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Registro Completo |
Biblioteca(s): |
Embrapa Gado de Leite. |
Data corrente: |
23/03/2009 |
Data da última atualização: |
16/02/2024 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
DRUMOND, B. P.; LEITE, J. A.; FONSECA, F. G.; BONJARDIM, C. A.; FERREIRA, P. C. P.; KROON, E. G. |
Afiliação: |
Betânia Paiva Drumond, UFMG; Juliana Almeida Leite, Embrapa Gado de Leite; Flávio Guimarães da Fonseca, FIOCRUZ; Cláudio Antônio Bonjardim, UFMG; Paulo César Peregrino Ferreira, UFMG; Erna Geessien Kroon, UFMG. |
Título: |
Brazilian vaccinia virus strains are genetically divergent and differ from the lister vaccine strain. |
Ano de publicação: |
2008 |
Fonte/Imprenta: |
Microbes and Infection, Dorchester, v. 10, n. 2, p. 185-197, 2008. |
DOI: |
https://doi.org/10.1016/j.micinf.2007.11.005 |
Idioma: |
Inglês |
Conteúdo: |
Vaccinia virus is responsible for an important zoonotic disease affecting dairy cattle and humans in Brazil, but little is known about the origin, epidemiology and evolution of these Brazilian Vaccinia virus strains. In this work, seven Brazilian Vaccinia virus strains and the Lister-derived Brazilian vaccine strain, named Lister-Butantan, were compared based on the sequences of ten host range and virulence related genes. Comparison of Brazilian Vaccinia virus strains with Lister-Butantan revealed several differences. Phylogenetic analyses confirmed the existence of genetically distinct Brazilian Vaccinia virus groups and has not thus far demonstrated a close relationship between Brazilian strains and Lister-Butantan. In this study, the BeAn58058 and SPAn232 strains were grouped together with the Belo Horizonte and Guarani P1 strains. Additionally, genetic polymorphisms in host range and virulence genes as well as differences in the deduced amino acid sequences were detected among Brazilian Vaccinia virus. This genetic diversity may result in a plethora of different biological properties presented by Brazilian Vaccinia virus, including differences in adaptation to the host as well as pathogenic properties. Furthermore, co-circulation of these divergent strains could increase the possibility of recombination events in nature, leading to the formation of new variants with unpredictable pathogenic potential. |
Palavras-Chave: |
Genetic diversity; Genetic polymorphisms; Poxvirus; Poxvirus infections; Smallpox; Vaccine. |
Thesaurus Nal: |
phylogeny; Vaccinia virus. |
Categoria do assunto: |
-- |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/596375/1/Brazilian-vaccinia-virus-strains-are-genetically-divergent-and-differ.pdf
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Marc: |
LEADER 02305naa a2200289 a 4500 001 1596375 005 2024-02-16 008 2008 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1016/j.micinf.2007.11.005$2DOI 100 1 $aDRUMOND, B. P. 245 $aBrazilian vaccinia virus strains are genetically divergent and differ from the lister vaccine strain.$h[electronic resource] 260 $c2008 520 $aVaccinia virus is responsible for an important zoonotic disease affecting dairy cattle and humans in Brazil, but little is known about the origin, epidemiology and evolution of these Brazilian Vaccinia virus strains. In this work, seven Brazilian Vaccinia virus strains and the Lister-derived Brazilian vaccine strain, named Lister-Butantan, were compared based on the sequences of ten host range and virulence related genes. Comparison of Brazilian Vaccinia virus strains with Lister-Butantan revealed several differences. Phylogenetic analyses confirmed the existence of genetically distinct Brazilian Vaccinia virus groups and has not thus far demonstrated a close relationship between Brazilian strains and Lister-Butantan. In this study, the BeAn58058 and SPAn232 strains were grouped together with the Belo Horizonte and Guarani P1 strains. Additionally, genetic polymorphisms in host range and virulence genes as well as differences in the deduced amino acid sequences were detected among Brazilian Vaccinia virus. This genetic diversity may result in a plethora of different biological properties presented by Brazilian Vaccinia virus, including differences in adaptation to the host as well as pathogenic properties. Furthermore, co-circulation of these divergent strains could increase the possibility of recombination events in nature, leading to the formation of new variants with unpredictable pathogenic potential. 650 $aphylogeny 650 $aVaccinia virus 653 $aGenetic diversity 653 $aGenetic polymorphisms 653 $aPoxvirus 653 $aPoxvirus infections 653 $aSmallpox 653 $aVaccine 700 1 $aLEITE, J. A. 700 1 $aFONSECA, F. G. 700 1 $aBONJARDIM, C. A. 700 1 $aFERREIRA, P. C. P. 700 1 $aKROON, E. G. 773 $tMicrobes and Infection, Dorchester$gv. 10, n. 2, p. 185-197, 2008.
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Embrapa Gado de Leite (CNPGL) |
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Registro Completo
Biblioteca(s): |
Embrapa Soja. |
Data corrente: |
08/01/2004 |
Data da última atualização: |
16/10/2007 |
Autoria: |
DALL'AGNOL, A.; ANTONIO, H. |
Título: |
Avaliação da reação das cultivares brasileiras de soja aos nematóides formadores de galhas Meloidogyne javanica e M. incognita. |
Ano de publicação: |
1984 |
Fonte/Imprenta: |
In: SEMINÁRIO NACIONAL DE PESQUISA DE SOJA, 3., 1984, Campinas. Resumos... Londrina: Embrapa-CNPSo, 1984. |
Páginas: |
p. 26. |
Idioma: |
Português |
Categoria do assunto: |
-- |
Marc: |
LEADER 00497naa a2200133 a 4500 001 1466141 005 2007-10-16 008 1984 bl uuuu u00u1 u #d 100 1 $aDALL'AGNOL, A. 245 $aAvaliação da reação das cultivares brasileiras de soja aos nematóides formadores de galhas Meloidogyne javanica e M. incognita. 260 $c1984 300 $ap. 26. 700 1 $aANTONIO, H. 773 $tIn: SEMINÁRIO NACIONAL DE PESQUISA DE SOJA, 3., 1984, Campinas. Resumos... Londrina: Embrapa-CNPSo, 1984.
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