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Registro Completo |
Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
Data corrente: |
20/02/2014 |
Data da última atualização: |
10/03/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
MACHADO, G. M.; FERREIRA, A. R.; GUARDIEIRO, M. M.; BASTOS, M. R.; CARVALHO, J. O.; LUCCI, C. M.; DIESEL, T. O.; SARTORI, R.; RUMPF, R.; FRANCO, M. M.; DODE, M. A. N. |
Afiliação: |
GRAZIELI M. MACHADO, UNB; ALLICE R. FERREIRA, SÃO PAULO STATE UNIVERSITY; MONIQUE M. GUARDIEIRO, ESALQ; MICHELE R. BASTOS, SÃO PAULO STATE UNIVERSITY; JOSÉ O. CARVALHO, ESALQ; CAROLINA M. LUCCI, UNB; TIAGO O. DIESEL, UNB; ROBERTO SARTORI, ESALQ; RODOLFO RUMPF, CENARGEN; MAURICIO MACHAIM FRANCO, CENARGEN; MARGOT ALVES NUNES DODE, CENARGEN. |
Título: |
Morphology, sex ratio and gene expression of Day 14 in vivo and in vitro bovine embryos. |
Ano de publicação: |
2013 |
Fonte/Imprenta: |
Reproduction, Fertility and Development, v. 25, p. 600-608, 2013. |
Idioma: |
Inglês |
Palavras-Chave: |
Agarose tunnels; Post-hatching embryos. |
Categoria do assunto: |
-- |
Marc: |
LEADER 00756naa a2200253 a 4500 001 1980686 005 2023-03-10 008 2013 bl uuuu u00u1 u #d 100 1 $aMACHADO, G. M. 245 $aMorphology, sex ratio and gene expression of Day 14 in vivo and in vitro bovine embryos.$h[electronic resource] 260 $c2013 653 $aAgarose tunnels 653 $aPost-hatching embryos 700 1 $aFERREIRA, A. R. 700 1 $aGUARDIEIRO, M. M. 700 1 $aBASTOS, M. R. 700 1 $aCARVALHO, J. O. 700 1 $aLUCCI, C. M. 700 1 $aDIESEL, T. O. 700 1 $aSARTORI, R. 700 1 $aRUMPF, R. 700 1 $aFRANCO, M. M. 700 1 $aDODE, M. A. N. 773 $tReproduction, Fertility and Development$gv. 25, p. 600-608, 2013.
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Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
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Registro Completo
Biblioteca(s): |
Embrapa Agricultura Digital; Embrapa Pecuária Sudeste. |
Data corrente: |
29/09/2016 |
Data da última atualização: |
28/03/2019 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
OLIVEIRA, P. P. A.; TIZIOTO, P. C.; MALAGO JUNIOR, W.; NASCIMENTO, M. L. do; CESAR, A. S. M.; DINIZ, W. J. da S.; SOUZA, M. M. de; LANNA, D. P. D.; TULLIO, R. R.; MOURAO, G. B.; MUDADU, M. de A.; COUTINHO, L. L.; REGITANO, L. C. de A. |
Afiliação: |
PATRICIA PERONDI ANCHAO OLIVEIRA, CPPSE; Polyana Cristine Tizioto, UFSCar; WILSON MALAGO JUNIOR, CPPSE; Michele Lopes do Nascimento, USP; Aline Silva Mello Cesar, USP; Wellison Jarles da Silva Diniz, UFSCar; Marcela Maria de Souza, UFSCar; Dante Pazzanese Duarte Lanna, USP; RYMER RAMIZ TULLIO, CPPSE; Gerson Barreto Mourão, USP; MAURICIO DE ALVARENGA MUDADU, CNPTIA; Luiz Lehmann Coutinho, USP; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
Título: |
A single nucleotide polymorphism in NEUROD1 is associated with production traits in nelore beef cattle. |
Ano de publicação: |
2016 |
Fonte/Imprenta: |
Genetics and Molecular Research, v. 15, n. 2, p. 1-8, 2016. |
DOI: |
10.4238/gmr.15028161 |
Idioma: |
Inglês |
Conteúdo: |
Feed efficiency and carcass characteristics are late-measured traits. The detection of molecular markers associated with them can help breeding programs to select animals early in life, and to predict breeding values with high accuracy. The objective of this study was to identify polymorphisms in the functional and positional candidate gene NEUROD1 (neurogenic differentiation 1), and investigate their associations with production traits in reference families of Nelore cattle. A total of 585 steers were used, from 34 sires chosen to represent the variability of this breed. By sequencing 14 animals with extreme residual feed intake (RFI) values, seven single nucleotide polymorphisms (SNPs) in NEUROD1 were identified. The investigation of marker effects on the target traits RFI, backfat thickness (BFT), ribeye area (REA), average body weight (ABW), and metabolic body weight (MBW) was performed with a mixed model using the restricted maximum likelihood method. SNP1062, which changes cytosine for guanine, had no significant association with RFI or REA. However, we found an additive effect on ABW (P ≤ 0.05) and MBW (P ≤ 0.05), with an estimated allele substitution effect of -1.59 and -0.93 kg0.75, respectively. A dominant effect of this SNP for BFT was also found (P ≤ 0.010). Our results are the first that identify NEUROD1 as a candidate that affects BFT, ABW, and MBW. Once confirmed, the inclusion of this SNP in dense panels may improve