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 | Acesso ao texto completo restrito à biblioteca da Embrapa Suínos e Aves. Para informações adicionais entre em contato com cnpsa.biblioteca@embrapa.br. |
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Registro Completo |
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
04/11/2020 |
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Data da última atualização: |
04/11/2020 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ESPÍNDOLA, J. P.; BALBINOTT, N.; GRESSLER, L. T.; MACHADO, G.; KLEIN, C. S.; REBELATTO, R.; MARTÍN, C. B. G.; KREUTZ, L. C.; SCHRYVERS, A. B.; FRANDOLOSO, R. |
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Afiliação: |
JÚLIA PIRES ESPÍNDOLA, UPF; NATÁLIA BALBINOTT, UPF; LETÍCIA TREVISAN GRESSLER, UPF; GUSTAVO MACHADO, North Carolina State University; CATIA SILENE KLEIN, CNPSA; RAQUEL REBELATTO, CNPSA; CÉSAR BERNARDO GUTIÉRREZ MARTÍN, University of León; LUIZ CARLOS KREUTZ, UPF; ANTHONY BERNARD SCHRYVERS, University of Calgary; RAFAEL FRANDOLOSO, UPF. |
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Título: |
Molecular serotyping of clinical strains of Haemophilus (Glaesserella) parasuis brings new insights regarding Glassers disease outbreaks in Brazil. |
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Ano de publicação: |
2019 |
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Fonte/Imprenta: |
PeerJ, v. 7, n. e6817, 2019. |
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DOI: |
http://doi.org/10.7717/peerj.6817 |
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Idioma: |
Inglês |
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Conteúdo: |
Abstract: Glässer's disease (GD) is an important infectious disease of swine caused by Haemophilus (Glaesserella) parasuis. Vaccination with inactivated whole cell vaccines is the major approach for prevention of H. parasuis infection worldwide, but the immunity induced is predominantly against the specific polysaccharide capsule. As a consequence, the available vaccines may not induce adequate protection against the field strains, when the capsules present in the vaccine strains are different from those in strains isolated from the farms. Therefore, it is crucial to map H. parasuis serovars associated with regional outbreaks so that appropriate bacterin vaccines can be developed and distributed for prevention of infection. In this study, 459 H. parasuis field strains isolated from different Glässer's disease outbreaks that occurred in 10 different Brazilian States were analyzed for serotype using PCR-based approaches. Surprisingly, non-typeable (NT) strains were the second most prevalent group of field strains and along with serovars 4, 5 and 1 comprised more than 70% of the isolates. A PCRbased approach designed to amplify the entire polysaccharide capsule locus revealed 9 different band patterns in the NT strains, and 75% of the NT strains belonged to three clusters, suggesting that a number of new serovars are responsible for a substantial proportion of disease. These results indicate that commercially available vaccines in Brazil do not cover the most prevalent H. parasuis serovars associated with GD. Disease mapping, Haemophilus parasuis, Typification, Serovars, Vaccines, Brazil Microbiology, Veterinary Medicine MenosAbstract: Glässer's disease (GD) is an important infectious disease of swine caused by Haemophilus (Glaesserella) parasuis. Vaccination with inactivated whole cell vaccines is the major approach for prevention of H. parasuis infection worldwide, but the immunity induced is predominantly against the specific polysaccharide capsule. As a consequence, the available vaccines may not induce adequate protection against the field strains, when the capsules present in the vaccine strains are different from those in strains isolated from the farms. Therefore, it is crucial to map H. parasuis serovars associated with regional outbreaks so that appropriate bacterin vaccines can be developed and distributed for prevention of infection. In this study, 459 H. parasuis field strains isolated from different Glässer's disease outbreaks that occurred in 10 different Brazilian States were analyzed for serotype using PCR-based approaches. Surprisingly, non-typeable (NT) strains were the second most prevalent group of field strains and along with serovars 4, 5 and 1 comprised more than 70% of the isolates. A PCRbased approach designed to amplify the entire polysaccharide capsule locus revealed 9 different band patterns in the NT strains, and 75% of the NT strains belonged to three clusters, suggesting that a number of new serovars are responsible for a substantial proportion of disease. These results indicate that commercially available vaccines in Brazil do not cover the most prevalent H. paras... Mostrar Tudo |
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Palavras-Chave: |
Brasil; Disease mapping; Serovares; Serovars; Tipificação; Typification. |
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Thesagro: |
Microbiologia; Vacina; Veterinária. |
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Thesaurus Nal: |
Brazil; Haemophilus parasuis; Microbiology; Vaccines; Veterinary medicine. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 02802naa a2200409 a 4500
001 2126299
005 2020-11-04
008 2019 bl uuuu u00u1 u #d
024 7 $ahttp://doi.org/10.7717/peerj.6817$2DOI
100 1 $aESPÍNDOLA, J. P.
