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Registro Completo |
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Biblioteca(s): |
Embrapa Caprinos e Ovinos. |
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Data corrente: |
08/11/2023 |
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Data da última atualização: |
16/11/2023 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
SOUSA, N. P.; LIMA, A. M. C.; ARAÚJO, J. B. de; ANDRADE, I. M.; FERRANTE, M.; FACCIOLI-MARTINS, P. Y. |
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Afiliação: |
NIRLIR PLÁCIDO SOUSA; ANA MILENA CÉSAR LIMA; JAMILE BEZERRA DE ARAÚJO; ISABELLA MAGALHÃES ANDRADE; MARCOS FERRANTE; PATRICIA YOSHIDA FACCIOLI MARTINS, CNPC. |
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Título: |
Determinação do ponto de corte epidemiológico, curva de morte e estimativa do índice farmacocinético/farmacodinâmico da cloxacilina em Corynebacterium pseudotuberculosis. |
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Ano de publicação: |
2023 |
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Fonte/Imprenta: |
In: ENCONTRO DE INICIAÇÃO CIENTÍFICA DA EMBRAPA CAPRINOS E OVINOS, 11., 2022, Sobral. Anais... Sobral: Embrapa Caprinos e Ovinos, 2023. p. 39-40. (Embrapa Caprinos e Ovinos. Eventos técnicos & científicos). |
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Idioma: |
Português |
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Conteúdo: |
A linfadenite caseosa (LC) é uma doença infectocontagiosa causada pela bactéria Corynebacterium pseudotuberculosis. O tratamento convencional é a drenagem cirúrgica do abscesso e cauterização química com tintura de iodo a 10%, que é caro (mão de obra e materiais), laborioso e apresenta uma baixa biosseguridade. Nesse contexto, decidiu-se validar uma nova alternativa terapêutica para o tratamento da LC em caprinos de forma sustentável, biossegura e de baixo risco ambiental. Essa tecnologia é baseada em nanopartículas contendo antibiótico à base de cloxacilina, para o tratamento de abscessos precoces fechados, pela liberação prolongada, controlada e direcionada do medicamento. Para tanto, é necessário determinar um regime de doses de cloxacilina para o tratamento, por meio da determinação do ponto de corte epidemiológico de cloxacilina e da curva de morte de cepas de C. pseudotuberculosis, objetivo do presente trabalho. Foram utilizados 35 isolados de campo de C. pseudotuberculosis, oriundos da coleção de microrganismos patogênicos de caprinos e ovinos. |
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Palavras-Chave: |
Antibiotic therapy; Antibioticoterapia; Antimicrobial susceptibility; CBM; CIM; Cloxacilina; Nanopartículas; Susceptibilidade antimicrobiana. |
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Thesagro: |
Caprino; Corynebacterium Pseudotuberculosis; Doença Animal; Farmacologia; Linfadenite Caseosa; Tratamento. |
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Thesaurus Nal: |
Caseous lymphadenitis; Goat diseases; Goats; Pharmacology. |
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Categoria do assunto: |
H Saúde e Patologia |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/doc/1157978/1/CNPC-2023-Determinacao-do-ponto-de-corte.pdf
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Marc: |
LEADER 02456nam a2200385 a 4500
001 2157978
005 2023-11-16
008 2023 bl uuuu u00u1 u #d
100 1 $aSOUSA, N. P.
245 $aDeterminação do ponto de corte epidemiológico, curva de morte e estimativa do índice farmacocinético/farmacodinâmico da cloxacilina em Corynebacterium pseudotuberculosis.$h[electronic resource]
260 $aIn: ENCONTRO DE INICIAÇÃO CIENTÍFICA DA EMBRAPA CAPRINOS E OVINOS, 11., 2022, Sobral. Anais... Sobral: Embrapa Caprinos e Ovinos, 2023. p. 39-40. (Embrapa Caprinos e Ovinos. Eventos técnicos & científicos).$c2023
520 $aA linfadenite caseosa (LC) é uma doença infectocontagiosa causada pela bactéria Corynebacterium pseudotuberculosis. O tratamento convencional é a drenagem cirúrgica do abscesso e cauterização química com tintura de iodo a 10%, que é caro (mão de obra e materiais), laborioso e apresenta uma baixa biosseguridade. Nesse contexto, decidiu-se validar uma nova alternativa terapêutica para o tratamento da LC em caprinos de forma sustentável, biossegura e de baixo risco ambiental. Essa tecnologia é baseada em nanopartículas contendo antibiótico à base de cloxacilina, para o tratamento de abscessos precoces fechados, pela liberação prolongada, controlada e direcionada do medicamento. Para tanto, é necessário determinar um regime de doses de cloxacilina para o tratamento, por meio da determinação do ponto de corte epidemiológico de cloxacilina e da curva de morte de cepas de C. pseudotuberculosis, objetivo do presente trabalho. Foram utilizados 35 isolados de campo de C. pseudotuberculosis, oriundos da coleção de microrganismos patogênicos de caprinos e ovinos.
