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Registros recuperados : 147 | |
101. | | MOREIRA, G. C. M.; BOSCHIERO, C.; CESAR, A. S. M.; REECY, J. M.; GODOY, T. F.; TREVISOLI, P. A.; CANTAO, M. E.; LEDUR, M. C.; IBELLI, A. M. G.; MOURA, A. S. M. T.; GARRICK, D.; COUTINHO, L. L. A genome-wide association study reveals novel genomic regions and positional candidate genes for fat deposition in broiler chickens. BMC Genomics, v. 19, n. 374, 2018. Biblioteca(s): Embrapa Suínos e Aves. |
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102. | | FERNANDES, A. C.; SILVA, V. H. da; GOES, C. P.; MOREIRA, G. C. M.; GODOY, T. F.; IBELLI, A. M. G.; PEIXOTO, J. de O.; CANTAO, M. E.; LEDUR, M. C.; REZENDE, F. M. de; COUTINHO, L. L. Genome-wide detection of CNVs and their association with performance traits in broilers. BMC Genomics, v. 22, n. 354, 2021. Biblioteca(s): Embrapa Suínos e Aves. |
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103. | | JOAQUIM, L. B.; CHUD, T. C. S.; MARCHESI, J. A. P.; SAVEGNAGO, R. P.; BUZANKAS, M. E.; ZANELLA, R.; CANTAO, M. E.; PEIXOTO, J. de O.; LEDUR, M. C.; IRGANG, R.; MUNARI, D. P. Genomic structure of a crossbred landrace pig population. Plos One, v. 14, n.2, e0212266, 2019. Biblioteca(s): Embrapa Suínos e Aves. |
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104. | | PANDOLFI, J. R. C.; IBELLI, A. M. G.; CANTAO, M. E.; PEIXOTO, J. de O.; KRABBE, E. L.; AVILA, V. S. de; KRAMER, B.; ZANELLA, R.; JAENISCH, F. R. F.; MORES, M. A. Z.; COUTINHO, L. L.; LEDUR, M. C. Genetic characterization of poultry gut microbiota by 16S-rRNA gene sequencing. In: CONGRESSO BRASILEIRO DE MICROBIOLOGIA, 28., 2015, Florianópolis. Resumos. Florianópolis: Sociedade Brasileira de Microbiologia, 2015. Biblioteca(s): Embrapa Suínos e Aves. |
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105. | | KOWACIC, R. da C.; IBELLI, A. M. G.; PEIXOTO, J. de O.; MORES, N.; MORES, M. A. Z.; CANTAO, M. E.; SAVOLDI, I. R.; CARMO, K. B. do; COUTINHO, L. L.; LEDUR, M. C. Genes Col16A1 e ANGPT4 são menos expressos em suínos afetados com osteocondrose latens. In: JORNADA DE INICIAÇÃO CIENTÍFICA, 10., 2016, Concórdia. Anais... Concórdia: Embrapa Suínos e Aves: UNC, 2017. p. 15-16. JINC. Biblioteca(s): Embrapa Suínos e Aves. |
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106. | | ROMANO, G. de S.; IBELLI, A. M. G.; PEIXOTO, J. de O.; CANTAO, M. E.; WEBER, T.; MORES, M. A. Z.; MORES, N.; PEDROSA, V. B.; PINTO, L. F. B.; COUTINHO, L. L.; LEDUR, M. C. Genes diferencialmente expressos no transcriptoma de suínos normais e afetados com hérnia escrotal. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 12., 2017, Ribeirão Preto. Anais... Ribeirão Preto: SBMA, 2017. 1 CD-ROM. Biblioteca(s): Embrapa Suínos e Aves. |
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107. | | RODRIGUES, A. F. G.; IBELLI, A. M. G.; PEIXOTO, J. de O.; CANTAO, M. E.; OLIVEIRA, H. C. de; SAVOLDI, I. R.; SOUZA, M. R.; MORES, M. A. Z.; CARREÑO, L. O. D.; LEDUR, M. C. Genes and SNPs Involved with Scrotal and Umbilical Hernia in Pigs. Genes, v. 12, n. 166, 2021. Biblioteca(s): Embrapa Suínos e Aves. |
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108. | | IBELLI, A. M. G.; PEIXOTO, J. de O.; SAVOLDI, I. R.; CARMO, K. B. do; MORES, N.; MORES, M. A. Z.; CANTAO, M. E.; COUTINHO, L. L.; LEDUR, M. C. Biological processes related to ribosome and mitochondrial functions might be involved in the osteochondrosis latens manifestation in gilts. In: WORLD CONGRESS ON GENETICS APPLIED TO LIVESTOCK PRODUCTION, 11., 2018, Auckland, New Zealand. Proceedings... Massey University, 2018. Digital Archive. Biblioteca(s): Embrapa Suínos e Aves. |
