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Registro Completo |
Biblioteca(s): |
Embrapa Pecuária Sul. |
Data corrente: |
10/05/2011 |
Data da última atualização: |
04/08/2011 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
STEIBEL, J. P.; BATES, R. O.; ROSA, G. J. M.; TEMPELMAN, R. J.; RILINGTON, V. D.; RAGAVENDRAN, A.; RANEY, NANCY E.; RAMOS, A. M.; CARDOSO, F. F.; EDWARDS, D. B.; ERNST, C. W. |
Afiliação: |
JUAN PEDRO STEIBEL, Department of Animal Science, Michigan State University; RONALD O. BATES, Department of Animal Science, Michigan State University; GUILHERME J. M. ROSA, Department of Animal Sciences, University of Wisconsin; ROBERT J. TEMPELMAN, Department of Animal Science, Michigan State University; VALENCIA D. RILINGTON, Department of Animal Science, Michigan State University; ASHOK RAGAVENDRAN, Department of Animal Science, Michigan State University; NANCY E. RANEY, Department of Animal Science, Michigan State University; ANTONIO MARCOS RAMOS, Department of Animal Science, Michigan State University; FERNANDO FLORES CARDOSO, CPPSUL; DAVID B. EDWARDS, Department of Animal Science, Michigan State University; ERNST, C. W., Department of Animal Science, Michigan State University. |
Título: |
Genome-wide linkage analysis of global gene expression in loin muscle tissue identifies candidate genes in pigs. |
Ano de publicação: |
2011 |
Fonte/Imprenta: |
PLoS ONE, San Francisco, v. 6, n. 2, e16766, Feb. 2011. |
Idioma: |
Inglês |
Conteúdo: |
Background: Nearly 6,000 QTL have been reported for 588 different traits in pigs, more than in any other livestock species. However, this effort has translated into only a few confirmed causative variants. A powerful strategy for revealing candidate genes involves expression QTL (eQTL) mapping, where the mRNA abundance of a set of transcripts is used as the response variable for a QTL scan. Methodology/Principal Findings: We utilized a whole genome expression microarray and an F2 pig resource population to conduct a global eQTL analysis in loin muscle tissue, and compared results to previously inferred phenotypic QTL (pQTL) from the same experimental cross. We found 62 unique eQTL (FDR ,10%) and identified 3 gene networks enriched with genes subject to genetic control involved in lipid metabolism, DNA replication, and cell cycle regulation. We observed strong evidence of local regulation (40 out of 59 eQTL with known genomic position) and compared these eQTL to pQTL to help identify potential candidate genes. Among the interesting associations, we found aldo-keto reductase 7A2 (AKR7A2) and thioredoxin domain containing 12 (TXNDC12) eQTL that are part of a network associated with lipid metabolism and in turn overlap with pQTL regions for marbling, % intramuscular fat (% fat) and loin muscle area on Sus scrofa (SSC) chromosome 6. Additionally, we report 13 genomic regions with overlapping eQTL and pQTL involving 14 local eQTL. Conclusions/Significance: Results of this analysis provide novel candidate genes for important complex pig phenotypes. MenosBackground: Nearly 6,000 QTL have been reported for 588 different traits in pigs, more than in any other livestock species. However, this effort has translated into only a few confirmed causative variants. A powerful strategy for revealing candidate genes involves expression QTL (eQTL) mapping, where the mRNA abundance of a set of transcripts is used as the response variable for a QTL scan. Methodology/Principal Findings: We utilized a whole genome expression microarray and an F2 pig resource population to conduct a global eQTL analysis in loin muscle tissue, and compared results to previously inferred phenotypic QTL (pQTL) from the same experimental cross. We found 62 unique eQTL (FDR ,10%) and identified 3 gene networks enriched with genes subject to genetic control involved in lipid metabolism, DNA replication, and cell cycle regulation. We observed strong evidence of local regulation (40 out of 59 eQTL with known genomic position) and compared these eQTL to pQTL to help identify potential candidate genes. Among the interesting associations, we found aldo-keto reductase 7A2 (AKR7A2) and thioredoxin domain containing 12 (TXNDC12) eQTL that are part of a network associated with lipid metabolism and in turn overlap with pQTL regions for marbling, % intramuscular fat (% fat) and loin muscle area on Sus scrofa (SSC) chromosome 6. Additionally, we report 13 genomic regions with overlapping eQTL and pQTL involving 14 local eQTL. Conclusions/Significance: Results of this analysis... Mostrar Tudo |
Thesagro: |
Genética; Suíno. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/33973/1/METAS-2011-FFC-Steibel-et-al-2011-PLoS-ONE-62-e16766.pdf
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Marc: |
