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Registro Completo
Biblioteca(s): |
Embrapa Agroenergia. |
Data corrente: |
08/06/2022 |
Data da última atualização: |
08/06/2022 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Circulação/Nível: |
A - 2 |
Autoria: |
TRINCHEZ, D.; CARNEIRO, C. V. G. C.; BRAGA, M.; ALMEIDA, J. R. M. de. |
Afiliação: |
DÉBORA TRICHEZ; CLARA VIDA G. C. CARNEIRO, Bolsista, UnB - Embrapa Agroenergia; MELISSA BRAGA, CNPAE; JOAO RICARDO MOREIRA DE ALMEIDA, CNPAE. |
Título: |
Recent progress in the microbial production of xylonic acid. |
Ano de publicação: |
2022 |
Fonte/Imprenta: |
World Journal of Microbiology and Biotechnology, v.38, n. 127, 2022. |
DOI: |
https://doi.org/10.1007/s11274-022-03313-5 |
Idioma: |
Inglês |
Conteúdo: |
Interest in the production of renewable chemicals from biomass has increased in the past years. Among these chemicals, carboxylic acids represent a significant part of the most desirable bio-based products. Xylonic acid is a five-carbon sugar-acid obtained from xylose oxidation that can be used in several industrial applications, including food, pharmaceutical, and con-struction industries. So far, the production of xylonic acid has not yet been available at an industrial scale; however, several microbial bio-based production processes are under development. This review summarizes the recent advances in pathway characterization, genetic engineering, and fermentative strategies to improve xylonic acid production by microorganisms from xylose or lignocellulosic hydrolysates. In addition, the strengths of the available microbial strains and processes and the major requirements for achieving biotechnological production of xylonic acid at a commercial scale are discussed. Efficient native and engineered microbial strains have been reported. Xylonic acid titers as high as 586 and 171 g L −1 were obtained from bacterial and yeast strains, respectively, in a laboratory medium. Furthermore, relevant academic and industrial players associated with xylonic acid production will be presented. |
Palavras-Chave: |
Bio-based products; Biomass hydrolysate; Microbial carboxylic acid production; Xylonic acid. |
Categoria do assunto: |
-- |
Marc: |
LEADER 01998naa a2200217 a 4500 001 2143846 005 2022-06-08 008 2022 bl uuuu u00u1 u #d 024 7 $ahttps://doi.org/10.1007/s11274-022-03313-5$2DOI 100 1 $aTRINCHEZ, D. 245 $aRecent progress in the microbial production of xylonic acid.$h[electronic resource] 260 $c2022 520 $aInterest in the production of renewable chemicals from biomass has increased in the past years. Among these chemicals, carboxylic acids represent a significant part of the most desirable bio-based products. Xylonic acid is a five-carbon sugar-acid obtained from xylose oxidation that can be used in several industrial applications, including food, pharmaceutical, and con-struction industries. So far, the production of xylonic acid has not yet been available at an industrial scale; however, several microbial bio-based production processes are under development. This review summarizes the recent advances in pathway characterization, genetic engineering, and fermentative strategies to improve xylonic acid production by microorganisms from xylose or lignocellulosic hydrolysates. In addition, the strengths of the available microbial strains and processes and the major requirements for achieving biotechnological production of xylonic acid at a commercial scale are discussed. Efficient native and engineered microbial strains have been reported. Xylonic acid titers as high as 586 and 171 g L −1 were obtained from bacterial and yeast strains, respectively, in a laboratory medium. Furthermore, relevant academic and industrial players associated with xylonic acid production will be presented. 653 $aBio-based products 653 $aBiomass hydrolysate 653 $aMicrobial carboxylic acid production 653 $aXylonic acid 700 1 $aCARNEIRO, C. V. G. C. 700 1 $aBRAGA, M. 700 1 $aALMEIDA, J. R. M. de 773 $tWorld Journal of Microbiology and Biotechnology$gv.38, n. 127, 2022.
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