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Registro Completo |
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Biblioteca(s): |
Embrapa Gado de Leite. |
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Data corrente: |
16/02/2016 |
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Data da última atualização: |
03/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
KIM, E. S.; SONSTEGARD, T. S.; SILVA, M. V. G. B.; GASBARRE, L. C.; TASSEL, C. P. V. |
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Afiliação: |
Eui-Soo Kim; Tad S. Sonstegard; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; Louis C. Gasbarre; Curtis P. Van Tassell. |
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Título: |
Genome-wide scan of gastrointestinal nematode resistance in closed Angus population selected for minimized influence of MHC. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
PLoS One, v. 10, n. 3, : e0119380, 2015. |
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Páginas: |
18 p. |
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Idioma: |
Inglês |
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Conteúdo: |
Genetic markers associated with parasite indicator traits are ideal targets for study of marker assisted selection aimed at controlling infections that reduce herd use of anthelminthics. For this study, we collected gastrointestinal (GI) nematode fecal egg count (FEC) data from post-weaning animals of an Angus resource population challenged to a 26 week natural exposure on pasture. In all, data from 487 animals was collected over a 16 year period between 1992 and 2007, most of which were selected for a specific DRB1 allele to reduce the influence of potential allelic variant effects of the MHC locus. A genome-wide association study (GWAS) based on BovineSNP50 genotypes revealed six genomic regions located on bovine Chromosomes 3, 5, 8, 15 and 27; which were significantly associated (-log10 p=4.3) with Box-Cox transformed mean FEC (BC-MFEC). DAVID analysis of the genes within the significant genomic regions suggested a correlation between our results and annotation for genes involved in inflammatory response to infection. Furthermore, ROH and selection signature analyses provided strong evidence that the genomic regions associated BC-MFEC have not been affected by local autozygosity or recent experimental selection. These findings provide useful information for parasite resistance prediction for young grazing cattle and suggest new candidate gene targets for development of disease-modifying therapies or future studies of host response to GI parasite infection. |
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Thesaurus Nal: |
cattle; genetic markers; heritability. |
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Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/139139/1/Cnpgl-2015-PlosOne-Genome-wide.pdf
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Marc: |
LEADER 02131naa a2200217 a 4500
001 2037193
005 2024-02-03
008 2015 bl uuuu u00u1 u #d
100 1 $aKIM, E. S.
245 $aGenome-wide scan of gastrointestinal nematode resistance in closed Angus population selected for minimized influence of MHC.$h[electronic resource]
260 $c2015
300 $a18 p.
520 $aGenetic markers associated with parasite indicator traits are ideal targets for study of marker assisted selection aimed at controlling infections that reduce herd use of anthelminthics. For this study, we collected gastrointestinal (GI) nematode fecal egg count (FEC) data from post-weaning animals of an Angus resource population challenged to a 26 week natural exposure on pasture. In all, data from 487 animals was collected over a 16 year period between 1992 and 2007, most of which were selected for a specific DRB1 allele to reduce the influence of potential allelic variant effects of the MHC locus. A genome-wide association study (GWAS) based on BovineSNP50 genotypes revealed six genomic regions located on bovine Chromosomes 3, 5, 8, 15 and 27; which were significantly associated (-log10 p=4.3) with Box-Cox transformed mean FEC (BC-MFEC). DAVID analysis of the genes within the significant genomic regions suggested a correlation between our results and annotation for genes involved in inflammatory response to infection. Furthermore, ROH and selection signature analyses provided strong evidence that the genomic regions associated BC-MFEC have not been affected by local autozygosity or recent experimental selection. These findings provide useful information for parasite resistance prediction for young grazing cattle and suggest new candidate gene targets for development of disease-modifying therapies or future studies of host response to GI parasite infection.
650 $acattle
650 $agenetic markers
650 $aheritability
700 1 $aSONSTEGARD, T. S.
700 1 $aSILVA, M. V. G. B.
700 1 $aGASBARRE, L. C.
700 1 $aTASSEL, C. P. V.
773 $tPLoS One$gv. 10, n. 3, : e0119380, 2015.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Soja. Para informações adicionais entre em contato com valeria.cardoso@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Soja. |
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Data corrente: |
15/12/2020 |
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Data da última atualização: |
16/12/2020 |
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Tipo da produção científica: |
Artigo em Anais de Congresso |
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Autoria: |
SOUZA, E. M. G.; MARIN, D. R.; MOLINARI, M. D. C.; MARIN, S. R. R.; MERTZ-HENNING, L. M.; NEPOMUCENO, A. L. |
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Afiliação: |
Centro Universitário Filadelfia, UNIFIL, Londrina-PR.; Centro Universitário Filadelfia, UNIFIL, Londrina-PR.; Pós-doutoranda, Embrapa Soja; SILVANA REGINA ROCKENBACH MARIN, CNPSO; LILIANE MARCIA MERTZ HENNING, CNPSO; ALEXANDRE LIMA NEPOMUCENO, CNPSO. |
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Título: |
Análise in silico de genes NAC diferencialmente expressos em cultivares de soja sob déficit hídrico. |
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Ano de publicação: |
2020 |
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Fonte/Imprenta: |
In: JORNADA ACADÊMICA DA EMBRAPA SOJA, 15., 2020, Londrina. Resumos expandidos... Londrina: Embrapa Soja, 2020. 244 p. (Embrapa Soja. Documentos, 429). |
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Páginas: |
p. 90-99 |
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Série: |
(Embrapa Soja. Documentos, 429). |
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Idioma: |
Português |
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Notas: |
Artigo de acesso aberto. |
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Palavras-Chave: |
Déficit hídrico; Silico. |
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Thesagro: |
Análise; Balanço Hídrico; Gene; Soja. |
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Thesaurus NAL: |
Cultivars; Soil water deficit; Soybeans. |
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Categoria do assunto: |
F Plantas e Produtos de Origem Vegetal |
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Marc: |
LEADER 00991nam a2200301 a 4500
001 2128210
005 2020-12-16
008 2020 bl uuuu u00u1 u #d
100 1 $aSOUZA, E. M. G.
245 $aAnálise in silico de genes NAC diferencialmente expressos em cultivares de soja sob déficit hídrico.$h[electronic resource]
260 $aIn: JORNADA ACADÊMICA DA EMBRAPA SOJA, 15., 2020, Londrina. Resumos expandidos... Londrina: Embrapa Soja, 2020. 244 p. (Embrapa Soja. Documentos$c2020
300 $ap. 90-99
490 $a(Embrapa Soja. Documentos, 429).
500 $aArtigo de acesso aberto.
650 $aCultivars
650 $aSoil water deficit
650 $aSoybeans
650 $aAnálise
650 $aBalanço Hídrico
650 $aGene
650 $aSoja
653 $aDéficit hídrico
653 $aSilico
700 1 $aMARIN, D. R.
700 1 $aMOLINARI, M. D. C.
700 1 $aMARIN, S. R. R.
700 1 $aMERTZ-HENNING, L. M.
700 1 $aNEPOMUCENO, A. L.
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Embrapa Soja (CNPSO) |
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