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| Registros recuperados : 9 | |
| 2. |  | MEDEIROS, A. M. Z.; KHAN, L. U.; SILVA, G. H. da; OSPINA, C. A.; ALVES, O. L.; CASTRO, V. L. S. S. de; MARTINEZ, D. S. T. Graphene oxide-silver nanoparticle hybrid material: an integrated nanosafety study in zebrafish embryos. Ecotoxicology and Environmental Safety, v. 209, article 111776, 2021.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 3. | | COA, F.; CLEMENTE, Z.; LOPES, J. R.; RODRIGUES NETO, L. L.; ALVES, O. L.; CASTRO, V. L. S. S. de; BARBIERI, E.; MARTINEZ, D. S. T. Green mecanochemical process for carbon nanotubes coating with humic acid: application and ecotoxicity evaluation. In: ENCONTRO ANUAL DA SOCIEDADE BRASILEIRA DE PESQUISA EM MATERIAIS, 15., 2016, Campinas. [Abstracts...] Rio de Janeiro: Sociedade Brasileira de Pesquisas em Materiais, 2016. Resumo B6SZ.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 4. | | COA, F.; CLEMENTE, Z.; LOPES, J. R.; RODRIGUES NETO, L. L.; CASTRO, V. L. S. S. de; ALVES, O. L.; BARBIERI, E.; MARTINEZ, D. S. T. Nanotubos de carbono modificados com ácido húmico: preparação, caracterização e toxicidade em embriões de zebrafish. In: CONGRESSO BRASILEIRO DE ECOTOXICOLOGIA, 14., 2016, Curitiba. Anais.... Curitiba: Sociedade Brasileira de Ecotoxicologia. p. 887-888.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 5. | | RODRIGUES, A. G.; PING, L. Y.; MARCATO, P. D.; ALVES, O. L.; SILVA, M. C. P.; RUIZ, R. C.; MELO, I. S. de; TASIC, L.; SOUZA, A. O. de. Biogenic antimicrobial silver nanoparticles produced by fungi. Applied Microbiology and Biotechnology, New York, v. 97, p. 775-782, 2013.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 6. | | DURÁN, N.; MARTINEZ, D. S. T.; JUSTO, G. Z.; LIMA, R.; CASTRO, V. L. S. S. de; UMBUZEIRO, G. A.; BARBIERI, E.; DURÁN, M.; MELO, P. S.; ALVES, O. L. Interlab study on nanotoxicology of representative graphene oxide. In: INTERNATIONAL CONFERENCE ON SAFE PRODUCTION AND USE OF NANOMATERIALS, 4, 2014, Grenoble. Book of Abstract... Grenoble: Plate-Forme Nano Sécurité, 2014.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 7. | | DURÁN, N.; MARTINEZ, D. S. T.; JUSTO, G. Z.; LIMA, R. de; CASTRO, V. L. S. S. de; UMBUZEIRO, G. de A.; BARBIERI, E.; DURÁN, M.; MELO, P. da S.; ALVES, O. L.; FÁVARO, W. J. Interlab study on nanotoxicology of representative graphene oxide. Journal of Physics, Bristol, v. 617, p. 1-9, 2015. Edition of the proceedings 4th International Conference on Safe Production and Use Nanomaterials (Nanosafe 2014) 18-20 November 2014, held a Grenoble, France.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 8. | | CÔA, F.; STRAUSS, M.; CLEMENTE, Z.; RODRIGUES NETO, L. L.; LOPES, J. R.; ALENCAR, R. S.; SOUZA FILHO, A. G.; ALVES, O. L.; CASTRO, V. L. S. S. de; BARBIERI, E.; MARTINEZ, D. S. T. Coating carbon nanotubes with humic acid using an eco-friendly mechanochemical method: Application for Cu(II) ions removal from water and aquatic ecotoxicity. Science of the Total Environment, v. 607-608, p. 1479-1486, 2017.| Biblioteca(s): Embrapa Meio Ambiente. |
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| 9. | | MEDEIROS, A. M. Z.; KHAN, L. U.; DELITE, F. S.; COSTA, C. A.; OSPINA, C. A.; ALVES, O. L.; CASTRO, V. L. S. S. de; MARTINEZ, D. S. T. Nanoecotoxicity of GO@AgNPs nanohybrid on zebrafish embryos: influence of natural organic matter and chorion membrane removal. In: INTERNATIONAL CONFERENCE ON HEALTH AND SAFETY ISSUES RELATED TO NANOMATERIALS FOR A SOCIALLY RESPONSIBLE APPROACH - NANOSAFE, 6., 2018, Grenoble. Book of Abstracts... Grenoble: 2018. Ref. A91883DM. p. 116.| Biblioteca(s): Embrapa Meio Ambiente. |
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| Registros recuperados : 9 | |
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Registro Completo
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Biblioteca(s): |
Embrapa Meio Ambiente. |
|
Data corrente: |
05/04/2021 |
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Data da última atualização: |
05/04/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
MEDEIROS, A. M. Z.; KHAN, L. U.; SILVA, G. H. da; OSPINA, C. A.; ALVES, O. L.; CASTRO, V. L. S. S. de; MARTINEZ, D. S. T. |
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Afiliação: |
