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Registros recuperados : 25 | |
2. | | MONTASSIER, M. F. S.; BRENTANO, L.; RICHTZENHAIN, L. J.; OKINO, C. H.; MONTASSIER, H. J. Genetic diversity of partial S1 an N gene sequences of infectious bronckitis virus isolates from Brazil. Virus Reviews and Research, v. 15, supl. 1, p. 196, oct. 2010. Trabalho apresentado no NATIONAL MEETING OF VIROLOGY, 21.; MERCOSUL MEETING OF VIROLOGY, 5. Projeto/Plano de Ação: 03.09.01900-01. Biblioteca(s): Embrapa Suínos e Aves. |
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3. | | MONTASSIER, M. F. S.; BRENTANO, L.; RICHTZENHAIN, L. J.; MONTASSIER, H. J. Diversity in relevant epitopes of S1 glycoprotein and nucleocapsid (N) protein of Brazilian variants of infectious bronchitis virus. Virus Reviews and Research, v. 15, supl. 1, p. 196, oct. 2010. Trabalho apresentado no NATIONAL MEETING OF VIROLOGY, 21.; MERCOSUL MEETING OF VIROLOGY, 5. Projeto/Plano de Ação: 03.09.01900-01. Biblioteca(s): Embrapa Suínos e Aves. |
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5. | | SANTOS, I. L.; GIBERTONI, A. M.; MONTASSIER, M. de F. S.; OKINO, C. H.; MONTASSIER, H. J. Improvement of immunodiagnosis of avian infectious bronchitis virus (IBV) infection by the detection of IgM and IgG antibodies using a new recombinant nucleoprotein-based Elisa. In: WORLD´S POULTRY CONGRESS, 24., 2012, Salvador. Abstract... Salvador: WSPA, 2012. 1 CD-ROM. World's Poultry Science Journal, v. 68, supl. 1, 2012. Projeto/Plano de Ação: 05.11.11.002. Biblioteca(s): Embrapa Suínos e Aves. |
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6. | | SANTOS, I. L.; OKINO, C. H.; MONTASSIER, M. de F. S.; SILVA, K. R.; FERNANDO, F. S.; MONTASSIER, H. J. Immune-protection mechanisms against late challenge with avian infectious bronchitis vírus (IBV) induced by a single-dose of an attenuated vaccine in day-old chicks. In: WORLD´S POULTRY CONGRESS, 24., 2012, Salvador. Abstract... Salvador: WSPA, 2012. 1 CD-ROM. World's Poultry Science Journal, v. 68, supl. 1, 2012. Projeto/Plano de Ação: 05.11.11.002 Biblioteca(s): Embrapa Suínos e Aves. |
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8. | | OKINO, C. H.; MONTASSIER, M. de F. S.; SILVA, K. R.; FERNANDO, F. S.; BRENTANO, L.; MONTASSIER, H. J. Avian infectious bronchitis vírus (IBV): effect of vaccine doses on mucosal imune responses and protection after challenge in chickens. In: WORLD´S POULTRY CONGRESS, 24., 2012, Salvador. Abstract... Salvador: WSPA, 2012. 1 CD-ROM. World's Poultry Science Journal, v. 68, supl. 1, 2012. Projeto/Plano de Ação: 05.11.11.002. Biblioteca(s): Embrapa Suínos e Aves. |
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11. | | OKINO, C. H.; MORES, M. A. Z.; MONTASSIER, H. J.; MATTOS, G. L. M.; BRENTANO, L.; COLDEBELLA, A.; RITTERBUSCH, G. A.; ESTEVES, P. A.; TREVISOL, I. M. Primary and secondary mucosal immunity after challenge with Brazilian avian infectious bronchitis variant. Journal of the Brazilian Society for Virology, Ribeirão Preto, v. 19, 2014. Suppl. 2. Edição dos anais do 25º. Brazilian Congress of Virology e 9º. Mercosur Meeting of Virology, Ribeirão Preto, set./out, 2014. p. 52 Biblioteca(s): Embrapa Suínos e Aves. |
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12. | | LOPES, P. D.; OKINO, C. H.; FERNANDO, F. S.; PAVANI, C.; CASAGRANDE, V. M.; LOPEZ, R. F. V.; MONTASSIER, M. F. de; MONTASSIER, H. J. Inactivated infectious bronchitis virus vaccine encapsulated in chitosan nanoparticles induces mucosal immune responses and effective protection against challenge. Vaccine, v. 36, p. 2630-2636, abr. 2018. 36 Biblioteca(s): Embrapa Pecuária Sudeste. |