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109. | | IBELLI, A. M. G.; PEIXOTO, J. de O.; ZANELLA, R.; GOUVEIA, J. J. de S.; CANTAO, M. E.; COUTINHO, L. L.; MARCHESI, J. A. P.; DAL PIZZOL, M. S.; MARCELINO, D. E. P.; LEDUR, M. C. Downregulation of growth plate genes involved with the onset of femoral head separation in young broilers. Frontiers in Physiology, v. 3, n. 941134, 2022. doi: 10.3389/fphys.2022.941134 Biblioteca(s): Embrapa Suínos e Aves. |
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110. | | DAL PIZZOL, M. S.; IBELLI, A. M. G.; CANTAO, M. E.; CAMPOS, F. G.; OLIVEIRA, H. C. de; PEIXOTO, J. de O.; FERNANDES, L. T.; TAVERNARI, F. de C.; MORES, M. A. Z.; BASTOS, A. P. A.; LEDUR, M. C. Differential expression of miRNAs associated with pectoral myopathies in young broilers: insights from a comparative transcriptome analysis. BMC Genomics, v. 25, n. 104, p. 1-14, 2024. Biblioteca(s): Embrapa Pecuária Sudeste; Embrapa Suínos e Aves. |
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111. | | HUL, L. M.; IBELLI, A. M. G.; SAVOLDI, I. R.; MARCELINO, D. E. P.; FERNANDES, L. T.; PEIXOTO, J. O.; CANTAO, M. E.; HIGA, R. H.; GIACHETTO, P. F.; COUTINHO, L. L.; LEDUR, M. C. Differentially expressed genes in the femur cartilage transcriptome clarify the understanding of femoral head separation in chickens. Scientific Reports, v. 11, n. 1, p. 1-13. 2021. Article number: 17965. Biblioteca(s): Embrapa Agricultura Digital; Embrapa Suínos e Aves. |
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112. | | ZANELLA, R.; CANTAO, M. E.; IBELLI, A. M. G.; PEIXOTO, J. de O.; PANDOLFI, J. R. C.; COUTINHO, L. L.; RHOADS, D. D.; AL-RUBAYE, A.; WIDEMAN, R. F.; LEDUR, M. C. 16s rDNA-metagenomic sequencing of bone lesions caused by femoral head necrosis in broilers. In: PLANT AND ANIMAL GENOME, 22., 2014, San Diego. Abstratcs... San Diego: PAG, 2014. p. 639. Biblioteca(s): Embrapa Suínos e Aves. |
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113. | | IBELLI, A. M. G.; FORNARI, M. B.; NEIS, K. L.; ZANELLA, R.; TESSMANN, A. L.; PANDOLFI, J. R. C.; CANTAO, M. E.; LEDUR, M. C.; PEIXOTO, J. de O. Associations of the osteopontin gene with performance traits in a paternal broiler line. In: CONGRESSO BRASILEIRO DE GENÉTICA, 59., 2013, Águas de Lindóia. Resumos... Ribeirão Preto: SBG, 2013. p. 148. Biblioteca(s): Embrapa Suínos e Aves. |
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114. | | LAGOS, E. B.; PIRES, M. P.; ONO, R. K.; IBELLI, A. M. G.; PEIXOTO, J. de O.; CANTAO, M. E.; MORES, M. A. Z.; FERNANDES, L. T.; PEDROSA, V. B.; LEDUR, M. C. Análise de associação genômica para hérnia umbilical em suínos comerciais utilizando abordagem de marcadores múltiplos. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 13., 2019, Salvador. Anais... Salvador: SBMA, 2019. 1 CD-ROM. Biblioteca(s): Embrapa Suínos e Aves. |
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115. | | SAVOLDI, I. R.; IBELLI, A. M. G.; CANTAO, M. E.; PEIXOTO, J. de O.; MORES, M. A. Z.; LAGOS, E. B.; LOPES, J. S.; ZANELLA, R.; LEDUR, M. C. A joint analysis using exome and transcriptome data identifiescandidate polymorphisms and genes involved with umbilical hernia in pigs. BMC Genomics, v. 22, n. 818, 2021. Biblioteca(s): Embrapa Suínos e Aves. |
