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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
22/06/2022 |
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Data da última atualização: |
10/03/2023 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
FIGUEIREDO, A.; ANHOLETO, L. A.; COLA, D. F.; FANTATTO, R. R.; SANTOS, I. B.; ALEMÁN GAINZA, Y.; SOUSA, G. A.; PICKETT, L. J.; FRACETO, L. F.; CHAGAS, A. C. de S. |
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Afiliação: |
AMANDA FIGUEIREDO, UNESP; LUÍS ADRIANO ANHOLETO, UNESP; DIEGO FARIA COLA, UNESP; RAFAELA REGINA FANTATTO, UNESP; ISABELLA BARBOSA SANTOS, UNESP; YOUSMEL ALEMÁN GAINZA, UNESP; GUSTAVO AVELAR SOUSA, UNESP; LAURA JANE PICKETT, Acadia University; LEONARDO FERNANDES FRACETO, UNESP; ANA CAROLINA DE SOUZA CHAGAS, CPPSE. |
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Título: |
Nanoformulations with synthetic and plant-derived compounds for cattle tick control. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Veterinary Parasitology, v. 309, Sep. 2022, 109756. |
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Páginas: |
9 p. |
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DOI: |
https://doi.org/10.1016/j.vetpar.2022.109756 |
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Idioma: |
Inglês |
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Conteúdo: |
Nanocarriers of acaricidal compounds improve the bioavailability, absorption, and tissue distribution of active ingredients, releasing them in a slow, targeted way and protecting them against premature degradation. Thus, this study aimed to develop formulations from solid lipid nanoparticles (SLN), or nanostructured lipid carriers (NLC) associated with cypermethrin (cip) + chlorpyrifos (chlo) and vegetable compounds (citral, menthol, or limonene). Particles were then characterised, and their efficacy was verified on R. microplus in comparison to nanoformulations without the plant-based compounds. Six different formulations were developed and characterised by dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA). Formulations 1 (SLN+cyp+chlo+citral), 2 (SLN+cyp+chlo+menthol), 3 (SLN+cyp+chlo+limonene), 4 (NLC+cyp+chlo+citral), 5 (NLC+cyp+chlo+menthol) and 6 (NLC+cyp+chlo+limonene) had mean diameters from 286 to 304 nm; polydispersion from 0.16 to 0.18; zeta potential from ?15.8 to −20 mV, concentration from 3.37 ± 0.24 × 1013 to 5.44 ± 0.18 × 1013 particles/mL and encapsulation efficiency (EE) > 98.01 % for all active ingredients. All formulations were evaluated for their acaricidal potential by the larval packet test (LPT) and compared with nanoformulations without the plant-based compounds. Formulations were also compared with positive (Colosso® at 512 µg/mL) and negative controls (distilled water and nanoparticles without active ingredients). The SLN (1, 2 and 3) and NLC (4, 5 and 6) formulations, at 7 µg/mL, resulted in 90.4 % , 75.9 % , 93.8 % , 100 % , 95.1 % and 72.7 % mortality. The data demonstrated that the addition of citral, menthol or limonene in the formulations improved their acaricide action against tick larvae. Except for formulation 4, for which it was not possible to determine lethal concentrations (LC). Formulations, 1, 2, 3, 5 and 6 reached LC50 and LC90 values of 3.3 and 7.2, 5.4 and 9.2, 4.0 and 8.1, 2.3 and 5.4 as well as 5.5 and 9.4 µg/mL, respectively. It was possible to encapsulate the active ingredients and characterise the lipid carrier systems. SLN and NLC protected the active ingredients against degradation in solution and increased the overall stability. A stabile solution is necessary for synthesizing commercial acaricidal products. It is hoped that these findings may contribute to new studies focused on the use of nanocarriers in tick formulations. By reducing the amount or concentration of active ingredients within commercial products, the risk of residues presents in food of animal origin or remaining in the environment is reduced. Nanocarriers help prevent these challenges, while still maintaining effective parasitic control. Utilizing a combination of natural and synthetic products can be part of integrated management solutions and can help overcome widespread acaricide resistance in populations of cattle ticks. MenosNanocarriers of acaricidal compounds improve the bioavailability, absorption, and tissue distribution of active ingredients, releasing them in a slow, targeted way and protecting them against premature degradation. Thus, this study aimed to develop formulations from solid lipid nanoparticles (SLN), or nanostructured lipid carriers (NLC) associated with cypermethrin (cip) + chlorpyrifos (chlo) and vegetable compounds (citral, menthol, or limonene). Particles were then characterised, and their efficacy was verified on R. microplus in comparison to nanoformulations without the plant-based compounds. Six different formulations were developed and characterised by dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA). Formulations 1 (SLN+cyp+chlo+citral), 2 (SLN+cyp+chlo+menthol), 3 (SLN+cyp+chlo+limonene), 4 (NLC+cyp+chlo+citral), 5 (NLC+cyp+chlo+menthol) and 6 (NLC+cyp+chlo+limonene) had mean diameters from 286 to 304 nm; polydispersion from 0.16 to 0.18; zeta potential from ?15.8 to −20 mV, concentration from 3.37 ± 0.24 × 1013 to 5.44 ± 0.18 × 1013 particles/mL and encapsulation efficiency (EE) > 98.01 % for all active ingredients. All formulations were evaluated for their acaricidal potential by the larval packet test (LPT) and compared with nanoformulations without the plant-based compounds. Formulations were also compared with positive (Colosso® at 512 µg/mL) and negative controls (distilled water and nanoparticles without active ingredients). The SL... Mostrar Tudo |
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Palavras-Chave: |
Cattle tick; Nanostructured lipid carriers; Plant isolates; Solid lipid nanoparticles. |
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Thesaurus Nal: |
Chlorpyrifos; Cypermethrin. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 03893naa a2200325 a 4500
001 2144233
005 2023-03-10
008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.1016/j.vetpar.2022.109756$2DOI
100 1 $aFIGUEIREDO, A.
245 $aNanoformulations with synthetic and plant-derived compounds for cattle tick control.$h[electronic resource]
260 $c2022
300 $a9 p.
520 $aNanocarriers of acaricidal compounds improve the bioavailability, absorption, and tissue distribution of active ingredients, releasing them in a slow, targeted way and protecting them against premature degradation. Thus, this study aimed to develop formulations from solid lipid nanoparticles (SLN), or nanostructured lipid carriers (NLC) associated with cypermethrin (cip) + chlorpyrifos (chlo) and vegetable compounds (citral, menthol, or limonene). Particles were then characterised, and their efficacy was verified on R. microplus in comparison to nanoformulations without the plant-based compounds. Six different formulations were developed and characterised by dynamic light scattering (DLS) and nanoparticle tracking analysis (NTA). Formulations 1 (SLN+cyp+chlo+citral), 2 (SLN+cyp+chlo+menthol), 3 (SLN+cyp+chlo+limonene), 4 (NLC+cyp+chlo+citral), 5 (NLC+cyp+chlo+menthol) and 6 (NLC+cyp+chlo+limonene) had mean diameters from 286 to 304 nm; polydispersion from 0.16 to 0.18; zeta potential from ?15.8 to −20 mV, concentration from 3.37 ± 0.24 × 1013 to 5.44 ± 0.18 × 1013 particles/mL and encapsulation efficiency (EE) > 98.01 % for all active ingredients. All formulations were evaluated for their acaricidal potential by the larval packet test (LPT) and compared with nanoformulations without the plant-based compounds. Formulations were also compared with positive (Colosso® at 512 µg/mL) and negative controls (distilled water and nanoparticles without active ingredients). The SLN (1, 2 and 3) and NLC (4, 5 and 6) formulations, at 7 µg/mL, resulted in 90.4 % , 75.9 % , 93.8 % , 100 % , 95.1 % and 72.7 % mortality. The data demonstrated that the addition of citral, menthol or limonene in the formulations improved their acaricide action against tick larvae. Except for formulation 4, for which it was not possible to determine lethal concentrations (LC). Formulations, 1, 2, 3, 5 and 6 reached LC50 and LC90 values of 3.3 and 7.2, 5.4 and 9.2, 4.0 and 8.1, 2.3 and 5.4 as well as 5.5 and 9.4 µg/mL, respectively. It was possible to encapsulate the active ingredients and characterise the lipid carrier systems. SLN and NLC protected the active ingredients against degradation in solution and increased the overall stability. A stabile solution is necessary for synthesizing commercial acaricidal products. It is hoped that these findings may contribute to new studies focused on the use of nanocarriers in tick formulations. By reducing the amount or concentration of active ingredients within commercial products, the risk of residues presents in food of animal origin or remaining in the environment is reduced. Nanocarriers help prevent these challenges, while still maintaining effective parasitic control. Utilizing a combination of natural and synthetic products can be part of integrated management solutions and can help overcome widespread acaricide resistance in populations of cattle ticks.