245 $aMolecular serotyping of clinical strains of Haemophilus (Glaesserella) parasuis brings new insights regarding Glassers disease outbreaks in Brazil.$h[electronic resource]
260 $c2019
520 $aAbstract: Glässer's disease (GD) is an important infectious disease of swine caused by Haemophilus (Glaesserella) parasuis. Vaccination with inactivated whole cell vaccines is the major approach for prevention of H. parasuis infection worldwide, but the immunity induced is predominantly against the specific polysaccharide capsule. As a consequence, the available vaccines may not induce adequate protection against the field strains, when the capsules present in the vaccine strains are different from those in strains isolated from the farms. Therefore, it is crucial to map H. parasuis serovars associated with regional outbreaks so that appropriate bacterin vaccines can be developed and distributed for prevention of infection. In this study, 459 H. parasuis field strains isolated from different Glässer's disease outbreaks that occurred in 10 different Brazilian States were analyzed for serotype using PCR-based approaches. Surprisingly, non-typeable (NT) strains were the second most prevalent group of field strains and along with serovars 4, 5 and 1 comprised more than 70% of the isolates. A PCRbased approach designed to amplify the entire polysaccharide capsule locus revealed 9 different band patterns in the NT strains, and 75% of the NT strains belonged to three clusters, suggesting that a number of new serovars are responsible for a substantial proportion of disease. These results indicate that commercially available vaccines in Brazil do not cover the most prevalent H. parasuis serovars associated with GD. Disease mapping, Haemophilus parasuis, Typification, Serovars, Vaccines, Brazil Microbiology, Veterinary Medicine
650 $aBrazil
650 $aHaemophilus parasuis
650 $aMicrobiology
650 $aVaccines
650 $aVeterinary medicine
650 $aMicrobiologia
650 $aVacina
650 $aVeterinária
653 $aBrasil
653 $aDisease mapping
653 $aSerovares
653 $aSerovars
653 $aTipificação
653 $aTypification
700 1 $aBALBINOTT, N.
700 1 $aGRESSLER, L. T.
700 1 $aMACHADO, G.
700 1 $aKLEIN, C. S.
700 1 $aREBELATTO, R.
700 1 $aMARTÍN, C. B. G.
700 1 $aKREUTZ, L. C.
700 1 $aSCHRYVERS, A. B.
700 1 $aFRANDOLOSO, R.
773 $tPeerJ$gv. 7, n. e6817, 2019.