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116. | | ZANELLA, J. R. C.; SCHAEFER, R.; GAVA, D.; KLEIN, C. S.; CANTAO, M. E.; SILVA, V. S.; MORES, M. A. Z.; SILVA, M. C. da; MORES, N.; RECH, R. R.; CARON, L. Influenza A virus infection on swine in Brazil. O Biológico, São Paulo, v. 75, p. 32, 2013. Suplemento 2, ref. 30. Edição dos Resumos do 3 Encontro Nacional de Defesa Sanitária Animal, Foz de Iguaçu, dez. 2013. Biblioteca(s): Embrapa Suínos e Aves. |
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117. | | ROMANO, G. de S.; IBELLI, A. M. G.; LORENZETTI, W. R.; WEBER, T.; PEIXOTO, J. de O.; CANTAO, M. E.; MORES, M. A. Z.; MORÉS, N.; PEDROSA, V. B.; COUTINHO. L. L.; LEDUR, M. C. Inguinal ring RNA sequencing reveals downregulation of muscular genes related to scrotal hernia in pigs. Genes, v. 11, n. 117, 2020. Biblioteca(s): Embrapa Suínos e Aves. |
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118. | | MARCHESI, J. A. P.; ONO, R. K.; IBELLI, A. M. G.; BUZANSKAS, M. E.; CANTAO, M. E.; PEIXOTO, J. de O.; MUNARI, D. P.; COUTINHO, L. L.; LEDUR, M. C. Estudo de associação global do genoma revela novos genes e regiões genômicas associadas à conversão alimentar em frangos de corte. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 12., 2017, Ribeirão Preto. Anais... Ribeirão Preto: SBMA, 2017. 1 CD-ROM. Biblioteca(s): Embrapa Suínos e Aves. |
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119. | | ROMANO, G. de S.; IBELLI, A. M. G.; PEIXOTO, J. de O.; CANTAO, M. E.; WEBER, T.; MORES, M. A. Z.; MORES, N.; PEDROSA, V. B.; COUTINHO, L. L.; LEDUR, M. C. Descobertas de variantes envolvidas na ocorrência de hérnia escrotal em suínos pela análise do exoma. In: SIMPÓSIO BRASILEIRO DE MELHORAMENTO ANIMAL, 13., 2019, Salvador. Anais... Salvador: SBMA, 2019. 1 CD-ROM. Biblioteca(s): Embrapa Suínos e Aves. |
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120. | | PEIXOTO, J. de O.; IBELLI, A. M. G.; CANTAO, M. E.; ZANELLA, R.; JAENISCH, F. R. F.; GIACHETTO, P. F.; SETTLES, M. L.; PANDOLFI, J. R. C.; COUTINHO, L. L.; LEDUR, M. C. Expressão gênica diferencial envolvida com condronecrose bacteriana com osteomielite em frangos de corte com 35 dias de idade. In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 52., 2015, Belo Horizonte. Zootecnia: otimizando recursos e potencialidades: anais. Brasília, DF: Sociedade Brasileira de Zootecnia, 2015. Biblioteca(s): Embrapa Agricultura Digital; Embrapa Suínos e Aves. |
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Registros recuperados : 147 | |
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Registro Completo
Biblioteca(s): |
Embrapa Suínos e Aves. |
Data corrente: |
24/09/2018 |
Data da última atualização: |
24/09/2018 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 1 |
Autoria: |
OLIVEIRA FILHO, J. X. de; MORES, M. A. Z.; REBELATTO, R.; KICH, J. D.; CANTAO, M. E.; KLEIN, C. S.; GUEDES, R. M. C.; COLDEBELLA, A.; BARCELLOS, D. E. S. N. de; MORES, N. |
Afiliação: |
JOÃO XAVIER DE OLIVEIRA FILHO; MARCOS ANTONIO ZANELLA MORES, CNPSA; RAQUEL REBELATTO, CNPSA; JALUSA DEON KICH, CNPSA; MAURICIO EGIDIO CANTAO, CNPSA; CATIA SILENE KLEIN, CNPSA; ROBERTO MAURÍCIO CARVALHO GUEDES; ARLEI COLDEBELLA, CNPSA; DAVID EMÍLIO SANTOS NEVES de BARCELLOS; NELSON MORES, CNPSA. |
Título: |
Pathogenic variability among Pasteurella multocida type A isolates from Brazilian pig farms. |
Ano de publicação: |
2018 |
Fonte/Imprenta: |
BMC Veterinary Research, v. 14, n. 244, 2018. |
DOI: |
10.1186/s12917-018-1565-2 |
Idioma: |
Inglês |
Conteúdo: |