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13. | | OKINO, C. H.; ALESSI, A. C.; MONTASSIER, M. de F. S.; ROSA, A. J. de M.; WANG, X.; MONTASSIER, H. J. Humoral and Cell-Mediated Immune Responses to Different Doses of Attenuated Vaccine Against Avian Infectious Bronchitis Virus. Viral Immunology, Nova York, v. 26, n. 4, p. 1-9, 2013. Biblioteca(s): Embrapa Cerrados; Embrapa Suínos e Aves. |
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14. | | FERNANDO, F. S.; OKINO, C. H.; SILVA, K. R.; FERNANDES, C. C.; GONÇALVES, M. C. M.; MONTASSIER, M. F. S.; VASCONCELOS, R. O.; MONTASSIER, H. J. Increased expression of Interleukin-6 related to nephritis in chickens challenged with an Avian infectious bronchitis virus variant. Pesquisa Veterinária Brasileira, Brasília, DF, v. 35, n. 3, p. 216-222, mar. 2015. Biblioteca(s): Embrapa Unidades Centrais. |
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15. | | LOPES, P. D.; OKINO, C. H.; FERNANDO, F. S.; PAVANI, C.; MARIGUELA, V. C.; MONTASSIER, M. DE F. S.; MONTASSIER, H. J. Comparative evaluation of immune responses and protection of chitosan nanoparticles and oil-emulsion adjuvants in avian coronavirus inactivated vaccines in chickens. Vaccines, v.9, n.12, 1457, 2021. Biblioteca(s): Embrapa Pecuária Sudeste. |
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16. | | OKINO, C. H.; MALAGO JUNIOR, W.; MARCONDES, C. R.; GIGLIOTI, R.; MONTASSIER, H. J.; OLIVEIRA, H. N. DE; OLIVEIRA, M. C. de S. CD4 bovine gene: differential polymorphisms among cattle breeds and a new tool for rapid identification. Veterinary Immunology and Immunopathology, v. 251, sep. 2022, 110462. 18 p. Biblioteca(s): Embrapa Pecuária Sudeste. |
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17. | | MATTOS, G. L. M.; OKINO, C. H.; TREVISOL, I. M.; MORES, M. A. Z.; LOPES, L. dos S.; MONTASSIER, H. J. Avaliação da imunidade celular contra isolado de campo de vírus da bronquite infecciosa (VBI) das galinhas. In: ANAIS DA CONFERÊNCIA NACIONAL DE DEFESA AGROPECUÁRIA: Defesa agropecuária a serviço de um estado de excelência, 5, 2014, Florianópolis, SC. Anais... Concórdia: Embrapa Suínos e Aves, 2014. 1 CD-ROM. ISBN 978-85-68630-00-6. P. 353 Biblioteca(s): Embrapa Suínos e Aves. |
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18. | | BORZI, M. M.; MONTASSIER, M. F. S.; OLIVEIRA, E. S.; SILVA, K. R.; SILVA, F. S.; OKINO, C. H.; MONTASSIER, H. J.; REISCHAK, D.; MENDONÇA, A. de O. Cloned nucleoprotein (NP) gene of avian influenza virus for using as a positive control in syber green I real time RT-PCR (RRT-PCR). In: BRAZILIAN CONGRESS OF VIROLOGY, 23.; MERCOSUR MEETING OF VIROLOGY, 7., 2012, Foz do Iguaçu. Virus and Research? Foz do Iguaçu: SBV, 2012. p. 409. Journal of the Brazilian Society for Virology, v. 17, n. 2, suppl. 1, 2012. Projeto/Plano de Ação: 11.11.11.111. Biblioteca(s): Embrapa Suínos e Aves. |
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19. | | OKINO, C. H.; MORES, M. A. Z.; MATTOS, G. L. M.; ESTEVES, P. A.; BRENTANO, L.; MONTASSIER, H. J.; TREVISOL, I. M. Diferentes respostas imunes locais induzidas após desafio com isolados de campo brasileiros do vírus da bronquite infecciosa das galinhas. In: CONFERÊNCIA FACTA, 2014, Atibaia. [Anais...] Campinas: Fundação APINCO de Ciência e Tecnologia Avícolas, 2014. 1 CD-ROM. Biblioteca(s): Embrapa Suínos e Aves. |
