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Registro Completo |
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Biblioteca(s): |
Embrapa Amazônia Oriental. |
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Data corrente: |
13/03/2014 |
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Data da última atualização: |
19/10/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
COSTA, F.; PORTER, F. H.; RODRIGUES, G.; FARIAS, H.; FARIA, M. T. de; WUNDER, E. A.; OSIKOWICZ, L. M.; KOSOY, M. Y.; REIS, M. G.; KO, A. I.; CHILDS, J. E. |
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Afiliação: |
FREDERICO COSTA, Fundação Oswaldo Cruz; Fleur Helena Porter, Yale University; GORETE RODRIGUES, Secretaria Municipal de Saúde de Salvador; HELENA FARIAS, Secretaria Municipal de Saúde de Salvador; MARCOS TUCUNDUVA DE FARIA, CPATU; Elsio A. Wunder, Yale University; Lynn M. Osikowicz, DVBID, Centers for Disease Control and Prevention; Michael Y. Kosoy, DVBID, Centers for Disease Control and Prevention; Mitermayer Galvão Reis, Fundação Oswaldo Cruz; Albert I. Ko, Yale University; James E. Childs, Yale University School of Medicine. |
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Título: |
Infections by Leptospira interrogans, Seoul Virus, and Bartonella spp. among Norway rats (Rattus norvegicus) from the urban slum environment in Brazil. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
Vector-Borne and Zoonotic Diseases, v. 14, n. 1, p. 33-40, Jan. 2014. |
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DOI: |
10.1089/vbz.2013.1378 |
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Idioma: |
Inglês |
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Conteúdo: |
Norway rats (Rattus norvegicus) are reservoir hosts for zoonotic pathogens that cause significant morbidity and mortality in humans. Studies evaluating the prevalence of zoonotic pathogens in tropical Norway rat populations are rare, and data on co-infection with multiple pathogens are nonexistent. Herein, we describe the prevalence of leptospiral carriage, Seoul virus (SEOV), and Bartonella spp. infection independently, in addition to the rates of co-infection among urban, slum-dwelling Norway rats in Salvador, Brazil, trapped during the rainy season from June to August of 2010. These data were complemented with previously unpublished Leptospira and SEOV prevalence information collected in 1998. Immunofluorescence staining of kidney impressions was used to identify Leptospira interrogans in 2010, whereas isolation was used in 1998, and western blotting was used to detect SEOV antibodies in 2010, whereas enzyme-linked immunosorbent assay (ELISA) was used in 1998: in 2010, Bartonella spp. were isolated from a subsample of rats. The most common pathogen in both years was Leptospira spp. (83%, n=142 in 1998, 63%, n=84 in 2010). SEOV was detected in 18% of individuals in both 1998 and 2010 (n=78 in 1998; n=73 in 2010), and two species of Bartonella were isolated from 5 of 26 rats (19%) tested in 2010. The prevalence of all agents increased significantly with rat mass/age. Acquisition of Leptospira spp. occurred at a younger mass/age than SEOV and Bartonella spp. infection, suggesting differences in the transmission dynamics of these pathogens. These data indicate that Norway rats in Salvador serve as reservoir hosts for all three of these zoonotic pathogens and that the high prevalence of leptospiral carriage in Salvador rats poses a high degree of risk to human health. MenosNorway rats (Rattus norvegicus) are reservoir hosts for zoonotic pathogens that cause significant morbidity and mortality in humans. Studies evaluating the prevalence of zoonotic pathogens in tropical Norway rat populations are rare, and data on co-infection with multiple pathogens are nonexistent. Herein, we describe the prevalence of leptospiral carriage, Seoul virus (SEOV), and Bartonella spp. infection independently, in addition to the rates of co-infection among