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| Registros recuperados : 5 | |
| 1. |  | ASSIS, H. C. S. de; SILVA, C. A. da; OBA, E. T.; PAMPLONA, J. H.; MELA, M.; DORIA, H. B.; GUILOSKI, I. C.; RAMSDORF, W.; CESTARI, M. M. Hematologic and hepatic responses of the freshwater fish Hoplias malabaricus after saxitoxin exposure. Toxicon, Oxford, v. 66, p. 25-30, 2013.| Biblioteca(s): Embrapa Amapá. |
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| 2. | | SILVA, C. A. da; OBA, E. T.; RAMSDORF, W. A.; MAGALHÃES, V. F.; CESTARI, M. M.; RIBEIRO, C. A. O.; ASSIS, H. C. S. de. First report about saxitoxins in freshwater fish Hoplias malabaricus through trophic exposure. Toxicon, Oxford, v. 57, n. 1, p. 141-147, jan. 2011.| Biblioteca(s): Embrapa Amapá. |
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| 3. | | BASTOS, L. R. S.; BASTOS, L. P.; CARNEIRO, P. C. F.; GUILOSKI, I. C.; ASSIS, H. C. S. de; PADIAL, A. A.; FREIRE, C. A. Evaluation of the water quality of the upper reaches of the main Southern Brazil river (Iguaçu river) through in situ exposure of the native siluriform Rhamdia quelen in cages. Environmental Pollution, v. 231, n. 2, 2017.| Biblioteca(s): Embrapa Tabuleiros Costeiros. |
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| 4. | | RIBEIRO, S. C.; MALHEIROS, D. F.; GUILOZKI, I. C.; MAJOLO, C.; CHAVES, F. C. M.; CHAGAS, E. C.; ASSIS, H. C. S. de; TAVARES-DIAS, M.; YOSHIOKA, E. T. O. Antioxidants effects and resistance against pathogens of Colossoma macropomum (Serassalmidae) fed Mentha piperita essential oil. Aquaculture, v. 490, p. 29-34, Jan. 2018.| Biblioteca(s): Embrapa Amapá; Embrapa Amazônia Ocidental. |
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| 5. | | PAMPLONA, J. H.; OBA, E. T.; SILVA, T. A.; RAMOS, L. P.; RAMSDORF, W. A.; CESTARI, M. M.; RIBEIRO, C. A. O.; ZAMPRONIO, A. R.; ASSIS, H. C. S. de. Subchronic effects of dipyrone on the fish species Rhamdia quelen. Ecotoxicology and Environmental Safety, v. 74, n. 3, p. 342-349, Mar. 2011.| Biblioteca(s): Embrapa Amapá. |
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| Registros recuperados : 5 | |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Amapá. Para informações adicionais entre em contato com cpafap.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Amapá. |
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Data corrente: |
03/10/2011 |
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Data da última atualização: |
28/11/2017 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
PAMPLONA, J. H.; OBA, E. T.; SILVA, T. A.; RAMOS, L. P.; RAMSDORF, W. A.; CESTARI, M. M.; RIBEIRO, C. A. O.; ZAMPRONIO, A. R.; ASSIS, H. C. S. de. |
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Afiliação: |
J.H. PAMPLONA, UFPR; ELIANE TIE OBA YOSHIOKA, CPAF-AP; T.A. DA SILVA, UFPR; L. P. RAMOS, UFPR; W. A. RAMSDORF, UFPR; M. M. CESTARI, UFPR; C. A. O. RIBEIRO, UFPR; A. R. ZAMPRONIO, UFPR; H. C. S. DE ASSIS, UFPR. |
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Título: |
Subchronic effects of dipyrone on the fish species Rhamdia quelen. |
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Ano de publicação: |
2011 |
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Fonte/Imprenta: |
Ecotoxicology and Environmental Safety, v. 74, n. 3, p. 342-349, Mar. 2011. |
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Idioma: |
Inglês |
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Conteúdo: |
The use of the non-steroidal anti-inflammatory drugs such as dipyrone is so widespread that this drug and its metabolites have been detected in effluents and surface water. This study aimed to evaluate the potential toxic effects of dipyrone on the aquatic environment, using a native fish species, Rhamdia quelen. Fish were exposed to three concentrations of dipyrone, 0.5, 5 and 50 mg/L, in the water for 15 days, and hematological, biochemical, genetic and morphological biomarkers were evaluated. The glutathione S-transferase activity decreased in the highest concentration in relation to the control group. In addition, hematocrit, red blood cells and thrombocyte counts were decreased in all three exposed groups in relation to the control group. The comet assay showed DNA damage at the lowest concentration of dipyrone and significant kidney damage. Those results suggest that a constant exposure of aquatic organisms to dipyrone presents potential toxic effects. |
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Thesagro: |
Bagre; Peixe de água doce. |
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Categoria do assunto: |
S Ciências Biológicas |
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Marc: |
LEADER 01670naa a2200241 a 4500
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100 1 $aPAMPLONA, J. H.
245 $aSubchronic effects of dipyrone on the fish species Rhamdia quelen.$h[electronic resource]
260 $c2011
520 $aThe use of the non-steroidal anti-inflammatory drugs such as dipyrone is so widespread that this drug and its metabolites have been detected in effluents and surface water. This study aimed to evaluate the potential toxic effects of dipyrone on the aquatic environment, using a native fish species, Rhamdia quelen. Fish were exposed to three concentrations of dipyrone, 0.5, 5 and 50 mg/L, in the water for 15 days, and hematological, biochemical, genetic and morphological biomarkers were evaluated. The glutathione S-transferase activity decreased in the highest concentration in relation to the control group. In addition, hematocrit, red blood cells and thrombocyte counts were decreased in all three exposed groups in relation to the control group. The comet assay showed DNA damage at the lowest concentration of dipyrone and significant kidney damage. Those results suggest that a constant exposure of aquatic organisms to dipyrone presents potential toxic effects.
650 $aBagre
650 $aPeixe de água doce
700 1 $aOBA, E. T.
700 1 $aSILVA, T. A.
700 1 $aRAMOS, L. P.
700 1 $aRAMSDORF, W. A.
700 1 $aCESTARI, M. M.
700 1 $aRIBEIRO, C. A. O.
700 1 $aZAMPRONIO, A. R.
700 1 $aASSIS, H. C. S. de
773 $tEcotoxicology and Environmental Safety$gv. 74, n. 3, p. 342-349, Mar. 2011.
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