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20. | | BORZI, M. M.; PIZA, V. T.; MONTASSIER, M. F. S.; MORA, A. G.; OKINO, C. H.; REISCHAK, D.; MENDONÇA, A.; MONTASSIER, H. J. Development of a microplate immunocapture (IC) RT-PCR assays for the detection of avian influenza virus (AIV) and infectious bronchitis virus (IBV). In: BRAZILIAN CONGRESS OF VIROLOGY, 23.; MERCOSUR MEETING OF VIROLOGY, 7., 2012, Foz do Iguaçu. Virus and Research? Foz do Iguaçu: SBV, 2012. p.468-469. Journal of the Brazilian Society for Virology, v. 17, n. 2, suppl. 1, 2012. Projeto/Plano de Ação: 11.11.11.111. Biblioteca(s): Embrapa Suínos e Aves. |
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Registros recuperados : 25 | |
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Registro Completo
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
Data corrente: |
28/08/2018 |
Data da última atualização: |
21/05/2019 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
OKINO, C. H.; MORES, M. A. Z.; TREVISOL, I. M.; COLDEBELLA, A.; MONTASSIER, H. J.; BRENTANO, L. |
Afiliação: |
CINTIA HIROMI OKINO, CPPSE; MARCOS ANTONIO ZANELLA MORES, CNPSA; IARA MARIA TREVISOL, CNPSA; ARLEI COLDEBELLA, CNPSA; Hélio José Montassier, UNESP; LIANA BRENTANO, CNPSA. |
Título: |
Early immune responses and development of pathogenesis of avian infectious bronchitis viruses with different virulence profiles. |
Ano de publicação: |
2017 |
Fonte/Imprenta: |
Plos One, v. 12, p. 1-17, fev. 2017. |
Volume: |
12 |
Páginas: |
1-17 |
Idioma: |
Inglês |
Conteúdo: |
Avian infectious bronchitis virus (IBV) primarily replicates in epithelial cells of the upper respiratory tract of chickens, inducing both morphological and immune modulatory changes. However, the association between the local immune responses induced by IBV and the mechanisms of pathogenesis has not yet been completely elucidated. This study compared the expression profile of genes related to immune responses in tracheal samples after challenge with two Brazilian field isolates (A and B) of IBV from the same genotype, associating these responses with viral replication and with pathological changes in trachea and kidney. We detected a suppressive effect on the early activation of TLR7 pathway, followed by lower expression levels of inflammatory related genes induced by challenge with the IBV B isolate when compared to the challenge with to the IBV A isolate. Cell-mediated immune (CMI) related genes presented also lower levels of expression in tracheal samples from birds challenged with B isolate at 1dpi. Increased viral load and a higher percentage of birds with relevant lesions were observed in both tracheal and renal samples from chickens exposed to challenge with IBV B isolate. This differential pattern of early immune responses developed after challenge with IBV B isolate, related to the downregulation of TLR7, leading to insufficient pro-inflammatory response and lower CMI responses, seem to have an association with a most severe renal lesion and an enhanced capability of replication of this isolate in chicken. MenosAvian infectious bronchitis virus (IBV) primarily replicates in epithelial cells of the upper respiratory tract of chickens, inducing both morphological and immune modulatory changes. However, the association between the local immune responses induced by IBV and the mechanisms of pathogenesis has not yet been completely elucidated. This study compared the expression profile of genes related to immune responses in tracheal samples after challenge with two Brazilian