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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agricultura Digital. Para informações adicionais entre em contato com cnptia.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Gado de Leite. |
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Data corrente: |
13/02/2017 |
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Data da última atualização: |
07/01/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ROSSE, I. C.; ASSIS, J. G.; OLIVEIRA, F. S.; LEITE, L. R.; ARAUJO, F.; ZERLOTINI NETO, A.; VOLPINI, A.; DOMINITINI, A. J.; LOPES, B. C.; ARBEX, W. A.; MACHADO, M. A.; PEIXOTO, M. G. C. D.; VERNEQUE, R. da S.; MARTINS, M. F.; COIMBRA, R. S.; SILVA, M. V. G. B.; OLIVEIRA, G.; CARVALHO, M. R. S. |
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Afiliação: |
IZINARA C. ROSSE, UFMG; JULIANA G. ASSIS, UFMG; Fiocruz; FRANCISLON S. OLIVEIRA, UFMG; Fiocruz; LAURA R. LEITE, UFMG; Fiocruz; FLÁVIO ARAUJO, Fiocruz; ADHEMAR ZERLOTINI NETO, CNPTIA; ANGELA VOLPINI, Fiocruz; ANDERSON J. DOMINITINI, Fiocruz; BEATRIZ C. LOPES, Epamig; WAGNER ANTONIO ARBEX, CNPGL; MARCO ANTONIO MACHADO, CNPGL; MARIA GABRIELA CAMPOLINA D PEIXOTO, CNPGL; RUI DA SILVA VERNEQUE, CNPGL; MARTA FONSECA MARTINS, CNPGL; RONEY S. COIMBRA, Fiocruz; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; GUILHERME OLIVEIRA, Fiocruz; Vale Technology Institute, Belém; MARIA RAQUEL S. CARVALHO, UFMG. |
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Título: |
Whole genome sequencing of Guzera cattle reveals genetic variants in candidate genes for production, disease resistance, and heat tolerance. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Mammalian Genome, v. 28, n. 1-2, p. 66-80, 2017. |
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ISBN: |
10.1007/s00335-016-9670-7 |
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Idioma: |
Inglês |
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Notas: |
Na publicação: Adhemar Zerlotini, Rui S. Verneque. |
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Conteúdo: |
Abstract In bovines, artificial selection has produced a large number of breeds which differ in production, environmental adaptation, and health characteristics. To investigate the genetic basis of these phenotypical differences, several bovine breeds have been sequenced. Millions of new SNVs were described at every new breed sequenced, suggesting that every breed should be sequenced. Guzerat or Guzera´ is an indicine breed resistant to drought and parasites that has been the base for some important breeds such as Brahman. Here, we describe the sequence of the Guzera´ genome and the in silico functional analyses of intragenic breed-specific variations. Matepaired libraries were generated using the ABI SOLiD system. Sequences were mapped to the Bos taurus reference genome (UMD 3.1) and 87% of the reference genome was covered at a 26X. Among the variants identified, 2,676,067 SNVs and 463,158 INDELs were homozygous, not found in any database searched, and may represent true differences between Guzera´ and B. taurus. Functional nalyses investigated with the NGS-SNP package focused on 1069 new, non-synonymous SNVs, splice-site variants (including acceptor and donor sites, and the conserved regions at both intron borders, referred to here as splice regions) and coding INDELs (NS/SS/I). These NS/SS/I map to 935 genes belonging to cell communication, environmental adaptation, signal transduction, sensory, and immune systems pathways. These pathways have been involved in phenotypes related to health, adaptation to the environment and behavior, and particularly, disease resistance and heat tolerance. Indeed, 105 of these genes are known QTLs for milk, meat and carcass, production, reproduction, and health traits. Therefore, in addition to describing new genetic variants, our approach provided groundwork for unraveling key candidate genes and mutations. MenosAbstract In bovines, artificial selection has produced a large number of breeds which differ in production, environmental adaptation, and health characteristics. To investigate the genetic basis of these phenotypical differences, several bovine breeds have been sequenced. Millions of new SNVs were described at every new breed sequenced, suggesting that every breed should