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Registro Completo |
Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
Data corrente: |
14/06/2022 |
Data da última atualização: |
28/09/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
MENDES, R. A. G.; BASSO, M. F.; AMORA, D. X.; SILVA, A. P.; PAES-DE-MELO, B.; TOGAWA, R. C.; FREIRE, E. V. S. A.; LISEI-DE-SA, M. E.; MACEDO, L. L. P. de; LOURENCO, I. T.; SA, M. F. G. de. |
Afiliação: |
RENEIDA APARECIDA GODINHO MENDES, UNB; MARCOS FERNANDO BASSO, National Institute of Science and Technology-INCT PlantStress Biotech-EMBRAPA; DEISY XAVIER AMORA; ARINALDO PEREIRA SILVA; BRUNO PAES-DE-MELO, UFV; ROBERTO COITI TOGAWA, Cenargen; ERIKA VALERIA SALIBA ALBUQUERQUE FR, Cenargen; MARIA EUGÊNIA LISEI-DE-SA, EPAMIG; LEONARDO LIMA PEPINO DE MACEDO, Cenargen; ISABELA TRISTAN LOURENCO TESSUTTI, Cenargen; MARIA FATIMA GROSSI DE SA, Cenargen. |
Título: |
In planta RNAi approach targeting three M. incognita effector genes disturbed the process of infection and reduced plant susceptibility. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
Experimental Parasitology, v. 238, 2022, 108246. |
DOI: |
https://doi.org/10.1016/j.exppara.2022.108246 |
Idioma: |
Inglês |
Notas: |
Na publicação: Erika Valéria Saliba Albuquerque; Leonardo Lima Pepino Macedo; Isabela Tristan Lourenço-Tessutti; Maria Fatima Grossi-de-Sa. |
Palavras-Chave: |
Effector proteins; Nematode management; Plant-parasitic nematodes. |
Thesaurus Nal: |
RNA interference. |
Categoria do assunto: |
-- |
Marc: |
LEADER 01110naa a2200301 a 4500 001 2144044 005 2023-09-28 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1016/j.exppara.2022.108246$2DOI 100 1 $aMENDES, R. A. G. 245 $aIn planta RNAi approach targeting three M. incognita effector genes disturbed the process of infection and reduced plant susceptibility.$h[electronic resource] 260 $c2022 500 $aNa publicação: Erika Valéria Saliba Albuquerque; Leonardo Lima Pepino Macedo; Isabela Tristan Lourenço-Tessutti; Maria Fatima Grossi-de-Sa. 650 $aRNA interference 653 $aEffector proteins 653 $aNematode management 653 $aPlant-parasitic nematodes 700 1 $aBASSO, M. F. 700 1 $aAMORA, D. X. 700 1 $aSILVA, A. P. 700 1 $aPAES-DE-MELO, B. 700 1 $aTOGAWA, R. C. 700 1 $aFREIRE, E. V. S. A. 700 1 $aLISEI-DE-SA, M. E. 700 1 $aMACEDO, L. L. P. de 700 1 $aLOURENCO, I. T. 700 1 $aSA, M. F. G. de 773 $tExperimental Parasitology$gv. 238, 2022, 108246.
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Embrapa Recursos Genéticos e Biotecnologia (CENARGEN) |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Amazônia Oriental. Para informações adicionais entre em contato com cpatu.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Amazônia Oriental. |
Data corrente: |
08/09/2017 |
Data da última atualização: |
20/05/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
DUARTE JUNIOR, A. P.; TAVARES, E. J. M.; ALVES, T. V. G.; MOURA, M. R. de; COSTA, C. E. F. da; SILVA JÚNIOR, J. O. C.; COSTA, R. M. R. |
Afiliação: |
Anivaldo Pereira Duarte Junior, UFPA; ERALDO JOSE MADUREIRA TAVARES, CPATU; Taís Vanessa Gabbay Alves, UFPA; Márcia Regina de Moura, UNESP; Carlos Emmerson Ferreira da Costa, UFPA; José Otávio Carréra Silva Júnior, UFPA; Roseane Maria Ribeiro Costa, UFPA. |
Título: |
Chitosan nanoparticles as a modified diclofenac drug release system. |
Ano de publicação: |
2017 |
Fonte/Imprenta: |
Journal of Nanoparticle Research, v. 19, n. 8, article 274, 2017. |
DOI: |
10.1007/s11051-017-3968-6 |
Idioma: |
Inglês |
Conteúdo: |
This study evaluated a modified nanostructured release system employing diclofenac as a drug model. Biodegradable chitosan nanoparticles were prepared with chitosan concentrations between 0.5 and 0.8% ( w/ v) by template polymerization method using methacrylic acid in aqueous solution. Chitosan-poly(methacrylic acid) (CS-PMAA) nanoparticles showed uniform size around 50?100 nm, homogeneous morphology, and spherical shape. Raw material and chitosan nanoparticles were characterized by thermal analysis, Fourier transform infrared spectroscopy (FT-IR), and transmission electron microscopy (TEM), confirming the interaction between chitosan and methacrylic acid during nanoparticles preparation. Diclofenac sorption on the chitosan nanoparticles surface was achieved by incubation in water/ethanol (1:1) drug solution in concentrations of 0.5 and 0.8 mg/mL. The diclofenac amount sorbed per gram of CS-PMAA nanoparticles, when in a 0.5 mg/mL sodium diclofenac solution, was