field isolates (A and B) of IBV from the same genotype, associating these responses with viral replication and with pathological changes in trachea and kidney. We detected a suppressive effect on the early activation of TLR7 pathway, followed by lower expression levels of inflammatory related genes induced by challenge with the IBV B isolate when compared to the challenge with to the IBV A isolate. Cell-mediated immune (CMI) related genes presented also lower levels of expression in tracheal samples from birds challenged with B isolate at 1dpi. Increased viral load and a higher percentage of birds with relevant lesions were observed in both tracheal and renal samples from chickens exposed to challenge with IBV B isolate. This differential pattern of early immune responses developed after challenge with IBV B isolate, related to the downregulation of TLR7, leading to insufficient pro-inflammatory response and lower CMI responses, seem to have an association with a most severe renal lesion and an enhanced capability ... Mostrar Tudo |
Thesagro: |
Bronquite; Frango. |
Thesaurus NAL: |
Bronchitis; Chickens; Infectious bronchitis; Infectious bronchitis virus. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/182004/1/Okino-PONE-2017.pdf
|
Marc: |
LEADER 02335naa a2200277 a 4500 001 2094609 005 2019-05-21 008 2017 bl uuuu u00u1 u #d 100 1 $aOKINO, C. H. 245 $aEarly immune responses and development of pathogenesis of avian infectious bronchitis viruses with different virulence profiles.$h[electronic resource] 260 $c2017 300 $a1-17 12 490 $v12 520 $aAvian infectious bronchitis virus (IBV) primarily replicates in epithelial cells of the upper respiratory tract of chickens, inducing both morphological and immune modulatory changes. However, the association between the local immune responses induced by IBV and the mechanisms of pathogenesis has not yet been completely elucidated. This study compared the expression profile of genes related to immune responses in tracheal samples after challenge with two Brazilian field isolates (A and B) of IBV from the same genotype, associating these responses with viral replication and with pathological changes in trachea and kidney. We detected a suppressive effect on the early activation of TLR7 pathway, followed by lower expression levels of inflammatory related genes induced by challenge with the IBV B isolate when compared to the challenge with to the IBV A isolate. Cell-mediated immune (CMI) related genes presented also lower levels of expression in tracheal samples from birds challenged with B isolate at 1dpi. Increased viral load and a higher percentage of birds with relevant lesions were observed in both tracheal and renal samples from chickens exposed to challenge with IBV B isolate. This differential pattern of early immune responses developed after challenge with IBV B isolate, related to the downregulation of TLR7, leading to insufficient pro-inflammatory response and lower CMI responses, seem to have an association with a most severe renal lesion and an enhanced capability of replication of this isolate in chicken. 650 $aBronchitis 650 $aChickens 650 $aInfectious bronchitis 650 $aInfectious bronchitis virus 650 $aBronquite 650 $aFrango 700 1 $aMORES, M. A. Z. 700 1 $aTREVISOL, I. M. 700 1 $aCOLDEBELLA, A. 700 1 $aMONTASSIER, H. J. 700 1 $aBRENTANO, L. 773 $tPlos One$gv. 12, p. 1-17, fev. 2017.
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Embrapa Pecuária Sudeste (CPPSE) |
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