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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
01/08/1992 |
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Data da última atualização: |
30/06/2023 |
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Autoria: |
NARAYAN, O.; CLEMENTS, J. E.; STRANDBERG, J. D.; CORK, L. C.; GRIFFIN, D. E. |
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Título: |
Biological characterization of the virus causing leukoencephalitis and arthritis in goats. |
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Ano de publicação: |
1980 |
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Fonte/Imprenta: |
The Journal of General Virology, v. 50, n. 1, p. 69-79, Sep. 1980. |
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DOI: |
10.1099/0022-1317-50-1-69. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: This study describes the Biological properties of a strain of virus isolated from tissues of a goat with leukoencephalomyelitis-arthritis. The agent is a retrovirus, having a virion-associated reverse transcriptase enzyme and an antigenic determinant(s) which cross-reacts with the p30 of visna-maedi viruses. Morphogenesis of the virus is also similar to visna virus in terms of virus assembly and the multinucleated giant cell formation which accompanies replication of the latter virus. Despite its cytopathogenic property the goat agent was not lytic in goat cell culture, causing instead a productive infection which persisted through multiple subcultures of the cells. The virus replicated incompletely in sheep cell cultures but could be rescued from the latter, weeks after inoculation, by co-cultivation with goat cells. Our data suggest that this strain of goat leukoencephalitis virus is a variant of the ovine retroviruses with a host range limited to the goat. |
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Palavras-Chave: |
Leucocephalite. |
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Thesagro: |
Artrite; Caprino; Doença. |
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Thesaurus Nal: |
Antigens; Encephalitis; Goat diseases; Goats; Immunology; Retroviridae; Visna maedi virus. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 01856naa a2200313 a 4500
001 1521726
005 2023-06-30
008 1980 bl uuuu u00u1 u #d
024 7 $a10.1099/0022-1317-50-1-69.$2DOI
100 1 $aNARAYAN, O.
245 $aBiological characterization of the virus causing leukoencephalitis and arthritis in goats.$h[electronic resource]
260 $c1980
520 $aAbstract: This study describes the Biological properties of a strain of virus isolated from tissues of a goat with leukoencephalomyelitis-arthritis. The agent is a retrovirus, having a virion-associated reverse transcriptase enzyme and an antigenic determinant(s) which cross-reacts with the p30 of visna-maedi viruses. Morphogenesis of the virus is also similar to visna virus in terms of virus assembly and the multinucleated giant cell formation which accompanies replication of the latter virus. Despite its cytopathogenic property the goat agent was not lytic in goat cell culture, causing instead a productive infection which persisted through multiple subcultures of the cells. The virus replicated incompletely in sheep cell cultures but could be rescued from the latter, weeks after inoculation, by co-cultivation with goat cells. Our data suggest that this strain of goat leukoencephalitis virus is a variant of the ovine retroviruses with a host range limited to the goat.
650 $aAntigens
650 $aEncephalitis
650 $aGoat diseases
650 $aGoats
650 $aImmunology
650 $aRetroviridae
650 $aVisna maedi virus
650 $aArtrite
650 $aCaprino
650 $aDoença
653 $aLeucocephalite
700 1 $aCLEMENTS, J. E.
700 1 $aSTRANDBERG, J. D.
700 1 $aCORK, L. C.
700 1 $aGRIFFIN, D. E.
773 $tThe Journal of General Virology$gv. 50, n. 1, p. 69-79, Sep. 1980.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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