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| Registros recuperados : 83 | |
| Registros recuperados : 83 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
29/11/2017 |
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Data da última atualização: |
29/12/2017 |
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Autoria: |
OLINDA, R. G.; MAIA, L. A.; FRADE, M. T. S.; SOARES, M. P.; BARROS, S. S.; DRIEMEIER, D.; RIET-CORREA, F.; DANTAS, A. F. M. |
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Afiliação: |
Roberio G. Olinda, Programa de Pós-graduação em Medicina Veterinária/Hospital Veterinário/Centro de Saúde e Tecnologia Rural/Universidade Federal de Campina Grande - UFCG; Lisanka A. Maia, Programa de Pós-graduação em Medicina Veterinária/Hospital Veterinário/Centro de Saúde e Tecnologia Rural/Universidade Federal de Campina Grande - UFCG; Maria T. S. Frade, Programa de Pós-graduação em Medicina Veterinária/Hospital Veterinário/Centro de Saúde e Tecnologia Rural/Universidade Federal de Campina Grande - UFCG; Mauro P. Soares, Laboratório Regional de Diagnóstico/Faculdade de Veterinária/Universidade Federal de Pelotas - UFPel; Severo S. Barros, Laboratório Regional de Diagnóstico/Faculdade de Veterinária/Universidade Federal de Pelotas - UFPel; David Driemeier, Departamento de Patologia Clínica Veterinária/Faculdade de Veterinária/Universidade Federal do Rio Grande do Sul - UFRGS; Franklin Riet-Correa, Programa de Pós-graduação em Medicina Veterinária/Hospital Veterinário/Centro de Saúde e Tecnologia Rural/Universidade Federal de Campina Grande - UFCG; Antônio F. M. Dantas, Programa de Pós-graduação em Medicina Veterinária/Hospital Veterinário/Centro de Saúde e Tecnologia Rural/Universidade Federal de Campina Grande - UFCG. |
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Título: |
Degenerative axonopathy associated with copper deficiency in pigs. |
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Ano de publicação: |
2017 |
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Fonte/Imprenta: |
Pesquisa Veterinária Brasileira, Rio de Janeiro, v. 37, n. 9, p. 911-915, setembro. 2017. |
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Idioma: |
Inglês |
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Notas: |
Título em português: Axonopatia degenerativa associada com deficiência de cobre em suínos. |
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Conteúdo: |
The epidemiological, clinic and morphological (pathological and ultrastructural) aspects of four outbreaks of copper deficiency affecting 21- to 90-day-old pigs in the Northeast region of Brazil are reported. Clinical signs began with paraparesis and ataxia and progressed to flaccid or spastic paralysis of the pelvic and thoracic limbs, followed by sternal and/or lateral recumbence. In addition, some animals showed dog-sitting position and intention tremors. The clinical manifestation period was 5-20 days. Significant gross lesions were not observed; however, microscopically, symmetrical degeneration of the white matter with ballooned myelin sheaths containing occasional macrophages was observed, mainly in the spinal cord. Two pigs presented with necrosis ad loss of Purkinje cells and ectopic Purkinje cells in the granular layer and cerebellar white matter. A ultrastructural analysis showed different degrees of damage of myelinated axons in the spinal segments, including an absence of the axoplasm structures with only axonal residues remaining. The myelin sheaths were degenerated and often collapsed into the space previously occupied by the axon. These results suggest that myelin degeneration is secondary to the axonal lesion. Finally, the concentration of copper in the liver was determined using atomic absorption spectrophotometry and was found to be low (ranging from 2.2 to 10.8 ppm). In conclusion, in the Brazilian semiarid region, Cu deficiency occurs in 21 to 90-day-old pigs that ingested different types of waste in their food. MenosThe epidemiological, clinic and morphological (pathological and ultrastructural) aspects of four outbreaks of copper deficiency affecting 21- to 90-day-old pigs in the Northeast region of Brazil are reported. Clinical signs began with paraparesis and ataxia and progressed to flaccid or spastic paralysis of the pelvic and