650 $aCaseous lymphadenitis
650 $aGoat diseases
650 $aGoats
650 $aPharmacology
650 $aCaprino
650 $aCorynebacterium Pseudotuberculosis
650 $aDoença Animal
650 $aFarmacologia
650 $aLinfadenite Caseosa
650 $aTratamento
653 $aAntibiotic therapy
653 $aAntibioticoterapia
653 $aAntimicrobial susceptibility
653 $aCBM
653 $aCIM
653 $aCloxacilina
653 $aNanopartículas
653 $aSusceptibilidade antimicrobiana
700 1 $aLIMA, A. M. C.
700 1 $aARAÚJO, J. B. de
700 1 $aANDRADE, I. M.
700 1 $aFERRANTE, M.
700 1 $aFACCIOLI-MARTINS, P. Y.
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Registro original: |
Embrapa Caprinos e Ovinos (CNPC) |
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Registro Completo
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Biblioteca(s): |
Embrapa Meio Ambiente. |
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Data corrente: |
09/01/2019 |
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Data da última atualização: |
09/01/2019 |
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Tipo da produção científica: |
Resumo em Anais de Congresso |
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Autoria: |
CONGIO, G. F. S.; CHIAVEGATO, M. B.; BATALHA, C. D. A.; BERNDT, A.; FRIGHETTO, R. T. S.; SILVA, S. C. da. |
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Afiliação: |
Guilhermo F. de. S. Congio, USP; Marília B. Chiavegato, pós-doctouranda USP; Camila D. A. Batalha, USP; ALEXANDRE BERNDT, CPPSE; ROSA TOYOKO SHIRAISHI FRIGHETTO, CNPMA; Sila C. da Silva, USP. |
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Título: |
Effect of grazing frequency on enteric methane emissions, output of milk constituents and milk yield. |
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Ano de publicação: |
2018 |
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Fonte/Imprenta: |
In: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 54., 2017, Foz do Iguaçu, PR. Proceedings... Foz do Iguaçu, PR: SBZ, 2017. |
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Páginas: |
p. 587. |
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Idioma: |
Português |
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Conteúdo: |
Grazing management changes sward structure, affecting forage morphological characteristics and nutritive value, and ultimately animal performance and enteric methane (CH4) emissions. The objective of this study was to evaluate enteric methane emissions and animal performance of lactating dairy cows grazing elephant grass (Pennisetum purpureum Schum. cv. Cameroon). Treatments corresponded to strategies of rotational grazing characterized by two pre-grazing targets; 95% and maximum canopy light interception (LI95% and LIMax, respectively). Post-grazing target corresponded to 50% of the pre-grazing targets. Twenty-two midlactation Holstein × Jersey cows (488 ± 60 kg) were stratified by body weight, days in milk (126 ± 90 days), lactation number (2.3 ± 1.2), and daily milk yield (20.3 ± 2.6 kg d-1) in a completely randomized design (n = 11). The 2.5 ha experimental area was divided into two sets of 18 paddocks (700 m2). Concentrate was offered twice daily before milking based on the average milk production of each group (1 kg of concentrate:3 kg of milk). Enteric CH4 emissions were collected using the sulfur hexafluoride (SF6) tracer gas method. Dry matter intake (DMI) was determined using titanium dioxide as a marker. Sampling occurred during the grazing season from December 2015 to April 2016. Results were analyzed using the PROC MIXED of SAS (? = 0.05). There were no treatment effects on DMI (18.4 kg d-1, on average; P = 0.090) nor on daily CH4 emissions (304.9 g d-1 on average; P = 0.136). Therefore, there were no treatment effects on enteric CH4 emissions per unit of feed consumed (17.3 g CH4 kg DMI-1). However, cows grazing LI95% swards had greater milk (17.5 vs 14.6 kg d-1; P = 0.043), protein (0.55 vs 0.47 kg d-1; P = 0.029), fat (0.66 vs 0.55 kg d-1; P = 0.027), and milk solids yield (2.15 vs 1.79 kg d-1; P = 0.019). Consequently, the LI95% target resulted in lower enteric CH4 emissions per unit of milk produced (16.7 vs 23.4 g CH4 L-1, P = 0.002), per unit of milk protein (528.1 vs 703.5 g CH4 kg-1; P = 0.003), per unit of milk fat (437.9 vs 606.5 g CH4 kg-1; P = 0.001), and per unit of milk solids yield (135.2 vs 186.1 g CH4 kg-1; P = 0.001). Grazing management based on the LI95% pre-grazing target resulted in increased output of milk constituents and milk yield, whilst reducing CH4 emissions per unit of final product. These results are likely associated with increased forage nutritive value in LI95% swards, since no effects of pre-grazing targets were observed on DMI. MenosGrazing management changes sward structure, affecting forage morphological characteristics and nutritive value, and ultimately animal performance and enteric methane (CH4) emissions. The objective of this study was to evaluate enteric methane emissions and animal performance of lactating dairy cows grazing