| |
|
|
| Registros recuperados : 417 | |
| 5. |  | NINOV, K.; ALVES, H. J.; NONES, K.; ROSARIO, M. F.; LEDUR, M. C.; COUTINHO, L. L. Investigação do gene da leptina em aves (Gallus gallus). In: CONFERÊNCIA APINCO DE CIÊNCIA E TECNOLOGIA AVÍCOLAS, 2007, Santos, SP. Anais... Campinas: FACTA, 2007. Trabalhos de pesquisa. p. 166. Projeto n . 01.02.102.10-10.| Biblioteca(s): Embrapa Suínos e Aves. |
|   |
| 9. | | CORTEZ, T.; MONTENEGRO, H.; COUTINHO, L. L.; REGITANO, L. C. de A.; ANDRADE, S. C. S. Molecular evolution and signatures of selective pressures on Bos, focusing on the Nelore breed (Bos indicus). Plos One, v. 17, n. 12, e0279091, 2022. 19 p.| Biblioteca(s): Embrapa Pecuária Sudeste. |
|  |
| 10. | | ZANELLA, E. L.; LEDUR, M. C.; SCHMIDT, G. S.; JAENISCH, F. R. F.; COUTINHO, L. L. Development of a new reference population for QTL detection in poultry. In: ANNUAL MEETING, 89., 2000, Montreal, Canadá. Abstracts... Montreal: PSA, 2000. p. 61| Biblioteca(s): Embrapa Suínos e Aves. |
| |
| 14. | | ZIOBER, I. L.; PAIÃO, F. G.; BINNECK, E.; COUTINHO, L. L.; NEPOMUCENO, A. L.; SHIMOKOMAKI, M. Identificação de diferentes transcritos do gene que codifica proteína receptora de rianodina tipo 1 em frangos submetidos ao teste do halotano. In: SEMANA DE BIOTECNOLOGIA, 4., 208, Londrina. Anais... Londrina: UEL. Departamento de Bioquímica e Biotecnologia, 2008. p. 22.| Biblioteca(s): Embrapa Soja. |
| |
| Registros recuperados : 417 | |
|
|
|
Registro Completo
|
Biblioteca(s): |
Embrapa Pecuária Sudeste. |
|
Data corrente: |
08/03/2023 |
|
Data da última atualização: |
08/03/2023 |
|
Tipo da produção científica: |
Artigo em Periódico Indexado |
|
Circulação/Nível: |
A - 1 |
|
Autoria: |
CORTEZ, T.; MONTENEGRO, H.; COUTINHO, L. L.; REGITANO, L. C. de A.; ANDRADE, S. C. S. |
|
Afiliação: |
THAINÁ CORTEZ, Universidade de São Paulo; HORÁCIO MONTENEGRO, Escola Superior de Agricultura Luiz de Queiroz, Universidade de São Paulo; LUIZ L. COUTINHO, Escola Superior de Agricultura Luiz de Queiroz, Universidade de São Paulo; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE; SÔNIA C. S. ANDRADE, Universidade de São Paulo. |
|
Título: |
Molecular evolution and signatures of selective pressures on Bos, focusing on the Nelore breed (Bos indicus). |
|
Ano de publicação: |
2022 |
|
Fonte/Imprenta: |
Plos One, v. 17, n. 12, e0279091, 2022. |
|
Páginas: |
19 p. |
|
DOI: |
10.1371/journal.pone.0279091 |
|
Idioma: |
Inglês |
|
Conteúdo: |
Evolutionary history leads to genome changes over time, especially for species that have experienced intense selective pressures over a short period. Here, we investigated the genomic evolution of Bos species by searching for potential selection signatures, focusing on Nelore, an economically relevant cattle breed in Brazil. We assessed the genomic processes determining the molecular evolution across Nelore and thirteen other related taxa by evaluating (i) amino acid sequence conservation, (ii) the dN/dS ratio, and (iii) gene families? turnover rate (lambda. Low conserved regions potentially associated with fatty acid metabolism seem to reflect differences in meat fat content in taxa with different evolutionary histories. All Bos species presented genes under positive selection, especially B. indicus and Nelore, which include transport protein cobalamin, glycolipid metabolism, and hormone signaling. These findings could be explained by constant selective pressures to obtain higher immune resistance and efficient metabolism. The gene contraction rate across the Nelore + B. indicus branch was almost nine times higher than that in other lineages (lambda = 0.01043 vs. 0.00121), indicating gene losses during the domestication process. Amino acid biosynthesis, reproductive and innate immune system-related pathways were associated with genes recognized within the most frequent rapidly evolving gene families and in genes under positive selection, supporting the substantial relevance of such traits from a domestication perspective. Our data provide new insights into how the genome may respond to intense artificial selection in distinct taxa, and reinforces the presence of selective pressures on traits potentially relevant for future animal breeding investments. MenosEvolutionary history leads to genome changes over time, especially for species that have experienced intense selective