650 $aChlorpyrifos
650 $aCypermethrin
653 $aCattle tick
653 $aNanostructured lipid carriers
653 $aPlant isolates
653 $aSolid lipid nanoparticles
700 1 $aANHOLETO, L. A.
700 1 $aCOLA, D. F.
700 1 $aFANTATTO, R. R.
700 1 $aSANTOS, I. B.
700 1 $aALEMÁN GAINZA, Y.
700 1 $aSOUSA, G. A.
700 1 $aPICKETT, L. J.
700 1 $aFRACETO, L. F.
700 1 $aCHAGAS, A. C. de S.
773 $tVeterinary Parasitology$gv. 309, Sep. 2022, 109756.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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Biblioteca |
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Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
URL |
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Registro Completo
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Biblioteca(s): |
Embrapa Acre; Embrapa Amapá; Embrapa Amazônia Ocidental; Embrapa Rondônia; Embrapa Roraima. |
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Data corrente: |
28/07/2023 |
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Data da última atualização: |
08/08/2023 |
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Tipo da produção científica: |
Capítulo em Livro Técnico-Científico |
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Autoria: |
WADT, L. H. de O.; SILVA, K. E. da; BAYMA, M. M. A.; BOTELHO, S. de C. C.; KAMINSKI, P. E.; GUEDES, M. C.; MEDEIROS, T. K. A. de; BALDAUF, C.; ALVES, T. C. V.; SILVA, L. de J. de S. |
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Afiliação: |
LUCIA HELENA DE OLIVEIRA WADT, CPAF-RO; KATIA EMIDIO DA SILVA, CPAA; MARCIO MUNIZ ALBANO BAYMA, CPAF-AC; SILVIA DE CARVALHO CAMPOS BOTELHO, CPAMT; PAULO EMILIO KAMINSKI, CPAF-RR; MARCELINO CARNEIRO GUEDES, CPAF-AP; TÁSSIA KARINA A. DE MEDEIROS, PREFEITURA MUNICIPAL DE NOVA MAMORÉ; CRISTINA BALDAUF, UNIVERSIDADE FEDERAL RURAL DO SEMI-ÁRIDO; THAIS CARLA VIEIRA ALVES, UNIVERSIDADE FEDERAL DO AMAZONAS; LINDOMAR DE JESUS DE SOUSA SILVA, CPAA. |
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Título: |
Coeficientes técnicos de produção e biometria. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
In: WADT, L. H. de O.; MAROCCOLO, J. F.; GUEDES, M. C.; SILVA, K. E. da (ed.). Castanha-da-amazônia: estudos sobre a espécie e sua cadeia de valor. Brasília, DF: Embrapa, 2023. |
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Páginas: |
cap. 9, p. 245-259. |
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Idioma: |
Português |
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Notas: |
V. 1: Aspectos sociais, econômicos e organizacionais. ODS 2, ODS 3, ODS 8, ODS 11, ODS 12, ODS 13, ODS 17. |
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Conteúdo: |
Este capítulo apresenta uma série de coeficientes técnicos de produção da castanha-da-amazônia, com base em estudos realizados em vários locais da Amazônia brasileira. Os resultados aqui apresentados são frutos de amostragens realizadas em diferentes regiões, mas não representam o todo da Amazônia. O objetivo do capítulo é mostrar a variabilidade existente entre e dentro de algumas regiões, tanto no tamanho dos frutos e das amêndoas da espécie, quanto no modo de produção e comercialização. Não se trata de valores absolutos e imutáveis, mas a intenção é demonstrar a elevada variabilidade que existe, trazendo valores de referências para uma possível padronização das medidas sobre a produção da castanha-da-amazônia. |