ALINE MARIA ZIGIOTTO DE MEDEIROS, CNPEM; LATIF ULLAH KHAN, CNPEM; GABRIELA HELENA DA SILVA, CNPEM; CARLOS ALBERTO OSPINA, CNPEM; OSWALDO LUIZ ALVES, IQ-UNICAMP; VERA LUCIA SCHERHOLZ S DE CASTRO, CNPMA; DIEGO STÉFANI TEODORO MARTINEZ, CNPEM. |
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Título: |
Graphene oxide-silver nanoparticle hybrid material: an integrated nanosafety study in zebrafish embryos. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Ecotoxicology and Environmental Safety, v. 209, article 111776, 2021. |
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ISSN: |
0147-6513 |
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DOI: |
https://doi.org/10.1016/j.ecoenv.2020.111776 |
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Idioma: |
Inglês |
|
Conteúdo: |
Abstract: This work reports an integrated nanosafety study including the synthesis and characterization of the graphene oxide-silver nanoparticle hybrid material (GO-AgNPs) and its nano-ecotoxicity evaluation in the zebrafish embryo model. The influences of natural organic matter (NOM) and a chorion embryo membrane were considered in this study, looking towards more environmentally realistic scenarios and standardized nanotoxicity testing. The nanohybrid was successfully synthesized using the NaBH4 aqueous method, and AgNPs (~ 5.8 nm) were evenly distributed over the GO surface. GO-AgNPs showed a dose-response acute toxicity: the LC50 was 1.5 mg L-1 for chorionated embryos. The removal of chorion, however, increased this toxic effect by 50%. Furthermore, the presence of NOM mitigated mortality, and LC50 for GO-AgNPs changed respectively from 2.3 to 1.2 mg L-1 for chorionated and de-chorionated embryos. Raman spectroscopy confirmed the ingestion of GO by embryos; but without displaying acute toxicity up to 100 mg L-1, indicating that the silver drove toxicity down. Additionally, it was observed that silver nanoparticle dissolution has a minimal effect on these observed toxicity results. Finally, understanding the influence of chorion membranes and NOM is a critical step towards the standardization of testing for zebrafish embryo toxicity in safety assessments and regulatory issues. |
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Palavras-Chave: |
Alternative methods; Grafeno; Nanoecotoxicology; Nanohybrids; Nanomateriais; Nanotoxicity. |
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Thesagro: |
Composto de Carbono; Peixe de Água Doce; Toxidez. |
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Thesaurus NAL: |
chorion; Danio rerio; Ecotoxicology; Graphene oxide; Nanomaterials. |
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Categoria do assunto: |
P Recursos Naturais, Ciências Ambientais e da Terra |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/222338/1/Castro-Graphene-oxide-2021.pdf
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Marc: |
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260 $c2021
520 $aAbstract: This work reports an integrated nanosafety study including the synthesis and characterization of the graphene oxide-silver nanoparticle hybrid material (GO-AgNPs) and its nano-ecotoxicity evaluation in the zebrafish embryo model. The influences of natural organic matter (NOM) and a chorion embryo membrane were considered in this study, looking towards more environmentally realistic scenarios and standardized nanotoxicity testing. The nanohybrid was successfully synthesized using the NaBH4 aqueous method, and AgNPs (~ 5.8 nm) were evenly distributed over the GO surface. GO-AgNPs showed a dose-response acute toxicity: the LC50 was 1.5 mg L-1 for chorionated embryos. The removal of chorion, however, increased this toxic effect by 50%. Furthermore, the presence of NOM mitigated mortality, and LC50 for GO-AgNPs changed respectively from 2.3 to 1.2 mg L-1 for chorionated and de-chorionated embryos. Raman spectroscopy confirmed the ingestion of GO by embryos; but without displaying acute toxicity up to 100 mg L-1, indicating that the silver drove toxicity down. Additionally, it was observed that silver nanoparticle dissolution has a minimal effect on these observed toxicity results. Finally, understanding the influence of chorion membranes and NOM is a critical step towards the standardization of testing for zebrafish embryo toxicity in safety assessments and regulatory issues.
650 $achorion
650 $aDanio rerio
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