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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
Data corrente: |
26/06/2013 |
Data da última atualização: |
12/05/2023 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
FERREIRA, L. E.; CASTRO, P. M. N.; CHAGAS, A. C. de S.; FRANÇA, S. C.; BELEBONI, R. O. |
Afiliação: |
L. E. FERREIRA, Universidade de Ribeirão Preto; P. M. N. CASTRO, Universidade de Ribeirão Preto; ANA CAROLINA DE SOUZA CHAGAS, CPPSE; S. C. FRANÇA, Universidade de Ribeirão Preto; R. O. BELEBONI, Universidade de Ribeirão Preto. |
Título: |
In vitro anthelmintic activity of aqueous leaf extract of Annona muricata L. (Annonaceae) against Haemonchus contortus from sheep. |
Ano de publicação: |
2013 |
Fonte/Imprenta: |
Experimental Parasitology, v. 134, n. 3, p. 327-332, 2013. |
DOI: |
10.1016/j.exppara.2013.03.032 |
Idioma: |
Inglês |
Conteúdo: |
Despite the overall progress of sheep farming in Brazil, infections with the gastrointestinal parasite Haemonchus contortus represent one the most important problems in sheep production, aggravated by the increasing resistance of nematodes to traditional anthelmintic drugs caused by inadequate sheep flock management by breeders. Ethnopharmacological data indicate Annona muricata as a promising alternative for the control of gastrointestinal nematodes because of its general anthelmintic properties. The aim of this work was to evaluate the in vitro anthelmintic effects of A. muricata aqueous leaf extract against eggs, infective larvae and adult forms of parasitic nematode H. contortus. At higher doses, A. muricata extract showed 84.91% and 89.08% of efficacy in egg hatch test (EHT) and larval motility test (LMT), respectively. In the adult worm motility test, worms were completely immobilized within the first 6-8 h of nematode exposition to different dilutions of extract. Phytochemical analysis indicated the presence of phenolic compounds in A. muricata aqueous leaf extract that may be responsible for the anthelmintic effects observed. Moreover those results validate the traditional use of A. muricata as a natural anthelmintic and then the pharmacological potential of its compounds for future in vivo investigations. |
Palavras-Chave: |
A muricata; Anthelmintics Gastrointestinal nematodes; H contortus. |
Thesaurus Nal: |
medicinal plants; phytotherapy. |
Categoria do assunto: |
F Plantas e Produtos de Origem Vegetal |
URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/87508/1/PROCI-2013.00032.pdf
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Marc: |
LEADER 02129naa a2200241 a 4500 001 1960605 005 2023-05-12 008 2013 bl uuuu u00u1 u #d 024 7 $a10.1016/j.exppara.2013.03.032$2DOI 100 1 $aFERREIRA, L. E. 245 $aIn vitro anthelmintic activity of aqueous leaf extract of Annona muricata L. (Annonaceae) against Haemonchus contortus from sheep.$h[electronic resource] 260 $c2013 520 $aDespite the overall progress of sheep farming in Brazil, infections with the gastrointestinal parasite Haemonchus contortus represent one the most important problems in sheep production, aggravated by the increasing resistance of nematodes to traditional anthelmintic drugs caused by inadequate sheep flock management by breeders. Ethnopharmacological data indicate Annona muricata as a promising alternative for the control of gastrointestinal nematodes because of its general anthelmintic properties. The aim of this work was to evaluate the in vitro anthelmintic effects of A. muricata aqueous leaf extract against eggs, infective larvae and adult forms of parasitic nematode H. contortus. At higher doses, A. muricata extract showed 84.91% and 89.08% of efficacy in egg hatch test (EHT) and larval motility test (LMT), respectively. In the adult worm motility test, worms were completely immobilized within the first 6-8 h of nematode exposition to different dilutions of extract. Phytochemical analysis indicated the presence of phenolic compounds in A. muricata aqueous leaf extract that may be responsible for the anthelmintic effects observed. Moreover those results validate the traditional use of A. muricata as a natural anthelmintic and then the pharmacological potential of its compounds for future in vivo investigations. 650 $amedicinal plants 650 $aphytotherapy 653 $aA muricata 653 $aAnthelmintics Gastrointestinal nematodes 653 $aH contortus 700 1 $aCASTRO, P. M. N. 700 1 $aCHAGAS, A. C. de S. 700 1 $aFRANÇA, S. C. 700 1 $aBELEBONI, R. O. 773 $tExperimental Parasitology$gv. 134, n. 3, p. 327-332, 2013.
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Registro original: |
Embrapa Pecuária Sudeste (CPPSE) |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Recursos Genéticos e Biotecnologia. Para informações adicionais entre em contato com cenargen.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Recursos Genéticos e Biotecnologia. |
Data corrente: |
05/05/1997 |
Data da última atualização: |
22/07/2019 |
Autoria: |
CARNEIRO, V. T. C.; PELLETIER, G.; SMALL, I. |
Afiliação: |
EMBRAPA-CENARGEN. |
Título: |
Effects of 5' - flanking sequences on the in vivo expression of a Phaseolus vulgaris tRNA Leugene. |
Ano de publicação: |
1993 |
Fonte/Imprenta: |
In: ENCONTRO BRASILEIRO DE BIOTECNOLOGIA VEGETAL, 1., 1993, Brasilia.Programas e resumos. Brasilia: EMBRAPA-CENARGEN, 1993. Poster 015. |
Idioma: |
Inglês |
Palavras-Chave: |
Efect; Efeito. |
Thesagro: |
Gene; Phaseolus Vulgaris; RNA. |
Categoria do assunto: |
-- |
Marc: |
LEADER 00607nam a2200181 a 4500 001 1170828 005 2019-07-22 008 1993 bl uuuu u01u1 u #d 100 1 $aCARNEIRO, V. T. C. 245 $aEffects of 5' - flanking sequences on the in vivo expression of a Phaseolus vulgaris tRNA Leugene. 260 $aIn: ENCONTRO BRASILEIRO DE BIOTECNOLOGIA VEGETAL, 1., 1993, Brasilia.Programas e resumos. Brasilia: EMBRAPA-CENARGEN, 1993. Poster 015.$c1993 650 $aGene 650 $aPhaseolus Vulgaris 650 $aRNA 653 $aEfect 653 $aEfeito 700 1 $aPELLETIER, G. 700 1 $aSMALL, I.
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