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Registro Completo |
Biblioteca(s): |
Embrapa Agroindústria de Alimentos; Embrapa Amazônia Ocidental. |
Data corrente: |
04/04/2013 |
Data da última atualização: |
14/12/2017 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
AZEVEDO, M. M. B.; CHAVES, F. C. M.; ALMEIDA, C. A.; BIZZO, H. R.; DUARTE, R. S.; CAMPOS-TAKAKI, G. M.; ALVIANO, C. S.; ALVIANO, D. S. |
Afiliação: |
Mariana M. B. Azevedo, UFRJ; FRANCISCO CELIO MAIA CHAVES, CPAA; Catia A. Almeida, IMPG-UFRJ; HUMBERTO RIBEIRO BIZZO, CTAA; Rafael S. Duarte, IMPG-UFRJ; Galba M. Campos-Takaki, Catholic University of Pernambuco; Celuta S. Alviano, IMPG-UFRJ; Daniela S. Alviano, IMPG-UFRJ. |
Título: |
Antioxidant and Antimicrobial Activities of 7-Hydroxy-calamenene-Rich Essential Oils from Croton cajucara Benth. |
Ano de publicação: |
2013 |
Fonte/Imprenta: |
Molecules, v. 18, n. 1, p. 1128-1137, jan. 2013. |
ISSN: |
1420-3049 |
DOI: |
10.3390/molecules18011128 |
Idioma: |
Inglês |
Conteúdo: |
Croton cajucara is a shrub native to the Amazon region locally known as ?sacaca?. Two morphotypes are known: white and red ?sacaca?. The essential oils (EO) obtained by hydrodistillation from leaves of the red morphotype were, in general, rich in 7-hydroxycalamenene (28.4%?37.5%). The effectiveness of these EO regarding the antimicrobial activity against pathogenic microorganisms was initially investigated by the drop test method, showing significant inhibition zones. Among the microorganisms tested, the essential oils rich in 7-hydroxycalamenene were more effective against methicillin resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Mycobacterium tuberculosis, M. smegmatis, Mucor circinelloides and Rhizopus oryzae. The minimum inhibitory concentrations (MIC) of the oils were determined using the broth dilution assay. It was possible to observe that 7-hydroxycalamenene-rich oils presented high antimicrobial activity, with MIC of 4.76 × 10−3 μg/mL for MRSA, 4.88 μg/mL for M. tuberculosis, 39.06 μg/mL for M. smegmatis, and 0.152 μg/mL for R. oryzae and 3.63 × 10−8 μg/mL for M. circinelloides. The antioxidant activity of this EO suggests that 7-hydroxycalamenene provides more antioxidant activity according with EC50 less than 63.59 μg/mL. Considering the bioactive potential of EOs and 7-hydroxycalamenene could be of great interest for development of antimicrobials for therapeutic use in treatment of bacterial and fungal infections in humans and/or veterinary practice. MenosCroton cajucara is a shrub native to the Amazon region locally known as ?sacaca?. Two morphotypes are known: white and red ?sacaca?. The essential oils (EO) obtained by hydrodistillation from leaves of the red morphotype were, in general, rich in 7-hydroxycalamenene (28.4%?37.5%). The effectiveness of these EO regarding the antimicrobial activity against pathogenic microorganisms was initially investigated by the drop test method, showing significant inhibition zones. Among the microorganisms tested, the essential oils rich in 7-hydroxycalamenene were more effective against methicillin resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Mycobacterium tuberculosis, M. smegmatis, Mucor circinelloides and Rhizopus oryzae. The minimum inhibitory concentrations (MIC) of the oils were determined using the broth dilution assay. It was possible to observe that 7-hydroxycalamenene-rich oils presented high antimicrobial activity, with MIC of 4.76 × 10−3 μg/mL for MRSA, 4.88 μg/mL for M. tuberculosis, 39.06 μg/mL for M. smegmatis, and 0.152 μg/mL for R. oryzae and 3.63 × 10−8 μg/mL for M. circinelloides. The antioxidant activity of this EO suggests that 7-hydroxycalamenene provides more antioxidant activity according with EC50 less than 63.59 μg/mL. Considering the bioactive potential of EOs and 7-hydroxycalamenene could be of great interest for development of antimicrobials for therapeutic use in treatment of bacterial and fungal in... Mostrar Tudo |
Palavras-Chave: |
Atividade antimicrobiana; Atividade antioxidante; Óleos essenciais; Sacaca. |
Thesagro: |
Óleo Essencial. |
Thesaurus Nal: |
Croton cajucara. |
Categoria do assunto: |
