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Registro Completo |
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
18/12/2018 |
Data da última atualização: |
24/01/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
OTTO, P. I.; GUIMARÃES, S. E. F.; VERARDO, L. L.; AZEVEDO, A. L. S.; VANDENPLAS, J.; SOARES, A. C. C.; SEVILLANO, C. A.; VERONEZE R; PIRES, M. de F. A.; FREITAS, C. de; PRATA, M. C. de A.; FURLONG, J.; VERNEQUE, R. da S.; MARTINS, M. F.; PANETTO, J. C. do C.; CARVALHO, W. A.; GOBO, D. O. R.; SILVA, M. V. G. B.; MACHADO, M. A. |
Afiliação: |
PAMELA I. OTTO, UFV; SIMONE ELIZA FACIONI GUIMARAES, UFV; LUCAS L. VERARDO, UFV; ANA LUISA SOUSA AZEVEDO, CNPGL; J. VANDENPLAS, Wageningen University; ALINE C. C. SOARES, UFV; CLAUDIA A. SEVILLANO, Wageningen University; Topigs Norsvin Research Center, Beuningen; RENATA VERONEZE, UFV; MARIA DE FATIMA AVILA PIRES, CNPGL; CELIO DE FREITAS, CNPGL; MARCIA CRISTINA DE AZEVEDO PRATA, CNPGL; JOHN FURLONG, CNPGL; RUI DA SILVA VERNEQUE, CNPGL; MARTA FONSECA MARTINS, CNPGL; JOAO CLAUDIO DO CARMO PANETTO, CNPGL; WANESSA ARAUJO CARVALHO, CNPGL; DIEGO O. R. GOBO, UFV; MARCOS VINICIUS GUALBERTO B SILVA, CNPGL; MARCO ANTONIO MACHADO, CNPGL. |
Título: |
Genome-wide association studies for tick resistance in Bos taurus × Bos indicus crossbred cattle: A deeper look into this intricate mechanism. |
Ano de publicação: |
2018 |
Fonte/Imprenta: |
Journal of Dairy Science, v. 101, n. 12, p. 11020-11032, 2018. |
DOI: |
10.3168/jds.2017-14223 |
Idioma: |
Inglês |
Conteúdo: |
ABSTRACT Rhipicephalus (Boophilus) microplus is the main cattle ectoparasite in tropical areas. Gir × Holstein crossbred cows are well adapted to different production systems in Brazil. In this context, we performed genome-wide association study (GWAS) and post-GWAS analyses for R. microplus resistance in an experimental Gir × Holstein F2 population. Single nucleotide polymorphisms (SNP) identified in GWAS were used to build gene networks and to investigate the breed of origin for its alleles. Tick artificial infestations were performed during the dry and rainy seasons. Illumina BovineSNP50 BeadChip (Illumina Inc., San Diego, CA) and single-step BLUP procedure was used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene transcription factors networks, generated from enriched transcription factors, identified from the promoter sequences of selected gene sets. The genetic origin of marker alleles in the F2 population was assigned using the breed of origin of alleles approach. Heritability estimates for tick counts were 0.40 ± 0.11 in the rainy season and 0.54 ± 0.11 in the dry season. The top ten 0.5-Mbp windows with the highest percentage of genetic variance explained by SNP markers were found in chromosomes 10 and 23 for both the dry and rainy seasons. Gene network analyses allowed the identification of genes involved with biological processes relevant to immune system functions (TREM1, TREM2, and CD83). Gene-transcription factors network allowed the identification of genes involved with immune functions (MYO5A, TREML1, and PRSS16). In resistant animals, the average proportion of animals showing significant SNPs with paternal and maternal alleles originated from Gir breed was 44.8% whereas the proportion of animals with both paternal and maternal alleles originated from Holstein breed was 11.3%. Susceptible animals showing both paternal and maternal alleles originated from Holstein breed represented 44.6% on average, whereas both paternal and maternal alleles originated from Gir breed animals represented 9.3%. This study allowed us to identify candidate genes for tick resistance in Gir × Holstein crossbreds in both rainy and dry seasons. According to the origin of alleles analysis, we found that most animals classified as resistant showed 2 alleles from Gir breed, while the susceptible ones showed alleles from Holstein. Based on these results, the identified genes may be thoroughly investigated in additional experiments aiming to validate their effects on tick resistance phenotype in cattle. MenosABSTRACT Rhipicephalus (Boophilus) microplus is the main cattle ectoparasite in tropical areas. Gir × Holstein crossbred cows are well adapted to different production systems in Brazil. In this context, we performed genome-wide association study (GWAS) and post-GWAS analyses for R. microplus resistance in an experimental Gir × Holstein F2 population. Single nucleotide polymorphisms (SNP) identified in GWAS were used to build gene networks and to investigate the breed of origin for its alleles. Tick artificial infestations were performed during the