be sequenced. Guzerat or Guzera´ is an indicine breed resistant to drought and parasites that has been the base for some important breeds such as Brahman. Here, we describe the sequence of the Guzera´ genome and the in silico functional analyses of intragenic breed-specific variations. Matepaired libraries were generated using the ABI SOLiD system. Sequences were mapped to the Bos taurus reference genome (UMD 3.1) and 87% of the reference genome was covered at a 26X. Among the variants identified, 2,676,067 SNVs and 463,158 INDELs were homozygous, not found in any database searched, and may represent true differences between Guzera´ and B. taurus. Functional nalyses investigated with the NGS-SNP package focused on 1069 new, non-synonymous SNVs, splice-site variants (including acceptor and donor sites, and the conserved regions at both intron borders, referred to here as splice regions) and coding INDELs (NS/SS/I). These NS/SS/I map to 935 genes belonging to cell communication, environmental adaptation, signal transduction, sensory, and immune systems pathways. These pathways have been involved in phenotypes ... Mostrar Tudo |
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Palavras-Chave: |
Diseases; Genome sequencing; Sequência genética. |
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Thesagro: |
Bos Indicus; Gado de corte. |
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Thesaurus Nal: |
breeding; dairy cattle; Genome; Zebu. |
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Categoria do assunto: |
--
L Ciência Animal e Produtos de Origem Animal |
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Marc: |
LEADER 03169naa a2200445 a 4500
001 2072807
005 2020-01-07
008 2017 bl uuuu u00u1 u #d
100 1 $aROSSE, I. C.
245 $aWhole genome sequencing of Guzera cattle reveals genetic variants in candidate genes for production, disease resistance, and heat tolerance.$h[electronic resource]
260 $c2017
500 $aNa publicação: Adhemar Zerlotini, Rui S. Verneque.
520 $aAbstract In bovines, artificial selection has produced a large number of breeds which differ in production, environmental adaptation, and health characteristics. To investigate the genetic basis of these phenotypical differences, several bovine breeds have been sequenced. Millions of new SNVs were described at every new breed sequenced, suggesting that every breed should be sequenced. Guzerat or Guzera´ is an indicine breed resistant to drought and parasites that has been the base for some important breeds such as Brahman. Here, we describe the sequence of the Guzera´ genome and the in silico functional analyses of intragenic breed-specific variations. Matepaired libraries were generated using the ABI SOLiD system. Sequences were mapped to the Bos taurus reference genome (UMD 3.1) and 87% of the reference genome was covered at a 26X. Among the variants identified, 2,676,067 SNVs and 463,158 INDELs were homozygous, not found in any database searched, and may represent true differences between Guzera´ and B. taurus. Functional nalyses investigated with the NGS-SNP package focused on 1069 new, non-synonymous SNVs, splice-site variants (including acceptor and donor sites, and the conserved regions at both intron borders, referred to here as splice regions) and coding INDELs (NS/SS/I). These NS/SS/I map to 935 genes belonging to cell communication, environmental adaptation, signal transduction, sensory, and immune systems pathways. These pathways have been involved in phenotypes related to health, adaptation to the environment and behavior, and particularly, disease resistance and heat tolerance. Indeed, 105 of these genes are known QTLs for milk, meat and carcass, production, reproduction, and health traits. Therefore, in addition to describing new genetic variants, our approach provided groundwork for unraveling key candidate genes and mutations.
650 $abreeding
650 $adairy cattle
650 $aGenome
650 $aZebu
650 $aBos Indicus
650 $aGado de corte
653 $aDiseases
653 $aGenome sequencing
653 $aSequência genética
700 1 $aASSIS, J. G.
700 1 $aOLIVEIRA, F. S.
700 1 $aLEITE, L. R.
700 1 $aARAUJO, F.
700 1 $aZERLOTINI NETO, A.
700 1 $aVOLPINI, A.
700 1 $aDOMINITINI, A. J.
700 1 $aLOPES, B. C.
700 1 $aARBEX, W. A.
700 1 $aMACHADO, M. A.
700 1 $aPEIXOTO, M. G. C. D.
700 1 $aVERNEQUE, R. da S.
700 1 $aMARTINS, M. F.