elephant grass (Pennisetum purpureum Schum. cv. Cameroon). Treatments corresponded to strategies of rotational grazing characterized by two pre-grazing targets; 95% and maximum canopy light interception (LI95% and LIMax, respectively). Post-grazing target corresponded to 50% of the pre-grazing targets. Twenty-two midlactation Holstein × Jersey cows (488 ± 60 kg) were stratified by body weight, days in milk (126 ± 90 days), lactation number (2.3 ± 1.2), and daily milk yield (20.3 ± 2.6 kg d-1) in a completely randomized design (n = 11). The 2.5 ha experimental area was divided into two sets of 18 paddocks (700 m2). Concentrate was offered twice daily before milking based on the average milk production of each group (1 kg of concentrate:3 kg of milk). Enteric CH4 emissions were collected using the sulfur hexafluoride (SF6) tracer gas method. Dry matter intake (DMI) was determined using titanium dioxide as a marker. Sampling occurred during the grazing season from December 2015 to April 2016. Results were analyzed using the PROC MIXED of SAS (? = 0.05). There were no treatment effects on DMI (18.4 kg d-1, on average; P = 0.090) nor on daily CH4 emissions (304.9 g d-1 on avera... Mostrar Tudo |
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Palavras-Chave: |
Light interception. |
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Thesagro: |
Metano; Pennisetum Purpureum; Vaca Leiteira. |
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Thesaurus NAL: |
Dairy cows; Emissions; Methane; Pennisetum. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/190029/1/RA-FrighettoRTS-54-RASBZ-2017-p587.pdf
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Marc: |
LEADER 03403nam a2200277 a 4500
001 2103344
005 2019-01-09
008 2018 bl uuuu u00u1 u #d
100 1 $aCONGIO, G. F. S.
245 $aEffect of grazing frequency on enteric methane emissions, output of milk constituents and milk yield.$h[electronic resource]
260 $aIn: REUNIÃO ANUAL DA SOCIEDADE BRASILEIRA DE ZOOTECNIA, 54., 2017, Foz do Iguaçu, PR. Proceedings... Foz do Iguaçu, PR: SBZ$c2017
300 $ap. 587.
520 $aGrazing management changes sward structure, affecting forage morphological characteristics and nutritive value, and ultimately animal performance and enteric methane (CH4) emissions. The objective of this study was to evaluate enteric methane emissions and animal performance of lactating dairy cows grazing elephant grass (Pennisetum purpureum Schum. cv. Cameroon). Treatments corresponded to strategies of rotational grazing characterized by two pre-grazing targets; 95% and maximum canopy light interception (LI95% and LIMax, respectively). Post-grazing target corresponded to 50% of the pre-grazing targets. Twenty-two midlactation Holstein × Jersey cows (488 ± 60 kg) were stratified by body weight, days in milk (126 ± 90 days), lactation number (2.3 ± 1.2), and daily milk yield (20.3 ± 2.6 kg d-1) in a completely randomized design (n = 11). The 2.5 ha experimental area was divided into two sets of 18 paddocks (700 m2). Concentrate was offered twice daily before milking based on the average milk production of each group (1 kg of concentrate:3 kg of milk). Enteric CH4 emissions were collected using the sulfur hexafluoride (SF6) tracer gas method. Dry matter intake (DMI) was determined using titanium dioxide as a marker. Sampling occurred during the grazing season from December 2015 to April 2016. Results were analyzed using the PROC MIXED of SAS (? = 0.05). There were no treatment effects on DMI (18.4 kg d-1, on average; P = 0.090) nor on daily CH4 emissions (304.9 g d-1 on average; P = 0.136). Therefore, there were no treatment effects on enteric CH4 emissions per unit of feed consumed (17.3 g CH4 kg DMI-1). However, cows grazing LI95% swards had greater milk (17.5 vs 14.6 kg d-1; P = 0.043), protein (0.55 vs 0.47 kg d-1; P = 0.029), fat (0.66 vs 0.55 kg d-1; P = 0.027), and milk solids yield (2.15 vs 1.79 kg d-1; P = 0.019). Consequently, the LI95% target resulted in lower enteric CH4 emissions per unit of milk produced (16.7 vs 23.4 g CH4 L-1, P = 0.002), per unit of milk protein (528.1 vs 703.5 g CH4 kg-1; P = 0.003), per unit of milk fat (437.9 vs 606.5 g CH4 kg-1; P = 0.001), and per unit of milk solids yield (135.2 vs 186.1 g CH4 kg-1; P = 0.001). Grazing management based on the LI95% pre-grazing target resulted in increased output of milk constituents and milk yield, whilst reducing CH4 emissions per unit of final product. These results are likely associated with increased forage nutritive value in LI95% swards, since no effects of pre-grazing targets were observed on DMI.
650 $aDairy cows
650 $aEmissions
650 $aMethane
650 $aPennisetum
650 $aMetano
650 $aPennisetum Purpureum
650 $aVaca Leiteira
653 $aLight interception
700 1 $aCHIAVEGATO, M. B.
700 1 $aBATALHA, C. D. A.
700 1 $aBERNDT, A.
700 1 $aFRIGHETTO, R. T. S.
700 1 $aSILVA, S. C. da
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Embrapa Meio Ambiente (CNPMA) |
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