urban, slum-dwelling Norway rats in Salvador, Brazil, trapped during the rainy season from June to August of 2010. These data were complemented with previously unpublished Leptospira and SEOV prevalence information collected in 1998. Immunofluorescence staining of kidney impressions was used to identify Leptospira interrogans in 2010, whereas isolation was used in 1998, and western blotting was used to detect SEOV antibodies in 2010, whereas enzyme-linked immunosorbent assay (ELISA) was used in 1998: in 2010, Bartonella spp. were isolated from a subsample of rats. The most common pathogen in both years was Leptospira spp. (83%, n=142 in 1998, 63%, n=84 in 2010). SEOV was detected in 18% of individuals in both 1998 and 2010 (n=78 in 1998; n=73 in 2010), and two species of Bartonella were isolated from 5 of 26 rats (19%) tested in 2010. The prevalence of all agents increased significantly with rat mass/age. Acquisition of Leptospira spp. occurred at a younger mass/age than SEOV and Bartonella spp. infection, sugge... Mostrar Tudo |
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Palavras-Chave: |
Ratos da Noruega. |
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Thesagro: |
Infecção. |
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Categoria do assunto: |
H Saúde e Patologia |
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Marc: |
LEADER 02657naa a2200277 a 4500
001 1982276
005 2022-10-19
008 2014 bl uuuu u00u1 u #d
024 7 $a10.1089/vbz.2013.1378$2DOI
100 1 $aCOSTA, F.
245 $aInfections by Leptospira interrogans, Seoul Virus, and Bartonella spp. among Norway rats (Rattus norvegicus) from the urban slum environment in Brazil.$h[electronic resource]
260 $c2014
520 $aNorway rats (Rattus norvegicus) are reservoir hosts for zoonotic pathogens that cause significant morbidity and mortality in humans. Studies evaluating the prevalence of zoonotic pathogens in tropical Norway rat populations are rare, and data on co-infection with multiple pathogens are nonexistent. Herein, we describe the prevalence of leptospiral carriage, Seoul virus (SEOV), and Bartonella spp. infection independently, in addition to the rates of co-infection among urban, slum-dwelling Norway rats in Salvador, Brazil, trapped during the rainy season from June to August of 2010. These data were complemented with previously unpublished Leptospira and SEOV prevalence information collected in 1998. Immunofluorescence staining of kidney impressions was used to identify Leptospira interrogans in 2010, whereas isolation was used in 1998, and western blotting was used to detect SEOV antibodies in 2010, whereas enzyme-linked immunosorbent assay (ELISA) was used in 1998: in 2010, Bartonella spp. were isolated from a subsample of rats. The most common pathogen in both years was Leptospira spp. (83%, n=142 in 1998, 63%, n=84 in 2010). SEOV was detected in 18% of individuals in both 1998 and 2010 (n=78 in 1998; n=73 in 2010), and two species of Bartonella were isolated from 5 of 26 rats (19%) tested in 2010. The prevalence of all agents increased significantly with rat mass/age. Acquisition of Leptospira spp. occurred at a younger mass/age than SEOV and Bartonella spp. infection, suggesting differences in the transmission dynamics of these pathogens. These data indicate that Norway rats in Salvador serve as reservoir hosts for all three of these zoonotic pathogens and that the high prevalence of leptospiral carriage in Salvador rats poses a high degree of risk to human health.
650 $aInfecção
653 $aRatos da Noruega
700 1 $aPORTER, F. H.
700 1 $aRODRIGUES, G.
700 1 $aFARIAS, H.
700 1 $aFARIA, M. T. de
700 1 $aWUNDER, E. A.
700 1 $aOSIKOWICZ, L. M.
700 1 $aKOSOY, M. Y.
700 1 $aREIS, M. G.
700 1 $aKO, A. I.
700 1 $aCHILDS, J. E.
773 $tVector-Borne and Zoonotic Diseases$gv. 14, n. 1, p. 33-40, Jan. 2014.
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Registro original: |
Embrapa Amazônia Oriental (CPATU) |
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