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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Gado de Leite; Embrapa Pecuária Sudeste. |
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Data corrente: |
17/12/2014 |
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Data da última atualização: |
05/02/2024 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
MOKRY, F. B.; BUZANSKAS, M. E.; MUDADU, M. de A.; GROSSI, D. do A.; HIGA, R. H.; VENTURA, R. V.; LIMA, A. O. de; SARGOLZAEI, M.; MEIRELLES, S. L. C.; SCHENKEL, F. S.; SILVA, M. V. G. B.; NICIURA, S. C. M.; ALENCAR, M. M. de; MINARI, D. P.; REGITANO, L. C. de A. |
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Afiliação: |
MARCOS VINICIUS GUALBERTO B SILVA, CNPGL. |
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Título: |
Linkage disequilibrium and haplotype block structure in a composite beef cattle breed. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
BMC Genomics, London v. 15, S6, p. 1-9, 2014. |
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DOI: |
10.1186/1471-2164-15-S7-S6 |
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Idioma: |
Inglês |
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Notas: |
Suppl 7. |
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Conteúdo: |
Abstract. Background: The development of linkage disequilibrium (LD) maps and the characterization of haplotype block structure at the population level are useful parameters for guiding genome wide association (GWA) studies, and for understanding the nature of non-linear association between phenotypes and genes. The elucidation of haplotype block structure can reduce the information of several single nucleotide polymorphisms (SNP) into the information of a haplotype block, reducing the number of SNPs in a coherent way for consideration in GWA and genomic selection studies. Results: The maximum average LD, measured by r2 varied between 0.33 to 0.40 at a distance of < 2.5 kb, and the minimum average values of r2 varied between 0.05 to 0.07 at distances ranging from 400 to 500 kb, clearly showing that the average r2 reduced with the increase in SNP pair distances. The persistence of LD phase showed higher values at shorter genomic distances, decreasing with the increase in physical distance, varying from 0.96 at a distance of < 2.5 kb to 0.66 at a distance from 400 to 500 kb. A total of 78% of all SNPs were clustered into haplotype blocks, covering 1,57 Mb of the total autosomal genome size. Conclusions: This study presented the first high density linkage disequilibrium map and haplotype block structure for a composite beef cattle population, and indicates that the high density SNP panel over 700 k can be used for genomic selection implementation and GWA studies for Canchim beef cattle. MenosAbstract. Background: The development of linkage disequilibrium (LD) maps and the characterization of haplotype block structure at the population level are useful parameters for guiding genome wide association (GWA) studies, and for understanding the nature of non-linear association between phenotypes and genes. The elucidation of haplotype block structure can reduce the information of several single nucleotide polymorphisms (SNP) into the information of a haplotype block, reducing the number of SNPs in a coherent way for consideration in GWA and genomic selection studies. Results: The maximum average LD, measured by r2 varied between 0.33 to 0.40 at a distance of < 2.5 kb, and the minimum average values of r2 varied between 0.05 to 0.07 at distances ranging from 400 to 500 kb, clearly showing that the average r2 reduced with the increase in SNP pair distances. The persistence of LD phase showed higher values at shorter genomic distances, decreasing with the increase in physical distance, varying from 0.96 at a distance of < 2.5 kb to 0.66 at a distance from 400 to 500 kb. A total of 78% of all SNPs were clustered into haplotype blocks, covering 1,57 Mb of the total autosomal genome size. Conclusions: This study presented the first high density linkage disequilibrium map and haplotype block structure for a composite beef cattle population, and indicates that the high density SNP panel over 700 k can be used for genomic selection implementation and GWA studies for Canchim bee... Mostrar Tudo |
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Palavras-Chave: |
Composite; Desequilíbrio de ligação; Genome wide association studies; Halplotype block; Linjage disequilibirium; Polimorfismo de nucleotídeo único. |
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Thesagro: |
Gado de corte. |
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Thesaurus Nal: |
Beef cattle; Linkage disequilibrium; Single nucleotide polymorphism. |
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Categoria do assunto: |
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/119863/1/MOKRY.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/114007/1/PROCI-2104.00140.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/114252/1/1471-2164-15-S7-S6.pdf
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Marc: |
LEADER 02809naa a2200433 a 4500
001 2006604
005 2024-02-05
008 2014 bl uuuu u00u1 u #d
024 7 $a10.1186/1471-2164-15-S7-S6$2DOI
100 1 $aMOKRY, F. B.
