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1. | | MONTEIRO, M. L. G.; MÁRSICO, E. T.; ROSENTHAL, A.; CONTE-JUNIOR, C. A. Synergistic effect of ultraviolet radiation and high hydrostatic pressure on texture, color, andoxidative stability of refrigerated tilapia fillets. Journal of the Science of Food and Agriculture, v. 99, n. 9, p. 4474-4481, 2019. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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2. | | DELGADO, K.; VIEIRA, C.; DAMMAK, I.; FRASÃO, B.; BRIGIDA, A. I. S.; COSTA, M.; CONTE-JUNIOR, C. Different ultrasound exposure times influence the physicochemical and microbial quality properties in probiotic goat milk yogurt. Molecules, v. 25, 4638, p. 1-22, 2020 Biblioteca(s): Embrapa Agroindústria de Alimentos; Embrapa Agroindústria Tropical. |
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4. | | DELGADO, K. F.; PEREIRA, M. P.; FRASÃO, B.; VIEIRA, C. P.; BRIGIDA, A. I. S.; CONTE JUNIOR, C. Physicochemical and microbiological effects of different sonication times on goat's milk yogurt. In: SIMPÓSIO LATINO AMERICANO DE CIÊNCIA DE ALIMENTOS , 12., 2017, Campinas. Ciência de Alimentos e seu Impacto no Mundo em Transformação. Campinas: UNICAMP, 2017. SLACA, 12. De 4 a 7 de Novembro de 2017. Ref. 71861. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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5. | | FRASÃO, B.; COSTA, M.; SILVA, F.; RODRIGUES, B.; BALTAR, J.; ARAUJO, J.; MOREIRA, D.; TORREZAN, R.; CONTE-JUNIOR, C. Effect of pequi (Caryocar brasiliense) and juçara (Euterpe edulis) waste extract on oxidation process stability in broiler meat treated by UV-C. PLOS ONE, 20 dec., 2018. 17 p. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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7. | | ROSA, L. O. L.; MUZZI, L.; CONTE JUNIOR, C.; BRIGIDA, A. I. S.; SILVA, C. M.; CABRAL, L. M. C. The use of emerging technologies on assisting whey Beta-lactoglobulin hydrolysis aiming low-allergenic ingredients. In: SIMPÓSIO LATINO AMERICANO DE CIÊNCIA DE ALIMENTOS , 12., 2017, Campinas. Ciência de Alimentos e seu Impacto no Mundo em Transformação. Campinas: UNICAMP, 2017. SLACA, 12. De 4 a 7 de Novembro de 2017. Ref. 71322. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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8. | | MONTEIRO, M. L. G.; DELIZA, R.; MARSICO, Eliane T.; ALCANTARA, M. de; CASTRO, I. P. L.; CONTE-JUNIOR, C. A. What Do Consumers Think About Foods Processed by Ultraviolet Radiation and Ultrasound? Foods, v. 11, n. 3, 434, 2022. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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9. | | VIANA, F. M.; DELIZA, R.; MONTEIRO, M. L. G.; MARTINS, I. B. A.; OLIVEIRA, D. C. R.; CONTE-JUNIOR, C. A. Applying free word association to understand the perception of fish as a meal by Brazilians with different consumption frequencies. Journal of Sensory Studies, v. 36, n. 2, e12628, p. 1-9, 2021. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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10. | | PORTO-FORESTI, F.; LOBO, C. M. de O.; PRADO, F. D. do; TORREZAN, R.; FURTADO, A. A. L. de; CONTE JUNIOR, C. A.; MÁRSICO, E. T. Molecular identification of pseudoplatystoma sp. fish fillets by multiplex PCR. Vigilância Sanitária em Debate: sociedade, ciência e tecnologia, v. 2, n. 3, p. 64-70, 2014. título em português: Identificação molecular de filés de peixe pseudoplatystoma sp. por PCR multiplex. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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11. | | GUEDES-OLIVEIRA, J. M.; COSTA-LIMA, B. R. C.; OLIVEIRA, D.; NETO, A.; DELIZA, R.; CONTE-JUNIOR, C. A.; GUIMARÃES, C. F. M. Mixture design approach for the development of reduced fat lamb patties with carboxymethyl cellulose and inulin. Food Science & Nutrition, n. 7, p. 1328-1336, 2019. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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12. | | MONTEIRO, M. L. G.; MÁRSICO, E. T.; DELIZA, R.; CASTRO, V. S.; MUTZ, Y. S.; SOARES JUNIOR, M. S.; CALIARI, M.; SANTOS, E. A.; CONTE-JUNIOR, C. A. Physicochemical and sensory characteristics of pasta enriched with fish (Oreochromis niloticus) waste flour. LWT - Food Science and Technology, v. 111 p. 751-758, 2019. