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| 19. |  | LOPES, J.; MADEIRA, N. R. Avaliação de fitotoxidez de linuron, fluazifop-p-butil e metribuzin em mandioquinha-salsa. Horticultura Brasileira, Brasília, DF, v. 27, n. 2, p. S3971-S3975, ago. 2009. CD-ROM. Suplemento. Trabalho apresentado no 49. Congresso Brasileiro de Olericultura, Águas de Lindóia, SP.| Biblioteca(s): Embrapa Hortaliças. |
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| Registros recuperados : 235 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Agroindústria de Alimentos; Embrapa Amazônia Ocidental. |
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Data corrente: |
04/04/2013 |
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Data da última atualização: |
14/12/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
AZEVEDO, M. M. B.; CHAVES, F. C. M.; ALMEIDA, C. A.; BIZZO, H. R.; DUARTE, R. S.; CAMPOS-TAKAKI, G. M.; ALVIANO, C. S.; ALVIANO, D. S. |
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Afiliação: |
Mariana M. B. Azevedo, UFRJ; FRANCISCO CELIO MAIA CHAVES, CPAA; Catia A. Almeida, IMPG-UFRJ; HUMBERTO RIBEIRO BIZZO, CTAA; Rafael S. Duarte, IMPG-UFRJ; Galba M. Campos-Takaki, Catholic University of Pernambuco; Celuta S. Alviano, IMPG-UFRJ; Daniela S. Alviano, IMPG-UFRJ. |
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Título: |
Antioxidant and Antimicrobial Activities of 7-Hydroxy-calamenene-Rich Essential Oils from Croton cajucara Benth. |
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Ano de publicação: |
2013 |
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Fonte/Imprenta: |
Molecules, v. 18, n. 1, p. 1128-1137, jan. 2013. |
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ISSN: |
1420-3049 |
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DOI: |
10.3390/molecules18011128 |
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Idioma: |
Inglês |
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Conteúdo: |
Croton cajucara is a shrub native to the Amazon region locally known as ?sacaca?. Two morphotypes are known: white and red ?sacaca?. The essential oils (EO) obtained by hydrodistillation from leaves of the red morphotype were, in general, rich in 7-hydroxycalamenene (28.4%?37.5%). The effectiveness of these EO regarding the antimicrobial activity against pathogenic microorganisms was initially investigated by the drop test method, showing significant inhibition zones. Among the microorganisms tested, the essential oils rich in 7-hydroxycalamenene were more effective against methicillin resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Mycobacterium tuberculosis, M. smegmatis, Mucor circinelloides and Rhizopus oryzae. The minimum inhibitory concentrations (MIC) of the oils were determined using the broth dilution assay. It was possible to observe that 7-hydroxycalamenene-rich oils presented high antimicrobial activity, with MIC of 4.76 × 10−3 μg/mL for MRSA, 4.88 μg/mL for M. tuberculosis, 39.06 μg/mL for M. smegmatis, and 0.152 μg/mL for R. oryzae and 3.63 × 10−8 μg/mL for M. circinelloides. The antioxidant activity of this EO suggests that 7-hydroxycalamenene provides more antioxidant activity according with EC50 less than 63.59 μg/mL. Considering the bioactive potential of EOs and 7-hydroxycalamenene could be of great interest for development of antimicrobials for therapeutic use in treatment of bacterial and fungal infections in humans and/or veterinary practice. MenosCroton cajucara is a shrub native to the Amazon region locally known as ?sacaca?. Two morphotypes are known: white and red ?sacaca?. The essential oils (EO) obtained by hydrodistillation from leaves of the red morphotype were, in general, rich in 7-hydroxycalamenene (28.4%?37.5%). The effectiveness of these EO regarding the antimicrobial activity against pathogenic microorganisms was initially investigated by the drop test method, showing significant inhibition zones. Among the microorganisms