245 $aLinkage disequilibrium and haplotype block structure in a composite beef cattle breed.$h[electronic resource]
260 $c2014
500 $aSuppl 7.
520 $aAbstract. Background: The development of linkage disequilibrium (LD) maps and the characterization of haplotype block structure at the population level are useful parameters for guiding genome wide association (GWA) studies, and for understanding the nature of non-linear association between phenotypes and genes. The elucidation of haplotype block structure can reduce the information of several single nucleotide polymorphisms (SNP) into the information of a haplotype block, reducing the number of SNPs in a coherent way for consideration in GWA and genomic selection studies. Results: The maximum average LD, measured by r2 varied between 0.33 to 0.40 at a distance of < 2.5 kb, and the minimum average values of r2 varied between 0.05 to 0.07 at distances ranging from 400 to 500 kb, clearly showing that the average r2 reduced with the increase in SNP pair distances. The persistence of LD phase showed higher values at shorter genomic distances, decreasing with the increase in physical distance, varying from 0.96 at a distance of < 2.5 kb to 0.66 at a distance from 400 to 500 kb. A total of 78% of all SNPs were clustered into haplotype blocks, covering 1,57 Mb of the total autosomal genome size. Conclusions: This study presented the first high density linkage disequilibrium map and haplotype block structure for a composite beef cattle population, and indicates that the high density SNP panel over 700 k can be used for genomic selection implementation and GWA studies for Canchim beef cattle.
650 $aBeef cattle
650 $aLinkage disequilibrium
650 $aSingle nucleotide polymorphism
650 $aGado de corte
653 $aComposite
653 $aDesequilíbrio de ligação
653 $aGenome wide association studies
653 $aHalplotype block
653 $aLinjage disequilibirium
653 $aPolimorfismo de nucleotídeo único
700 1 $aBUZANSKAS, M. E.
700 1 $aMUDADU, M. de A.
700 1 $aGROSSI, D. do A.
700 1 $aHIGA, R. H.
700 1 $aVENTURA, R. V.
700 1 $aLIMA, A. O. de
700 1 $aSARGOLZAEI, M.
700 1 $aMEIRELLES, S. L. C.
700 1 $aSCHENKEL, F. S.
700 1 $aSILVA, M. V. G. B.
700 1 $aNICIURA, S. C. M.
700 1 $aALENCAR, M. M. de
700 1 $aMINARI, D. P.
700 1 $aREGITANO, L. C. de A.
773 $tBMC Genomics, London$gv. 15, S6, p. 1-9, 2014.
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Registro original: |
Embrapa Gado de Leite (CNPGL) |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Recursos Genéticos e Biotecnologia. Para informações adicionais entre em contato com cenargen.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
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Data corrente: |
27/05/1997 |
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Data da última atualização: |
01/06/2005 |
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Autoria: |
GUERRA, W. D.; MAGALHAES, B. P. |
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Afiliação: |
EMBRAPA-CENARGEN. |
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Título: |
Inimigos naturais do gafanhoto Rhammatocerus schistocercoides (Orthoptera: acrididae) em Mato Grosso. |
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Ano de publicação: |
1996 |
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Fonte/Imprenta: |
In: SIMPOSIO DE CONTROLE BIOLOGICO, 5., 1996, Foz do Iguacu, PR. Anais: sessao de posters. Londrina: EMBRAPA-CNPSO, 1996. |
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Páginas: |
p.446. |
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Idioma: |
Português |
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Palavras-Chave: |
Grasshopper; Orthoptera: Acrididae; Rhamatocerus schistocercoides. |
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Thesagro: |
Controle Biológico; Gafanhoto; Inimigo Natural. |
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Thesaurus NAL: |
biological control; natural enemies. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 00737nam a2200217 a 4500
001 1171318
005 2005-06-01
008 1996 bl uuuu u01u1 u #d
100 1 $aGUERRA, W. D.
245 $aInimigos naturais do gafanhoto Rhammatocerus schistocercoides (Orthoptera$bacrididae) em Mato Grosso.
260 $aIn: SIMPOSIO DE CONTROLE BIOLOGICO, 5., 1996, Foz do Iguacu, PR. Anais: sessao de posters. Londrina: EMBRAPA-CNPSO$c1996
300 $ap.446.
650 $abiological control
650 $anatural enemies
650 $aControle Biológico
650 $aGafanhoto
650 $aInimigo Natural
653 $aGrasshopper
653 $aOrthoptera: Acrididae
653 $aRhamatocerus schistocercoides
700 1 $aMAGALHAES, B. P.
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Registro original: |
Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
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