Abstract: Background: Pasteurella multocida type A (PmA) is considered a secondary agent of pneumonia in pigs. The role of PmA as a primary pathogen was investigated by challenging pigs with eight field strains isolated from pneumonia and serositis in six Brazilian states. Eight groups of eight pigs each were intranasally inoculated with different strains of PmA (1.5 mL/nostril of 10e7 CFU/mL). The control group (n = 12) received sterile PBS. The pigs were euthanized by electrocution and necropsied by 5 dpi. Macroscopic lesions were recorded, and swabs and fragments of thoracic and abdominal organs were analyzed by bacteriological and pathological assays. The PmA strains were analyzed for four virulence genes (toxA: toxin; pfhA: adhesion; tbpA and hgbB: iron acquisition) by PCR and sequencing and submitted to multilocus sequence typing (MLST). Results: The eight PmA strains were classified as follows: five as highly pathogenic (HP) for causing necrotic bronchopneumonia and diffuse fibrinous pleuritis and pericarditis; one as low pathogenic for causing only focal bronchopneumonia; and two as nonpathogenic because they did not cause injury to any pig. PCR for the gene pfhA was positive for all five HP isolates. Sequencing demonstrated that the pfhA region of the HP strains comprised four genes: tpsB1, pfhA1, tpsB2 and pfhA2. The low and nonpathogenic strains did not contain the genes tpsB2 and pfhA2. A deletion of four bases was observed in the pfhA gene in the low pathogenic strain, and an insertion of 37 kb of phage DNA was observed in the nonpathogenic strains. MLST clustered the HP isolates in one group and the low and nonpathogenic isolates in another. Only the nonpathogenic isolates matched sequence type 10; the other isolates did not match any type available in the MLST database. Conclusions: The hypothesis that some PmA strains are primary pathogens and cause disease in pigs without any co-factor was confirmed. The pfhA region, comprising the genes tpsB1, tpsB2, pfhA1 and pfhA2, is related to the pathogenicity of PmA. The HP strains can cause necrotic bronchopneumonia, fibrinous pleuritis and pericarditis in pigs and can be identified by PCR amplification of the gene pfhA2. MenosAbstract: Background: Pasteurella multocida type A (PmA) is considered a secondary agent of pneumonia in pigs. The role of PmA as a primary pathogen was investigated by challenging pigs with eight field strains isolated from pneumonia and serositis in six Brazilian states. Eight groups of eight pigs each were intranasally inoculated with different strains of PmA (1.5 mL/nostril of 10e7 CFU/mL). The control group (n = 12) received sterile PBS. The pigs were euthanized by electrocution and necropsied by 5 dpi. Macroscopic lesions were recorded, and swabs and fragments of thoracic and abdominal organs were analyzed by bacteriological and pathological assays. The PmA strains were analyzed for four virulence genes (toxA: toxin; pfhA: adhesion; tbpA and hgbB: iron acquisition) by PCR and sequencing and submitted to multilocus sequence typing (MLST). Results: The eight PmA strains were classified as follows: five as highly pathogenic (HP) for causing necrotic bronchopneumonia and diffuse fibrinous pleuritis and pericarditis; one as low pathogenic for causing only focal bronchopneumonia; and two as nonpathogenic because they did not cause injury to any pig. PCR for the gene pfhA was positive for all five HP isolates. Sequencing demonstrated that the pfhA region of the HP strains comprised four genes: tpsB1, pfhA1, tpsB2 and pfhA2. The low and nonpathogenic strains did not contain the genes tpsB2 and pfhA2. A deletion of four bases was observed in the pfhA gene in the low pathogenic ... Mostrar Tudo |