pressures over a short period. Here, we investigated the genomic evolution of Bos species by searching for potential selection signatures, focusing on Nelore, an economically relevant cattle breed in Brazil. We assessed the genomic processes determining the molecular evolution across Nelore and thirteen other related taxa by evaluating (i) amino acid sequence conservation, (ii) the dN/dS ratio, and (iii) gene families? turnover rate (lambda. Low conserved regions potentially associated with fatty acid metabolism seem to reflect differences in meat fat content in taxa with different evolutionary histories. All Bos species presented genes under positive selection, especially B. indicus and Nelore, which include transport protein cobalamin, glycolipid metabolism, and hormone signaling. These findings could be explained by constant selective pressures to obtain higher immune resistance and efficient metabolism. The gene contraction rate across the Nelore + B. indicus branch was almost nine times higher than that in other lineages (lambda = 0.01043 vs. 0.00121), indicating gene losses during the domestication process. Amino acid biosynthesis, reproductive and innate immune system-related pathways were associated with genes recognized within the most frequent rapidly evolving gene families and in genes under positive selection, supporting the substantial relevance... Mostrar Tudo |
|
Palavras-Chave: |
Amino acid biosynthesis; Genomic evolution of Bos species; Intense artificial selection in distinct taxa. |
|
Thesagro: |
Gado Nelore. |
|
Categoria do assunto: |
G Melhoramento Genético |
|
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1152197/1/MolecularEvolutionSignatures.pdf
|
|
Marc: |
LEADER 02560naa a2200241 a 4500
001 2152197
005 2023-03-08
008 2022 bl uuuu u00u1 u #d
024 7 $a10.1371/journal.pone.0279091$2DOI
100 1 $aCORTEZ, T.
245 $aMolecular evolution and signatures of selective pressures on Bos, focusing on the Nelore breed (Bos indicus).$h[electronic resource]
260 $c2022
300 $a19 p.
520 $aEvolutionary history leads to genome changes over time, especially for species that have experienced intense selective pressures over a short period. Here, we investigated the genomic evolution of Bos species by searching for potential selection signatures, focusing on Nelore, an economically relevant cattle breed in Brazil. We assessed the genomic processes determining the molecular evolution across Nelore and thirteen other related taxa by evaluating (i) amino acid sequence conservation, (ii) the dN/dS ratio, and (iii) gene families? turnover rate (lambda. Low conserved regions potentially associated with fatty acid metabolism seem to reflect differences in meat fat content in taxa with different evolutionary histories. All Bos species presented genes under positive selection, especially B. indicus and Nelore, which include transport protein cobalamin, glycolipid metabolism, and hormone signaling. These findings could be explained by constant selective pressures to obtain higher immune resistance and efficient metabolism. The gene contraction rate across the Nelore + B. indicus branch was almost nine times higher than that in other lineages (lambda = 0.01043 vs. 0.00121), indicating gene losses during the domestication process. Amino acid biosynthesis, reproductive and innate immune system-related pathways were associated with genes recognized within the most frequent rapidly evolving gene families and in genes under positive selection, supporting the substantial relevance of such traits from a domestication perspective. Our data provide new insights into how the genome may respond to intense artificial selection in distinct taxa, and reinforces the presence of selective pressures on traits potentially relevant for future animal breeding investments.
650 $aGado Nelore
653 $aAmino acid biosynthesis
653 $aGenomic evolution of Bos species
653 $aIntense artificial selection in distinct taxa
700 1 $aMONTENEGRO, H.
700 1 $aCOUTINHO, L. L.
700 1 $aREGITANO, L. C. de A.
700 1 $aANDRADE, S. C. S.
773 $tPlos One$gv. 17, n. 12, e0279091, 2022.
Download
Esconder MarcMostrar Marc Completo |
|
Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
|
|
Biblioteca |
ID |
Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
Fechar
|
| Nenhum registro encontrado para a expressão de busca informada. |
|
|