700 1 $aCOIMBRA, R. S.
700 1 $aSILVA, M. V. G. B.
700 1 $aOLIVEIRA, G.
700 1 $aCARVALHO, M. R. S.
773 $tMammalian Genome$gv. 28, n. 1-2, p. 66-80, 2017.
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Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
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Biblioteca |
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Registro Completo
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Biblioteca(s): |
Embrapa Mandioca e Fruticultura. |
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Data corrente: |
09/09/2015 |
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Data da última atualização: |
14/03/2016 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
MARCILIO, H. de C.; RAMOS, M. J. M.; AMORIM, E. P.; SILVA, E. C. da; SANTOS, C. C. dos. |
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Afiliação: |
HUMBERTO DE CARVALHO MARCILIO, EMPAER-MT; MARIA JOSÉ MOTA RAMOS; EDSON PERITO AMORIM, CNPMF; ELDER CASSIMIRO DA SILVA; CIRO CERCINO DOS SANTOS. |
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Título: |
Avaliação de genótipos de bananeira na região Sudoeste do Estado de Mato Grosso. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
In: CONGRESSO LATINO-AMERICANO E DO CARIBE DE BANANAS E PLÁTANOS, 3., 2015. Corupá. Musáceas no subtrópico: desafios e oportunidades frente à variabilidade climática. Corupá, SC: Rede da America Latina e Caribe para a Pesquisa e Desenvolvimento da Banana - MUSALAC, 2015. |
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Idioma: |
Português |
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Conteúdo: |
O ataque dos fungos constituem os maiores problemas da bananicultura mundial merecendo destaque o mal-do-Panamá e a Sigatoka negra, sendo que a maioria das cultivares de bananeira utilizada pelos agricultores é susceptível às estas doenças. As características fenológicas da planta podem variar em função dos genótipos utilizados, apresentando maior ou menor crescimento e desenvolvimento vegetativo, e influenciando nos tratos culturais, fitossanitários, no tombamento de plantas e na colheita. Neste trabalho o objetivo foi avaliar o desempenho agronômico de cultivares de bananeiras resistentes e suscetíveis à Sigatoka negra no sudoeste de Mato Grosso. |
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Palavras-Chave: |
Plant disease. |
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Thesagro: |
Banana; Doença de planta; Mal do Panamá. |
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Categoria do assunto: |
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/129288/1/Avaliacao-de-Genotipos.pdf
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Marc: |
LEADER 01508nam a2200205 a 4500
001 2023553
005 2016-03-14
008 2015 bl uuuu u00u1 u #d
100 1 $aMARCILIO, H. de C.
245 $aAvaliação de genótipos de bananeira na região Sudoeste do Estado de Mato Grosso.$h[electronic resource]
260 $aIn: CONGRESSO LATINO-AMERICANO E DO CARIBE DE BANANAS E PLÁTANOS, 3., 2015. Corupá. Musáceas no subtrópico: desafios e oportunidades frente à variabilidade climática. Corupá, SC: Rede da America Latina e Caribe para a Pesquisa e Desenvolvimento da Banana - MUSALAC$c2015
520 $aO ataque dos fungos constituem os maiores problemas da bananicultura mundial merecendo destaque o mal-do-Panamá e a Sigatoka negra, sendo que a maioria das cultivares de bananeira utilizada pelos agricultores é susceptível às estas doenças. As características fenológicas da planta podem variar em função dos genótipos utilizados, apresentando maior ou menor crescimento e desenvolvimento vegetativo, e influenciando nos tratos culturais, fitossanitários, no tombamento de plantas e na colheita. Neste trabalho o objetivo foi avaliar o desempenho agronômico de cultivares de bananeiras resistentes e suscetíveis à Sigatoka negra no sudoeste de Mato Grosso.
650 $aBanana
650 $aDoença de planta
650 $aMal do Panamá
653 $aPlant disease
700 1 $aRAMOS, M. J. M.
700 1 $aAMORIM, E. P.
700 1 $aSILVA, E. C. da
700 1 $aSANTOS, C. C. dos
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Embrapa Mandioca e Fruticultura (CNPMF) |
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