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Registro Completo |
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Biblioteca(s): |
Embrapa Agricultura Digital. |
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Data corrente: |
21/11/2012 |
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Data da última atualização: |
14/04/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
LEPESANT, J. M. J.; COSSEAU, C.; BOISSIER, J.; FREITAG, M.; PORTELA, J.; CLIMENT, D.; PERRIN, C.; ZERLOTINI, A.; GRUNAU, C. |
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Afiliação: |
JULIE M. J. LEPESANT, Université de Perpignan Via Domitia; CÉLINE COSSEAU, Université de Perpignan Via Domitia; JÉROME BOISSIER, Université de Perpignan Via Domitia; MICHAEL FREITAG, Oregon State University; JULIEN PORTELA, Université de Perpignan Via Domitia; DÉBORAH CLIMENT, Université de Perpignan Via Domitia; CÉCILE PERRIN, Université de Perpignan Via Domitia; ADHEMAR ZERLOTINI NETO, CNPTIA; CHRISTOPH GRUNAU, Université de Perpignan Via Domitia. |
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Título: |
Chromatin structural changes around satellite repeats on the female sex chromosome in Schistosoma mansoni and their possible role in sex chromosome emergence. |
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Ano de publicação: |
2012 |
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Fonte/Imprenta: |
Genome Biology, v. 13, 2012. |
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Páginas: |
15 p. |
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DOI: |
10.1186/gb-2012-13-2-r14 |
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Idioma: |
Inglês |
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Conteúdo: |
Background: In the leuphotrochozoan parasitic platyhelminth Schistosoma mansoni, male individuals are homogametic (ZZ) whereas females are heterogametic (ZW). To elucidate the mechanisms that led to the emergence of sex chromosomes, we compared the genomic sequence and the chromatin structure of male and female individuals. As for many eukaryotes, the lower estimate for the repeat content is 40%, with an unknown proportion of domesticated repeats. We used massive sequencing to de novo assemble all repeats, and identify unambiguously Z-specific, W-specific and pseudoautosomal regions of the S. mansoni sex chromosomes. Results: We show that 70 to 90% of S. mansoni W and Z are pseudoautosomal. No female-specific gene could be identified. Instead, the W-specific region is composed almost entirely of 36 satellite repeat families, of which 33 were previously unknown. Transcription and chromatin status of female-specific repeats are stage-specific: for those repeats that are transcribed, transcription is restricted to the larval stages lacking sexual dimorphism. In contrast, in the sexually dimorphic adult stage of the life cycle, no transcription occurs. In addition, the euchromatic character of histone modifications around the W-specific repeats decreases during the life cycle. Recombination repression occurs in this region even if homologous sequences are present on both the Z and W chromosomes. Conclusion: Our study provides for the first time evidence for the hypothesis that, at least in organisms with a ZW type of sex chromosomes, repeat-induced chromatin structure changes could indeed be the initial event in sex chromosome emergence. MenosBackground: In the leuphotrochozoan parasitic platyhelminth Schistosoma mansoni, male individuals are homogametic (ZZ) whereas females are heterogametic (ZW). To elucidate the mechanisms that led to the emergence of sex chromosomes, we compared the genomic sequence and the chromatin structure of male and female individuals. As for many eukaryotes, the lower estimate for the repeat content is 40%, with an unknown proportion of domesticated repeats. We used massive sequencing to de novo assemble all repeats, and identify unambiguously Z-specific, W-specific and pseudoautosomal regions of the S. mansoni sex chromosomes. Results: We show that 70 to 90% of S. mansoni W and Z are pseudoautosomal. No female-specific gene could be identified. Instead, the W-specific region is composed almost entirely of 36 satellite repeat families, of which 33 were previously unknown. Transcription and chromatin status of female-specific repeats are stage-specific: for those repeats that are transcribed, transcription is restricted to the larval stages lacking sexual dimorphism. In contrast, in the sexually dimorphic adult stage of the life cycle, no transcription occurs. In addition, the euchromatic character of histone modifications around the W-specific repeats decreases during the life cycle. Recombination repression occurs in this region even if homologous sequences are present on both the Z and W chromosomes. Conclusion: Our study provides for the first time evidence for the hypothesis that, ... Mostrar Tudo |
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Thesaurus Nal: |
Schistosoma. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/70524/1/gb-2012-13-2-r14.pdf
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Marc: |
LEADER 02420naa a2200253 a 4500
001 1940197
005 2020-04-14
008 2012 bl uuuu u00u1 u #d
024 7 $a10.1186/gb-2012-13-2-r14$2DOI
100 1 $aLEPESANT, J. M. J.
