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| Registros recuperados : 220 | |
| 201. |  | CÔA, F.; STRAUSS, M.; CLEMENTE, Z.; RODRIGUES NETO, L. L.; LOPES, J. R.; ALENCAR, R. S.; SOUZA FILHO, A. G.; ALVES, O. L.; CASTRO, V. L. S. S. de; BARBIERI, E.; MARTINEZ, D. S. T. Coating carbon nanotubes with humic acid using an eco-friendly mechanochemical method: Application for Cu(II) ions removal from water and aquatic ecotoxicity. Science of the Total Environment, v. 607-608, p. 1479-1486, 2017.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 202. | | SILVA, G. H. da; CLEMENTE, Z.; COA, F.; RODRIGUES NETO, L. L.; CARVALHO, H. W. P. de; KHAN, L. U.; CASTRO, V. L. S. S. de; MARTINEZ, D. S. T.; MONTEIRO, R. T. R. Avaliação da toxicidade do nanomaterial hibrido tio2@mwcnt em embri. In: WORKSHOP DE NANOTECNOLOGIA APLICADA AO AGRONEGÓCIO, 9., 2017, São Carlos. Anais... São Carlos: Embrapa Instrumentação, 2017. p. 704-707.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 203. | | LUIS, A. I. S.; CAMPOS, E. V. R.; OLIVEIRA, J. L. de; VALLIM, J. H.; PROENÇA, P. L. de F.; CASTANHA, R. F.; CASTRO, V. L. S. S. de; FRACETO, L. F. Ecotoxicity evaluation of polymeric nanoparticles loaded with ascorbic acid for fish nutrition in aquaculture. Journal of Nanobiotechnology, v. 19, n. 1, article 163, 2021. p. 1-22.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 204. | | CASTANHA, R. F.; PEREIRA, A. do E. S.; VILLARREAL, G. P. U.; VALLIM, J. H.; PERTRINI, F. S.; JONSSON, C. M.; FRACETO, L. F.; CASTRO, V. L. S. S. de. Ecotoxicity studies of two atrazine nanoformulations: from the evaluation of stability in media to the effects on aquatic organisms. Environmental Pollution, v. 335, p. 122235, 2023.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 205. | | DURÁN, N.; MARTINEZ, D. S. T.; JUSTO, G. Z.; LIMA, R. de; CASTRO, V. L. S. S. de; UMBUZEIRO, G. de A.; BARBIERI, E.; DURÁN, M.; MELO, P. da S.; ALVES, O. L.; FÁVARO, W. J. Interlab study on nanotoxicology of representative graphene oxide. Journal of Physics, Bristol, v. 617, p. 1-9, 2015. Edition of the proceedings 4th International Conference on Safe Production and Use Nanomaterials (Nanosafe 2014) 18-20 November 2014, held a Grenoble, France.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 206. | | DURÁN, N.; MARTINEZ, D. S. T.; JUSTO, G. Z.; LIMA, R.; CASTRO, V. L. S. S. de; UMBUZEIRO, G. A.; BARBIERI, E.; DURÁN, M.; MELO, P. S.; ALVES, O. L. Interlab study on nanotoxicology of representative graphene oxide. In: INTERNATIONAL CONFERENCE ON SAFE PRODUCTION AND USE OF NANOMATERIALS, 4, 2014, Grenoble. Book of Abstract... Grenoble: Plate-Forme Nano Sécurité, 2014.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 207. | | CASTRO, V. L. S. S. de; JONSSON, C. M.; SILVA, M. S. G. M. e; CASTANHA, R. F.; VALLIM, J. H.; SILVA, L. A. G. da; OLIVEIRA, R. M. D. de; CORREA, D. S.; FERREIRA, M. D. Estimates of AgNP toxicity thresholds in support of environmental safety policies. Journal of Nanoparticle Research, v. 24, n. 1, article 24, 2022.| Biblioteca(s): Embrapa Instrumentação; Embrapa Meio Ambiente. |
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| 208. | | PESSOA, M. C. P. Y.; GHINI, R.; MARQUES, J. F.; SKORUPA, L. A.; BRANDÃO, M. S. B.; CASTRO, V. L. S. S. de; SAITO, M. L.; BETTIOL, W.; FERRAZ, J. M. G. Modelo conceitual de indicadores de sustentabilidade para a microbacia do Córrego Taquara Branca, Sumaré, SP. In: MARQUES, J. F.; SKORUPA, L. A.; FERRAZ, J. M. G. (Ed.). Indicadores de sustentabilidade em agroecossistemas. Jaguariúna: Embrapa Meio Ambiente, 2003. 281 p. Parte II, cap.2, p. 109-113.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 209. | | CASTRO, V. L. S. S. de; CLEMENTE, Z.; JONSSON, C. M.; SILVA, M. S. G. M. e; VALLIM, J. H.; MEDEIROS, A. M. Z. de; MARTINEZ, D. S. T. Nanoecotoxicity assessment of graphene oxide and its relationship with humic acid. Environmental Toxicology and Chemistry, v. 37, n. 7, p. 1998-2012, 2018.