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| Registros recuperados : 206 | |
| 103. |  | COSTA, F. A. da; BARBIERI, R. L.; ESLABÃO, M.; HEIDEN, G.; SOSINSKI JUNIOR, E. E.; MARCHI, M. M. Mapeamento e análise geográfica da conservação in situ de butiazais no bioma pampa. In: CONGRESSO BRASILEIRO DE RECURSOS GENÉTICOS, 5., 2018, Fortaleza. Anais... Fortaleza: Sociedade Brasileira de Recursos Genéticos, 2018.| Biblioteca(s): Embrapa Clima Temperado. |
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| 107. | | DALLA COSTA, F. A.; TAVERNARI, F. de C.; DALLA COSTA, O. A.; CASTRO, F. F. de; REMUS, A. Enriquecimento com ácidos graxos da série ômega 3 em carne de aves e ovos. Pubvet, Londrina, v. 11, n. 2, p. 113-123, 2017.| Biblioteca(s): Embrapa Suínos e Aves. |
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| 109. | | GOULART, D. F.; ALMEIDA, R. P. de; RESENDE, K. C.; COSTA, F. A. M. da; BEZERRA, J. R. C. O desafio da estruturação da cadeia produtiva do amendoim no semiárido do Nordeste. Organizações Rurais & Agroindustriais, Lavras, v. 19, n. 1, p. 47-59, 2017.| Biblioteca(s): Embrapa Algodão. |
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| 111. | | CARBONARI, T.; SOSINSKI JUNIOR, E. E.; BARBIERI, R. L.; COSTA, F. A. da; HAGEMANN, A.; DUTRA, F. A. Conservação in situ de butia odorata: distribuição Espacial de indivíduos na paisagem. In: SIMPÓSIO DE RECURSOS GENÉTICOS PARA A AMÉRICA LATINA E CARIBE, 10., 2015, Bento Gonçalves. Recursos genéticos no século 21: de Vavilov a Svalbard. Anais... [s.l.]: Sociedade Brasileira de Recursos Genéticos, 2015.| Biblioteca(s): Embrapa Clima Temperado. |
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| 113. | | NEITZKE, R. S.; BARBIERI, R. L.; COSTA, F. A. da; VASCONCELOS, C. S. de; ROMANO, C. M.; HEIDEN, G. Conservação ex situ de variedades locais de Cucurbita do Rio Grande do Sul. In: CONGRESSO BRASILEIRO DE MELHORAMENTOS DE PLANTAS, 5., 2009, Guarapari. O melhoramento e os novos cenários da agricultura: anais. Vitória: Incaper, 2009. 1 CD-ROM.| Biblioteca(s): Embrapa Clima Temperado. |
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| 117. | | BRITO, D. P. P. de S.; CASTRO, A. F. de; MENDES, W.; JACCOUD, A.; RAMOS, D. P.; COSTA, F. A. Estudo das reacoes a micronutrientes em latossolos vermelho-escuro sob vegetacao de cerrado. Pesquisa Agropecuaria Brasileira, Serie Agronomia, v.6, p.17-22, 1971.| Biblioteca(s): Embrapa Cerrados. |
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| 118. | | BRITO, D. P. P. de S.; CASTRO, A. F. de; MENDES, W.; JACCOUD, A.; RAMOS, D. P.; COSTA, F. A. Estudo das reações a micronutrientes em latossolo vermelho-escuro sob vegetação de cerrado. Pesquisa Agropecuária Brasileira, Rio de Janeiro, v. 6, p. 17-22, 1971. (Agronomia, 4). Título em inglês: A Plant nutrient study on a dark red latosol under Cerrado vegetation.
A partir do v. 3 (1968) é constituída de duas partes: Série Agronomia e Série Veterinária, publicadas também separadamente.| Biblioteca(s): Embrapa Unidades Centrais. |
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| Registros recuperados : 206 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
15/02/2016 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
CAMPOS, A. P.; MIRANDA, D. F. H.; ALVES, G. B. B.; CARNEIRO, M. S.; PRIANTI, M. G.; GONÇALVES, L. M. F.; CASTRO, V.; COSTA, F. A. L. |
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Afiliação: |
ÂNGELA P. CAMPOS, UFPI; DAYANE F. H. MIRANDA, UFPI; GEÓRGIA B. B. ALVES, UFPI; MICHERLENE S. CARNEIRO, UFPI; MARIA G. PRIANTI, UFPI; LARISSA M. F. GONÇALVES, UFPI; VANESSA CASTRO, Instituo Biológico de São Paulo; FRANCISCO A. L. COSTA, UFPI. |
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Título: |
The role of alveolar type II cells in swine leptospirosis. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 35, n. 7, p. 620-626. jul. 2015. |
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Idioma: |
Inglês |
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Notas: |
Título em português: O papel das células alveolares tipo II na leptospirose suína. |
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Conteúdo: |
This study aimed to investigate a possible relationship between alveolar type II cells and the inflammatory response to infection with Leptospira spp., and thus comprise a further element that can be involved in the pathogenesis of lung injury in naturally infected pigs. The study group consisted of 73 adult pigs that were extensively reared and slaughtered in Teresina, Piauí state, and Timon, Maranhão state, Brazil. The diagnosis of leptospirosis was made using the microscopic agglutination test (MAT) aided by immunohistochemistry and polymerase chain reaction. The MAT registered the occurrence of anti-Leptospira antibodies in 10.96% (8/73) of the pigs. Immunohistochemistry allowed for the visualization of the Leptospira spp. antigen in the lungs of 87.67% (64/73) of the pigs. There was hyperplasia of bronchus-associated lymphoid tissue and circulatory changes, such as congestion of alveolar septa, parenchymal hemorrhage and edema within the alveoli. Lung inflammation