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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital. |
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Data corrente: |
03/02/2015 |
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Data da última atualização: |
22/01/2020 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
SOUZA, M. M.; ZERLOTINI, A.; TIZIOTO, P. C.; OLIVEIRA, P. S. N.; SOMAVILLA, A. L.; MOKRY, F. B.; CESAR, A. S. M.; DINIZ, W. J. S.; MUDADU, M. A.; NICIURA, S. C. M.; COUTINHO, L. L.; REGITANO, L. C. A. |
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Afiliação: |
UFSCar; ADHEMAR ZERLOTINI NETO, CNPTIA; UFSCar; UFSCar; Unesp; USP; UFSCar; MAURICIO DE ALVARENGA MUDADU, CPPSE; SIMONE CRISTINA MEO NICIURA, CPPSE; USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
Complex pattern of CAST allelic expression in bovine muscle tissue. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
In: ANNUAL INTERNATIONAL CONFERENCE ON INTELLIGENT SYSTEMS FOR MOLECULAR BIOLOGY, 22., 2014, Boston, USA. Program... [Boston]: International Society for Computational Biology, 2014. |
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Páginas: |
Não paginado. |
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Idioma: |
Inglês |
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Notas: |
ISMB 2014. Pôster E13. |
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Palavras-Chave: |
Bioinformática; Polimorfismo de nucleotídeo único. |
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Thesaurus Nal: |
Bioinformatics; Single nucleotide polymorphism. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/117949/1/complex-souza.pdf
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Marc: |
LEADER 01041nam a2200301 a 4500
001 2007540
005 2020-01-22
008 2014 bl uuuu u00u1 u #d
100 1 $aSOUZA, M. M.
245 $aComplex pattern of CAST allelic expression in bovine muscle tissue.$h[electronic resource]
260 $aIn: ANNUAL INTERNATIONAL CONFERENCE ON INTELLIGENT SYSTEMS FOR MOLECULAR BIOLOGY, 22., 2014, Boston, USA. Program... [Boston]: International Society for Computational Biology$c2014
300 $aNão paginado.
500 $aISMB 2014. Pôster E13.
650 $aBioinformatics
650 $aSingle nucleotide polymorphism
653 $aBioinformática
653 $aPolimorfismo de nucleotídeo único
700 1 $aZERLOTINI, A.
700 1 $aTIZIOTO, P. C.
700 1 $aOLIVEIRA, P. S. N.
700 1 $aSOMAVILLA, A. L.
700 1 $aMOKRY, F. B.
700 1 $aCESAR, A. S. M.
700 1 $aDINIZ, W. J. S.
700 1 $aMUDADU, M. A.
700 1 $aNICIURA, S. C. M.
700 1 $aCOUTINHO, L. L.
700 1 $aREGITANO, L. C. A.
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Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
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Registro Completo
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
30/06/2010 |
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Data da última atualização: |
18/11/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
FERREIRA, C. R.; BURGSTALLER, J. P.; PERECIN, F.; GARCIA, J. M.; CHIARATTI, M. R.; MÉO, S. C.; MULLER, M.; SMITH, L. C.; MEIRELLES, F. V.; STEINBORN, R. |
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Afiliação: |
CHRISTINA RAMIRES FERREIRA, UNESP-JABOTICABAL; JORG PATRICK BURGSTALLER, UNIVERSTIY OF VETERINARY MEDICINE - VIENNA; FELIPE PERECIN, UNESP - JABOTICABAL; JOAQUIM MANSANO GARCIA, UNESP - JABOTICABAL; MARCOS ROBERTO CHIARATTI, USP - PIRASSUNUNGA; SIMONE CRISTINA MÉO, CPPSE; MATHIAS MULLER, UNIVERSITY OF VETERINARY MEDICINE - VIENNA; LAWRENCE CHARLES SMITH, UNIVERSITE DE MONTREAL - QUEBEC; FLÁVIO VIEIRA MEIRELLES, USP - PIRASSUNUNGA; RALF STEINBORN, UNIVERSITY OF VETERINARY MEDICINE - VIENNA. |
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Título: |
Pronounced segregation of donor mitochondria introduced by bovine Ooplasmic tranfer to the female germ-line. |
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Ano de publicação: |
2010 |
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Fonte/Imprenta: |
Biology of Reproduction, v. 82, n. 03, p. 563-571, mar. 2010. |
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DOI: |
https://doi.org/10.1095/biolreprod.109.080564 |
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Idioma: |
Inglês |
