Data/hora: 05/06/2024 15:25:56

Biblioteca(s): 	Embrapa Agroindústria de Alimentos.	
Tipo da produção científica: 	Artigo em Periódico Indexado	
Circulação/Nível: 	A - 1	
Data corrente: 	11/05/2023	
Data da última atualização: 	13/12/2023	
Autoria: 	MISHIMA, M. D. V.; MARTINO, H. S. D.; KOLBA, N.; SHAH, D. D.; GRANCIERI, M.; SANTOS, K. M. O. dos; LIMA, J. P.; SILVA, B. P. DA; GONZALEZ DE MEJIA, E.; TAKO, E.	
Afiliação: 	MARCELLA DUARTE VILLAS MISHIMA, Cornell University; HÉRCIA STAMPINO DUARTE MARTINO, UNIVERSIDADE FEDERAL DE VIÇOSA; NIKOLAI KOLBA, Cornell University; DRASHTI DHIRENKUMAR SHAH, Cornell University; MARIANA GRANCIERI, UNIVERSIDADE FEDERAL DE VIÇOSA; KARINA MARIA OLBRICH DOS SANTOS, CTAA; JANINE PASSOS LIMA, CTAA; BÁRBARA PEREIRA DA SILVA, UNIVERSIDADE FEDERAL DE VIÇOSA; ELVIRA GONZALEZ DE MEJIA, University of Illinois at Urbana-Champaign; ELAD TAKO, Cornell University.	
Título: 	Effects of Intra-Amniotic Administration of the Hydrolyzed Protein of Chia (Salvia hispanica L.) and Lacticaseibacillus paracasei on Intestinal Functionality, Morphology, and Bacterial Populations, In Vivo (Gallus gallus).	
Ano de publicação: 	2023	
Fonte/Imprenta: 	Nutrients, v. 15, n. 8, p. 1831-15, 2023.	
Páginas: 	17 p.	
DOI: 	https://doi.org/10.3390/nu15081831	
Idioma: 	Inglês	
Conteúdo: 	As a protein source, chia contains high concentrations of bioactive peptides. Probiotics support a healthy digestive tract and immune system. Our study evaluated the effects of the intra-amniotic administration of the hydrolyzed chia protein and the probiotic Lacticaseibacillus paracasei on intestinal bacterial populations, the intestinal barrier, the inflammatory response, and brush border membrane functionality in ovo (Gallus gallus). Fertile broiler (Gallus gallus) eggs (n = 9/group) were divided into 5 groups: (NI) non-injected; (H2O) 18 M? H2O; (CP) 10 mg/mL hydrolyzed chia protein; (CPP) 10 mg/mL hydrolyzed chia protein + 106 colony-forming unit (CFU) L. paracasei; (P) 106 CFU L. paracasei. The intra-amniotic administration was performed on day 17 of incubation. At hatching (day 21), the animals were euthanized, and the duodenum and cecum content were collected. The probiotic downregulated the gene expression of NF-??, increased Lactobacillus and E. coli, and reduced Clostridium populations. The hydrolyzed chia protein downregulated the gene expression of TNF-?, increased OCLN, MUC2, and aminopeptidase, reduced Bifidobacterium, and increased Lactobacillus. The three experimental groups improved in terms of intestinal morphology. The current results suggest that the intra-amniotic administration of the hydrolyzed chia protein or a probiotic promoted positive changes in terms of the intestinal inflammation, barrier, and morphology, improving intestinal health.	
Palavras-Chave: 	Bioactive peptides; Chia seed; Gut health; In vivo; Intestinal barrier; Microbiota; Probiotic.	
Thesaurus Nal: 	Inflammation.	
Categoria do assunto: 	--	
Registro original: 	Embrapa Agroindústria de Alimentos (CTAA)	
Exemplares: 	CTAA - (15482-1) - UPC - AP - DD -  -  -  - DIS