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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
31/10/2018 |
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Data da última atualização: |
03/01/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
DINIZ, W. J. S.; ROSA, K. O.; COUTINHO, L. L.; TIZIOTO, P. C.; OLIVEIRA, P. S. N. de; SOUZA, M. M. de S.; CHAVES, A. S.; LANNA, D. P. D.; MOURÃO, G. B.; REGITANO, L. C. de A. |
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Afiliação: |
Wellison J. S. Diniz, UFSCAR; Kamila O. Rosa, UNESP; Luiz L. Coutinho, USP/ESALQ; Polyana C. Tizioto, USP/ESALQ; Priscila Silva Neubern de Oliveira; Marcela M. de Souza; Amália S. Chaves, UFMG; Dante P. D. Lanna, USP/ESALQ; Gerson B. Mourão, ESALQ/USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
KCNJ11 gene expression is associated to feed consumption and growth traits in Nelore beef cattle. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
Agri Gene, v. 9, p. 1-4, 2018. |
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DOI: |
10.1016/j.aggene.2018.05.004 |
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Idioma: |
Inglês |
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Conteúdo: |
Feed efficiency is a complex trait influenced by several genes and biological processes. However, there is limited knowledge about the genes and pathways involved in this trait. KCNJ11, related to the insulin secretion pathway, was shown to be a functional candidate gene for beef quality traits in Nelore. Given its role in energy metabolism, we evaluated the effects of KCNJ11 gene expression level on feed efficiency-related, carcass and growth traits in Nelore steers. Skeletal muscle KCNJ11 mRNA levels were positively and significantly associated with dry matter intake (DMI), total digestible nutrients consumption (TDN), average daily gain (ADG), and relative growth rate (RGR) from a general linear mixed model approach. Co-expression analysis, using RNA sequencing data obtained from Longissimus dorsi (LD) muscle of 30 Nelore steers, identified key signalling pathways related to the regulation of energy metabolisms, such as mitogen-activated protein kinases and insulin pathways. Our findings indicate a linear relationship between KCNJ11 gene expression and the phenotypic measures for feed intake, weight gain, and relative growth rate in Nelore steers, but not for residual feed intake or fat deposition traits. |
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Palavras-Chave: |
KCNJ11. |
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Thesagro: |
Gado de Corte; Gado Nelore; Novilho de Corte. |
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Thesaurus Nal: |
Beef cattle; Dry matter intake. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 02124naa a2200313 a 4500
001 2098540
005 2019-01-03
008 2018 bl uuuu u00u1 u #d
024 7 $a10.1016/j.aggene.2018.05.004$2DOI
100 1 $aDINIZ, W. J. S.
245 $aKCNJ11 gene expression is associated to feed consumption and growth traits in Nelore beef cattle.$h[electronic resource]
260 $c2018
520 $aFeed efficiency is a complex trait influenced by several genes and biological processes. However, there is limited knowledge about the genes and pathways involved in this trait. KCNJ11, related to the insulin secretion pathway, was shown to be a functional candidate gene for beef quality traits in Nelore. Given its role in energy metabolism, we evaluated the effects of KCNJ11 gene expression level on feed efficiency-related, carcass and growth traits in Nelore steers. Skeletal muscle KCNJ11 mRNA levels were positively and significantly associated with dry matter intake (DMI), total digestible nutrients consumption (TDN), average daily gain (ADG), and relative growth rate (RGR) from a general linear mixed model approach. Co-expression analysis, using RNA sequencing data obtained from Longissimus dorsi (LD) muscle of 30 Nelore steers, identified key signalling pathways related to the regulation of energy metabolisms, such as mitogen-activated protein kinases and insulin pathways. Our findings indicate a linear relationship between KCNJ11 gene expression and the phenotypic measures for feed intake, weight gain, and relative growth rate in Nelore steers, but not for residual feed intake or fat deposition traits.
650 $aBeef cattle
650 $aDry matter intake
650 $aGado de Corte
650 $aGado Nelore
650 $aNovilho de Corte
653 $aKCNJ11
700 1 $aROSA, K. O.
700 1 $aCOUTINHO, L. L.
700 1 $aTIZIOTO, P. C.
700 1 $aOLIVEIRA, P. S. N. de
700 1 $aSOUZA, M. M. de S.
700 1 $aCHAVES, A. S.
700 1 $aLANNA, D. P. D.
700 1 $aMOURÃO, G. B.
700 1 $aREGITANO, L. C. de A.
773 $tAgri Gene$gv. 9, p. 1-4, 2018.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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Registro Completo
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Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
13/03/2009 |
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Data da última atualização: |
08/05/2024 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
PAULA, D.; MAGALHÃES, M.; SUJII, E.; PIRES, C.; FONTES, E.; NAKASU, E. |
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Afiliação: |
DÉBORA PIRES PAULA, EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA; M. MAGALHÃES, UNB; EDISON RYOITI SUJII, EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA; CARMEN SILVA PIRES, EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA; ELIANA MARIA GOUVEIA FONTES, EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA; ERICH YUKIO TEMPEL NAKASU. |
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Título: |
Assessment of the effects of Cry1ac toxin to the butterfly Chlosyne lacinia. |
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Ano de publicação: |
2008 |
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Fonte/Imprenta: |
In: INTERNATIONAL SYMPOSIUM ON THE BIOSAFETY OF GENETICALLY MODIFIED ORGANISMS, 10., 2008, Wellington. Symposium handbook. Wellington: International Society for Biosafety Research, 2008. p.134. |
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Idioma: |
Inglês |
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Palavras-Chave: |
Chlosyne lacinia. |
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Thesagro: |
Borboleta. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/190665/1/1340001.pdf
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Marc: |
LEADER 00676nam a2200181 a 4500
001 1190665
005 2024-05-08
008 2008 bl uuuu u00u1 u #d
100 1 $aPAULA, D.
245 $aAssessment of the effects of Cry1ac toxin to the butterfly Chlosyne lacinia.$h[electronic resource]
260 $aIn: INTERNATIONAL SYMPOSIUM ON THE BIOSAFETY OF GENETICALLY MODIFIED ORGANISMS, 10., 2008, Wellington. Symposium handbook. Wellington: International Society for Biosafety Research, 2008. p.134.$c2008
650 $aBorboleta
653 $aChlosyne lacinia
700 1 $aMAGALHÃES, M.
700 1 $aSUJII, E.
700 1 $aPIRES, C.
700 1 $aFONTES, E.
700 1 $aNAKASU, E.
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Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
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