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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13. | | SILVEIRA, M. F. da; COMETTANT RABANAL, R.; VIEIRA, C. P.; CONTE-JUNIOR, C. A.; SOARES, A. G.; FREITAS-SILVA, O.; CABRAL, L. M. C. Carboxymethyl cellulose and sodium alginate edible coating to preserve the physicochemical and microbial quality of strawberry (fragaria ananassa) In: ULHÕA, J. L. R. (Org.). Ciências Biológicas e da terra: princípios fundamentais. Piracanjuba: Editora Conhecimento Livre, 2020, cap. 17. p. 178-193 Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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14. | | MONTEIRO, M. L. G.; MÁRSICO, E. T.; MANO, S. B.; ALVARES, T. DA S.; ROSENTHAL, A.; LEMOS, M.; FERRARI, E.; LÁZARO, C. A.; CONTE-JUNIOR, C. A. Combined effect of high hydrostatic pressure and ultraviolet radiation on quality parameters of refrigerated vacuum-packed tilapia (Oreochromis niloticus) fillets. Scientific Reports, v. 8, 2018. 11 p. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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15. | | MONTEIRO, M. L. G.; MÁRSICO, E. T.; SOARES JUNIOR, M. S.; DELIZA, R.; OLIVEIRA, D. C. R. DE; CONTE-JUNIOR, C. A. Tilapia-waste flour as a natural nutritional replacer for bread: A consumer perspective. Plos One, May, v. 13, n. 5, e0196665, 2018. 8 p. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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16. | | LOBO, C. M. de O.; TORREZAN, R.; FURTADO, A. A. L.; ANTONIASSI, R.; FREITAS, D. de G. C.; FREITAS, S. C. de; PENTEADO, A. L.; OLIVEIRA, C. S. de; CONTE JUNIOR, C. A.; MÁRSICO, E. T. Development and nutritional and sensory evaluation of cachapinta (Pseudoplatystoma sp) pâté. Food Science & Nutrition, v. 3, n. 1, p. 10-16, 2014. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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17. | | FRASÃO, B. DA S.; ROSARIO, A. I. L. DOS S.; RODRIGUES, B. L.; BITTI, H. A.; BALTAR, J. D.; NOGUEIRA, R. I.; COSTA, M. P. DA; CONTE-JUNIOR, C. A. Impact of Juçara (Euterpe edulis) fruit waste extracts on the quality of conventional and antibiotic-free boiler meat. Poultry Science, v. 100, n. 8, August 2021, 101232. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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18. | | CANTO, A. C. V. S.; COSTA-LIMA, B. R. C.; SUMAN, S. P.; MONTEIRO, M. L. G.; MARSICO, E. T.; CONTE-JUNIOR, C. A.; FRANCO, R. M.; SALIM, A. P. A. A.; TORREZAN, R.; SILVA, T. J. P. Fatty acid profile and bacteriological quality of caiman meat subjected to high hydrostatic pressure. LWT - Food Science and Technology, v. 63, p. 872-877, 2015. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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19. | | VIANA, F. M.; MONTEIRO, M. L. G.; FERRARI, R. G.; MUTZ, Y. S.; MARTINS, I. B. A.; SALIM, A. P. A. A.; ALCANTARA, M.; DELIZA, R.; MANO, S. B.; CONTE-JUNIOR, C. A. Multivariate Nature of Fish Freshness Evaluation by Consumers. Foods, v. 11, n. 2144, p. 1-15, 2022. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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20. | | CALDAS, T. W.; MAZZA, K. E. L.; TELES, A. S. C.; MATTOS, G. N.; BRIGIDA, A. I. S.; CONTE-JUNIOR, C. A.; BORGUINI, R. G.; GODOY, R. L. de O.; CABRAL, L. M. C.; TONON, R. V. Phenolic compounds recovery from grape skin using conventional and non-conventional extraction methods. Industrial Crops & Products, v. 111, p. 86-91, 2018. Biblioteca(s): Embrapa Agroindústria de Alimentos. |
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Registros recuperados : 24 | |
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Registro Completo
Biblioteca(s): |
Embrapa Agroindústria de Alimentos. |
Data corrente: |
29/12/2020 |
Data da última atualização: |
04/03/2021 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