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 210. | | MEDEIROS, A. M. Z.; KHAN, L. U.; DELITE, F. S.; COSTA, C. A.; OSPINA, C. A.; ALVES, O. L.; CASTRO, V. L. S. S. de; MARTINEZ, D. S. T. Nanoecotoxicity of GO@AgNPs nanohybrid on zebrafish embryos: influence of natural organic matter and chorion membrane removal. In: INTERNATIONAL CONFERENCE ON HEALTH AND SAFETY ISSUES RELATED TO NANOMATERIALS FOR A SOCIALLY RESPONSIBLE APPROACH - NANOSAFE, 6., 2018, Grenoble. Book of Abstracts... Grenoble: 2018. Ref. A91883DM. p. 116.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 211. | | SILVA, G. H. da; CLEMENTE, Z.; COA, F.; RODRIGUES NETO, L. L.; KHAN, L. U.; CARVALHO, H. W. P.; CASTRO, V. L. S. S. de; MARTINEZ, D. S. T.; MONTEIRO, R. T. R. Nanoecotoxicity and uptake of TiO2@MWCNT hybrid material on Danio rerio embryos. In: BRAZILIAN MRS MEETING, 16., 2017, Gramado. Proceedings... Gramado: Sociedade Brasileira de Pesquisa em Materiais, 2017. Ref. Q.OR3.11. p. 384.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 212. | | KITAMURA, P. C.; SILVEIRA, M. A.; FERRAZ, J. M. G.; BUSCHINELLI, C. C. de A.; CASTRO, V. L. S. S. de; CHAIM, A.; CORRALES, F. M.; MIRANDA, J. I. Pré-diagnóstico agroambiental em microbacia: propostas de intervenção. Jaguariúna: Embrapa Meio Ambiente, 1999. 40p. (Embrapa Meio Ambiente. Documentos, 1)| Biblioteca(s): Embrapa Agrobiologia; Embrapa Agroindústria Tropical; Embrapa Amapá; Embrapa Amazônia Ocidental; Embrapa Amazônia Oriental; Embrapa Arroz e Feijão; Embrapa Clima Temperado; Embrapa Florestas; Embrapa Meio Ambiente; Embrapa Meio Norte / UEP-Parnaíba; Embrapa Meio-Norte; Embrapa Pantanal; Embrapa Roraima; Embrapa Semiárido; Embrapa Soja; Embrapa Solos; Embrapa Suínos e Aves; Embrapa Tabuleiros Costeiros; Embrapa Unidades Centrais; Embrapa Uva e Vinho. MenosEmbrapa Agrobiologia; Embrapa Agroindústria Tropical; Embrapa Amapá; Embrapa Amazônia Ocidental; Embrapa Amazônia Oriental; Embrapa Arroz e Feijão; Embrapa Clima Temperado; Embrapa Florestas; Embrapa Meio Ambiente; Embrapa Meio Norte / UEP-Parnaíba... Mostrar Todas |
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| 213. | | KITAMURA, P. C.; SILVEIRA, M. A.; FERRAZ, J. M. G.; BUSCHINELLI, C. C. de A.; CASTRO, V. L. S. S. de; CHAIM, A.; CORRALES, F. M.; MIRANDA, J. I. Pré-diagnóstico agroambiental em microbacia: propostas de intervenção. Jaguariúna: Embrapa Meio Ambiente, 1999. 40p. (Embrapa Meio Ambiente. Documentos, 1)| Biblioteca(s): Embrapa Territorial. |
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| 214. | | KITAMURA, P. Y.; SILVEIRA, M. A.; FERRAZ, J. M. G.; BUSCHINELLI, C. C. de A.; CASTRO, V. L. S. S. de; CHAIM, A.; CORRALES, F. M.; MIRANDA, J. I. Pre-diagnostico agroambiental em microbacia: propostas de intervencao. Jaguariuna: EMBRAPA-CNPMA, 1999. 40p. (Embrapa Meio Ambiente. Documentos, 1).| Biblioteca(s): Embrapa Cerrados. |
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| 215. | | DE NARDO, E. A. B.; SA, L. A. N. de; CAPALBO, D. M. F.; MORAES, G. J. de; OLIVEIRA, M. C. B. de; CASTRO, V. L. S. S. de; WATANABE, M. A. Protocolo: avaliação de agentes microbianos de controle de pragas para registro como biopesticidas: uma proposta para os órgãos federais registrantes: testes toxicopatológicos em aves, artrópodos benéficos, organismos de solo e plantas. Jaguariúna: Embrapa Meio Ambiente, 1999. 67 p. (Embrapa Meio Ambiente. Documentos, 12).| Biblioteca(s): Embrapa Cerrados; Embrapa Meio Ambiente; Embrapa Soja; Embrapa Unidades Centrais. |