thoracic limbs, followed by sternal and/or lateral recumbence. In addition, some animals showed dog-sitting position and intention tremors. The clinical manifestation period was 5-20 days. Significant gross lesions were not observed; however, microscopically, symmetrical degeneration of the white matter with ballooned myelin sheaths containing occasional macrophages was observed, mainly in the spinal cord. Two pigs presented with necrosis ad loss of Purkinje cells and ectopic Purkinje cells in the granular layer and cerebellar white matter. A ultrastructural analysis showed different degrees of damage of myelinated axons in the spinal segments, including an absence of the axoplasm structures with only axonal residues remaining. The myelin sheaths were degenerated and often collapsed into the space previously occupied by the axon. These results suggest that myelin degeneration is secondary to the axonal lesion. Finally, the concentration of copper in the liver was determined using atomic absorption spectrophotometry and was found to be low (ranging from 2.2 to 10.8 ppm). In conclusion, in the Brazilian semiarid region, Cu deficiency occurs in 21 to 90-day-old... Mostrar Tudo |
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Palavras-Chave: |
Axonal degeneration; Copper deficiency; Deficiência de cobre; Degeneração axonal; Degeneração da mielina; Degenerative myelopathy; Mielopatia; Mineral deficiency; Myelin degeneration. |
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Thesagro: |
Deficiência mineral; Suíno. |
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Thesaurus NAL: |
Swine. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/167711/1/Degenerative-axonopatht-associated.pdf
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Marc: |
LEADER 02693naa a2200361 a 4500
001 2080967
005 2017-12-29
008 2017 bl uuuu u00u1 u #d
100 1 $aOLINDA, R. G.
245 $aDegenerative axonopathy associated with copper deficiency in pigs.$h[electronic resource]
260 $c2017
500 $aTítulo em português: Axonopatia degenerativa associada com deficiência de cobre em suínos.
520 $aThe epidemiological, clinic and morphological (pathological and ultrastructural) aspects of four outbreaks of copper deficiency affecting 21- to 90-day-old pigs in the Northeast region of Brazil are reported. Clinical signs began with paraparesis and ataxia and progressed to flaccid or spastic paralysis of the pelvic and thoracic limbs, followed by sternal and/or lateral recumbence. In addition, some animals showed dog-sitting position and intention tremors. The clinical manifestation period was 5-20 days. Significant gross lesions were not observed; however, microscopically, symmetrical degeneration of the white matter with ballooned myelin sheaths containing occasional macrophages was observed, mainly in the spinal cord. Two pigs presented with necrosis ad loss of Purkinje cells and ectopic Purkinje cells in the granular layer and cerebellar white matter. A ultrastructural analysis showed different degrees of damage of myelinated axons in the spinal segments, including an absence of the axoplasm structures with only axonal residues remaining. The myelin sheaths were degenerated and often collapsed into the space previously occupied by the axon. These results suggest that myelin degeneration is secondary to the axonal lesion. Finally, the concentration of copper in the liver was determined using atomic absorption spectrophotometry and was found to be low (ranging from 2.2 to 10.8 ppm). In conclusion, in the Brazilian semiarid region, Cu deficiency occurs in 21 to 90-day-old pigs that ingested different types of waste in their food.
650 $aSwine
650 $aDeficiência mineral
650 $aSuíno
653 $aAxonal degeneration
653 $aCopper deficiency
653 $aDeficiência de cobre
653 $aDegeneração axonal
653 $aDegeneração da mielina
653 $aDegenerative myelopathy
653 $aMielopatia
653 $aMineral deficiency
653 $aMyelin degeneration
700 1 $aMAIA, L. A.
700 1 $aFRADE, M. T. S.
700 1 $aSOARES, M. P.
700 1 $aBARROS, S. S.
700 1 $aDRIEMEIER, D.
700 1 $aRIET-CORREA, F.
700 1 $aDANTAS, A. F. M.
773 $tPesquisa Veterinária Brasileira, Rio de Janeiro$gv. 37, n. 9, p. 911-915, setembro. 2017.
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Embrapa Unidades Centrais (AI-SEDE) |
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