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| Registros recuperados : 4 | |
| 1. |  | ROMEIRA, K. M.; ABDALLA, G.; GONÇALVES, R. P.; PEGORIN, G. S.; AZEREDO, H. M. C. de; MUSSAGY, C. U.; HERCULANO, R. D. Residual starch packaging derived from potato washing slurries to preserve fruits. Food and Bioprocess Technology, v. 14, p. 2248?2259, 2021.| Biblioteca(s): Embrapa Agroindústria Tropical. |
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| 2. | | MUSSAGY, C. U.; FARIAS, F. O.; SASAKI, J. C.; SCONTRI, M.; PICHELI, F.; SANTOS-EBINUMA, V. C.; AZEREDO, H. M. C. de; PESSOA JR., A. P.; HERCULANO, R. D. Eutectic solvent-based bioactive films functionalized with microbial astaxanthin extends shelf life of fresh strawberries. Materials Today Chemistry, v. 33, 101721, 2023.| Biblioteca(s): Embrapa Instrumentação. |
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| 3. | | BORGES, F. A.; DRAGO, B. C.; BAGGIO, L. O.; BARROS, N. R. de; BRASIL, G. S. P.; SCONTRI, M.; MUSSAGY, C. U.; RIBEIRO, M. C. S.; MILORI, D. M. B. P.; MORAIS, C. P. de; MARANGONI, B. S.; NICOLODELLI, G.; MECWAN, M.; MANDAL, K.; GUERRA, N. B.; MENEGATTI, C. R.; HERCULANO, R. D. Metronidazole-loaded gold nanoparticles in natural rubber latex as a potential wound dressing. International Journal of Biological Macromolecules, v. 211, 2022. 568?579| Biblioteca(s): Embrapa Instrumentação. |
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| 4. | | ABDALLA G.; MUSSAGY, C. U.; BRASIL, G. S. P.; SCONTRI, M.; SASAKI, J. C. S.; SU, Y.; BEBBER, C.; ROCHA, R. R.; ABREU, A. P. S.; GONÇALVES, R. P.; BURD, B. S.; PACHECO, M. F.; ROMEIRA, K. M.; PICHELI, F. P.; GUERRA, N. B.; FARHADI, N.; FLORIANO, J. F.; FORSTER, S.; HE, S.; NGUYEN, H. T.; PEIRSMAN, A.; TIRPAKOV, Z.; HUANG, S.; DOKMECIi, M. R.; FERREIRA, E. S.; Santos, L. S. dos; PIAZZA, R. D.; MARQUES, R. F. C.; GOMÉZ, A.; JUCAUD, V.; LI, B.; AZEREDO, H. M. C. de; HERCULANO, R. D. Eco-sustainable coatings based on chitosan, pectin, and lemon essential oil nanoemulsion and their effect on strawberry preservation. International Journal of Biological Macromolecules, v. 249, 126016, 2023. 1 - 15| Biblioteca(s): Embrapa Instrumentação. |
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| Registros recuperados : 4 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Instrumentação. Para informações adicionais entre em contato com cnpdia.biblioteca@embrapa.br. |
Registro Completo
|
Biblioteca(s): |
Embrapa Instrumentação. |
|
Data corrente: |
20/06/2022 |
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Data da última atualização: |
20/06/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
BORGES, F. A.; DRAGO, B. C.; BAGGIO, L. O.; BARROS, N. R. de; BRASIL, G. S. P.; SCONTRI, M.; MUSSAGY, C. U.; RIBEIRO, M. C. S.; MILORI, D. M. B. P.; MORAIS, C. P. de; MARANGONI, B. S.; NICOLODELLI, G.; MECWAN, M.; MANDAL, K.; GUERRA, N. B.; MENEGATTI, C. R.; HERCULANO, R. D. |
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Afiliação: |
DEBORA MARCONDES BASTOS PEREIRA, CNPDIA. |
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Título: |
Metronidazole-loaded gold nanoparticles in natural rubber latex as a potential wound dressing. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
International Journal of Biological Macromolecules, v. 211, 2022. |
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Páginas: |
568?579 |
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ISSN: |
0141-8130 |
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DOI: |
https://doi.org/10.1016/j.ijbiomac.2022.05.025 |
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Idioma: |
Inglês |
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Conteúdo: |
Gold nanoparticles (AuNPs) have shown interesting properties and specific biofunctions, providing benefits and new opportunities for controlled release systems. In this research, we demonstrated the use of natural rubber latex (NRL) from Hevea brasiliensis as a carrier of AuNPs and the antibiotic metronidazole (MET). We prepared AuNP-MET-NRL and characterized by physicochemical, biological and in vitro release assays. The effect of AuNPs on MET release was evaluated using UV?Vis and Laser-Induced Breakdown Spectroscopy (LIBS) techniques. AuNPs synthesized by Turkevich and Frens method resulted in a spherical shape with diameters of 34.8 ± 5.5 nm. We verified that there was no emergence or disappearance of new vibrational bands. Qualitatively and quantitatively, we showed that the MET crystals dispersed throughout the NRL. The Young's modulus and elongation values at dressing rupture were in the range appropriate for human skin application. 64.70% of the AuNP-MET complex was released within 100 h, exhibiting a second-order exponential release profile. The LIBS technique allowed monitoring of the AuNP release, indicating the Au emission peak reduction at 267.57 nm over time. Moreover, the dressing displayed an excellent hemocompatibility and fibroblast cell viability. These results demonstrated that the AuNP-MET-NRL wound dressing is a promising approach for dermal applications |
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Palavras-Chave: |
Gold nanoparticles; LIBS; Sustained release. |
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Categoria do assunto: |
-- |
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Marc: |
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100 1 $aBORGES, F. A.
245 $aMetronidazole-loaded gold nanoparticles in natural rubber latex as a potential wound dressing.$h[electronic resource]
260 $c2022
300 $a568?579
520 $aGold nanoparticles (AuNPs) have shown interesting properties and specific biofunctions, providing benefits and new opportunities for controlled release systems. In this research, we demonstrated the use of natural rubber latex (NRL) from Hevea brasiliensis as a carrier of AuNPs and the antibiotic metronidazole (MET). We prepared AuNP-MET-NRL and characterized by physicochemical, biological and in vitro release assays. The effect of AuNPs on MET release was evaluated using UV?Vis and Laser-Induced Breakdown Spectroscopy (LIBS) techniques. AuNPs synthesized by Turkevich and Frens method resulted in a spherical shape with diameters of 34.8 ± 5.5 nm. We verified that there was no emergence or disappearance of new vibrational bands. Qualitatively and quantitatively, we showed that the MET crystals dispersed throughout the NRL. The Young's modulus and elongation values at dressing rupture were in the range appropriate for human skin application. 64.70% of the AuNP-MET complex was released within 100 h, exhibiting a second-order exponential release profile. The LIBS technique allowed monitoring of the AuNP release, indicating the Au emission peak reduction at 267.57 nm over time. Moreover, the dressing displayed an excellent hemocompatibility and fibroblast cell viability. These results demonstrated that the AuNP-MET-NRL wound dressing is a promising approach for dermal applications
653 $aGold nanoparticles
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653 $aSustained release
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