dry and rainy seasons. Illumina BovineSNP50 BeadChip (Illumina Inc., San Diego, CA) and single-step BLUP procedure was used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene transcription factors networks, generated from enriched transcription factors, identified from the promoter sequences of selected gene sets. The genetic origin of marker alleles in the F2 population was assigned using the breed of origin of alleles approach. Heritability estimates for tick counts were 0.40 ± 0.11 in the rainy season and 0.54 ± 0.11 in the dry season. The top ten 0.5-Mbp windows with the highest percentage of genetic variance explained by SNP markers were found in chromosomes 10 and 23 for both the dry and rainy seasons. Gene network analyses allowed the identification of genes involved with biological processes relevant to immune system functions (TREM1, TREM2, and CD83). Gene-transcription factors network a... Mostrar Tudo |
Palavras-Chave: |
Breed of origin; Gene network; Gir × Holstein crossbred. |
Thesaurus Nal: |
Genetic variance. |
Categoria do assunto: |
L Ciência Animal e Produtos de Origem Animal |
Marc: |
LEADER 03793naa a2200397 a 4500 001 2101869 005 2023-01-24 008 2018 bl uuuu u00u1 u #d 024 7 $a10.3168/jds.2017-14223$2DOI 100 1 $aOTTO, P. I. 245 $aGenome-wide association studies for tick resistance in Bos taurus × Bos indicus crossbred cattle$bA deeper look into this intricate mechanism.$h[electronic resource] 260 $c2018 520 $aABSTRACT Rhipicephalus (Boophilus) microplus is the main cattle ectoparasite in tropical areas. Gir × Holstein crossbred cows are well adapted to different production systems in Brazil. In this context, we performed genome-wide association study (GWAS) and post-GWAS analyses for R. microplus resistance in an experimental Gir × Holstein F2 population. Single nucleotide polymorphisms (SNP) identified in GWAS were used to build gene networks and to investigate the breed of origin for its alleles. Tick artificial infestations were performed during the dry and rainy seasons. Illumina BovineSNP50 BeadChip (Illumina Inc., San Diego, CA) and single-step BLUP procedure was used for GWAS. Post-GWAS analyses were performed by gene ontology terms enrichment and gene transcription factors networks, generated from enriched transcription factors, identified from the promoter sequences of selected gene sets. The genetic origin of marker alleles in the F2 population was assigned using the breed of origin of alleles approach. Heritability estimates for tick counts were 0.40 ± 0.11 in the rainy season and 0.54 ± 0.11 in the dry season. The top ten 0.5-Mbp windows with the highest percentage of genetic variance explained by SNP markers were found in chromosomes 10 and 23 for both the dry and rainy seasons. Gene network analyses allowed the identification of genes involved with biological processes relevant to immune system functions (TREM1, TREM2, and CD83). Gene-transcription factors network allowed the identification of genes involved with immune functions (MYO5A, TREML1, and PRSS16). In resistant animals, the average proportion of animals showing significant SNPs with paternal and maternal alleles originated from Gir breed was 44.8% whereas the proportion of animals with both paternal and maternal alleles originated from Holstein breed was 11.3%. Susceptible animals showing both paternal and maternal alleles originated from Holstein breed represented 44.6% on average, whereas both paternal and maternal alleles originated from Gir breed animals represented 9.3%. This study allowed us to identify candidate genes for tick resistance in Gir × Holstein crossbreds in both rainy and dry seasons. According to the origin of alleles analysis, we found that most animals classified as resistant showed 2 alleles from Gir breed, while the susceptible ones showed alleles from Holstein. Based on these results, the identified genes may be thoroughly investigated in additional experiments aiming to validate their effects on tick resistance phenotype in cattle. 650 $aGenetic variance 653 $aBreed of origin 653 $aGene network 653 $aGir × Holstein crossbred 700 1 $aGUIMARÃES, S. E. F. 700 1 $aVERARDO, L. L. 700 1 $aAZEVEDO, A. L. S. 700 1 $aVANDENPLAS, J. 700 1 $aSOARES, A. C. C. 700 1 $aSEVILLANO, C. A. 700 1 $aVERONEZE R 700 1 $aPIRES, M. de F. A. 700 1 $aFREITAS, C. de 700 1 $aPRATA, M. C. de A. 700 1 $aFURLONG, J. 700 1 $aVERNEQUE, R. da S. 700 1 $aMARTINS, M. F. 700 1 $aPANETTO, J. C. do C. 700 1 $aCARVALHO, W. A. 700 1 $aGOBO, D. O. R. 700 1 $aSILVA, M. V. G. B. 700 1 $aMACHADO, M. A. 773 $tJournal of Dairy Science$gv. 101, n. 12, p. 11020-11032, 2018.
