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Registro Completo |
Biblioteca(s): |
Embrapa Agroenergia. |
Data corrente: |
23/11/2022 |
Data da última atualização: |
23/11/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
CARNEIRO, C. V. G. C.; SERRA, L. A.; PACHECO, T. F.; FERREIRA, L. M. M.; DUARTE, L. T.; FREITAS, M. N. de M.; TRICHEZ, D.; ALMEIDA, J. R. M. de. |
Afiliação: |
CLARA VIDA GALRÃO CORRÊA CARNEIRO, UNB/CNPAE; LUANA ASSIS SERRA, UNB/CNPAE; THALYTA FRAGA PACHECO, CNPAE; LETÍCIA MARIA MALLMANN FERREIRA, UNB/CNPAE; LIVIA TEIXEIRA DUARTE BRANDAO, CNPAE; MARIANA NOGUEIRA DE MOURA FREITAS, UNB/CNPAE; DÉBORA TRICHEZ, UNB/CNPAE; JOAO RICARDO MOREIRA DE ALMEIDA, CNPAE. |
Título: |
Advances in Komagataella phaffii Engineering for the Production of Renewable Chemicals and Proteins |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Fermentation, v. 8, n. 575, p. 2-37, 2022. |
DOI: |
https://doi.org/10.3390/fermentation8110575 |
Idioma: |
Inglês |
Conteúdo: |
The need for a more sustainable society has prompted the development of bio-based processes to produce fuels, chemicals, and materials in substitution for fossil-based ones. In this context, microorganisms have been employed to convert renewable carbon sources into various products. The methylotrophic yeast Komagataella phaffii has been extensively used in the production of heterologous proteins. More recently, it has been explored as a host organism to produce various chemicals through new metabolic engineering and synthetic biology tools. This review first summarizes Komagataella taxonomy and diversity and then highlights the recent approaches in cell engineering to produce renewable chemicals and proteins. Finally, strategies to optimize and develop new fermentative processes using K. phaffii as a cell factory are presented and discussed. The yeast K. phaffii shows an outstanding performance for renewable chemicals and protein production due to its ability to metabolize different carbon sources and the availability of engineering tools. Indeed, it has been employed in producing alcohols, carboxylic acids, proteins, and other compounds using different carbon sources, including glycerol, glucose, xylose, methanol, and even CO2. |
Palavras-Chave: |
Komagataella phaffii. |
Thesagro: |
Biologia Vegetal. |
Thesaurus Nal: |
Bioengineering; Pichia pastoris. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1148607/1/Advances-in-komagataella-phaffii.pdf
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Marc: |
LEADER 02069naa a2200265 a 4500 001 2148607 005 2022-11-23 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.3390/fermentation8110575$2DOI 100 1 $aCARNEIRO, C. V. G. C. 245 $aAdvances in Komagataella phaffii Engineering for the Production of Renewable Chemicals and Proteins$h[electronic resource] 260 $c2022 520 $aThe need for a more sustainable society has prompted the development of bio-based processes to produce fuels, chemicals, and materials in substitution for fossil-based ones. In this context, microorganisms have been employed to convert renewable carbon sources into various products. The methylotrophic yeast Komagataella phaffii has been extensively used in the production of heterologous proteins. More recently, it has been explored as a host organism to produce various chemicals through new metabolic engineering and synthetic biology tools. This review first summarizes Komagataella taxonomy and diversity and then highlights the recent approaches in cell engineering to produce renewable chemicals and proteins. Finally, strategies to optimize and develop new fermentative processes using K. phaffii as a cell factory are presented and discussed. The yeast K. phaffii shows an outstanding performance for renewable chemicals and protein production due to its ability to metabolize different carbon sources and the availability of engineering tools. Indeed, it has been employed in producing alcohols, carboxylic acids, proteins, and other compounds using different carbon sources, including glycerol, glucose, xylose, methanol, and even CO2. 650 $aBioengineering 650 $aPichia pastoris 650 $aBiologia Vegetal 653 $aKomagataella phaffii 700 1 $aSERRA, L. A. 700 1 $aPACHECO, T. F. 700 1 $aFERREIRA, L. M. M. 700 1 $aDUARTE, L. T. 700 1 $aFREITAS, M. N. de M. 700 1 $aTRICHEZ, D. 700 1 $aALMEIDA, J. R. M. de 773 $tFermentation$gv. 8, n. 575, p. 2-37, 2022.
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Registro original: |
Embrapa Agroenergia (CNPAE) |
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Registro Completo
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
Data corrente: |
05/03/2008 |
Data da última atualização: |
22/06/2023 |
Tipo da produção científica: |
Boletim de Pesquisa e Desenvolvimento |
Autoria: |
OLIVEIRA, M. C. de S.; OLIVEIRA, H. N. de; REGITANO, L. C. de A.; ALENCAR, M. M. de; NÉO, T. A.; SILVA, A. M. da. |
Afiliação: |
MARCIA CRISTINA DE SENA OLIVEIRA, CPPSE; HENRIQUE NUNES DE OLIVEIRA, UNESP/Botucatu SP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; MAURICIO MELLO DE ALENCAR, CPPSE; THALITA ATHIÊ NÉO, Bolsista do PIBIC; ANA MARY DA SILVA, Bolsista do CNPq. |
Título: |
Estudo da infecção por Babesia bigemina em bovinos de corte e em carrapatos. |
Ano de publicação: |
2007 |
Fonte/Imprenta: |
São Carlos, SP: Embrapa Pecuária Sudeste, 2007. |
Páginas: |
26 p. |
Série: |
(Boletim de pesquisa e desenvolvimento / Embrapa Pecuária Sudeste; 12). |
Idioma: |
Português |
Palavras-Chave: |
Carrapatos. |
Thesagro: |
Babesia Bigemina; Gado de Corte; Infecção. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/CPPSE/17523/1/Boletim12.pdf
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Marc: |
LEADER 00738nam a2200229 a 4500 001 1044885 005 2023-06-22 008 2007 bl uuuu u0uu1 u #d 100 1 $aOLIVEIRA, M. C. de S. 245 $aEstudo da infecção por Babesia bigemina em bovinos de corte e em carrapatos.$h[electronic resource] 260 $aSão Carlos, SP: Embrapa Pecuária Sudeste$c2007 300 $a26 p. 490 $a(Boletim de pesquisa e desenvolvimento / Embrapa Pecuária Sudeste; 12). 650 $aBabesia Bigemina 650 $aGado de Corte 650 $aInfecção 653 $aCarrapatos 700 1 $aOLIVEIRA, H. N. de 700 1 $aREGITANO, L. C. de A. 700 1 $aALENCAR, M. M. de 700 1 $aNÉO, T. A. 700 1 $aSILVA, A. M. da
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