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| 216. | | SILVA, G. H. da; CLEMENTE, Z.; KHAN, L. U.; COA, F.; RODRIGUES NETO, L. L.; CARVALHO, H. W. P. de; CASTRO, V. L. S. S. de; MARTINEZ, D. S. T.; MONTEIRO, R. T. R. Toxicity assessment of TiO2-MWCNT nanohybrid material with enhanced photocatalytic activity on Danio rerio (Zebrafish) embryos. Ecotoxicology and Environmental Safety, v. 165, p. 136-143, 2018.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 217. | | BRAGA, A. P. A.; SOUZA, L. R. de; LIMA, M. G. F.; CRUZ, J. M.; SOUZA, A. C. Z. de; COSTA, M. S.; CASTRO, V. L. S. S. de; MARIN-MORALES, M. A. The Zebrafish as an Alternative Animal Model for Ecotoxicological Research and Testing Brazilian Archives of Biology and Technology, v. 67, e24220968, 2024.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 218. | | LUIS, A. I. S.; CAMPOS, E. V. R.; OLIVEIRA, J. L. de; GUILGER-CASAGRANDE, M.; LIMA, R. de; CASTANHA, R. F.; CASTRO, V. L. S. S. de; FRACETO, L. F. Zein nanoparticles impregnated with eugenol and garlic essential oils for treating fish pathogens. ACS Omega, v. 5, n. 25, p. 15557-15566, 2020.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 219. | | NARDO, E. A. B. de; MORAES G. J. de; CAPALBO, D. M. F.; SA, L. A. N. de; CASTRO, V. L. S. S. de; JONSSON, C. M.; CESNIK, R.; CHAIM, A.; GATTAZ, N. C.; WATANABE, M. A.; MAIA, A. de H. N.; FERREIRA, C. J. A. Análise de risco e impacto ambiental do uso de agentes de controle biológico de pragas. In: ENCONTRO ANUAL DA SECAO BRASILEIRA DA INTERNATIONAL ASSOCIATION FOR IMPACT ASSESSMENT, 4., 1995, Belo Horizonte. Anais... Belo Horizonte: Editora Cultura, 1995. p.365-368| Biblioteca(s): Embrapa Meio Ambiente. |
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| 220. | | DE NARDO, E. A. B.; CAPALBO, D. M. F.; FERREIRA, S.; JONSSON, C. M.; CASTRO, V. L. S. S. de; VALARINI, P. J.; FRIGHETTO, R. T. S.; WATANABE, M. A.; SAITO, M. L.; PARAIBA, L. C.; SA, L. A. N. de; MORAES, G. J. de. Protocolo de avaliação de risco do uso de agentes de controle biológico: uma proposta. In: SIMPÓSIO DE CONTROLE BIOLÓGICO, 4., 1994, Gramado. Anais: Sessão de Posteres. Pelotas: EMBRAPA-CPACT, 1994. p.91 (EMBRAPA-CPACT. Documentos, 5).| Biblioteca(s): Embrapa Meio Ambiente. |
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| Registros recuperados : 220 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
02/02/2016 |
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Data da última atualização: |
02/02/2016 |
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Tipo da produção científica: |
Artigo em Anais de Congresso |
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Autoria: |
DURÁN, N.; MARTINEZ, D. S. T.; JUSTO, G. Z.; LIMA, R. de; CASTRO, V. L. S. S. de; UMBUZEIRO, G. de A.; BARBIERI, E.; DURÁN, M.; MELO, P. da S.; ALVES, O. L.; FÁVARO, W. J. |
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Afiliação: |
NELSON DURAN, IQ-UNICAMP; DIEGO STEFANI TEODORO MARTINEZ, LNNANO-CNPEM; GISELLE ZENKER JUSTO, UNIFESP; RENATA DE LIMA, UNISO; VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; GISELA DE ARAGAO UMBUZEIRO, Faculdade de Tecnologia - UNICAMP; EDSON BARBIERI, Instituto de Pesca - SP; MARCELA DURAN, IQ-UNICAMP; PATRICIA DA SILVA MELO, METROCAMP; OSVALDO LUIZ ALVES, IQ-UNICAMP; WAGNER JOSE FAVARO, IQ-UNICAMP. |
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Título: |
Interlab study on nanotoxicology of representative graphene oxide. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
Journal of Physics, Bristol, v. 617, p. 1-9, 2015. Edition of the proceedings 4th International Conference on Safe Production and Use Nanomaterials (Nanosafe 2014) 18-20 November 2014, held a Grenoble, France. |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: The graphene sample GO:Single-layer graphene oxide, purity 99%, thickness 0.7-1.2 nm (AFM); ~300-800nm X&Y dimensions is the standard size <450 nm & 1-20 ?m lateral dimensions. Cheap Tubes Inc., Bratleboro, USA was selected for our study. Exhaustive characterization of GO was afforded. It exhibited thermal stability over 60oC and it was suspended in deionized water after ultrasonication (1 mg/mL) (stable 10 days). All the biological fluids used in the different assays were used as control of the colloidal suspension stability. Then, all the studies were carried out within that stability period. The cytotoxicity assays were carried out by the Alamar Blue (Resazurin) reduction, MTT and flow cytometry assays in mouse embryonic fibroblast cells (3T3), human keratinocytes (HaCaT), colorectal cancer