245 $aChromatin structural changes around satellite repeats on the female sex chromosome in Schistosoma mansoni and their possible role in sex chromosome emergence.$h[electronic resource]
260 $c2012
300 $a15 p.
520 $aBackground: In the leuphotrochozoan parasitic platyhelminth Schistosoma mansoni, male individuals are homogametic (ZZ) whereas females are heterogametic (ZW). To elucidate the mechanisms that led to the emergence of sex chromosomes, we compared the genomic sequence and the chromatin structure of male and female individuals. As for many eukaryotes, the lower estimate for the repeat content is 40%, with an unknown proportion of domesticated repeats. We used massive sequencing to de novo assemble all repeats, and identify unambiguously Z-specific, W-specific and pseudoautosomal regions of the S. mansoni sex chromosomes. Results: We show that 70 to 90% of S. mansoni W and Z are pseudoautosomal. No female-specific gene could be identified. Instead, the W-specific region is composed almost entirely of 36 satellite repeat families, of which 33 were previously unknown. Transcription and chromatin status of female-specific repeats are stage-specific: for those repeats that are transcribed, transcription is restricted to the larval stages lacking sexual dimorphism. In contrast, in the sexually dimorphic adult stage of the life cycle, no transcription occurs. In addition, the euchromatic character of histone modifications around the W-specific repeats decreases during the life cycle. Recombination repression occurs in this region even if homologous sequences are present on both the Z and W chromosomes. Conclusion: Our study provides for the first time evidence for the hypothesis that, at least in organisms with a ZW type of sex chromosomes, repeat-induced chromatin structure changes could indeed be the initial event in sex chromosome emergence.
650 $aSchistosoma
700 1 $aCOSSEAU, C.
700 1 $aBOISSIER, J.
700 1 $aFREITAG, M.
700 1 $aPORTELA, J.
700 1 $aCLIMENT, D.
700 1 $aPERRIN, C.
700 1 $aZERLOTINI, A.
700 1 $aGRUNAU, C.
773 $tGenome Biology$gv. 13, 2012.
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Registro original: |
Embrapa Agricultura Digital (CNPTIA) |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Solos. Para informações adicionais entre em contato com cnps.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Solos. |
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Data corrente: |
16/04/2010 |
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Data da última atualização: |
16/04/2010 |
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Tipo da produção científica: |
Artigo de Divulgação na Mídia |
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Autoria: |
BENITES, V. de M.; TANNUS, V. R.; MENEZES, J. F. S.; SIMON, G. A.; COSTA, K. A. de P.; MARTINS, E. de S. |
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Afiliação: |
VINICIUS DE MELO BENITES, CNPS; VICTOR RODRIGUES TANNUS, FESURV; JUNE FARIA SCHERRER MENEZES, FESURV; GUSTAVO ANDRÉ SIMON, FESURV; KATIA APARECIDA DE P. COSTA, FESURV; EDER DE SOUZA MARTINS, CPAC. |
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Título: |
Avaliação da capacidade de extração de nutrientes por plantas de cobertura, adubadas com pó de rocha obtido a partir da brecha alcalina de Santo Antônio da Barra-GO. |
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Ano de publicação: |
2009 |
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Fonte/Imprenta: |
Centro Tecnológico COMIGO Resultados 2009, Goiânia, p. 56-57, 2009. |
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Idioma: |
Português |
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Thesagro: |
Adubação; Fertilizante. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 00669naa a2200193 a 4500
001 1696784
005 2010-04-16
008 2009 bl --- 0-- u #d
100 1 $aBENITES, V. de M.
245 $aAvaliação da capacidade de extração de nutrientes por plantas de cobertura, adubadas com pó de rocha obtido a partir da brecha alcalina de Santo Antônio da Barra-GO.
260 $c2009
650 $aAdubação
650 $aFertilizante
700 1 $aTANNUS, V. R.
700 1 $aMENEZES, J. F. S.
700 1 $aSIMON, G. A.
700 1 $aCOSTA, K. A. de P.
700 1 $aMARTINS, E. de S.
773 $tCentro Tecnológico COMIGO Resultados 2009, Goiânia, p. 56-57, 2009.
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