MONTENEGRO, J.; SANTOS, L. S. dos; SOUZA, R. G. G. de; LIMA, L. G. B.; MATTOS, D. S.; VIANA, B. P. P. B.; BASTOS, A. C. S. da F.; MUZZI, L.; CONTE-JÚNIOR, C. A.; GIMBA, E. R. P.; FREITAS-SILVA, O. |
Afiliação: |
Júlia Montenegro, Universidade Federal do Estado do Rio de Janeiro, UNIRIO; Lauriza Silva dos Santos, Universidade Federal do Estado do Rio de Janeiro, UNIRIO; Rodrigo Gonçalves Gusmão de Souza, UNIRIO; Larissa Gabrielly Barbosa Lima, Universidade Federal do Estado do Rio de Janeiro, UNIRIO; Daniella Santos Mattos, Instituto Nacional do Câncer, INCa; Bruna Prunes Pena Baroni Viana, Instituto Nacional do Câncer, INCa; Ana Clara Santos da Fonseca Bastos, Instituto Nacional do Câncer, INCa; Leda Muzzi, Universidade Federal Fluminense, UFF; Carlos Adam Conte-Júnior, Universidade Federal Fluminense, UFF; Etel Rodrigues Pereira Gimba, Instituto Nacional do Câncer, INCa; Universidade Federal Fluminense, UFF; OTNIEL FREITAS SILVA, CTAA. |
Título: |
Bioactive compounds, antioxidant activity and antiproliferative effects in prostate cancer cells of green and roasted coffee extracts obtained by microwave-assisted extraction (MAE). |
Ano de publicação: |
2021 |
Fonte/Imprenta: |
Food Research International, v. 140, 110014, 2021. |
DOI: |
https://doi.org/10.1016/j.foodres.2020.110014 |
Idioma: |
Inglês |
Notas: |
Epub 2020 Dec 15. |
Conteúdo: |
Coffee consumption has been investigated as a protective factor against prostate cancer. Coffee may be related to prostate cancer risk reduction due to its phytochemical compounds, such as caffeine, chlorogenic acids, and trigonelline. The roasting process affects the content of the phytochemicals and undesired compounds can be formed. Microwave-assisted extraction is an alternative to conventional extraction techniques since it preserves more bioactive compounds. Therefore, this study aimed to evaluate the phytochemical composition and the putative preventive effects in prostate cancer development of coffee beans submitted to four different coffee- roasting degrees extracted using microwave-assisted extraction. Coffea arabica green beans (1) were roasted into light (2), medium (3) and dark (4) and these four coffee samples were submitted to microwave-assisted extraction. The antioxidant capacity of these samples was evaluated by five different methods. Caffeine, chlorogenic acid and caffeic acid were measured through HPLC. Samples were tested against PC-3 and DU-145 metastatic prostate cancer cell lines regarding their effects on cell viability, cell cycle progression and apoptotic cell death. We found that green and light roasted coffee extracts had the highest antioxidant activity. Caffeine content was not affected by roasting, chlorogenic acid was degraded due to the temperature, and caffeic acid increased in light roasted and decreased in medium and dark roasted. Green and light roasted coffee extracts promoted higher inhibition of cell viability, caused greater cell cycle arrest in S and G2/M and induced apoptosis more compared to medium and dark roasted coffee extracts and the control samples. Coffee extracts were more effective against DU-145 than in PC-3 cells. Our data provide initial evidence that among the four tested samples, the consumption of green and light coffee extracts contributes to inhibit prostate cancer tumor progression features, potentially preventing aspects related to advanced prostate cancer subtypes. MenosCoffee consumption has been investigated as a protective factor against prostate cancer. Coffee may be related to prostate cancer risk reduction due to its phytochemical compounds, such as caffeine, chlorogenic acids, and trigonelline. The roasting process affects the content of the phytochemicals and undesired compounds can be formed. Microwave-assisted extraction is an alternative to conventional extraction techniques since it preserves more bioactive compounds. Therefore, this study aimed to evaluate the phytochemical composition and the putative preventive effects in prostate cancer development of coffee beans submitted to four different coffee- roasting degrees extracted using microwave-assisted extraction. Coffea arabica green beans (1) were roasted