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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
07/07/2010 |
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Data da última atualização: |
23/09/2019 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
ORIÁ, R. B.; PATRICK, P. D.; ORIÁ, M. O. B.; LORNTZ, B.; THOMPSON, M. R.; AZEVEDO, O. G. R.; LOBO, R. N. B.; PINKERTON, R. F.; GUERRANT, R. L.; LIMA, A. A. M. |
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Afiliação: |
Departamento de Morfologia e Instituto de Biomedicina do Semi-árido Brasileiro (IBISAB), Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE; Kluge Children’s Rehabilitation and Research Center, University of Virginia, Charlottesville, VA, USA; Departamento de Enfermagem, Universidade Federal do Ceará, Fortaleza, CE; Instituto de Biomedicina do Semi-árido Brasileiro (IBISAB), Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE; Center for Global Health, School of Medicine; Instituto de Biomedicina do Semi-árido Brasileiro (IBISAB), Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE; RAIMUNDO NONATO BRAGA LOBO, CNPC; Center for Global Health, School of Medicine; Center for Global Health, School of Medicine e Instituto de Biomedicina do Semi-árido Brasileiro (IBISAB), Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE; Center for Global Health, School of Medicine e Instituto de Biomedicina do Semi-árido Brasileiro (IBISAB), Faculdade de Medicina, Universidade Federal do Ceará, Fortaleza, CE. |
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Título: |
ApoE polymorphisms and diarrheal outcomes in Brazilian shanty town children. |
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Ano de publicação: |
2010 |
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Fonte/Imprenta: |
Brazilian Journal of Medical and Biological Research, v. 43, n. 3, p. 249-256, Mar. 2010. |
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Idioma: |
Inglês |
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Conteúdo: |
A series of studies have shown that the heavy burdens of diarrheal diseases in the first 2 formative years of life in children living in urban shanty towns have negative effects on physical and cognitive development lasting into later childhood. We have shown that APOE4 is relatively common in shanty town children living in Brazil (13.4%) and suggest that APOE4 has a protective role in cognitive development as well as weight-for-height in children with heavy burdens of diarrhea in early childhood (64/123; 52%), despite being a marker for cognitive decline with Alzheimer?s and cardiovascular diseases later in life. APOE2 frequency was higher among children with heaviest diarrhea burdens during the first 2 years of life, as detected by PCR using the restriction fragment length polymorphism method, raising the possibility that ApoE-cholesterol balance might be critical for growth and cognitive development under the stress of heavy diarrhea burdens and when an enriched fat diet is insufficient. These findings provide a potential explanation for the survival advantage in evolution of genes, which might raise cholesterol levels during heavy stress of diarrhea burdens and malnutrition early in life. |
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Thesaurus Nal: |
Apolipoprotein E; Children; Diarrhea; Malnutrition. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/28863/1/API-ApoE-polymorphisms-and-diarrheal-outcomes-in-Brazilian-shanty-town-children.pdf
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Marc: |
LEADER 02017naa a2200277 a 4500
001 1857019
005 2019-09-23
008 2010 bl uuuu u00u1 u #d
100 1 $aORIÁ, R. B.
245 $aApoE polymorphisms and diarrheal outcomes in Brazilian shanty town children.$h[electronic resource]
260 $c2010
520 $aA series of studies have shown that the heavy burdens of diarrheal diseases in the first 2 formative years of life in children living in urban shanty towns have negative effects on physical and cognitive development lasting into later childhood. We have shown that APOE4 is relatively common in shanty town children living in Brazil (13.4%) and suggest that APOE4 has a protective role in cognitive development as well as weight-for-height in children with heavy burdens of diarrhea in early childhood (64/123; 52%), despite being a marker for cognitive decline with Alzheimer?s and cardiovascular diseases later in life. APOE2 frequency was higher among children with heaviest diarrhea burdens during the first 2 years of life, as detected by PCR using the restriction fragment length polymorphism method, raising the possibility that ApoE-cholesterol balance might be critical for growth and cognitive development under the stress of heavy diarrhea burdens and when an enriched fat diet is insufficient. These findings provide a potential explanation for the survival advantage in evolution of genes, which might raise cholesterol levels during heavy stress of diarrhea burdens and malnutrition early in life.
650 $aApolipoprotein E
650 $aChildren
650 $aDiarrhea
650 $aMalnutrition
700 1 $aPATRICK, P. D.
700 1 $aORIÁ, M. O. B.
700 1 $aLORNTZ, B.
