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| 7. |  | FRONZA, C. F.; ANSELMO, J.; MARQUES, J. L. B.; PINTARELLI, G. B.; CASTRO, A. de. A Blower-like approach to predict the effectiveness of vaccines in a TB dynamic. International Journal of Engineering Research and Applications, Delhi, v. 4, n. 6, p. 233-238, June 2014.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 8. | | CASTRO, A. de; FRONZA, C. F.; GIACHETTO, P. F.; ALVES, D. Influence of antigenic mutations in time evolution of the immune memory - a dynamic modeling. Lecture Notes in Computer Science, v. 5676, p. 133-142. Proceedings of the 4th Brazilian Symposium on Bioinformatics, 2009, held in Porto Alegre, Brazil, in July 2009.| Biblioteca(s): Embrapa Agricultura Digital. |
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| 9. | | CASTRO, A. de; FRONZA, C. F.; HERAI, R. H.; ALVES, D. Evidence of deterministic evolution in the immunological memory process. In: INTERNATIONAL SYMPOSIUM ON MATHEMATICAL AND COMPUTATIONAL BIOLOGY, 9., 2009, Brasília, DF. Proceedings... Brasília, DF: BIOMAT Institute for Advanced Studies of Biosystems, 2009. p. 1-14.| Biblioteca(s): Embrapa Agricultura Digital. |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Agricultura Digital. Para informações adicionais entre em contato com cnptia.biblioteca@embrapa.br. |
Registro Completo
|
Biblioteca(s): |
Embrapa Agricultura Digital. |
|
Data corrente: |
08/01/2010 |
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Data da última atualização: |
15/01/2020 |
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Tipo da produção científica: |
Artigo em Anais de Congresso / Nota Técnica |
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Autoria: |
CASTRO, A. de; FRONZA, C. F.; HERAI, R. H.; ALVES, D. |
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Afiliação: |
ALEXANDRE DE CASTRO, CNPTIA; CARLOS F. FRONZA, Unifesp; ROBERTO HIROCHI HERAI, IB/Unicamp; DOMINGOS ALVES, USP. |
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Título: |
Evidence of deterministic evolution in the immunological memory process. |
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Ano de publicação: |
2009 |
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Fonte/Imprenta: |
In: INTERNATIONAL SYMPOSIUM ON MATHEMATICAL AND COMPUTATIONAL BIOLOGY, 9., 2009, Brasília, DF. Proceedings... Brasília, DF: BIOMAT Institute for Advanced Studies of Biosystems, 2009. |
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Páginas: |
p. 1-14. |
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DOI: |
10.1142/9789814304900_0004 |
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Idioma: |
Inglês |
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Conteúdo: |
In this paper, we study the behavior of immune memory against antigenic mutation. Using a dynamic model proposed by one of the authors in a previous study, we have performed simulations of several inoculations, where in each virtual sample the viral population undergo mutations. Our results suggest that the sustainability of the immunizations is dependent on viral variability and that the memory lifetimes are not random, what condradicts what was suggested by Tarlinton et al.. We show that what may cause an apparent random behavior of the immune memory is the antigenic variability. |
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Palavras-Chave: |
Evolução determinística; Memória imunológica; Mutação antigênica. |
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Thesagro: |
Mutação. |
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Thesaurus NAL: |
Memory; Mutation. |
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Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
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Marc: |
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008 2009 bl uuuu u00u1 u #d
024 7 $a10.1142/9789814304900_0004$2DOI
100 1 $aCASTRO, A. de
245 $aEvidence of deterministic evolution in the immunological memory process.$h[electronic resource]
260 $aIn: INTERNATIONAL SYMPOSIUM ON MATHEMATICAL AND COMPUTATIONAL BIOLOGY, 9., 2009, Brasília, DF. Proceedings... Brasília, DF: BIOMAT Institute for Advanced Studies of Biosystems$c2009
300 $ap. 1-14.
520 $aIn this paper, we study the behavior of immune memory against antigenic mutation. Using a dynamic model proposed by one of the authors in a previous study, we have performed simulations of several inoculations, where in each virtual sample the viral population undergo mutations. Our results suggest that the sustainability of the immunizations is dependent on viral variability and that the memory lifetimes are not random, what condradicts what was suggested by Tarlinton et al.. We show that what may cause an apparent random behavior of the immune memory is the antigenic variability.
650 $aMemory
650 $aMutation
650 $aMutação
653 $aEvolução determinística
653 $aMemória imunológica
653 $aMutação antigênica
700 1 $aFRONZA, C. F.
700 1 $aHERAI, R. H.
700 1 $aALVES, D.
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Embrapa Agricultura Digital (CNPTIA) |
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