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Palavras-Chave: |
Amazônia Legal; Castanha da amazônia; Produto florestal não madeireiro (PFNM); Selo ODS 11; Selo ODS 12; Selo ODS 13; Selo ODS 17; Selo ODS 2; Selo ODS 3; Selo ODS 8. |
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Thesagro: |
Agricultura Familiar; Agricultura Sustentável; Bertholletia Excelsa; Biometria; Cadeia Produtiva; Castanha do Para; Custo de Produção; Fruto; Rendimento. |
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Thesaurus NAL: |
Amazonia; Biometry; Brazil nuts; Crop yield; Family farms; Fruits; Nontimber forest products; Production costs; Supply chain; Sustainable forestry. |
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Categoria do assunto: |
K Ciência Florestal e Produtos de Origem Vegetal |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1155411/1/cpafro-18973.pdf
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Marc: |
LEADER 02603naa a2200601 a 4500
001 2155411
005 2023-08-08
008 2023 bl uuuu u00u1 u #d
100 1 $aWADT, L. H. de O.
245 $aCoeficientes técnicos de produção e biometria.$h[electronic resource]
260 $c2023
300 $acap. 9, p. 245-259.
500 $aV. 1: Aspectos sociais, econômicos e organizacionais. ODS 2, ODS 3, ODS 8, ODS 11, ODS 12, ODS 13, ODS 17.
520 $aEste capítulo apresenta uma série de coeficientes técnicos de produção da castanha-da-amazônia, com base em estudos realizados em vários locais da Amazônia brasileira. Os resultados aqui apresentados são frutos de amostragens realizadas em diferentes regiões, mas não representam o todo da Amazônia. O objetivo do capítulo é mostrar a variabilidade existente entre e dentro de algumas regiões, tanto no tamanho dos frutos e das amêndoas da espécie, quanto no modo de produção e comercialização. Não se trata de valores absolutos e imutáveis, mas a intenção é demonstrar a elevada variabilidade que existe, trazendo valores de referências para uma possível padronização das medidas sobre a produção da castanha-da-amazônia.
650 $aAmazonia
650 $aBiometry
650 $aBrazil nuts
650 $aCrop yield
650 $aFamily farms
650 $aFruits
650 $aNontimber forest products
650 $aProduction costs
650 $aSupply chain
650 $aSustainable forestry
650 $aAgricultura Familiar
650 $aAgricultura Sustentável
650 $aBertholletia Excelsa
650 $aBiometria
650 $aCadeia Produtiva
650 $aCastanha do Para
650 $aCusto de Produção
650 $aFruto
650 $aRendimento
653 $aAmazônia Legal
653 $aCastanha da amazônia
653 $aProduto florestal não madeireiro (PFNM)
653 $aSelo ODS 11
653 $aSelo ODS 12
653 $aSelo ODS 13
653 $aSelo ODS 17
653 $aSelo ODS 2
653 $aSelo ODS 3
653 $aSelo ODS 8
700 1 $aSILVA, K. E. da
700 1 $aBAYMA, M. M. A.
700 1 $aBOTELHO, S. de C. C.
700 1 $aKAMINSKI, P. E.
700 1 $aGUEDES, M. C.
700 1 $aMEDEIROS, T. K. A. de
700 1 $aBALDAUF, C.
700 1 $aALVES, T. C. V.
700 1 $aSILVA, L. de J. de S.
773 $tIn: WADT, L. H. de O.; MAROCCOLO, J. F.; GUEDES, M. C.; SILVA, K. E. da (ed.). Castanha-da-amazônia: estudos sobre a espécie e sua cadeia de valor. Brasília, DF: Embrapa, 2023.
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Embrapa Rondônia (CPAF-RO) |
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