tested, the essential oils rich in 7-hydroxycalamenene were more effective against methicillin resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Mycobacterium tuberculosis, M. smegmatis, Mucor circinelloides and Rhizopus oryzae. The minimum inhibitory concentrations (MIC) of the oils were determined using the broth dilution assay. It was possible to observe that 7-hydroxycalamenene-rich oils presented high antimicrobial activity, with MIC of 4.76 × 10−3 μg/mL for MRSA, 4.88 μg/mL for M. tuberculosis, 39.06 μg/mL for M. smegmatis, and 0.152 μg/mL for R. oryzae and 3.63 × 10−8 μg/mL for M. circinelloides. The antioxidant activity of this EO suggests that 7-hydroxycalamenene provides more antioxidant activity according with EC50 less than 63.59 μg/mL. Considering the bioactive potential of EOs and 7-hydroxycalamenene could be of great interest for development of antimicrobials for therapeutic use in treatment of bacterial and fungal in... Mostrar Tudo |
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Palavras-Chave: |
Atividade antimicrobiana; Atividade antioxidante; Óleos essenciais; Sacaca. |
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Thesagro: |
Óleo Essencial. |
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Thesaurus NAL: |
Croton cajucara. |
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Categoria do assunto: |
--
X Pesquisa, Tecnologia e Engenharia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/80491/1/molecules-18-01128.pdf
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/88878/1/2013-060.pdf
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Marc: |
LEADER 02431naa a2200301 a 4500
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008 2013 bl uuuu u00u1 u #d
022 $a1420-3049
024 7 $a10.3390/molecules18011128$2DOI
100 1 $aAZEVEDO, M. M. B.
245 $aAntioxidant and Antimicrobial Activities of 7-Hydroxy-calamenene-Rich Essential Oils from Croton cajucara Benth.
260 $c2013
520 $aCroton cajucara is a shrub native to the Amazon region locally known as ?sacaca?. Two morphotypes are known: white and red ?sacaca?. The essential oils (EO) obtained by hydrodistillation from leaves of the red morphotype were, in general, rich in 7-hydroxycalamenene (28.4%?37.5%). The effectiveness of these EO regarding the antimicrobial activity against pathogenic microorganisms was initially investigated by the drop test method, showing significant inhibition zones. Among the microorganisms tested, the essential oils rich in 7-hydroxycalamenene were more effective against methicillin resistant Staphylococcus aureus (MRSA), Enterococcus faecalis, Mycobacterium tuberculosis, M. smegmatis, Mucor circinelloides and Rhizopus oryzae. The minimum inhibitory concentrations (MIC) of the oils were determined using the broth dilution assay. It was possible to observe that 7-hydroxycalamenene-rich oils presented high antimicrobial activity, with MIC of 4.76 × 10−3 μg/mL for MRSA, 4.88 μg/mL for M. tuberculosis, 39.06 μg/mL for M. smegmatis, and 0.152 μg/mL for R. oryzae and 3.63 × 10−8 μg/mL for M. circinelloides. The antioxidant activity of this EO suggests that 7-hydroxycalamenene provides more antioxidant activity according with EC50 less than 63.59 μg/mL. Considering the bioactive potential of EOs and 7-hydroxycalamenene could be of great interest for development of antimicrobials for therapeutic use in treatment of bacterial and fungal infections in humans and/or veterinary practice.
650 $aCroton cajucara
650 $aÓleo Essencial
653 $aAtividade antimicrobiana
653 $aAtividade antioxidante
653 $aÓleos essenciais
653 $aSacaca
700 1 $aCHAVES, F. C. M.
700 1 $aALMEIDA, C. A.
700 1 $aBIZZO, H. R.
700 1 $aDUARTE, R. S.
700 1 $aCAMPOS-TAKAKI, G. M.
700 1 $aALVIANO, C. S.
700 1 $aALVIANO, D. S.
773 $tMolecules$gv. 18, n. 1, p. 1128-1137, jan. 2013.
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Registro original: |
Embrapa Amazônia Ocidental (CPAA) |
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