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Conteúdo: |
Ooplasmic transfer (01) has been used in basic mouse research for studying lhe segregation of mtDNA, as well as in human assisted reproduction for improving embryo development in cases of persistent developmental failure. Using cattle as a large-animal model, we demonstrate that lhe moderate amount of mitochondria introduced by OT is transmitted to lhe offspring's oocytes; e.g., modifies lhe germ fine. The danar mtDNA was detectable in 25% and 65% of oocytes collected from two females. Its high variation in heteroplasmic oocytes, ranging from 1.1% to 33.5% and from 0.4% to 15.5%, can be explained by random genetic drift in lhe female germ line. Centrifugation-mediated enrichment of mitochondria il1 lhe pole zone of lhe recipient zygote's ooplasm and its substitution by danar ooplasm led to elevated proportions of danar mtDNA in reconstructed zygotes compared with zygotes produced by standard OT (23.6% :!: 9.6% versus 12.1% :!: 4.5%; P <0.0001). We also characterized lhe proliferation of mitochondria from lhe OT parents-the recipient zygote (Bos primigenius taurus type) and lhe danar ooplasm (B. primigenius indicus type). Regression analysis performed for 57 tissue samples collected from lhe seven OT fetuses at different points during fetal development found a decreasing proportion of donor mt DNA (r2=0.78). This indicates a preferred proliferation of recipient of the OT recipeint expressinf a B. primigenius indicus phenotype. |
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Palavras-Chave: |
Bovine; Developmental biology; Embryo; Gamete biology; Ooplasmic. |
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Thesagro: |
DNA. |
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Categoria do assunto: |
G Melhoramento Genético |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/28805/1/PROCISCMN2010.00002.pdf
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Marc: |
LEADER 02370naa a2200313 a 4500
001 1856388
005 2022-11-18
008 2010 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1095/biolreprod.109.080564$2DOI
100 1 $aFERREIRA, C. R.
245 $aPronounced segregation of donor mitochondria introduced by bovine Ooplasmic tranfer to the female germ-line.$h[electronic resource]
260 $c2010
520 $aOoplasmic transfer (01) has been used in basic mouse research for studying lhe segregation of mtDNA, as well as in human assisted reproduction for improving embryo development in cases of persistent developmental failure. Using cattle as a large-animal model, we demonstrate that lhe moderate amount of mitochondria introduced by OT is transmitted to lhe offspring's oocytes; e.g., modifies lhe germ fine. The danar mtDNA was detectable in 25% and 65% of oocytes collected from two females. Its high variation in heteroplasmic oocytes, ranging from 1.1% to 33.5% and from 0.4% to 15.5%, can be explained by random genetic drift in lhe female germ line. Centrifugation-mediated enrichment of mitochondria il1 lhe pole zone of lhe recipient zygote's ooplasm and its substitution by danar ooplasm led to elevated proportions of danar mtDNA in reconstructed zygotes compared with zygotes produced by standard OT (23.6% :!: 9.6% versus 12.1% :!: 4.5%; P <0.0001). We also characterized lhe proliferation of mitochondria from lhe OT parents-the recipient zygote (Bos primigenius taurus type) and lhe danar ooplasm (B. primigenius indicus type). Regression analysis performed for 57 tissue samples collected from lhe seven OT fetuses at different points during fetal development found a decreasing proportion of donor mt DNA (r2=0.78). This indicates a preferred proliferation of recipient of the OT recipeint expressinf a B. primigenius indicus phenotype.
650 $aDNA
653 $aBovine
653 $aDevelopmental biology
653 $aEmbryo
653 $aGamete biology
653 $aOoplasmic
700 1 $aBURGSTALLER, J. P.
700 1 $aPERECIN, F.
700 1 $aGARCIA, J. M.
700 1 $aCHIARATTI, M. R.
700 1 $aMÉO, S. C.
700 1 $aMULLER, M.
700 1 $aSMITH, L. C.
700 1 $aMEIRELLES, F. V.
700 1 $aSTEINBORN, R.
773 $tBiology of Reproduction$gv. 82, n. 03, p. 563-571, mar. 2010.
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Embrapa Pecuária Sudeste (CPPSE) |
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