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| Registros recuperados : 6 | |
| 1. |  | SOUZA, F. V. D.; SOUZA, E. H. de; SENA NETO, A. R.; MARCONCINI, J. M.; ASSIS, S. A. de. Production for other uses In: SANEWSKI, G. M.; BARTHOLOMEW, D. P.; PAULL, R. E. (ed.). The Pineapple,: Botany, Production and Uses. 2nd Edition. Boston, MA: CABI, 2018. Cap, 10. p. 222-232.| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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| 2. | | OLIVEIRA, T. S. de; SENA, A. R. de; ASSIS, S. A.; TESHIMA, E.; DAVID, J. M.; LEDO, C. A. da S. Análise disriminante multivariada para caracterização física de diferentes estádios de maturação de frutos de jamelão (Syzygium cumini Lamarck). In: CONGRESSO BRASILEIRO DE FRUTICULTURA, 20.; ANNUAL MEETING OF THE INTERAMERICAN SOCIETY FOR TROPICAL HORTICULTURE, 54., 2008, Vitória. Frutas para todos: estratégias, tecnologias e visão sustentável: anais. Vitória: INCAPER: Sociedade Brasileira de Fruticultura, 2008.| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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| 3. | | PAULO, E. M.; VASCONCELOS, M. P.; OLIVEIRA, I. S.; AFFE, H. M. J.; NASCIMENTO, R. dos S.; MELO, I. S. de; ROQUE, M. R. de A.; ASSIS, S. A. de. An alternative method for screening lactic acid bacteria for the production of exopolysaccharides with rapid confirmation. Ciência e Tecnologia de Alimentos, Campinas, v. 32, n. 4, p. 710-714, 2012.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 4. | | MIRANDA, Í. K. S. P. B.; MIRANDA, A. F. S.; SOUZA, F. V. D.; PIROVANI, C. P.; PEPE, I. M.; RODOWANSKI, I. J.; FERREIRA, K. T. de S. E.; VAZ, L. M. S.; ASSIS, S. A. de. The biochemical characterization, stabilization studies and the antiproliferative effect of bromelain against B16F10 murine melanoma cells. International Journal of Food Sciences and Nutrition, 2016| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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| 5. | | MIRANDA, Í. K. S. P. B.; SANTANA, F. R.; CAMILLOTO, G. P.; DETONI, C. B.; SOUZA, F. V. D.; CABRAL-ALBUQUERQUE, E. C. de M.; ALVES, S. L.; NECO, G. L.; LIMA, F. O. de; ASSIS, S. A. de. Development of membranes based on carboxymethyl cellulose/acetylated arrowroot starch containing bromelain extract carried on nanoparticles and liposomes. Journal of Pharmaceutical Sciences, 2021. Online first.| Biblioteca(s): Embrapa Mandioca e Fruticultura. |
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| 6. | | PAULO, E. M.; BOFFO, E. F.; BRANCO, A.; VALENTE, A. M. M. P.; MELO, I. S. de; FERREIRA, A. G.; ROQUE, M. R. de A.; ASSIS, S. A. de. Production, extraction and characterization of exopolysaccharides produced by the native Leuconostoc pseudomesenteroides R2 strain. Anais da Academia Brasileira de Ciências, Rio de Janeiro, v. 84, n. 2, p. 495-507, 2012.| Biblioteca(s): Embrapa Meio Ambiente. |
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| Registros recuperados : 6 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Mandioca e Fruticultura. Para informações adicionais entre em contato com cnpmf.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Mandioca e Fruticultura. |
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Data corrente: |
24/12/2016 |
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Data da última atualização: |
07/02/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
B - 1 |
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Autoria: |
MIRANDA, Í. K. S. P. B.; MIRANDA, A. F. S.; SOUZA, F. V. D.; PIROVANI, C. P.; PEPE, I. M.; RODOWANSKI, I. J.; FERREIRA, K. T. de S. E.; VAZ, L. M. S.; ASSIS, S. A. de. |
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Afiliação: |
ÍNGARA KEISLE SÃO PAULO BARRETTO MIRANDA; ANDERSON FONTES SUZART MIRANDA; FERNANDA VIDIGAL DUARTE SOUZA, CNPMF; CARLOS PRIMINHO PIROVANI; IURI MUNIZ PEPE; IVANOÉ JOÃO RODOWANSKI; KATIÚCIA TÍCILA DE SOUZA EDUVIRGENS FERREIRA; LUCIANO MENDES SOUZA VAZ; SANDRA APARECIDA DE ASSIS. |
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Título: |
The biochemical characterization, stabilization studies and the antiproliferative effect of bromelain against B16F10 murine melanoma cells. |
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Ano de publicação: |
2016 |
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Fonte/Imprenta: |
International Journal of Food Sciences and Nutrition, 2016 |
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ISSN: |
0963-7486 |
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Idioma: |
Português |
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Conteúdo: |
The current study aims to extract bromelain from different parts (stem, crown, peels, pulp and leaves) of Ananas comosus var. comosus AGB 772; to determine of optimum pH and temperature; to test bromelain stability in disodium EDTA and sodium benzoate, and to investigate its pharmacological activity on B16F10 murine melanoma cells in vitro. The highest enzymatic activity was found in bromelain extracted from the pulp and peel. The optimum bromelain pH among all studied pineapple parts was 6.0. The optimum temperature was above 50?°C in all bromelain extracts. The fluorescence analysis confirmed the stability of bromelain in the presence of EDTA and sodium benzoate. Bromelain was pharmacologically active against B16F10 melanoma cells and it was possible verifying approximately 100% inhibition of tumor cell proliferation in vitro. Since bromelain activity was found in different parts of pineapple plants, pineapple residues from the food industry may be used for bromelain extraction. |
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Thesagro: |
Bromélia. |
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Categoria do assunto: |
-- |
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Marc: |
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001 2059254
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008 2016 bl uuuu u00u1 u #d
022 $a0963-7486
100 1 $aMIRANDA, Í. K. S. P. B.
245 $aThe biochemical characterization, stabilization studies and the antiproliferative effect of bromelain against B16F10 murine melanoma cells.$h[electronic resource]
260 $c2016
520 $aThe current study aims to extract bromelain from different parts (stem, crown, peels, pulp and leaves) of Ananas comosus var. comosus AGB 772; to determine of optimum pH and temperature; to test bromelain stability in disodium EDTA and sodium benzoate, and to investigate its pharmacological activity on B16F10 murine melanoma cells in vitro. The highest enzymatic activity was found in bromelain extracted from the pulp and peel. The optimum bromelain pH among all studied pineapple parts was 6.0. The optimum temperature was above 50?°C in all bromelain extracts. The fluorescence analysis confirmed the stability of bromelain in the presence of EDTA and sodium benzoate. Bromelain was pharmacologically active against B16F10 melanoma cells and it was possible verifying approximately 100% inhibition of tumor cell proliferation in vitro. Since bromelain activity was found in different parts of pineapple plants, pineapple residues from the food industry may be used for bromelain extraction.
650 $aBromélia
700 1 $aMIRANDA, A. F. S.
700 1 $aSOUZA, F. V. D.
700 1 $aPIROVANI, C. P.
700 1 $aPEPE, I. M.
700 1 $aRODOWANSKI, I. J.
700 1 $aFERREIRA, K. T. de S. E.
700 1 $aVAZ, L. M. S.
700 1 $aASSIS, S. A. de
773 $tInternational Journal of Food Sciences and Nutrition, 2016
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