Data/hora: 06/06/2024 13:30:31

Biblioteca(s): 	Embrapa Unidades Centrais.	
Data corrente: 	13/09/2017	
Data da última atualização: 	13/09/2017	
Autoria: 	CAVALCANTI, L. C. G.; MORAES, J. C. F.; FARIA, D. A. de; McMANUS, C. M.; NEPOMUCENO, A. R.; SOUZA, C. J. H. de; CAETANO, A. R.; PAIVA, S. R.	
Afiliação: 	Lilian Cristina Gomes Cavalcanti; José Carlos Ferrugem Moraes; Danielle Asis de Faria; Concepta Margaret McManus; Alcebiades Renato Nepomuceno; Carlos José Hoff de Souza; Alexandre Rodrigues Caetano; Samuel Rezende Paiva.	
Título: 	Genetic characterization of coat color genes in Brazilian Crioula sheep from a conservation nucleus.	
Ano de publicação: 	2017	
Fonte/Imprenta: 	Pesquisa Agropecuária Brasileira, Brasília, DF, v. 52, n. 8, p. 615-622, fev. 2017.	
Idioma: 	Inglês	
Notas: 	Título em português: Caracterização genética de genes para cor da pelagem do núcleo de conservação da ovelha Crioula no Brasil.	
Conteúdo: 	The objective of this work was to identify single nucleotide polymorphisms (SNPs) in resequencing data from MC1R, ASIP, and TYRP1 genes derived from Crioula sheep (Ovis aris) with different coat colors. Polymorphisms in the ASIP (agouti-signaling protein), MC1R (melanocortin 1 receptor), and TRYP1 (tyrosinase-related protein 1) genes were analyzed in 115 sheep from Embrapa?s conservation nucleus of crioula sheep, in Brazil. A total of 7,914 bp were sequenced per animal, and 14 SNPs were identified. Two additional assays were performed to detect duplications and deletions in the ASIP gene. Ninety-five percent of the coat color variation was explained by epistatic interactions observed between specific alleles in the MC1R and ASIP genes. Evidence suggests an important role of TYRP1 variants for wool color, despite their low frequencies. The marker panel was efficient enough in predicting coat color in the studied animals and, therefore, can be used to implement a marker-assisted selection program in the conservation nucleus of sheep of the crioula breed.	
Palavras-Chave: 	ASIP; Conservação de recurso genético; Genetic resources conservation; MC1R; Ovis aris; Seleção assistida por marcadores; TYRP1.	
Thesaurus Nal: 	Marker-assisted selection.	
Categoria do assunto: 	--	
URL: 	http://ainfo.cnptia.embrapa.br/digital/bitstream/item/163749/1/Genetic-characterization-of-coat-color.pdf	
Registro original: 	Embrapa Unidades Centrais (AI-SEDE)	
Exemplares: 	AI-SEDE - (61702-1) - UPE - AP - PP - 630.72081 - P474 -  - DIS