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Registro original: |
Embrapa Suínos e Aves (CNPSA) |
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Tipo/Formato |
Classificação |
Cutter |
Registro |
Volume |
Status |
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Registro Completo
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Biblioteca(s): |
Embrapa Unidades Centrais. |
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Data corrente: |
10/02/2016 |
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Data da última atualização: |
10/02/2016 |
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Autoria: |
AVILA, A. F. D.; RODRIGUES, G. S.; VEDOVOTO, G. L.; PENTEADO FILHO, R. de C.; FONSECA JUNIOR, W. C. da. |
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Afiliação: |
ANTONIO FLAVIO DIAS AVILA, SGE; GERALDO STACHETTI RODRIGUES, CNPMA; GRACIELA LUZIA VEDOVOTO, SGE; ROBERTO DE CAMARGO PENTEADO FILHO, SGE; WILSON CORREA DA FONSECA JUNIOR, SECOM. |
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Título: |
Embrapa experience on the impact assessment of agricultural R&D: 15 years using a multidimensional approach. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
In: IMPAR CONFERENCE, 2015, Paris. Impacts of agricultural research: towards an approach of societal values: [proceedings...]. Paris: INRA, 2015. 25 p. |
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Idioma: |
Português |
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Conteúdo: |
After decades doing sporadic studies on impact assessment and using diversified approaches focused on economic effects, Embrapa is now completing 15 years of an institutionalized system based in a common multidimensional approach measuring economic, social, environmental, political and scientific impacts of its main technologies. Since 2001, Embrapa is monitoring and evaluating more than one hundred technologies and around 200 cultivars originated from its 42 research centers. An impact assessment team, located at the Embrapa Headquarters, by the Secretariat for Management and Institutional Development (SGI), coordinates the system. This central unit is responsible for the analysis and consolidation of the results, and to give feedback to local teams, as to continually improve their analysis. This process is completed with an official and annual publication reporting on the multidimensional impacts, named Embrapa?s Social Report (http://bs.sede.embrapa.br/). The impact studies include the estimation of economic surpluses generated by Embrapa technologies based on field data collected through a private national survey (for cultivars) and by local/regional research teams for surveys regarding the other technologies. Internal rates of return are estimated using benefits and costs data series. To evaluate social and environmental impacts research teams in each center interviews a sample of technology adopters to measure their perception on the innovations? impacts, comparatively to the former technologies or practices replaced. A reference multicriteria method, named Ambitec-Agro, is applied to estimate multiple indices evaluating positive and negative impacts in a set of socioenvironmental indicators. More recently, new impacts are being measured including the contribution of Embrapa to the formulation of public policies and its scientific impact to the advancement of science, measured by the publication of articles on refereed journals, citations and establishment of R&D networks. It is important to note that the development of econometric and other more sophisticated impact assessment analyses continue to be developed at Embrapa?s consultants have developed aggregate impact studies, or specific R&D assessments for especial research areas, such as genetic breeding. This continuous impact system has been extremely important to Embrapa?s institutional sustainability. Certainly, the strong support received by the corporation from Brazilian society is due in large part to this institutionalized consultants have developed aggregate impact studies, or specific R&D assessments for especial research areas, such as genetic breeding. This continuous impact system has been extremely important to Embrapa?s institutional sustainability. Certainly, the strong support received by the corporation from Brazilian society is due in large part to this institutionalized system that shows not only results (outputs), but also their use and application impacts. MenosAfter decades doing sporadic studies on impact assessment and using diversified approaches focused on economic effects, Embrapa is now completing 15 years of an institutionalized system based in a common multidimensional approach measuring economic, social, environmental, political and scientific impacts of its main technologies. Since 2001, Embrapa is monitoring and evaluating more than one hundred technologies and around 200 cultivars originated from its 42 research centers. An impact assessment team, located at the Embrapa Headquarters, by the Secretariat for Management and Institutional Development (SGI), coordinates the system. This central unit is responsible for the analysis and consolidation of the results, and to give feedback to local teams, as to continually improve their analysis. This process is completed with an official and annual publication reporting on the multidimensional impacts, named Embrapa?s Social Report (http://bs.sede.embrapa.br/). The impact studies include the estimation of economic surpluses generated by Embrapa technologies based on field data collected through a private national survey (for cultivars) and by local/regional research teams for surveys regarding the other technologies. Internal rates of return are estimated using benefits and costs data series. To evaluate social and environmental impacts research teams in each center interviews a sample of technology adopters to measure their perception on the innovations? impacts, comparatively... Mostrar Tudo |
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Palavras-Chave: |
Avaliação de impacto; Impact assessment; Multidimensional approach; Public research centers. |
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Thesagro: |
Impacto ambiental; Impacto econômico; Impacto social; Pesquisa agrícola. |
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Thesaurus NAL: |
agricultural research; economic impact; environmental impact; social impact. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/138651/1/Embrapa-Experience-on-the-impact.pdf
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Marc: |
LEADER 04056nam a2200301 a 4500
001 2036444
005 2016-02-10
008 2015 bl uuuu u00u1 u #d
100 1 $aAVILA, A. F. D.