into light (2), medium (3) and dark (4) and these four coffee samples were submitted to microwave-assisted extraction. The antioxidant capacity of these samples was evaluated by five different methods. Caffeine, chlorogenic acid and caffeic acid were measured through HPLC. Samples were tested against PC-3 and DU-145 metastatic prostate cancer cell lines regarding their effects on cell viability, cell cycle progression and apoptotic cell death. We found that green and light roasted coffee extracts had the highest antioxidant activity. Caffeine content was not affected by roasting, chlorogenic acid was degraded due to the temperature, and caffeic acid increased in light roasted and decreased in medium and dark roasted. Green ... Mostrar Tudo |
Palavras-Chave: |
Ácidos clorogênicos; Câncer de próstata; Chlorogenic acids; DU-145; MAE; PC-3; Prostate cancer; Roasting degree. |
Thesagro: |
Café; Câncer; Torrefação. |
Thesaurus NAL: |
Coffee (beverage); Food technology. |
Categoria do assunto: |
Q Alimentos e Nutrição Humana |
Marc: |
LEADER 03357naa a2200421 a 4500 001 2128795 005 2021-03-04 008 2021 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1016/j.foodres.2020.110014$2DOI 100 1 $aMONTENEGRO, J. 245 $aBioactive compounds, antioxidant activity and antiproliferative effects in prostate cancer cells of green and roasted coffee extracts obtained by microwave-assisted extraction (MAE).$h[electronic resource] 260 $c2021 500 $aEpub 2020 Dec 15. 520 $aCoffee consumption has been investigated as a protective factor against prostate cancer. Coffee may be related to prostate cancer risk reduction due to its phytochemical compounds, such as caffeine, chlorogenic acids, and trigonelline. The roasting process affects the content of the phytochemicals and undesired compounds can be formed. Microwave-assisted extraction is an alternative to conventional extraction techniques since it preserves more bioactive compounds. Therefore, this study aimed to evaluate the phytochemical composition and the putative preventive effects in prostate cancer development of coffee beans submitted to four different coffee- roasting degrees extracted using microwave-assisted extraction. Coffea arabica green beans (1) were roasted into light (2), medium (3) and dark (4) and these four coffee samples were submitted to microwave-assisted extraction. The antioxidant capacity of these samples was evaluated by five different methods. Caffeine, chlorogenic acid and caffeic acid were measured through HPLC. Samples were tested against PC-3 and DU-145 metastatic prostate cancer cell lines regarding their effects on cell viability, cell cycle progression and apoptotic cell death. We found that green and light roasted coffee extracts had the highest antioxidant activity. Caffeine content was not affected by roasting, chlorogenic acid was degraded due to the temperature, and caffeic acid increased in light roasted and decreased in medium and dark roasted. Green and light roasted coffee extracts promoted higher inhibition of cell viability, caused greater cell cycle arrest in S and G2/M and induced apoptosis more compared to medium and dark roasted coffee extracts and the control samples. Coffee extracts were more effective against DU-145 than in PC-3 cells. Our data provide initial evidence that among the four tested samples, the consumption of green and light coffee extracts contributes to inhibit prostate cancer tumor progression features, potentially preventing aspects related to advanced prostate cancer subtypes. 650 $aCoffee (beverage) 650 $aFood technology 650 $aCafé 650 $aCâncer 650 $aTorrefação 653 $aÁcidos clorogênicos 653 $aCâncer de próstata 653 $aChlorogenic acids 653 $aDU-145 653 $aMAE 653 $aPC-3 653 $aProstate cancer 653 $aRoasting degree 700 1 $aSANTOS, L. S. dos 700 1 $aSOUZA, R. G. G. de 700 1 $aLIMA, L. G. B. 700 1 $aMATTOS, D. S. 700 1 $aVIANA, B. P. P. B. 700 1 $aBASTOS, A. C. S. da F. 700 1 $aMUZZI, L. 700 1 $aCONTE-JÚNIOR, C. A. 700 1 $aGIMBA, E. R. P. 700 1 $aFREITAS-SILVA, O. 773 $tFood Research International$gv. 140, 110014, 2021.
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