-- X Pesquisa, Tecnologia e Engenharia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/80491/1/molecules-18-01128.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/88878/1/2013-060.pdf
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Marc: |
LEADER 02431naa a2200301 a 4500 001 1955000 005 2017-12-14 008 2013 bl uuuu u00u1 u #d 022 $a1420-3049 024 7 $a10.3390/molecules18011128$2DOI 100 1 $aAZEVEDO, M. M. B. 245 $aAntioxidant and Antimicrobial Activities of 7-Hydroxy-calamenene-Rich Essential Oils from Croton cajucara Benth. 260 $c2013 520 $aCroton cajucara is a shrub native to the Amazon region locally known as ?sacaca?. Two morphotypes are known: white and red ?sacaca?. The essential oils (EO) obtained by hydrodistillation from leaves of the red morphotype were, in general, rich in 7-hydroxycalamenene (28.4%?37.5%). The effectiveness of these EO regarding the antimicrobial activity against pathogenic microorganisms was initially investigated by the drop test method, showing significant inhibition zones. Among the microorganisms tested, the essential oils rich in 7-hydroxycalamenene were more effective against methicillin resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Mycobacterium tuberculosis, M. smegmatis, Mucor circinelloides and Rhizopus oryzae. The minimum inhibitory concentrations (MIC) of the oils were determined using the broth dilution assay. It was possible to observe that 7-hydroxycalamenene-rich oils presented high antimicrobial activity, with MIC of 4.76 × 10−3 μg/mL for MRSA, 4.88 μg/mL for M. tuberculosis, 39.06 μg/mL for M. smegmatis, and 0.152 μg/mL for R. oryzae and 3.63 × 10−8 μg/mL for M. circinelloides. The antioxidant activity of this EO suggests that 7-hydroxycalamenene provides more antioxidant activity according with EC50 less than 63.59 μg/mL. Considering the bioactive potential of EOs and 7-hydroxycalamenene could be of great interest for development of antimicrobials for therapeutic use in treatment of bacterial and fungal infections in humans and/or veterinary practice. 650 $aCroton cajucara 650 $aÓleo Essencial 653 $aAtividade antimicrobiana 653 $aAtividade antioxidante 653 $aÓleos essenciais 653 $aSacaca 700 1 $aCHAVES, F. C. M. 700 1 $aALMEIDA, C. A. 700 1 $aBIZZO, H. R. 700 1 $aDUARTE, R. S. 700 1 $aCAMPOS-TAKAKI, G. M. 700 1 $aALVIANO, C. S. 700 1 $aALVIANO, D. S. 773 $tMolecules$gv. 18, n. 1, p. 1128-1137, jan. 2013.
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Registro original: |
Embrapa Amazônia Ocidental (CPAA) |
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Registro Completo
Biblioteca(s): |
Embrapa Soja. |
Data corrente: |
05/04/2004 |
Data da última atualização: |
25/07/2005 |
Autoria: |
SILVA, J. F. V.; MOREIRA, M. A.; ARIAS, C. A. A.; ALMEIDA, A. M. R.; YORINORI, J. T.; KIIHL, R. A. de S. |
Título: |
Identificação de marcadores moleculares ligados a genes de resistência a doenças (04.2000.322-01). |
Ano de publicação: |
2003 |
Fonte/Imprenta: |
In: HOFFMANN-CAMPO, C. B.; SARAIVA, O. F. (Org.). Resultados de pesquisa da Embrapa Soja - 2002: ecofisiologia e biologia molecular. Londrina: Embrapa Soja, 2003. |
Páginas: |
p. 8-21. |
Série: |
(Embrapa Soja. Documentos, 217). |
Idioma: |
Português |
Conteúdo: |
Nematóide de cisto da soja (Heterodera glycines); Nematóide de galha ((Meloidogyne javanica); Mancha parda (Septoria glycines). |
Thesagro: |
Marcador Molecular; Soja. |
Categoria do assunto: |
-- |
Marc: |
LEADER 00913naa a2200229 a 4500 001 1466539 005 2005-07-25 008 2003 bl uuuu u00u1 u #d 100 1 $aSILVA, J. F. V. 245 $aIdentificação de marcadores moleculares ligados a genes de resistência a doenças (04.2000.322-01). 260 $c2003 300 $ap. 8-21. 490 $a(Embrapa Soja. Documentos, 217). 520 $aNematóide de cisto da soja (Heterodera glycines); Nematóide de galha ((Meloidogyne javanica); Mancha parda (Septoria glycines). 650 $aMarcador Molecular 650 $aSoja 700 1 $aMOREIRA, M. A. 700 1 $aARIAS, C. A. A. 700 1 $aALMEIDA, A. M. R. 700 1 $aYORINORI, J. T. 700 1 $aKIIHL, R. A. de S. 773 $tIn: HOFFMANN-CAMPO, C. B.; SARAIVA, O. F. (Org.). Resultados de pesquisa da Embrapa Soja - 2002: ecofisiologia e biologia molecular. Londrina: Embrapa Soja, 2003.
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