245 $aEmbrapa experience on the impact assessment of agricultural R&D$b15 years using a multidimensional approach.$h[electronic resource]
260 $aIn: IMPAR CONFERENCE, 2015, Paris. Impacts of agricultural research: towards an approach of societal values: [proceedings...]. Paris: INRA, 2015. 25 p.$c2015
520 $aAfter decades doing sporadic studies on impact assessment and using diversified approaches focused on economic effects, Embrapa is now completing 15 years of an institutionalized system based in a common multidimensional approach measuring economic, social, environmental, political and scientific impacts of its main technologies. Since 2001, Embrapa is monitoring and evaluating more than one hundred technologies and around 200 cultivars originated from its 42 research centers. An impact assessment team, located at the Embrapa Headquarters, by the Secretariat for Management and Institutional Development (SGI), coordinates the system. This central unit is responsible for the analysis and consolidation of the results, and to give feedback to local teams, as to continually improve their analysis. This process is completed with an official and annual publication reporting on the multidimensional impacts, named Embrapa?s Social Report (http://bs.sede.embrapa.br/). The impact studies include the estimation of economic surpluses generated by Embrapa technologies based on field data collected through a private national survey (for cultivars) and by local/regional research teams for surveys regarding the other technologies. Internal rates of return are estimated using benefits and costs data series. To evaluate social and environmental impacts research teams in each center interviews a sample of technology adopters to measure their perception on the innovations? impacts, comparatively to the former technologies or practices replaced. A reference multicriteria method, named Ambitec-Agro, is applied to estimate multiple indices evaluating positive and negative impacts in a set of socioenvironmental indicators. More recently, new impacts are being measured including the contribution of Embrapa to the formulation of public policies and its scientific impact to the advancement of science, measured by the publication of articles on refereed journals, citations and establishment of R&D networks. It is important to note that the development of econometric and other more sophisticated impact assessment analyses continue to be developed at Embrapa?s consultants have developed aggregate impact studies, or specific R&D assessments for especial research areas, such as genetic breeding. This continuous impact system has been extremely important to Embrapa?s institutional sustainability. Certainly, the strong support received by the corporation from Brazilian society is due in large part to this institutionalized consultants have developed aggregate impact studies, or specific R&D assessments for especial research areas, such as genetic breeding. This continuous impact system has been extremely important to Embrapa?s institutional sustainability. Certainly, the strong support received by the corporation from Brazilian society is due in large part to this institutionalized system that shows not only results (outputs), but also their use and application impacts.
650 $aagricultural research
650 $aeconomic impact
650 $aenvironmental impact
650 $asocial impact
650 $aImpacto ambiental
650 $aImpacto econômico
650 $aImpacto social
650 $aPesquisa agrícola
653 $aAvaliação de impacto
653 $aImpact assessment
653 $aMultidimensional approach
653 $aPublic research centers
700 1 $aRODRIGUES, G. S.
700 1 $aVEDOVOTO, G. L.
700 1 $aPENTEADO FILHO, R. de C.
700 1 $aFONSECA JUNIOR, W. C. da
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Embrapa Unidades Centrais (AI-SEDE) |
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