the accuracy of genomic selection for these traits in Nelore beef cattle as this SNP is not currently represented on SNP chips. MenosFeed efficiency and carcass characteristics are late-measured traits. The detection of molecular markers associated with them can help breeding programs to select animals early in life, and to predict breeding values with high accuracy. The objective of this study was to identify polymorphisms in the functional and positional candidate gene NEUROD1 (neurogenic differentiation 1), and investigate their associations with production traits in reference families of Nelore cattle. A total of 585 steers were used, from 34 sires chosen to represent the variability of this breed. By sequencing 14 animals with extreme residual feed intake (RFI) values, seven single nucleotide polymorphisms (SNPs) in NEUROD1 were identified. The investigation of marker effects on the target traits RFI, backfat thickness (BFT), ribeye area (REA), average body weight (ABW), and metabolic body weight (MBW) was performed with a mixed model using the restricted maximum likelihood method. SNP1062, which changes cytosine for guanine, had no significant association with RFI or REA. However, we found an additive effect on ABW (P ≤ 0.05) and MBW (P ≤ 0.05), with an estimated allele substitution effect of -1.59 and -0.93 kg0.75, respectively. A dominant effect of this SNP for BFT was also found (P ≤ 0.010). Our results are the first that identify NEUROD1 as a candidate that affects BFT, ABW, and MBW. Once confirmed, the inclusion of this SNP in dense panels may improve the accuracy of genomic s... Mostrar Tudo |
Palavras-Chave: |
Candidate gene; Feed efficiency; Nelore. |
Thesagro: |
Bos Indicus; Gado de corte; Gado Nelore. |
Thesaurus NAL: |
Body composition; Feed conversion; Zebu. |
Categoria do assunto: |
G Melhoramento Genético X Pesquisa, Tecnologia e Engenharia |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/147967/1/mudadu-gmr-2016.pdf
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Marc: |
LEADER 02711naa a2200385 a 4500 001 2053741 005 2019-03-28 008 2016 bl uuuu u00u1 u #d 024 7 $a10.4238/gmr.15028161$2DOI 100 1 $aOLIVEIRA, P. P. A. 245 $aA single nucleotide polymorphism in NEUROD1 is associated with production traits in nelore beef cattle.$h[electronic resource] 260 $c2016 520 $aFeed efficiency and carcass characteristics are late-measured traits. The detection of molecular markers associated with them can help breeding programs to select animals early in life, and to predict breeding values with high accuracy. The objective of this study was to identify polymorphisms in the functional and positional candidate gene NEUROD1 (neurogenic differentiation 1), and investigate their associations with production traits in reference families of Nelore cattle. A total of 585 steers were used, from 34 sires chosen to represent the variability of this breed. By sequencing 14 animals with extreme residual feed intake (RFI) values, seven single nucleotide polymorphisms (SNPs) in NEUROD1 were identified. The investigation of marker effects on the target traits RFI, backfat thickness (BFT), ribeye area (REA), average body weight (ABW), and metabolic body weight (MBW) was performed with a mixed model using the restricted maximum likelihood method. SNP1062, which changes cytosine for guanine, had no significant association with RFI or REA. However, we found an additive effect on ABW (P ≤ 0.05) and MBW (P ≤ 0.05), with an estimated allele substitution effect of -1.59 and -0.93 kg0.75, respectively. A dominant effect of this SNP for BFT was also found (P ≤ 0.010). Our results are the first that identify NEUROD1 as a candidate that affects BFT, ABW, and MBW. Once confirmed, the inclusion of this SNP in dense panels may improve the accuracy of genomic selection for these traits in Nelore beef cattle as this SNP is not currently represented on SNP chips. 650 $aBody composition 650 $aFeed conversion 650 $aZebu 650 $aBos Indicus 650 $aGado de corte 650 $aGado Nelore 653 $aCandidate gene 653 $aFeed efficiency 653 $aNelore 700 1 $aTIZIOTO, P. C. 700 1 $aMALAGO JUNIOR, W. 700 1 $aNASCIMENTO, M. L. do 700 1 $aCESAR, A. S. M. 700 1 $aDINIZ, W. J. da S. 700 1 $aSOUZA, M. M. de 700 1 $aLANNA, D. P. D. 700 1 $aTULLIO, R. R. 700 1 $aMOURAO, G. B. 700 1 $aMUDADU, M. de A. 700 1 $aCOUTINHO, L. L. 700 1 $aREGITANO, L. C. de A. 773 $tGenetics and Molecular Research$gv. 15, n. 2, p. 1-8, 2016.
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