics analysis outlines the effects of genetic polymorphism on miRNA, and it highlights miR-SNPs and target candidate genes that control beef fatty acid composition. |
Palavras-Chave: |
Análise multiômica; Association analysis; Expressão gênica; MiRNAs; Polimorfismo de nucleotídeo único. |
Thesagro: |
Bos Indicus. |
Thesaurus NAL: |
Beef quality; Gene expression; Polymorphism; Single nucleotide polymorphism. |
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/223016/1/AP-Multi-omics-approach-2021.pdf
|
Marc: |
LEADER 02779naa a2200421 a 4500 001 2131655 005 2021-05-05 008 2021 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.3390/genes12010067$2DOI 100 1 $aCARDOSO, T. F. 245 $aMulti-omics approach reveals miR-SNPs affecting muscle fatty acids profile in Nelore cattle.$h[electronic resource] 260 $c2021 500 $aArticle 67. Na publicação: Adhemar Zerlotini. 520 $aMicroRNAs (miRNAs) are key regulators of gene expression, potentially affecting several biological processes, whose function can be altered by sequence variation. Hence, the integration of single nucleotide polymorphisms (SNP) and miRNAs can explain individual differences in economic traits. To provide new insights into the effects of SNPs on miRNAs and their related target genes, we carried out a multi-omic analysis to identify SNPs in miRNA mature sequences (miR-SNPs) associated with fatty acid (FA) composition in the Nelore cattle. As a result, we identified 3 miR-SNPs in different miRNAs (bta-miR-2419-3p, bta-miR-193a-2, and bta-miR-1291) significantly associated with FA traits (p-value < 0.02, Bonferroni corrected). Among these, the rs110817643C>T, located in the seed sequence of the bta-miR-1291, was associated with different ?6 FAs, polyunsaturated FA, and polyunsaturated:saturated FA ratios. Concerning the other two miR-SNPs, the rs43400521T>C (located in the bta-miR-2419-3p) was associated with C12:0 and C18:1 cis-11 FA, whereas the rs516857374A>G (located in the bta-miR-193a-2) was associated with C18:3 ?6 and ratio of ?6/?3 traits. Additionally, to identify potential biomarkers for FA composition, we described target genes affected by these miR-SNPs at the mRNA or protein level. Our multi-omics analysis outlines the effects of genetic polymorphism on miRNA, and it highlights miR-SNPs and target candidate genes that control beef fatty acid composition. 650 $aBeef quality 650 $aGene expression 650 $aPolymorphism 650 $aSingle nucleotide polymorphism 650 $aBos Indicus 653 $aAnálise multiômica 653 $aAssociation analysis 653 $aExpressão gênica 653 $aMiRNAs 653 $aPolimorfismo de nucleotídeo único 700 1 $aCOUTINHO, L. L. 700 1 $aBRUSCADIN, J. J. 700 1 $aDINIZ, W. J. da S. 700 1 $aPETRINI, J. 700 1 $aANDRADE, B. G. N. 700 1 $aOLIVEIRA, P. S. N. de 700 1 $aPOLETI, M. D. 700 1 $aCESAR, A. S. M. 700 1 $aSILVEIRA, J. C. DA 700 1 $aCHIARATTI, M. R. 700 1 $aZERLOTINI NETO, A. 700 1 $aMOURÃO, G. B. 700 1 $aREGITANO, L. C. de A. 773 $tGenes$gv. 12, n. 1, p. 1-18, Jan. 2021.
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Embrapa Agricultura Digital (CNPTIA) |
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