was more intense (p = 0.0312) in infected animals, which also showed increased thickening of the alveolar septa (p = 0.0006). Evaluation of alveolar type II (ATII) cells using an anti-TTF-1 (Thyroid Transcription Factor-1) antibody showed that there were more immunostained cells in the non-infected pigs (53.8%) than in the infected animals (46.2%) and that there was an inverse correlation between TTF-1 positive cells and the inflammatory infiltrate. There was no amplification of Leptospira DNA in the lung samples, but leptospiral DNA amplification was observed in the kidneys. The results of this study showed that a relationship exists between a decrease in alveolar type II cells and a leptospire infection. Thus, this work points to the importance of studying the ATII cells as a potential marker of the level of lung innate immune response during leptospirosis in pigs. MenosThis study aimed to investigate a possible relationship between alveolar type II cells and the inflammatory response to infection with Leptospira spp., and thus comprise a further element that can be involved in the pathogenesis of lung injury in naturally infected pigs. The study group consisted of 73 adult pigs that were extensively reared and slaughtered in Teresina, Piauí state, and Timon, Maranhão state, Brazil. The diagnosis of leptospirosis was made using the microscopic agglutination test (MAT) aided by immunohistochemistry and polymerase chain reaction. The MAT registered the occurrence of anti-Leptospira antibodies in 10.96% (8/73) of the pigs. Immunohistochemistry allowed for the visualization of the Leptospira spp. antigen in the lungs of 87.67% (64/73) of the pigs. There was hyperplasia of bronchus-associated lymphoid tissue and circulatory changes, such as congestion of alveolar septa, parenchymal hemorrhage and edema within the alveoli. Lung inflammation was more intense (p = 0.0312) in infected animals, which also showed increased thickening of the alveolar septa (p = 0.0006). Evaluation of alveolar type II (ATII) cells using an anti-TTF-1 (Thyroid Transcription Factor-1) antibody showed that there were more immunostained cells in the non-infected pigs (53.8%) than in the infected animals (46.2%) and that there was an inverse correlation between TTF-1 positive cells and the inflammatory infiltrate. There was no amplification of Leptospira DNA in the lung samp... Mostrar Tudo |
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Thesaurus NAL: |
Immunohistochemistry; Lungs; Swine. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/138963/1/The-role-of-alveolar-type.pdf
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Marc: |
LEADER 02641naa a2200253 a 4500
001 2036902
005 2017-12-29
008 2015 bl uuuu u00u1 u #d
100 1 $aCAMPOS, A. P.
245 $aThe role of alveolar type II cells in swine leptospirosis.
260 $c2015
500 $aTítulo em português: O papel das células alveolares tipo II na leptospirose suína.
520 $aThis study aimed to investigate a possible relationship between alveolar type II cells and the inflammatory response to infection with Leptospira spp., and thus comprise a further element that can be involved in the pathogenesis of lung injury in naturally infected pigs. The study group consisted of 73 adult pigs that were extensively reared and slaughtered in Teresina, Piauí state, and Timon, Maranhão state, Brazil. The diagnosis of leptospirosis was made using the microscopic agglutination test (MAT) aided by immunohistochemistry and polymerase chain reaction. The MAT registered the occurrence of anti-Leptospira antibodies in 10.96% (8/73) of the pigs. Immunohistochemistry allowed for the visualization of the Leptospira spp. antigen in the lungs of 87.67% (64/73) of the pigs. There was hyperplasia of bronchus-associated lymphoid tissue and circulatory changes, such as congestion of alveolar septa, parenchymal hemorrhage and edema within the alveoli. Lung inflammation was more intense (p = 0.0312) in infected animals, which also showed increased thickening of the alveolar septa (p = 0.0006). Evaluation of alveolar type II (ATII) cells using an anti-TTF-1 (Thyroid Transcription Factor-1) antibody showed that there were more immunostained cells in the non-infected pigs (53.8%) than in the infected animals (46.2%) and that there was an inverse correlation between TTF-1 positive cells and the inflammatory infiltrate. There was no amplification of Leptospira DNA in the lung samples, but leptospiral DNA amplification was observed in the kidneys. The results of this study showed that a relationship exists between a decrease in alveolar type II cells and a leptospire infection. Thus, this work points to the importance of studying the ATII cells as a potential marker of the level of lung innate immune response during leptospirosis in pigs.
650 $aImmunohistochemistry
650 $aLungs
650 $aSwine
700 1 $aMIRANDA, D. F. H.
700 1 $aALVES, G. B. B.
700 1 $aCARNEIRO, M. S.
700 1 $aPRIANTI, M. G.
700 1 $aGONÇALVES, L. M. F.
700 1 $aCASTRO, V.
700 1 $aCOSTA, F. A. L.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 35, n. 7, p. 620-626. jul. 2015.
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