Data/hora: 26/05/2024 01:02:45

Biblioteca(s): 	Embrapa Pecuária Sudeste.	
Data corrente: 	28/09/2015	
Data da última atualização: 	15/03/2023	
Autoria: 	GROSSI, D. do; GRUPIONI, N. V.; BUZANSKAS, M. E.; PAZ, C. C. P. de; REGITANO, L. C. de A.; ALENCAR, M. M. de; SCHENKEL, F. S.; MUNARI, D. P.	
Afiliação: 	DANIELA DO AMARAL GROSSI, University of Guelph; NATALIA VINHAL GRUPIONI, UNESP/JABOTICABAL, SP.; MARCOS ELI BUZANSKAS, UNESP, JABOTICABAL, SP.; CLAUDIA CRISTINA PARO DE PAZ, USP, RIBEIRÃO PRETO, SP.; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; MAURICIO MELLO DE ALENCAR, CPPSE; FLÁVIO SCHRAMM SCHENKEL, University of Guelph; DANÍSIO PRADO MUNARI, UNESP, JABOTICABAL, SP.	
Título: 	Allele substitution effects of IGF1, GH and PIT1 markers on estimated breeding values for weight and reproduction traits in Canchim beef cattle.	
Ano de publicação: 	2015	
Fonte/Imprenta: 	Livestock Science, v. 180, p. 78-83, oct. 2015.	
DOI: 	https://doi.org/10.1016/j.livsci.2015.07.018	
Idioma: 	Inglês	
Conteúdo: 	The aim of this study was to evaluate the allele substitution effects of IGF1, GH and PIT1 markers on the estimated breeding values (EBVs) for birth (BW) and weaning weights (WW), weight at 12 (W12) and 18 (W18) months of age, weight (WFC) and age (AFC) at first calving, and scrotal circumference measured at 12 (SC12) and 18 (SC18) months of age in Canchim beef cattle. Maternal effects were considered for birth (BWmaternal) and weaning (WWmaternal) weight. Regression analyses were carried out considering the EBVs, obtained from multi-trait analyses, and the deviations for each allele studied (four alleles for the IGF1 markers and two for GH and PIT1 markers, respectively). According to the results obtained for IGF1, the substitution effect of the ?225? allele was significant (P?0.05) and presented higher EBVs for BW, BWmaternal, WW, W12, W18, and SC18; and lower EBVs for WWmaternal. The allele substitution effect observed for GH gene was significant (P?0.05) on EBVs for AFC and WFC. The ?Valine? allele was responsible for lower EBVs for AFC and higher EBVs for WFC. For the PIT1 gene, the substitution effect of the ?Hinf?? allele was significant (P?0.05) on the EBVs for WW, WWmaternal, AFC, and WFC, respectively. Important allele substitution effects were found for weight and reproduction traits in Canchim cattle. In general, markers on the IGF1 gene are related to higher EBVs for weight, while markers on the GH and PIT1 showed greater influence on the EBVs for age and weight at first calving. Adding molecular markers information on the selection process could result in increased genetic gains in Canchim cattle. Future studies using high-density genotyping platforms may contribute to our understanding of the effects of these genes on traits of economic importance in the Canchim breed.	
Palavras-Chave: 	Association analysis; Regression coefficient.	
Thesaurus Nal: 	animal breeding; beef cattle; quantitative trait loci.	
Categoria do assunto: 	G Melhoramento Genético	
Registro original: 	Embrapa Pecuária Sudeste (CPPSE)	
Exemplares: 	CPPSE - (23069-1) - UPC - AP - DD - PROCI-2015.00042 - GRO - 2015.00042 - DIS