Palavras-Chave: |
Broncopneumonia; PCR; PfhA; Poliserositis; Polyserositis. |
Thesagro: |
Doença Respiratória; Suíno. |
Thesaurus NAL: |
Bronchopneumonia; Multilocus sequence typing; Pathogenicity; Polymerase chain reaction; Respiratory tract diseases; Swine; Virulent strains. |
Categoria do assunto: |
-- |
Marc: |
LEADER 03381naa a2200409 a 4500 001 2096196 005 2018-09-24 008 2018 bl uuuu u00u1 u #d 024 7 $a10.1186/s12917-018-1565-2$2DOI 100 1 $aOLIVEIRA FILHO, J. X. de 245 $aPathogenic variability among Pasteurella multocida type A isolates from Brazilian pig farms.$h[electronic resource] 260 $c2018 520 $aAbstract: Background: Pasteurella multocida type A (PmA) is considered a secondary agent of pneumonia in pigs. The role of PmA as a primary pathogen was investigated by challenging pigs with eight field strains isolated from pneumonia and serositis in six Brazilian states. Eight groups of eight pigs each were intranasally inoculated with different strains of PmA (1.5 mL/nostril of 10e7 CFU/mL). The control group (n = 12) received sterile PBS. The pigs were euthanized by electrocution and necropsied by 5 dpi. Macroscopic lesions were recorded, and swabs and fragments of thoracic and abdominal organs were analyzed by bacteriological and pathological assays. The PmA strains were analyzed for four virulence genes (toxA: toxin; pfhA: adhesion; tbpA and hgbB: iron acquisition) by PCR and sequencing and submitted to multilocus sequence typing (MLST). Results: The eight PmA strains were classified as follows: five as highly pathogenic (HP) for causing necrotic bronchopneumonia and diffuse fibrinous pleuritis and pericarditis; one as low pathogenic for causing only focal bronchopneumonia; and two as nonpathogenic because they did not cause injury to any pig. PCR for the gene pfhA was positive for all five HP isolates. Sequencing demonstrated that the pfhA region of the HP strains comprised four genes: tpsB1, pfhA1, tpsB2 and pfhA2. The low and nonpathogenic strains did not contain the genes tpsB2 and pfhA2. A deletion of four bases was observed in the pfhA gene in the low pathogenic strain, and an insertion of 37 kb of phage DNA was observed in the nonpathogenic strains. MLST clustered the HP isolates in one group and the low and nonpathogenic isolates in another. Only the nonpathogenic isolates matched sequence type 10; the other isolates did not match any type available in the MLST database. Conclusions: The hypothesis that some PmA strains are primary pathogens and cause disease in pigs without any co-factor was confirmed. The pfhA region, comprising the genes tpsB1, tpsB2, pfhA1 and pfhA2, is related to the pathogenicity of PmA. The HP strains can cause necrotic bronchopneumonia, fibrinous pleuritis and pericarditis in pigs and can be identified by PCR amplification of the gene pfhA2. 650 $aBronchopneumonia 650 $aMultilocus sequence typing 650 $aPathogenicity 650 $aPolymerase chain reaction 650 $aRespiratory tract diseases 650 $aSwine 650 $aVirulent strains 650 $aDoença Respiratória 650 $aSuíno 653 $aBroncopneumonia 653 $aPCR 653 $aPfhA 653 $aPoliserositis 653 $aPolyserositis 700 1 $aMORES, M. A. Z. 700 1 $aREBELATTO, R. 700 1 $aKICH, J. D. 700 1 $aCANTAO, M. E. 700 1 $aKLEIN, C. S. 700 1 $aGUEDES, R. M. C. 700 1 $aCOLDEBELLA, A. 700 1 $aBARCELLOS, D. E. S. N. de 700 1 $aMORES, N. 773 $tBMC Veterinary Research$gv. 14, n. 244, 2018.
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