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Embrapa Gado de Leite (CNPGL) |
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Biblioteca(s): |
Embrapa Amazônia Oriental. |
Data corrente: |
17/01/2018 |
Data da última atualização: |
22/12/2021 |
Tipo da produção científica: |
Artigo em Anais de Congresso |
Autoria: |
LIMA, I. V. de; SILVA, M. B. da; ADAMI, M.; PINHEIRO, A. F.; BARROS, M. N. R.; NARVAES, I. da S.; GOMES, A. R.; WATRIN, O. dos S.; MAGNO JÚNIOR, P. S. do L.; ROCHA, E. S. da. |
Afiliação: |
Ingrid Vieira de Lima, INPE-CRA; Murilo Brasil da Silva, INPE-CRA; MARCOS ADAMI, INPE-CRA; Alcione Ferreira Pinheiro, INPE-CRA; Márcia Nazaré Rodrigues Barros, INPE-CRA; Igor da Silva Narvaes, INPE-CRA; Alessandra Rodrigues Gomes, INPE-CRA; ORLANDO DOS SANTOS WATRIN, CPATU; Paulo Sérgio do L. Magno Júnior, UFRA; Eduardo Saraiva da Rocha, UFRA. |
Título: |
Dinâmica das áreas de reflorestamento no município de Paragominas, Estado do Pará, considerando dados temporais do projeto TerraClass. |
Ano de publicação: |
2017 |
Fonte/Imprenta: |
In: SIMPÓSIO BRASILEIRO DE SENSORIAMENTO REMOTO, 18., 2017, Santos. Anais... São José dos Campos: INPE, 2017. |
Páginas: |
p. 6694-6701. |
Idioma: |
Português |
Conteúdo: |
The municipality of Paragominas is considered a model among the municipalities of the "Legal Amazon", being the inspiration for the program "Municipios verdes", because it was through him and other public policies that the municipality managed to leave the list of municipalities that more Deforested and has been showing an expansion of reforestation practice. This study aims to analyze the dynamics of land use and occupation in the municipality of Paragominas, from 2008 to 2014, with emphasis on reforested areas in the municipality, using maps with land use and land cover data derived from remote sensing and Geoprocessing. The results indicated that although Paragominas faced an apparent consolidated situation in relation to the dynamics of land use, it continues to suffer a huge loss of forest resources. However, this municipality also showed a high conversion of pasture fields to agriculture, forest plantations or regrowth areas. Despite being a region apparently consolidated in terms of space exploration, Paragominas continues to suffer a great loss of forest resources, which can be seen in the gradual increase of the areas of use, the changes in the areas destined to reforestation projects came from the increase of the planted areas And the diversity of plant species. |
Palavras-Chave: |
Dinâmica da paisagem; Geotecnologia; Paragominas. |
Thesagro: |
Reflorestamento. |
Thesaurus NAL: |
Amazonia. |
Categoria do assunto: |
Z Localizações Geográficas |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/171257/1/galoa-proceedings-sbsr-59760-dinamica-das-are.pdf
|
Marc: |
LEADER 02246nam a2200289 a 4500 001 2085676 005 2021-12-22 008 2017 bl uuuu u00u1 u #d 100 1 $aLIMA, I. V. de 245 $aDinâmica das áreas de reflorestamento no município de Paragominas, Estado do Pará, considerando dados temporais do projeto TerraClass.$h[electronic resource] 260 $aIn: SIMPÓSIO BRASILEIRO DE SENSORIAMENTO REMOTO, 18., 2017, Santos. Anais... São José dos Campos: INPE$c2017 300 $ap. 6694-6701. 520 $aThe municipality of Paragominas is considered a model among the municipalities of the "Legal Amazon", being the inspiration for the program "Municipios verdes", because it was through him and other public policies that the municipality managed to leave the list of municipalities that more Deforested and has been showing an expansion of reforestation practice. This study aims to analyze the dynamics of land use and occupation in the municipality of Paragominas, from 2008 to 2014, with emphasis on reforested areas in the municipality, using maps with land use and land cover data derived from remote sensing and Geoprocessing. The results indicated that although Paragominas faced an apparent consolidated situation in relation to the dynamics of land use, it continues to suffer a huge loss of forest resources. However, this municipality also showed a high conversion of pasture fields to agriculture, forest plantations or regrowth areas. Despite being a region apparently consolidated in terms of space exploration, Paragominas continues to suffer a great loss of forest resources, which can be seen in the gradual increase of the areas of use, the changes in the areas destined to reforestation projects came from the increase of the planted areas And the diversity of plant species. 650 $aAmazonia 650 $aReflorestamento 653 $aDinâmica da paisagem 653 $aGeotecnologia 653 $aParagominas 700 1 $aSILVA, M. B. da 700 1 $aADAMI, M. 700 1 $aPINHEIRO, A. F. 700 1 $aBARROS, M. N. R. 700 1 $aNARVAES, I. da S. 700 1 $aGOMES, A. R. 700 1 $aWATRIN, O. dos S. 700 1 $aMAGNO JÚNIOR, P. S. do L. 700 1 $aROCHA, E. S. da
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