LEADER 02341naa a2200265 a 4500 001 1888216 005 2011-08-04 008 2011 bl uuuu u00u1 u #d 100 1 $aSTEIBEL, J. P. 245 $aGenome-wide linkage analysis of global gene expression in loin muscle tissue identifies candidate genes in pigs.$h[electronic resource] 260 $c2011 520 $aBackground: Nearly 6,000 QTL have been reported for 588 different traits in pigs, more than in any other livestock species. However, this effort has translated into only a few confirmed causative variants. A powerful strategy for revealing candidate genes involves expression QTL (eQTL) mapping, where the mRNA abundance of a set of transcripts is used as the response variable for a QTL scan. Methodology/Principal Findings: We utilized a whole genome expression microarray and an F2 pig resource population to conduct a global eQTL analysis in loin muscle tissue, and compared results to previously inferred phenotypic QTL (pQTL) from the same experimental cross. We found 62 unique eQTL (FDR ,10%) and identified 3 gene networks enriched with genes subject to genetic control involved in lipid metabolism, DNA replication, and cell cycle regulation. We observed strong evidence of local regulation (40 out of 59 eQTL with known genomic position) and compared these eQTL to pQTL to help identify potential candidate genes. Among the interesting associations, we found aldo-keto reductase 7A2 (AKR7A2) and thioredoxin domain containing 12 (TXNDC12) eQTL that are part of a network associated with lipid metabolism and in turn overlap with pQTL regions for marbling, % intramuscular fat (% fat) and loin muscle area on Sus scrofa (SSC) chromosome 6. Additionally, we report 13 genomic regions with overlapping eQTL and pQTL involving 14 local eQTL. Conclusions/Significance: Results of this analysis provide novel candidate genes for important complex pig phenotypes. 650 $aGenética 650 $aSuíno 700 1 $aBATES, R. O. 700 1 $aROSA, G. J. M. 700 1 $aTEMPELMAN, R. J. 700 1 $aRILINGTON, V. D. 700 1 $aRAGAVENDRAN, A. 700 1 $aRANEY, NANCY E. 700 1 $aRAMOS, A. M. 700 1 $aCARDOSO, F. F. 700 1 $aEDWARDS, D. B. 700 1 $aERNST, C. W. 773 $tPLoS ONE, San Francisco$gv. 6, n. 2, e16766, Feb. 2011.
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Registro original: |
Embrapa Pecuária Sul (CPPSUL) |
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Registro Completo
Biblioteca(s): |
Embrapa Semiárido. |
Data corrente: |
18/07/1996 |
Data da última atualização: |
03/12/2014 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
Nacional - B |
Autoria: |
NASCIMENTO, C. E. de S. |
Afiliação: |
CLOVIS EDUARDO DE SOUZA NASCIMENTO, CPATSA. |
Título: |
Efeito do acido indolbutirico sobre o enraizamento de estacas semi-lenhosas de acerola. |
Ano de publicação: |
1991 |
Fonte/Imprenta: |
Revista Brasileira de Fruticultura, Cruz das Almas, v. 13, n. 3, p. 255-257, out. 1991. |
Idioma: |
Português |
Conteúdo: |
O presente estudo foi desenvolvido com o objetivo de avaliar o efeito do acido indolbutirico (AIB) nas concentracoes de 0, 2000, 4000, 6000 e 8000 ppm, misturado em talco e captan sobre o enraizamento de estacas semi-lenhosas de plantas de acerola, em casa de vegetacao, a uma temperatura de 25-30oC e umidade de 70-80%, com nebulizacao controlada atraves de umidostato. O delineamento estatistico utilizado foi o de blocos ao acaso, com cinco tratamentos, tres blocos e quatro estacas por parcela, plantadas em sacos de polietileno contendo areia lavada mais vermiculita (4:1) como substrato. Os resultados obtidos permitiram concluir que diferentes dosagens de acido indolbutirico nao mostraram significancia no favorecimento do enraizamento e brotacao das estacas. |
Palavras-Chave: |
Barbados cherry; Estaquia; Pulverization; West indian cherry. |
Thesagro: |
Acerola; Malpighia Glabra; Propagação Vegetativa; Pulverização. |
Thesaurus NAL: |
cutting; vegetative propagation. |
Categoria do assunto: |
A Sistemas de Cultivo |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/112962/1/ID-7664.pdf
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Marc: |
LEADER 01488naa a2200241 a 4500 001 1132675 005 2014-12-03 008 1991 bl uuuu u00u1 u #d 100 1 $aNASCIMENTO, C. E. de S. 245 $aEfeito do acido indolbutirico sobre o enraizamento de estacas semi-lenhosas de acerola. 260 $c1991 520 $aO presente estudo foi desenvolvido com o objetivo de avaliar o efeito do acido indolbutirico (AIB) nas concentracoes de 0, 2000, 4000, 6000 e 8000 ppm, misturado em talco e captan sobre o enraizamento de estacas semi-lenhosas de plantas de acerola, em casa de vegetacao, a uma temperatura de 25-30oC e umidade de 70-80%, com nebulizacao controlada atraves de umidostato. O delineamento estatistico utilizado foi o de blocos ao acaso, com cinco tratamentos, tres blocos e quatro estacas por parcela, plantadas em sacos de polietileno contendo areia lavada mais vermiculita (4:1) como substrato. Os resultados obtidos permitiram concluir que diferentes dosagens de acido indolbutirico nao mostraram significancia no favorecimento do enraizamento e brotacao das estacas. 650 $acutting 650 $avegetative propagation 650 $aAcerola 650 $aMalpighia Glabra 650 $aPropagação Vegetativa 650 $aPulverização 653 $aBarbados cherry 653 $aEstaquia 653 $aPulverization 653 $aWest indian cherry 773 $tRevista Brasileira de Fruticultura, Cruz das Almas$gv. 13, n. 3, p. 255-257, out. 1991.
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