Data/hora: 13/06/2024 18:18:58

Biblioteca(s): 	Embrapa Arroz e Feijão.	
Tipo da produção científica: 	Artigo em Periódico Indexado	
Circulação/Nível: 	A - 1	
Data corrente: 	11/04/2016	
Data da última atualização: 	11/04/2016	
Autoria: 	ALVES, N. E. G.; MEJIA, E. G. de; VASCONCELOS, C. M.; BASSINELLO, P. Z.; MARTINO, H. S. D.	
Afiliação: 	NATALIA ELIZABETH GALDINO ALVES, UFV; ELVIRA GONZALEZ DE MEJIA, UNIVERSITY OF ILLINOIS URBANA, Champaign; CHRISTIANE MILEIB VASCONCELOS, UNIVERSIDADE FEDERAL DE OURO PRETO; PRISCILA ZACZUK BASSINELLO, CNPAF; HERCIA STAMPINI DUARTE MARTINO, UFV.	
Título: 	Postharvest storage of Carioca bean (Phaseolus vulgaris L.) did not impair inhibition of inflammation in lipopolysaccharide-induced human THP-1 macrophage-like cells.	
Ano de publicação: 	2016	
Fonte/Imprenta: 	Journal of Functional Foods, 23, p. 154-166, 2016.	
ISSN: 	1756-4646	
DOI: 	10.1016/j.jff.2016.02.029	
Idioma: 	Inglês	
Conteúdo: 	Storage can affect the nutritional quality of common bean (Phaseolus vulgaris), but little is known about the postharvest effect of storage on inflammation. The aim of this work was to evaluate, in vitro, the effect of postharvest storage-time on inflammation by Carioca beans, Madreperola (MP) and Pontal (PO), stored (0, 3 and 6 months), cooked and subjected to pepsinpancreatin simulated gastrointestinal digestion.Anti-inflammatory potential was investigated in human THP-1 macrophage-like cells. Commercial storage time did not affect protein concentration, degree of hydrolysis, hydropathicity or antioxidant capacity. All PO hydrolysates reduced tumour necrosis factor-&#945; (TNF- &#945;) (31% on average). MP hydrolysates decreased interleukin 1&#946; (IL-1&#946;) (PO 0: 0.1 mg/mL, 20.7%; PO 0 and 6: 5 mg/mL, 24.8 and 48.2%, respectively) and prostaglandin E-2 (PGE-2) (PO 0: all concentrations, 18% on average; PO 6: 0.1 mg/mL, 18.6%). Carioca beans inhibited inflammation and commercial storage time did not impair physicochemical or biological properties.	
Palavras-Chave: 	Antioxidant capacity; Peptidio; Tempo de armazenamento.	
Thesagro: 	Antioxidante; Feijão; Hidrolise; Phaseolus vulgaris.	
Thesaurus Nal: 	Hydrolysates; Inflammation; Peptides; Storage time.	
Categoria do assunto: 	Q Alimentos e Nutrição Humana	
Registro original: 	Embrapa Arroz e Feijão (CNPAF)	
Exemplares: 	CNPAF - (34129-1) - UPC - AP - DD - 2016 -  - 2016 - DIS