cells (Caco-2/HCT 116), Lewis lung cancer cells (3LL), acute myeloid leukemia cells (KG-1, Jurkat, Kasumi-1) and chronic myeloid leukemia cells (K562, Lucena) and no significant toxicity was found after exposition to 0.1-100 ug/mL for 24 and 48 h. Breast cancer cells, MCF-7, showed a 20% reduction on cell viability at 24 and 48 h. No cytotoxicity were found in lymphocytes, Chinese hamster ovary cells (CHO) and human macrophage cell line (U937) at 0.1-50 ug/mL, but 30-50% survival inhibition was observed at 100 ug/mL. A dose-dependent increase in apoptosis was observed in some cells (Kasumi-1, Jurkat and K562 cells). In the case of CHO and 3T3 cells, greater levels of necrosis with increasing concentrations of GO (>50 ug/mL) were observed. Genotoxic study using the Comet assay showed slight DNA damage in lymphocytes at all concentrations tested, while more significant effects was observed in CHO cells. Econanotoxicity was carried out by lethality assays in the nematode Caenorhabditis elegans,d in the freshwater coelenterate Hydra, Daphania amd in Shrimp with no signs of toxicity at concentrations varying from 0.1-100 ug/mL of GO. However, death and disintegration of Hydra was observed after exposition to 100 ug/mL for 72 h. In in vivo studies, no changes in biochemical parameters of Fischer 344 rats were observed after the i.p. administration of GO. Some black agglomerates were found in the intraperitoneal cavity of rats injected with GO. However, in Fisher 344 rats-bearing prostate tumors, treatment with GO (up to 100 ug/mL) negatively affected the hepatic parameters, whilst in the renal ones, an improvement was observed. Studies are in progress to understand the mechanisms involved in the uptake of GO by RES. GO appears as a potential non-toxic in vitro and in vivo assays at the concentrations used in this interlab experiments. MenosAbstract: The graphene sample GO:Single-layer graphene oxide, purity 99%, thickness 0.7-1.2 nm (AFM); ~300-800nm X&Y dimensions is the standard size <450 nm & 1-20 ?m lateral dimensions. Cheap Tubes Inc., Bratleboro, USA was selected for our study. Exhaustive characterization of GO was afforded. It exhibited thermal stability over 60oC and it was suspended in deionized water after ultrasonication (1 mg/mL) (stable 10 days). All the biological fluids used in the different assays were used as control of the colloidal suspension stability. Then, all the studies were carried out within that stability period. The cytotoxicity assays were carried out by the Alamar Blue (Resazurin) reduction, MTT and flow cytometry assays in mouse embryonic fibroblast cells (3T3), human keratinocytes (HaCaT), colorectal cancer cells (Caco-2/HCT 116), Lewis lung cancer cells (3LL), acute myeloid leukemia cells (KG-1, Jurkat, Kasumi-1) and chronic myeloid leukemia cells (K562, Lucena) and no significant toxicity was found after exposition to 0.1-100 ug/mL for 24 and 48 h. Breast cancer cells, MCF-7, showed a 20% reduction on cell viability at 24 and 48 h. No cytotoxicity were found in lymphocytes, Chinese hamster ovary cells (CHO) and human macrophage cell line (U937) at 0.1-50 ug/mL, but 30-50% survival inhibition was observed at 100 ug/mL. A dose-dependent increase in apoptosis was observed in some cells (Kasumi-1, Jurkat and K562 cells). In the case of CHO and 3T3 cells, greater levels of necrosis... Mostrar Tudo |
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Palavras-Chave: |
Fraphene oxide; Grafeno; Nanotecnologia. |
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Thesagro: |
Toxidez. |
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Thesaurus NAL: |
Nanomaterials; Nanoparticles; Toxicity. |
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Categoria do assunto: |
S Ciências Biológicas |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/138246/1/2015AA038.pdf
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Marc: |
LEADER 03692nam a2200313 a 4500
001 2035854
005 2016-02-02
008 2015 bl uuuu u00u1 u #d
100 1 $aDURÁN, N.