700 1 $aTHOMPSON, M. R.
700 1 $aAZEVEDO, O. G. R.
700 1 $aLOBO, R. N. B.
700 1 $aPINKERTON, R. F.
700 1 $aGUERRANT, R. L.
700 1 $aLIMA, A. A. M.
773 $tBrazilian Journal of Medical and Biological Research$gv. 43, n. 3, p. 249-256, Mar. 2010.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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 | Acesso ao texto completo restrito à biblioteca da Embrapa Mandioca e Fruticultura. Para informações adicionais entre em contato com cnpmf.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Mandioca e Fruticultura. |
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Data corrente: |
30/11/2022 |
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Data da última atualização: |
30/11/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
B - 5 |
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Autoria: |
OZKAYA, D. E.; SOUZA, F. V. D.; KAYA, E. |
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Afiliação: |
DAMLA EKIN OZKAYA, MUGLA SITKI KOCMAN UNIVERSITY; FERNANDA VIDIGAL DUARTE SOUZA, CNPMF; ERGUN KAYA, MUGLA SITKI KOCMAN UNIVERSITY. |
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Título: |
Evaluation of critical points for effective cryopreservation of four different citrus spp. germplasm. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Horticulturae, v.8, p.995, 2022. |
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ISSN: |
2311-7524 |
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DOI: |
https://doi.org/10.3390/horticulturae8110995. |
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Idioma: |
Inglês |
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Conteúdo: |
The different pre- and post-treatments are critical in cryopreservation procedures and affect the shoot tip regrowth after freezing. In the present study, the long-term storage of four citrus cultivars [Bodrum Mandarin (Citrus deliciosa Ten.); Klin Mandarin (Citrus nobilis Lauriro); White grapefruit and Red grapefruit (Citrus paradisi L.)] were carried out by droplet vitrification methods, and the critical points for effective cryopreservation of these species were determined. In this study, we investigated the effect of explant size, cold hardening treatments, sucrose concentrations, and media combinations on shoot regrowth after cryopreservation. The highest shoot tip regrowth, ranging from 13.3 to 33.3%, was achieved when they were obtained from 0.3 to 0.7 mm explants excised from cold hardened seedlings at 4 °C for three days that were then precultured in a medium containing 0.25 M of sucrose and treated with PVS2 at 0 °C for 45 min. In addition, it has been determined that a regeneration medium containing boric acid (H3BO3) or ferric ethylenediaminetetraacetate (FeEDDHA) increased the regeneration up to 33.3% after cryopreservation. |
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Thesagro: |
Banco de Germoplasma; Criopreservação. |
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Categoria do assunto: |
-- |
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Marc: |
LEADER 01758naa a2200193 a 4500
001 2149035
005 2022-11-30
008 2022 bl uuuu u00u1 u #d
022 $a2311-7524
024 7 $ahttps://doi.org/10.3390/horticulturae8110995.$2DOI
100 1 $aOZKAYA, D. E.
245 $aEvaluation of critical points for effective cryopreservation of four different citrus spp. germplasm.$h[electronic resource]
260 $c2022
520 $aThe different pre- and post-treatments are critical in cryopreservation procedures and affect the shoot tip regrowth after freezing. In the present study, the long-term storage of four citrus cultivars [Bodrum Mandarin (Citrus deliciosa Ten.); Klin Mandarin (Citrus nobilis Lauriro); White grapefruit and Red grapefruit (Citrus paradisi L.)] were carried out by droplet vitrification methods, and the critical points for effective cryopreservation of these species were determined. In this study, we investigated the effect of explant size, cold hardening treatments, sucrose concentrations, and media combinations on shoot regrowth after cryopreservation. The highest shoot tip regrowth, ranging from 13.3 to 33.3%, was achieved when they were obtained from 0.3 to 0.7 mm explants excised from cold hardened seedlings at 4 °C for three days that were then precultured in a medium containing 0.25 M of sucrose and treated with PVS2 at 0 °C for 45 min. In addition, it has been determined that a regeneration medium containing boric acid (H3BO3) or ferric ethylenediaminetetraacetate (FeEDDHA) increased the regeneration up to 33.3% after cryopreservation.
650 $aBanco de Germoplasma
650 $aCriopreservação
700 1 $aSOUZA, F. V. D.
700 1 $aKAYA, E.
773 $tHorticulturae$gv.8, p.995, 2022.
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Embrapa Mandioca e Fruticultura (CNPMF) |
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