as follows: 12.93, 15, 20.87, and 29.63 mg/g for CS-PMAA nanoparticles 0.5, 0.6, 0.7, and 0.8% ( w/ v), respectively. When a 0.8 mg/mL sodium diclofenac solution was used, higher sorption efficiencies were obtained: For CS-PMAA nanoparticles with chitosan concentrations of 0.5, 0.6, 0.7, and 0.8% ( w/ v), the sorption efficiencies were 33.39, 49.58, 55.23, and 67.2 mg/g, respectively. Diclofenac sorption kinetics followed a second-order kinetics. Drug release from nanoparticles occurred in a period of up to 48 h and obeyed Korsmeyer-Peppas model, which was characterized mainly by Fickian diffusion transport. MenosThis study evaluated a modified nanostructured release system employing diclofenac as a drug model. Biodegradable chitosan nanoparticles were prepared with chitosan concentrations between 0.5 and 0.8% ( w/ v) by template polymerization method using methacrylic acid in aqueous solution. Chitosan-poly(methacrylic acid) (CS-PMAA) nanoparticles showed uniform size around 50?100 nm, homogeneous morphology, and spherical shape. Raw material and chitosan nanoparticles were characterized by thermal analysis, Fourier transform infrared spectroscopy (FT-IR), and transmission electron microscopy (TEM), confirming the interaction between chitosan and methacrylic acid during nanoparticles preparation. Diclofenac sorption on the chitosan nanoparticles surface was achieved by incubation in water/ethanol (1:1) drug solution in concentrations of 0.5 and 0.8 mg/mL. The diclofenac amount sorbed per gram of CS-PMAA nanoparticles, when in a 0.5 mg/mL sodium diclofenac solution, was as follows: 12.93, 15, 20.87, and 29.63 mg/g for CS-PMAA nanoparticles 0.5, 0.6, 0.7, and 0.8% ( w/ v), respectively. When a 0.8 mg/mL sodium diclofenac solution was used, higher sorption efficiencies were obtained: For CS-PMAA nanoparticles with chitosan concentrations of 0.5, 0.6, 0.7, and 0.8% ( w/ v), the sorption efficiencies were 33.39, 49.58, 55.23, and 67.2 mg/g, respectively. Diclofenac sorption kinetics followed a second-order kinetics. Drug release from nanoparticles occurred in a period of up to 48 h and o... Mostrar Tudo |
Palavras-Chave: |
Biopolímero; Nanopartícula; Nanotecnologia; Quitosana. |
Categoria do assunto: |
X Pesquisa, Tecnologia e Engenharia |
Marc: |
LEADER 02347naa a2200253 a 4500 001 2075279 005 2022-05-20 008 2017 bl uuuu u00u1 u #d 024 7 $a10.1007/s11051-017-3968-6$2DOI 100 1 $aDUARTE JUNIOR, A. P. 245 $aChitosan nanoparticles as a modified diclofenac drug release system.$h[electronic resource] 260 $c2017 520 $aThis study evaluated a modified nanostructured release system employing diclofenac as a drug model. Biodegradable chitosan nanoparticles were prepared with chitosan concentrations between 0.5 and 0.8% ( w/ v) by template polymerization method using methacrylic acid in aqueous solution. Chitosan-poly(methacrylic acid) (CS-PMAA) nanoparticles showed uniform size around 50?100 nm, homogeneous morphology, and spherical shape. Raw material and chitosan nanoparticles were characterized by thermal analysis, Fourier transform infrared spectroscopy (FT-IR), and transmission electron microscopy (TEM), confirming the interaction between chitosan and methacrylic acid during nanoparticles preparation. Diclofenac sorption on the chitosan nanoparticles surface was achieved by incubation in water/ethanol (1:1) drug solution in concentrations of 0.5 and 0.8 mg/mL. The diclofenac amount sorbed per gram of CS-PMAA nanoparticles, when in a 0.5 mg/mL sodium diclofenac solution, was as follows: 12.93, 15, 20.87, and 29.63 mg/g for CS-PMAA nanoparticles 0.5, 0.6, 0.7, and 0.8% ( w/ v), respectively. When a 0.8 mg/mL sodium diclofenac solution was used, higher sorption efficiencies were obtained: For CS-PMAA nanoparticles with chitosan concentrations of 0.5, 0.6, 0.7, and 0.8% ( w/ v), the sorption efficiencies were 33.39, 49.58, 55.23, and 67.2 mg/g, respectively. Diclofenac sorption kinetics followed a second-order kinetics. Drug release from nanoparticles occurred in a period of up to 48 h and obeyed Korsmeyer-Peppas model, which was characterized mainly by Fickian diffusion transport. 653 $aBiopolímero 653 $aNanopartícula 653 $aNanotecnologia 653 $aQuitosana 700 1 $aTAVARES, E. J. M. 700 1 $aALVES, T. V. G. 700 1 $aMOURA, M. R. de 700 1 $aCOSTA, C. E. F. da 700 1 $aSILVA JÚNIOR, J. O. C. 700 1 $aCOSTA, R. M. R. 773 $tJournal of Nanoparticle Research$gv. 19, n. 8, article 274, 2017.
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