245 $aInterlab study on nanotoxicology of representative graphene oxide.$h[electronic resource]
260 $aJournal of Physics, Bristol, v. 617, p. 1-9, 2015. Edition of the proceedings 4th International Conference on Safe Production and Use Nanomaterials (Nanosafe 2014) 18-20 November 2014, held a Grenoble, France.$c2015
520 $aAbstract: The graphene sample GO:Single-layer graphene oxide, purity 99%, thickness 0.7-1.2 nm (AFM); ~300-800nm X&Y dimensions is the standard size <450 nm & 1-20 ?m lateral dimensions. Cheap Tubes Inc., Bratleboro, USA was selected for our study. Exhaustive characterization of GO was afforded. It exhibited thermal stability over 60oC and it was suspended in deionized water after ultrasonication (1 mg/mL) (stable 10 days). All the biological fluids used in the different assays were used as control of the colloidal suspension stability. Then, all the studies were carried out within that stability period. The cytotoxicity assays were carried out by the Alamar Blue (Resazurin) reduction, MTT and flow cytometry assays in mouse embryonic fibroblast cells (3T3), human keratinocytes (HaCaT), colorectal cancer cells (Caco-2/HCT 116), Lewis lung cancer cells (3LL), acute myeloid leukemia cells (KG-1, Jurkat, Kasumi-1) and chronic myeloid leukemia cells (K562, Lucena) and no significant toxicity was found after exposition to 0.1-100 ug/mL for 24 and 48 h. Breast cancer cells, MCF-7, showed a 20% reduction on cell viability at 24 and 48 h. No cytotoxicity were found in lymphocytes, Chinese hamster ovary cells (CHO) and human macrophage cell line (U937) at 0.1-50 ug/mL, but 30-50% survival inhibition was observed at 100 ug/mL. A dose-dependent increase in apoptosis was observed in some cells (Kasumi-1, Jurkat and K562 cells). In the case of CHO and 3T3 cells, greater levels of necrosis with increasing concentrations of GO (>50 ug/mL) were observed. Genotoxic study using the Comet assay showed slight DNA damage in lymphocytes at all concentrations tested, while more significant effects was observed in CHO cells. Econanotoxicity was carried out by lethality assays in the nematode Caenorhabditis elegans,d in the freshwater coelenterate Hydra, Daphania amd in Shrimp with no signs of toxicity at concentrations varying from 0.1-100 ug/mL of GO. However, death and disintegration of Hydra was observed after exposition to 100 ug/mL for 72 h. In in vivo studies, no changes in biochemical parameters of Fischer 344 rats were observed after the i.p. administration of GO. Some black agglomerates were found in the intraperitoneal cavity of rats injected with GO. However, in Fisher 344 rats-bearing prostate tumors, treatment with GO (up to 100 ug/mL) negatively affected the hepatic parameters, whilst in the renal ones, an improvement was observed. Studies are in progress to understand the mechanisms involved in the uptake of GO by RES. GO appears as a potential non-toxic in vitro and in vivo assays at the concentrations used in this interlab experiments.
650 $aNanomaterials
650 $aNanoparticles
650 $aToxicity
650 $aToxidez
653 $aFraphene oxide
653 $aGrafeno
653 $aNanotecnologia
700 1 $aMARTINEZ, D. S. T.
700 1 $aJUSTO, G. Z.
700 1 $aLIMA, R. de
700 1 $aCASTRO, V. L. S. S. de
700 1 $aUMBUZEIRO, G. de A.
700 1 $aBARBIERI, E.
700 1 $aDURÁN, M.
700 1 $aMELO, P. da S.
700 1 $aALVES, O. L.
700 1 $aFÁVARO, W. J.
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